Gmel018485.1
Basic Information
- Insect
- Galleria mellonella
- Gene Symbol
- ZNF212
- Assembly
- GCA_958496185.1
- Location
- OY292304.1:5332795-5339608[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 0.002 0.13 13.2 1.0 2 23 59 80 58 80 0.95 2 12 0.015 0.97 10.5 2.5 2 23 87 109 86 109 0.95 3 12 3.4 2.2e+02 3.0 0.2 2 23 117 139 116 139 0.88 4 12 0.00024 0.016 16.1 6.2 1 23 145 167 145 167 0.96 5 12 1.3e-06 8.4e-05 23.3 5.4 1 23 173 195 173 195 0.96 6 12 0.0031 0.2 12.6 1.7 1 21 201 221 201 222 0.94 7 12 0.095 6.2 7.9 1.2 3 19 243 259 242 264 0.92 8 12 7.4e-05 0.0048 17.7 1.0 1 23 557 579 557 579 0.96 9 12 0.0014 0.09 13.7 0.2 1 22 585 606 585 608 0.89 10 12 0.0011 0.073 14.0 1.5 1 23 616 639 616 639 0.95 11 12 3.4e-05 0.0023 18.8 1.7 1 23 645 669 645 669 0.96 12 12 4.4e-05 0.0029 18.4 1.3 1 22 675 696 675 696 0.96
Sequence Information
- Coding Sequence
- ATGGAGGCCAATTTACCTTTTTACAGTGTGCTATGTGCGGATGGGGAGTCTTCTGAATTGCAACATGGCCTTCAGGCCAGTGGGTCACTTTTGGGCACAGATGATGTCTTGGCGCAGTTGTTACCAGGAGATGAGCCTTTGGAAGAGCCAGACTTAAACGGGCCGACAACTTTACACTGTGAAATTTGTGGGAAGCGGTTTGACAATGCAACAAAATATTATGGACACCTGAAGGCACATTCTAAAGGAAATCAGTGGGTTTGTGATAAGTGCCCCAACCAAAAGTTCTCAACTAAACAACACCTCATGAAGCATAGTCTGACCCATAAACCTTTGGAGAGGGTGTGGAAGTGTCTGCAGTGTTCAATGGCTTTCGAAGCTCTCTGGAGACTTCAGCAACATCTGTTTGCAAAACACCTTGGTTATAGACCACATAAATGTGACAAATGTGATAAATCATTCCACAAACTGTCTGATTTAAAAAAGCATAAAGATGTACATGATAatatcAAGAGGCATGCATGTAAGTACTGTGATATGCATTTCAAAGATAAGTCCAACTTGAAACGCCATATACTCACTCACACTAATGAAAAACCATACTGCTGTCCAGGATGTGGAAATAAGTTTAAACAGTTGGCATCACAAAAACGTCACCTGCAGAAGTGTGCATTAAACAAGTACATCAATGTGGAACCAACCAACAGTGCTACTAGGAAGAATTACTGTCGTGTTTGCGGTATGGCATTTCAATATAAAAGCAGTTTATTGGAACATTGTGTTCGGCAACATAGTAACACAGCAAGTGAGTTACCTAAACAAGAGAAAGTATCCATAATAAACACAGATGCAAATGGAACAGATGACAATATTGTAGATGACATCCTATCCGCTGAGGATGACTATATGAGAATGTCTTCACAAAACATGTATAATAATCAAAATGATGTTGACATCAATGCTGATAACCAAATGCAGATAGAGTTCCTCAAAGAAATGAATCAGTTGCGCATATTGGATGACGAGTTATTCTACAATGACATAGACATTGATAGTTTTCAAAGTAATCAAATATTCAATATGAACATGAGTCTTGTGGATTATGGTGCTAATGATAAGAATGGAGAGGTGCTGTTTGATTACATAGAAAGTGGTAGAAGTATAGACCAAGATTTAATGAATGCATTCTACCAAGTTAAAGAACATTTACCAGATGAATTTTTGAATGCAACTGACACAAATATGTTTCCCAGTAAAAGTGATTTACCAGTGAATCCTGCTGTTTCTGTTAACGAATGTGCAACTATATTTGAGAGTGATGTGGATCTAGAAGCAAGCACTAATCTAGCGGCAAATTTGAATCaattaataggtgaaaataatgtacaatatatatcaaCAGAGGATGATGAcacttttataataagtttgaaCAGTGAAGTGGATGCTGAGCAGTTAACTGATATGCTGAACATTGGTGTGGAACTTGATGGtgacaataataatagtgaAGCAGAAACAACTACAGACTTCACAATTAAAGAGGAAAAACCAATTGTGGTCAAAATAGAAGAACCCAATATAACCACTGAAGCTGCTGCAGTGACTGTAAAAAGTGACAaggtagataataaaaaaaccaaAGCCAAAGGGAAGAAGTGGATGTTGTTTGTATGTGGGacatgtaacaaaatatttaataagaaagaCAACTATAAGTCACATTTGGCGCTGCacggcggcgcgcggcggcaCGTGTGCGGCGTGTGCGGCGCGCGGTTCGGCTACCGCTCCACGCTCACCAAGCACGAGGCCGCCGCCCACCGGCCGCGAGTGCTGCCCGCGCACCCTTGCCAGCGTTGCGGCCGCCACTTCAGCGCCAACTGGATGCTGAAAGTGCACATAGAGCGTGACCACGAGAAACTAACACCACACGTCTGTGATGTAAAGGACTGTGGTAGGAAATTTTACAAGAAATCGGATCTCGTCGTCCACCAaagGTACCACACGGGCGAGCGTCCGTACTCTTGCGAGATCTGCCGCGCTTCGTTCCCGCACGTGTCGCACCTCCGCCGACACCAGCGCTCCGTCGACTGCACTAAGCAGTGA
- Protein Sequence
- MEANLPFYSVLCADGESSELQHGLQASGSLLGTDDVLAQLLPGDEPLEEPDLNGPTTLHCEICGKRFDNATKYYGHLKAHSKGNQWVCDKCPNQKFSTKQHLMKHSLTHKPLERVWKCLQCSMAFEALWRLQQHLFAKHLGYRPHKCDKCDKSFHKLSDLKKHKDVHDNIKRHACKYCDMHFKDKSNLKRHILTHTNEKPYCCPGCGNKFKQLASQKRHLQKCALNKYINVEPTNSATRKNYCRVCGMAFQYKSSLLEHCVRQHSNTASELPKQEKVSIINTDANGTDDNIVDDILSAEDDYMRMSSQNMYNNQNDVDINADNQMQIEFLKEMNQLRILDDELFYNDIDIDSFQSNQIFNMNMSLVDYGANDKNGEVLFDYIESGRSIDQDLMNAFYQVKEHLPDEFLNATDTNMFPSKSDLPVNPAVSVNECATIFESDVDLEASTNLAANLNQLIGENNVQYISTEDDDTFIISLNSEVDAEQLTDMLNIGVELDGDNNNSEAETTTDFTIKEEKPIVVKIEEPNITTEAAAVTVKSDKVDNKKTKAKGKKWMLFVCGTCNKIFNKKDNYKSHLALHGGARRHVCGVCGARFGYRSTLTKHEAAAHRPRVLPAHPCQRCGRHFSANWMLKVHIERDHEKLTPHVCDVKDCGRKFYKKSDLVVHQRYHTGERPYSCEICRASFPHVSHLRRHQRSVDCTKQ
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -