Gmel001636.1
Basic Information
- Insect
- Galleria mellonella
- Gene Symbol
- -
- Assembly
- GCA_958496185.1
- Location
- OY292283.1:10188980-10195538[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.02 1.3 10.1 0.6 2 23 195 217 194 217 0.92 2 11 0.071 4.7 8.3 4.6 1 23 277 300 277 300 0.94 3 11 0.084 5.5 8.1 0.3 5 23 309 327 307 327 0.95 4 11 0.0098 0.64 11.0 2.0 2 23 334 355 333 355 0.96 5 11 8.8e-06 0.00057 20.6 1.6 1 23 363 385 363 385 0.98 6 11 0.00082 0.054 14.4 1.5 1 23 394 417 394 417 0.97 7 11 0.00024 0.016 16.1 0.2 1 23 423 445 423 445 0.97 8 11 5.6e-06 0.00037 21.2 3.2 1 23 451 473 451 473 0.98 9 11 5.6e-05 0.0037 18.1 0.7 1 23 478 500 478 500 0.98 10 11 5.1e-05 0.0033 18.2 6.2 1 23 506 528 506 528 0.97 11 11 0.0017 0.11 13.4 2.4 2 23 535 557 534 557 0.95
Sequence Information
- Coding Sequence
- ATGGATAATGTAAAAGATCTTTGTAGATTATGTGCCAAAAAGGAAGAGCTATCAAAAGATTTATTGGATGTAAATAACaaaagtgtattaaaattaattcaagatTTTGTACAGATAGCCATTATAGAAAATGATGGGCTAcctacaaaaatatgtttaaattgtgAAGAAAAAATAGTATCATTCCAATTATTCATTTTGGAATGTTATAAGGTGCAAGATacccttaaaaaaatatatttagataatttcaACATAAAACATGAAGATGAGTCACTTTTATACACAAATCCTGTTATTAAGTCAGAGGTCAAAGATGAACTTACTGCTGAAGATATTGTGTTAGgtgCTATTGATAATGAGATATCTGAGTATGATGGAGTAGACTTTTCAGTATTTGATGATCATAAAAGTGATGACACTGGTGATGATGACGACGAGGCGGACAATATTACTTTAGCttctttgaaaaaagaaaaagggaaacatattaagaaaaaaaatattagtgaaGAAGCTGCTGCAGACTTTAATGAACTAttgaaaaaatctaatttaaaagtaaaagacTTTGTCAAacTGCATTGTGATATGTGTGATCTGAAAATGAAGACATGGAGTGAGTTGACTGTCCATTATGGCAAAATACACAAAAGGAAACCCTATGTTTTATGTATCTGTGGGTACATAATCCACTCTAAGAGTGTACTATATAAGCATGTTTCGGACCATAAAATAGAAAGTAGCAAGTTACACAATACATCGCAAGATATGGGAAAACCAACGAATGTTAATTATTCTTCACTCAAGATCCGTGATTTTGTTGAtTTTACgtgtaatatttgtaataaaaagcaTTCCAGTTGGTACAGATTAAAATCACACACTTCCTACAATCACAAGGTACTGCCTGTTGTTAAATGCATTTGTGGTATAACGCTTAAATCGAAATCGGTTCTCTATAAACATATTCAAGATCATAGAAATCCAAATGTTTTATGttgTGACAAATGCCCTCGAATAACCAAGACTGTTGAAgctttaaataaacacaaaatgagACATGTTCCTAAATCAGAAAGAAAGTTCTATTGCAATTCTTGTGACAAAGTGTTTAATACGAAAGATGGTTTAAAATCTCACGAAAAATCTCATATACCAATTgaagaaagaaaaatttatCATTGTGAAGTATGTAACCTCAAATTTACGACGCGGTCCTCAGCTGCATCCCACAAACGCGTAGTGCACGATAAGATCAAGAGTTACGTGTGTGACTTGTGTGGCTATGCCTGCGGCACCAGCGGCGAGCTGCGACAACATCGAGCTATACACAGTGATGACAAACCCTTCGTTTGCGGAAAGTGCTTTAAGCCGTTTAAGACACATTCGAACTTGAAGACTCATATTGATACGCACGAAGATACATCGTATACATGCGATGTTTGTAATCGTGTTCTCAACAGTCGACGCACACTAAGAAAACATTTGCTCGTGCACGAAGAAAAATGTAGGCATGTTTGCTCATACTGTCATAAAGCTTTTAAAAGAAGACAAACACTAAAGGTTCACCTGTATACTCACACGGGCGACAAGCCGCTGTCTTGCAAATGGTGCAGCGAGCGGTTCGCGTATGCGTCAACACTCCGCTCACACCGATTGCGCTGTCACCCGGACAAGCTGGCCGCGCAGCCCGCACACTCATACCAGCCCTACCGACATCTGCCCGCACAGGAGGATTATATCAAGAACGACTTAGTGACTATTAACGGAGCAAAGAATGAAACAGAGGCTATGTAA
- Protein Sequence
- MDNVKDLCRLCAKKEELSKDLLDVNNKSVLKLIQDFVQIAIIENDGLPTKICLNCEEKIVSFQLFILECYKVQDTLKKIYLDNFNIKHEDESLLYTNPVIKSEVKDELTAEDIVLGAIDNEISEYDGVDFSVFDDHKSDDTGDDDDEADNITLASLKKEKGKHIKKKNISEEAAADFNELLKKSNLKVKDFVKLHCDMCDLKMKTWSELTVHYGKIHKRKPYVLCICGYIIHSKSVLYKHVSDHKIESSKLHNTSQDMGKPTNVNYSSLKIRDFVDFTCNICNKKHSSWYRLKSHTSYNHKVLPVVKCICGITLKSKSVLYKHIQDHRNPNVLCCDKCPRITKTVEALNKHKMRHVPKSERKFYCNSCDKVFNTKDGLKSHEKSHIPIEERKIYHCEVCNLKFTTRSSAASHKRVVHDKIKSYVCDLCGYACGTSGELRQHRAIHSDDKPFVCGKCFKPFKTHSNLKTHIDTHEDTSYTCDVCNRVLNSRRTLRKHLLVHEEKCRHVCSYCHKAFKRRQTLKVHLYTHTGDKPLSCKWCSERFAYASTLRSHRLRCHPDKLAAQPAHSYQPYRHLPAQEDYIKNDLVTINGAKNETEAM
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00008244;
- 90% Identity
- -
- 80% Identity
- -