Basic Information

Insect: Galleria mellonella
Gene Symbol: ehn-3
Assembly: GCA_958496185.1
Location: OY292296.1:11009595-11016472[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.00058 0.038 14.9 0.1 1 21 166 186 166 190 0.92

2 12 0.0012 0.08 13.9 2.9 1 23 194 217 194 217 0.96

3 12 0.03 2 9.5 1.2 2 23 224 245 223 245 0.86

4 12 1.6e-05 0.001 19.8 3.1 1 23 251 273 251 273 0.98

5 12 5.8e-05 0.0038 18.1 0.8 2 23 281 303 280 303 0.96

6 12 8.4e-06 0.00055 20.7 1.2 1 23 309 331 309 331 0.99

7 12 0.00021 0.014 16.3 4.2 1 23 337 359 337 359 0.98

8 12 9e-05 0.0059 17.5 1.5 1 23 365 387 365 387 0.99

9 12 0.0022 0.14 13.1 3.7 2 23 394 415 393 415 0.94

10 12 0.0042 0.28 12.2 6.7 1 23 421 444 421 444 0.96

11 12 0.013 0.87 10.6 0.4 1 23 479 502 479 502 0.94

12 12 0.00068 0.045 14.7 4.8 1 23 508 531 508 531 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.00058	0.038	14.9	0.1	1	21	166	186	166	190	0.92
2	12	0.0012	0.08	13.9	2.9	1	23	194	217	194	217	0.96
3	12	0.03	2	9.5	1.2	2	23	224	245	223	245	0.86
4	12	1.6e-05	0.001	19.8	3.1	1	23	251	273	251	273	0.98
5	12	5.8e-05	0.0038	18.1	0.8	2	23	281	303	280	303	0.96
6	12	8.4e-06	0.00055	20.7	1.2	1	23	309	331	309	331	0.99
7	12	0.00021	0.014	16.3	4.2	1	23	337	359	337	359	0.98
8	12	9e-05	0.0059	17.5	1.5	1	23	365	387	365	387	0.99
9	12	0.0022	0.14	13.1	3.7	2	23	394	415	393	415	0.94
10	12	0.0042	0.28	12.2	6.7	1	23	421	444	421	444	0.96
11	12	0.013	0.87	10.6	0.4	1	23	479	502	479	502	0.94
12	12	0.00068	0.045	14.7	4.8	1	23	508	531	508	531	0.96

Sequence Information

Coding Sequence: ATGAGTGAAATATGGAATTTGAGTTCTGTATGTCGTTGTTGCCATTCTGATGGAGTATTTAGAAATCTTGATACTCCTTATGTAGTAGAAAATAATGTTGAAATTTATTCGATAATGTTACGCCAAACTTTGGGCATTAACATATTCATGCCAGCTATTGAAGTGAGTAAAACTATTTGTGAAGAATGTGTACAGAAACTACGGGATGCATTCTACTTTAAAAACCAAGTAGTAGCATGTGAACAGAAGTTTGAGGAGTACTGCAAaaATGAACAGGCCTTAAATGAAAATGTGGAAACTATCAAAACAGAATTAGACACAGCTGATAATGAAGACAAATTAGCAAATGGGGTGTTAAAAACTGAATCTTTATGTAAACAATCTCAAAAAGAGACtcctagaaaaaatattattaaaggCGGAAAAGTAAAAAACCCGACGTTAAAATATGAGTCGTTAGCGAAATTAAGGCGCGCTCGGAAAAGGAGAAGCGAATATTCATGCCAGCTCTGTCCAGCTACGTACAGCACCAGGGAAGCTCTTAGAGCGCACATAGATCAAATGAAACATGAAATGATTTACAAATGCGAGgTCTGTAGCCAAAAGTTTACGTCTAAATCTCAACACAACAGACACTTAGCATCGGTACACAGTGACATCAAACCATTGAAATGCAAACATTGCCCAAGAACCTTTCGACTAGAAACCTCGCTTCCAGAACATGAGAATCTTCATACCAAACAAAATCTATATCAATGCGATATCTGCAACAAGATGTTGAAGCACAAGCAGACACTGAAGAAACATATCCAGTGGCATTTAGGACTGCAGAGGAAGTTAATATGTGAATTGTGTGGTGGAACATTTAATGACCAGTGCAATCTACGGAAACACGTGCAAACTGTTCATCAGAAGTTGAAGCTTTACAAATGTCACCTATGCCCAAAGGAGTTTGCTGCAAATAAAGGCCTGAAAGTTCATATGCGGCAACACACCGGCGAAAGACCGTTCTCTTGCGACATCTGTGGCAAGAGCTTCACGTCGTATTCCACCTGTAAATCCCATATATTCACACACGATCCCAAATTCAGGTACAAATGCAAAGTTTGTACAGAAACATTCGAAAAGCGAGGGGCATTCGCGAAACATACTAAAATGCACGTGGGCATGAAGCCACTAGTCTGTCATATTTGTGGACAAGACTTCACGTGCAAATATTCTTTGAAGAGGCATATCTTCGAACACACCGGGGTGAAACCATTCGTATGTGACAAGTGCGATTGTAGATTCTCTCAAAAATGTGGGTTAATCAGACACAACAAAAGGTTCCATAGCGGCACTGTCCGTTCACCAGCCGATAGGAAACAATGTGGTTTATGTAAACGACTTGTTTACAATATTGAGAAGCATTTACAAACTCATAATAATAGGCCACACGTGTGTGAATATTGCAATAAGACATATGCGGCTAGGAATATATTGAATCGTCACGTTTTGAGCGTACATTTAGGACTAAAGTCGTTTAATTGTCAGTTTTGTGATAAGAAATACAAACAGAGGAATGCATTAAAGCACCATTATCTGAAAGCCCACAAGATGCCATTGAAAACGGAATTAGAAGAAAATATGGATAGTGTGGTCACTAAATATACAATTGCCAATAAATATAGGAAAAAGAAAATTTGTGTTAATAATTTAACTGTGGATATGCCATTGATAGAAGAGTCTGATAAAAAGTAA
Protein Sequence: MSEIWNLSSVCRCCHSDGVFRNLDTPYVVENNVEIYSIMLRQTLGINIFMPAIEVSKTICEECVQKLRDAFYFKNQVVACEQKFEEYCKNEQALNENVETIKTELDTADNEDKLANGVLKTESLCKQSQKETPRKNIIKGGKVKNPTLKYESLAKLRRARKRRSEYSCQLCPATYSTREALRAHIDQMKHEMIYKCEVCSQKFTSKSQHNRHLASVHSDIKPLKCKHCPRTFRLETSLPEHENLHTKQNLYQCDICNKMLKHKQTLKKHIQWHLGLQRKLICELCGGTFNDQCNLRKHVQTVHQKLKLYKCHLCPKEFAANKGLKVHMRQHTGERPFSCDICGKSFTSYSTCKSHIFTHDPKFRYKCKVCTETFEKRGAFAKHTKMHVGMKPLVCHICGQDFTCKYSLKRHIFEHTGVKPFVCDKCDCRFSQKCGLIRHNKRFHSGTVRSPADRKQCGLCKRLVYNIEKHLQTHNNRPHVCEYCNKTYAARNILNRHVLSVHLGLKSFNCQFCDKKYKQRNALKHHYLKAHKMPLKTELEENMDSVVTKYTIANKYRKKKICVNNLTVDMPLIEESDKK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -