Gmel014955.1
Basic Information
- Insect
- Galleria mellonella
- Gene Symbol
- -
- Assembly
- GCA_958496185.1
- Location
- OY292299.1:6967766-6972775[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.0011 0.073 14.0 0.4 1 23 310 333 310 333 0.92 2 12 0.006 0.39 11.7 1.8 1 19 354 372 354 376 0.90 3 12 9.1e-05 0.006 17.4 4.1 2 23 382 403 381 403 0.96 4 12 0.00049 0.032 15.1 0.2 1 23 407 430 407 430 0.96 5 12 2.8 1.9e+02 3.3 1.6 3 23 435 455 433 455 0.90 6 12 0.00054 0.036 15.0 0.4 2 23 542 563 541 563 0.95 7 12 0.35 23 6.2 0.2 2 23 583 605 582 605 0.96 8 12 1.1e-06 7.4e-05 23.4 4.1 1 23 611 633 611 633 0.98 9 12 0.0015 0.1 13.6 1.7 2 23 639 660 638 660 0.96 10 12 0.0069 0.45 11.5 3.2 2 21 667 686 666 689 0.94 11 12 8.4 5.5e+02 1.8 2.0 1 19 697 715 697 720 0.87 12 12 0.057 3.7 8.6 2.1 3 19 729 745 728 750 0.90
Sequence Information
- Coding Sequence
- atggaatctgGTACCCCGCTTGTAGACTCCGATACTATATACCCAGTACTCCTCATACCCAGAAAGTGTACGACTTTAGAAACGAACTGTGACGCTTCtgataatgtttttattgaCTTGAATATAACTTCACCAGATATAGAAGGCAATGAAATGTGTCTGTACTCTGGTTTTTGTAACGTTAAATTAATAGACAACTATGATGTGAGTATTCATCATGTCAGTTCACCTGATAATAGTGGGTCATCCAGTTGCATTGATATCGAACAGCCGCCGCTGATAATTAGTGAGCAAGGCACGGGATTCCCTTATAACCAGTCCAAAGTCTGGATAGACCCAGTTAGAAGTCCACATGTATATAACCATTACGATACAACAGAAACTCAGGAATACTCTGTATGTCGTAAGTCACACACAAGTCATATAACTGTTGAACAACACAGTACGTATATAACCCAGAATGTGTTCAATTATAAAGAGTCGATCCAATACTCGCCCACAGAAGATTTTGAGCACAAAAAGTTCAGGAAACCTCATGCGTCCGAGACAGTTACTCAACAACCATCTGCCAACCAAGATgggaataatttgaatttatatgaaGATAATGAGTTTGAATGTGGCGTGTTTCTCTCTCAACTCTCTGAGGAAATAATGaacgaaaaagaaaataaagccAAAGATGAGCGTAAATACATAGGGCTGCAGAGTGAAAATGGTGCATTGAAGCAACTCATGTCGTCTGATATCCAATCTGCATCTAAACAACGTAAGACGATCCTGTTTCTCGGTCACGATTCTCACTGTGGCCAAACAATACAGAAGATTGCGGTCAATGACCCATCCTTAGAATGTTCAAAAGTTGGAAATTTGAACCCAGCAAATATTAAGACTGatgATGTCAAAGTTAATCGTAATCAGAAAAAATATCAGTGTGATAAATGTAAgcaaatatttaatcaaatagCTGCATTCAAACAACATATGGTCGGTAATCACAATATAGCAAAAAGTTTGAGCATGTATGATATTGAAAATGGTACTGTGAGTGAAGTTAAATTTATGTGCACCGAATGTGGGAAGACCCTTAAGAGTCAGGAAAAGTTTGAAATCCACTGCATGGGGCATGGTGATCCAGATTTAGAATGTAATAAGTGCCATAAAGTGTTCGCATCAAAATTCACTTTACGTACACACCGGAAGTTACATTACAGAAAATACCCATGCAATTTCTGTTACAAAACATTTTCAGAGGTCGAAGATTTAAAAGCGCACGTTgcgaaaatacattttattttcttgtgtattcattgtaattttacaactaagaattatattgaattaacaGAACATGAACAATTACATAGTGGTCAAATTGTGCCCAATGATTCTAGTGAAACCGATCGTAATGATTCGTTTGTGAATGACATATGCAACGAGACAGGCAATATTGTTGAGCCACTTGAAATTGAGAATTTAAAGTTAGAAAATCAACTTACCGCTTCCAGTAAGAACTTcgatgaagaaataaaaaaagcagaTTCTGTTATAGCTAAAGTGATATCAAATAAGATTTTCCTCTTGCACTCTAAAAAGGTTAGAAAACACAGGAGATACAATAAGtCCTGTGACGTATGCTTCAAGATGTTCGACCGGATTGGTGATCTTAAAAGACATCTTATAGAACACGTGATACGAAGTACCCTCGCCAAGACGCCGGTGAACAAGAATGGCACACTCAACATACAGTGTGAGGTATGTCAAGTTGAAACATTCACTAAAATAGACCGTTACAAAGCCCACTTGCGTGAACACGCCAAACTAACGCTGTACAAATGTACATTTTGTGACAAATCGTTCAGTGATTCCAGTAATTTTTCTAAACACAAGAAGATCCACGGCACCACATACCTACAGTGCGATTTATGCCAAAGAAAATTCAACTCTAAGAAAATGATCACACAGCACATGGAGTATCACAATAAACACTCGCCGGTCCAATGCCAATACTGTGATAAGATATTTCATTTTGAATCTATGCTCAATAAACACGTCAAGTGTGCTCACAGCAAGGAAGTGTGCAGCCGATTCAAATGCAGATTCTGTTTTCAATACTTTAAGACTTTGAAGGAGAAATGGGACCACGAATGGACCATTCATAATGTGAGAAAGATGATAGTAGACTGCCTAATATGCGATTCTAAATTTCGAAAATACTCGGAACTGAAAAGACATTGTATAATTACACATGACATGGATATACCGCCCGcaaaaaagcttttaaaaaaaaagagaaataaaaatcaatgctggaaatag
- Protein Sequence
- MESGTPLVDSDTIYPVLLIPRKCTTLETNCDASDNVFIDLNITSPDIEGNEMCLYSGFCNVKLIDNYDVSIHHVSSPDNSGSSSCIDIEQPPLIISEQGTGFPYNQSKVWIDPVRSPHVYNHYDTTETQEYSVCRKSHTSHITVEQHSTYITQNVFNYKESIQYSPTEDFEHKKFRKPHASETVTQQPSANQDGNNLNLYEDNEFECGVFLSQLSEEIMNEKENKAKDERKYIGLQSENGALKQLMSSDIQSASKQRKTILFLGHDSHCGQTIQKIAVNDPSLECSKVGNLNPANIKTDDVKVNRNQKKYQCDKCKQIFNQIAAFKQHMVGNHNIAKSLSMYDIENGTVSEVKFMCTECGKTLKSQEKFEIHCMGHGDPDLECNKCHKVFASKFTLRTHRKLHYRKYPCNFCYKTFSEVEDLKAHVAKIHFIFLCIHCNFTTKNYIELTEHEQLHSGQIVPNDSSETDRNDSFVNDICNETGNIVEPLEIENLKLENQLTASSKNFDEEIKKADSVIAKVISNKIFLLHSKKVRKHRRYNKSCDVCFKMFDRIGDLKRHLIEHVIRSTLAKTPVNKNGTLNIQCEVCQVETFTKIDRYKAHLREHAKLTLYKCTFCDKSFSDSSNFSKHKKIHGTTYLQCDLCQRKFNSKKMITQHMEYHNKHSPVQCQYCDKIFHFESMLNKHVKCAHSKEVCSRFKCRFCFQYFKTLKEKWDHEWTIHNVRKMIVDCLICDSKFRKYSELKRHCIITHDMDIPPAKKLLKKKRNKNQCWK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -