Gmel005249.1
Basic Information
- Insect
- Galleria mellonella
- Gene Symbol
- ZEB2
- Assembly
- GCA_958496185.1
- Location
- OY292286.1:18265553-18274793[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 1.1 74 4.6 1.0 3 22 459 478 457 481 0.90 2 13 1 65 4.7 1.9 2 19 503 520 502 526 0.91 3 13 0.00075 0.049 14.6 4.6 1 23 540 563 540 563 0.98 4 13 0.011 0.74 10.8 2.5 1 23 568 592 568 592 0.91 5 13 3.2 2.1e+02 3.1 0.4 2 23 613 637 612 637 0.87 6 13 0.0012 0.076 13.9 0.1 2 21 643 662 643 663 0.96 7 13 1.9e-05 0.0013 19.5 1.5 1 23 722 743 722 743 0.98 8 13 0.0019 0.12 13.3 0.4 1 23 749 772 749 772 0.96 9 13 0.002 0.13 13.2 0.5 2 20 799 817 798 819 0.93 10 13 6 3.9e+02 2.3 0.6 9 23 832 846 825 846 0.78 11 13 0.33 21 6.2 9.8 1 21 853 873 853 875 0.95 12 13 0.16 11 7.2 4.8 3 23 883 904 881 904 0.95 13 13 2.4 1.6e+02 3.5 0.9 1 23 910 933 910 933 0.96
Sequence Information
- Coding Sequence
- ATGCTGTCACCGCGCGACGACGATGACGACGACAGCCACTTATGCATCAAATGCAACGCCACTATCATTGGCCTCGACAACTACGTTAAACATAGAAAGCAGAGATGTCAGAAGAAAAGTACTACCTCCAAATCGGATATTCCGAGCATTAATCCATTGGAACCTACTTACAGCCTTGGAGCTGATGTTTTTTTCCAGTCCTTGGAGTTACAAAGTAGTGTTAAGAAACCCACATTGGCCAGACTTACACCACCCATACCCACTTCTAAAGTAGGTATAGACACAAAAAGTACATTGACTGAACCCTCAACTTCTAGGGATCTACCAAGAATGAGCCCTTTAGAGAGCAACTTAGGTGGCGAAGACTGGATTGGTGGTCATAGTTTAAGAATAGGTATGAACGAAGATAATCAAACAAAGTTGATAAATGCAGTGGCTAGTATTAGTGGTTCGGTTAAGAAAGATATTCCGACTTCTTCTTATAATATCGAAGGTTTTAACGATTTTAAAGGCGACGAAGATTTTGATGAATCGGAAGATTCAGAGGACGAAGACGAGGATGAACCTCATGCTACTGGAGAAAAGTGGAAGCCTCCACCAAATTATACAGGCGGTAAATGGAGACCTGCATCTCCGGAAAATGAAGATTGGGATATGCGGGACGAACAAGAGCATATGGGCGGTAAATGGAAATCATTTATAACAAATGACcgtgatgatgattatgatgctCCGCCACCAGGCCACACCAAAGGTAAATGGGTACCTGGAGCACATGAAAAAACACAAATAATGCAACCGACTATACAAACAAAGGGCACAGTGCAGTACTGGTGTGGGCCTTGTAACCGGCGTCTGGGTTCAAAGGCTATATACGACAAACATTTAATGTCAAGCCTACATATGAGAAAAGTGCTACCCGAACGCGAGTTGGAATTCTCAGGACATttagaatcattaaaaaatatgacggAAAAACGATCTATCCGTTCTACGCGATTTTTAAATAGAAGCGTATATATTCAGTCACATGCAAAGAAGCCACGCGTATCTGGAAAATTAAATGTGAagcttcaaattaaaaaaagaaaacggaAGTCTGTTTTTGTACATTGCTGTGGGTGCAAATCTCGCGTGAGACAGCATCTAATGGGAAAACACTTGATATCTCATTATCACTTTAGAAAAGCCACAGACACACAGAGCAGTATATATAAACAGTTAATTCTTGAAAATATAGATGCTATTGTCCACCAGTCACCATTTCAATGTAGtccatgtaaattttatactaacTGGCTCTCAAACTTTATGCAGCATTGGTTTTCTGAAGAACATGTACAGAAAATGGCGCAAACAGAAGGTAGATATTGGTGCTCATTTTGTAAATACGAATGTGAAACATCTGAAGAAATGTCAGAGCACATGTCAAGCTTGGAACATAGTGAAGTAGTTGCAGTTATTAATAGGTCTATGCCTATAATTATACGAAAGAAAAGCGTGTTGAGATGTGAAACTTGTAATGTAGAGTTTCGATACAACATGGAGATAAAACGACATTGTCAGAAAACAGGACACGCTTTGGCCTATACTGCTACTGATAGTTATCAGGAATTACACAAATGTAAACactgtaaagttaaatttaagTCTTCTCTATCGCTGGCAGCCCATTTAAAGACTATACATAAGCAAAAAGCGTTTTTCTGTTTAGTTTGTTCAAAAACTTTCAACTCCTCGGAGGAAGCAAAACATCATCGTCAAACTTCTGAGCACAGAATTAGAAAGAAAGAGATATTGAAGGAAAAAGGTTTAATTACGAAAGATTTGACCAAAAAGTGTCCTTACTGTAAAGAtgaattgtttttaaagaatatattggAGTTAAAAGATCACATTAGAAGAGTGCATCCACACATTAAAAGAAAATGCCCTAAATGCGGTATGTCATTCATCTTGTCGCAAGAAGTAACTCGTCATATCAGGAACAATGCTTGCCAATTTCGTAACACTAATCCGCCGAATTCCTCCATATTGTGGAACTGCAGCCAGTGCGTCTTCACAACAGACTCCCAAGCCGAGTGTTTCTTCCACGAAGTTTTACATTCAGATCCAGTAAGAGACATTCGCAAAGTTGGCAATAAAGAGAAAGTGTATGAGAAATATATATGTCCAATTTGTCATAAAACATTCAAGAAGGCATCTCTACGTGAGCATTTGAGGATACACACTTCTGAACGACCCTTCGTCTGTGCCACGTGTGGAGCCAATTTTACTAGATTGACCAGTTTAGTTAATCATAACAAAAGCCAACACAAGATAGATACCGCCAGTAATCAGATTACAAAACCAGAGAAGGTTATTGAGAGTACAGATACGAAGACACAAGACTGGAAATGCAGTAAATGCCCGAGCAGTTTCCCCAACAGAACTTCGTTGAGAAGACACGCTTCAAAATGTGGCAGTATGGGCCAAAAATGCCCACATGATCAATGCACCTATGTATCAGCTAACTTAGTCagaCATCGTCGAGCTCATGGTGAACAAATGAAAAATCACCAGTGCCAGCTATGTACGTTTAAAACTAATCACTCCAGCCACCTGAAGAGGCACATGCTCTGCCATAAGGGGCTGAAGCCTTACGGTTGTCCGCACTGCCAGTTTGTTTGTGGTAGCTTGGAGAACCTCCGCAAACACGCCCACCGACGACATCCCGGACTGCCGCTGTACCGCTGCGAGTGTTGCGAATTCAGCACCGACATGGCGGCTCTACTGCGCAGCCATCTCACCACAGTTCATTCAGATAAATATGACACTAGCACCGCTTTCAATGTCGTCAAACTACATTTGATGACTAGTGAGTACAAGAAAGACATTGGTGATGAGTGA
- Protein Sequence
- MLSPRDDDDDDSHLCIKCNATIIGLDNYVKHRKQRCQKKSTTSKSDIPSINPLEPTYSLGADVFFQSLELQSSVKKPTLARLTPPIPTSKVGIDTKSTLTEPSTSRDLPRMSPLESNLGGEDWIGGHSLRIGMNEDNQTKLINAVASISGSVKKDIPTSSYNIEGFNDFKGDEDFDESEDSEDEDEDEPHATGEKWKPPPNYTGGKWRPASPENEDWDMRDEQEHMGGKWKSFITNDRDDDYDAPPPGHTKGKWVPGAHEKTQIMQPTIQTKGTVQYWCGPCNRRLGSKAIYDKHLMSSLHMRKVLPERELEFSGHLESLKNMTEKRSIRSTRFLNRSVYIQSHAKKPRVSGKLNVKLQIKKRKRKSVFVHCCGCKSRVRQHLMGKHLISHYHFRKATDTQSSIYKQLILENIDAIVHQSPFQCSPCKFYTNWLSNFMQHWFSEEHVQKMAQTEGRYWCSFCKYECETSEEMSEHMSSLEHSEVVAVINRSMPIIIRKKSVLRCETCNVEFRYNMEIKRHCQKTGHALAYTATDSYQELHKCKHCKVKFKSSLSLAAHLKTIHKQKAFFCLVCSKTFNSSEEAKHHRQTSEHRIRKKEILKEKGLITKDLTKKCPYCKDELFLKNILELKDHIRRVHPHIKRKCPKCGMSFILSQEVTRHIRNNACQFRNTNPPNSSILWNCSQCVFTTDSQAECFFHEVLHSDPVRDIRKVGNKEKVYEKYICPICHKTFKKASLREHLRIHTSERPFVCATCGANFTRLTSLVNHNKSQHKIDTASNQITKPEKVIESTDTKTQDWKCSKCPSSFPNRTSLRRHASKCGSMGQKCPHDQCTYVSANLVRHRRAHGEQMKNHQCQLCTFKTNHSSHLKRHMLCHKGLKPYGCPHCQFVCGSLENLRKHAHRRHPGLPLYRCECCEFSTDMAALLRSHLTTVHSDKYDTSTAFNVVKLHLMTSEYKKDIGDE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00008504;
- 90% Identity
- -
- 80% Identity
- -