Basic Information

Insect: Galleria mellonella
Gene Symbol: zfh1
Assembly: GCA_958496185.1
Location: OY292290.1:274387-278763[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.013 0.87 10.6 0.4 1 23 44 66 44 66 0.95

2 8 6.2e-06 0.0004 21.1 2.8 1 23 77 99 77 99 0.98

3 8 1.9e-06 0.00012 22.7 6.2 1 23 108 130 108 130 0.99

4 8 0.00013 0.0088 16.9 1.0 1 21 136 156 136 157 0.95

5 8 0.00021 0.013 16.3 0.7 1 21 424 444 424 445 0.93

6 8 1e-05 0.00066 20.4 1.1 1 23 748 770 748 770 0.94

7 8 8.4e-05 0.0055 17.5 7.6 1 23 776 798 776 798 0.98

8 8 0.054 3.5 8.7 8.1 1 21 804 824 804 825 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.013	0.87	10.6	0.4	1	23	44	66	44	66	0.95
2	8	6.2e-06	0.0004	21.1	2.8	1	23	77	99	77	99	0.98
3	8	1.9e-06	0.00012	22.7	6.2	1	23	108	130	108	130	0.99
4	8	0.00013	0.0088	16.9	1.0	1	21	136	156	136	157	0.95
5	8	0.00021	0.013	16.3	0.7	1	21	424	444	424	445	0.93
6	8	1e-05	0.00066	20.4	1.1	1	23	748	770	748	770	0.94
7	8	8.4e-05	0.0055	17.5	7.6	1	23	776	798	776	798	0.98
8	8	0.054	3.5	8.7	8.1	1	21	804	824	804	825	0.96

Sequence Information

Coding Sequence: ATGAGCCAAAGTGAAGCTCGGTCTACCCGTcccgatttcgTCCGTCCGCTGGCCGGCGGCGGGTCGGAGGGCAAGCCGTCCGAGGAGGAGGAGGAGCGGGGCGGGTCCCCGCTGGGCCCCGGCGGGCCCTTCACGTGTAGCCAGTGCCGCGGCGCGTACCCCACGCGCGAGCAGCTCGAGCGACACGAGACCCTGCACTCGCCCAACACACAGGTGGATACACTCAAATATTCGTGCAAGATATGCCACAAGAGCTTCGCGAACGTATACCGACTGCAGCGGCATATGATCAGTCACGACGAGAGCGCCACGCTGCGGAAATTCAAATGCAACGACTGCGACAAGGCGTTTAAGTTCAAACATCATCTGAAGGAACACCTGCGGATACATAGCGGCGAGAAACCCTTCGAATGCGCCAACTGTGGTAAAAAATTCTCCCATTCGGGCTCCTACTCGAGCCATATGACCTCCAAGAAATGTCTCGTCATGAATCTAAAAATGGGACGAATCAAACCAAACAACCCAGCCCTCAACCCAGAAAGAAGTCCTTCGAGAAAGCGAGCTAATGCCATGGTCGCATCTCAACTTAACAACAACATACAACCAAACGGGAGCTCGTTTTTGCCTATTTTACCTAAGTATAACGAGGCAGCAGCCGCTTTCTTCGCTTCTATGTCGTCACAAGAGAATAACTTCCATCGGGCGCCGCTCGGCCAACCTGGCATCAACCCTTTCTACATGCCACCTGGGATGCCTTTGAGTCCTGCTAGTGGAATTACACCTtatagttttcctacttctctTAGTCAACTTTTCGAACAATTGGCATCATCTCAGTATCAACAAAGGAAGATAGAGATGGAGAACCCAATTAGCCCAAAGCACGTGAACACTCCCGTAGATCCAGAAGATATGATCGAAGAAGTCACAGAAGAAGACGACAAACGCTCAGAAGGGAGTGCAGAACTCGTAATGGACATCGAGGATGATGAAGCTTTATCTATAAAGAAGGAGCAAGAAGACCGAGAGAATGAATTAAGATCACCCTCCCGTAATTTCAATTCCGTCCCTTTAAATAACAACGGCCatcaagttaataataataattctggcTTTAACACGATATTAGACTCTGTTAATGCATCAGTGACCAAACATTTCTTTAGGGCAAACATAGAAAAGCTTTCCCCTGTGTCCGGAAATATATGCCCTAGTATAGAATCGCCACCGACACCTCACATAATTGTTAAGGAAGAGCCCGAAGATAACCATAGGTGTATGAAATGTAACGAAACATTCAGTAATAAAAGTGACTTAGTGGACCACGAGAAAGTAGTATGTGGAGGTTTATTTAGAAAACACGAAGGTTTGGCAGCTCAAGTGGCCGAAACGGTAGCATTGAACAGATTAGAAGCAGAAGCTCGAGCCTCTATACAAAGCGGAGTGAGTGCAAGTGAAGACGAAGACTTTATAAGAGAAGATCGcgatgataaaatatctatacatgATAACGATAGAAAAATAAGAGTCCGTACTACACTGAGTGAAGAGCAACAAGCAGTCTTGAAAGAACATTACGCAGTAAACCCGAGACCAAACAgagaagaatttaaaaaaatcgccCAGCAAATTGGACTAGACAACAGAGTAGTACAAGTGTGGTTTCAAAACAATAGAGCTAGAGTGCGGCGGATGACACAAACTTTGGCCATGTCTGACCAGCCACTCGACTTGTCTACTAAGAAGTCGAATCCGTCGGTGACGTCGAGTCCGTCGCCGTCGCCGCCTTGTAGCATTTCTGTTACACATTCCGACACGGAGGAAGCGGTGAACCTCAGTCAAAAATCATCGCGCAGTACGACTCCACACCGTACCAACTATTTGAACACTTATCCACATTCCAATTGCTCCTCTTCTTCTCTCACTGACTTTAGACTATCTCCATCGCCTGGAGAAACTATGAATGCTCAAAAAAGAGAAAGATTATTACTACGTAATATAGCAGTTACACCGATGATGCCTATGgacaaatttattcaatataatgaTATGGCAAACGGTCGATCGCCTCTGCTCAATATGCAGATGCCAACTGACATCAGTCGAGCGTCGAGTCCGTCGTACGAGCGGCCGTCCTGGGCAGACGAGTCTCATCCCGCAAACGATTTCGAAGACGATGCGACTGTACTTAAGAAAAGTAAACTGAAGCAGGGTGCTGAATATAAGGAGGGAGAAGGCCAGTTCGTCTGTGATCAGTGCGACAAAACTTTTGTCAAACAAAGTTCCCTCGCACGACACAAATACGAACATTCAGGACAACGTCCCTATAAATGTTTGGAGTGTCCGAAGGCATTCAAGCATAAACACCACTTGACCGAACACAAGCGGCTGCACACCGGCGAGAAGCCGTTCCAGTGCTGCAAGTGCTTCAAGAAATTCTCCCACTCGGGCTCGTACAGCCAGCACATGAACCACAGATTCGCAATATGCAAGCCTTACAGAGACTAG
Protein Sequence: MSQSEARSTRPDFVRPLAGGGSEGKPSEEEEERGGSPLGPGGPFTCSQCRGAYPTREQLERHETLHSPNTQVDTLKYSCKICHKSFANVYRLQRHMISHDESATLRKFKCNDCDKAFKFKHHLKEHLRIHSGEKPFECANCGKKFSHSGSYSSHMTSKKCLVMNLKMGRIKPNNPALNPERSPSRKRANAMVASQLNNNIQPNGSSFLPILPKYNEAAAAFFASMSSQENNFHRAPLGQPGINPFYMPPGMPLSPASGITPYSFPTSLSQLFEQLASSQYQQRKIEMENPISPKHVNTPVDPEDMIEEVTEEDDKRSEGSAELVMDIEDDEALSIKKEQEDRENELRSPSRNFNSVPLNNNGHQVNNNNSGFNTILDSVNASVTKHFFRANIEKLSPVSGNICPSIESPPTPHIIVKEEPEDNHRCMKCNETFSNKSDLVDHEKVVCGGLFRKHEGLAAQVAETVALNRLEAEARASIQSGVSASEDEDFIREDRDDKISIHDNDRKIRVRTTLSEEQQAVLKEHYAVNPRPNREEFKKIAQQIGLDNRVVQVWFQNNRARVRRMTQTLAMSDQPLDLSTKKSNPSVTSSPSPSPPCSISVTHSDTEEAVNLSQKSSRSTTPHRTNYLNTYPHSNCSSSSLTDFRLSPSPGETMNAQKRERLLLRNIAVTPMMPMDKFIQYNDMANGRSPLLNMQMPTDISRASSPSYERPSWADESHPANDFEDDATVLKKSKLKQGAEYKEGEGQFVCDQCDKTFVKQSSLARHKYEHSGQRPYKCLECPKAFKHKHHLTEHKRLHTGEKPFQCCKCFKKFSHSGSYSQHMNHRFAICKPYRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00281695;
90% Identity: iTF_00007901;
80% Identity: iTF_00736503;