Basic Information

Insect: Galleria mellonella
Gene Symbol: znf423
Assembly: GCA_958496185.1
Location: OY292294.1:3684335-3694604[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 6.9 4.5e+02 2.1 0.1 1 23 89 112 89 112 0.89

2 18 1.5 95 4.2 0.2 3 23 117 137 115 137 0.95

3 18 0.046 3 8.9 0.1 2 23 141 163 140 163 0.94

4 18 0.013 0.82 10.7 0.1 1 20 425 444 425 446 0.95

5 18 0.008 0.52 11.3 0.5 2 23 456 477 455 477 0.92

6 18 4.8 3.2e+02 2.6 2.5 1 23 493 516 493 521 0.86

7 18 0.021 1.4 10.0 1.7 1 23 525 548 525 548 0.95

8 18 2.8 1.8e+02 3.3 1.1 8 23 599 615 591 615 0.88

9 18 0.26 17 6.5 0.5 2 23 626 648 626 648 0.84

10 18 6.1e-05 0.004 18.0 1.8 1 23 682 704 682 704 0.96

11 18 6.9e-06 0.00045 21.0 1.0 1 23 711 733 711 733 0.98

12 18 0.0001 0.0067 17.3 2.3 1 23 738 760 738 760 0.96

13 18 0.00043 0.028 15.3 1.5 1 23 766 788 766 788 0.98

14 18 2.1e-06 0.00014 22.6 1.4 1 23 794 816 794 816 0.98

15 18 9.6e-06 0.00063 20.5 1.8 2 23 823 844 823 844 0.98

16 18 0.00071 0.047 14.6 0.7 2 23 852 874 851 874 0.97

17 18 5.7e-05 0.0037 18.1 0.7 1 23 879 901 879 901 0.98

18 18 0.00059 0.039 14.9 1.1 1 23 907 930 907 930 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	6.9	4.5e+02	2.1	0.1	1	23	89	112	89	112	0.89
2	18	1.5	95	4.2	0.2	3	23	117	137	115	137	0.95
3	18	0.046	3	8.9	0.1	2	23	141	163	140	163	0.94
4	18	0.013	0.82	10.7	0.1	1	20	425	444	425	446	0.95
5	18	0.008	0.52	11.3	0.5	2	23	456	477	455	477	0.92
6	18	4.8	3.2e+02	2.6	2.5	1	23	493	516	493	521	0.86
7	18	0.021	1.4	10.0	1.7	1	23	525	548	525	548	0.95
8	18	2.8	1.8e+02	3.3	1.1	8	23	599	615	591	615	0.88
9	18	0.26	17	6.5	0.5	2	23	626	648	626	648	0.84
10	18	6.1e-05	0.004	18.0	1.8	1	23	682	704	682	704	0.96
11	18	6.9e-06	0.00045	21.0	1.0	1	23	711	733	711	733	0.98
12	18	0.0001	0.0067	17.3	2.3	1	23	738	760	738	760	0.96
13	18	0.00043	0.028	15.3	1.5	1	23	766	788	766	788	0.98
14	18	2.1e-06	0.00014	22.6	1.4	1	23	794	816	794	816	0.98
15	18	9.6e-06	0.00063	20.5	1.8	2	23	823	844	823	844	0.98
16	18	0.00071	0.047	14.6	0.7	2	23	852	874	851	874	0.97
17	18	5.7e-05	0.0037	18.1	0.7	1	23	879	901	879	901	0.98
18	18	0.00059	0.039	14.9	1.1	1	23	907	930	907	930	0.98

Sequence Information

Coding Sequence: ATGACCTCCGACGAATCAGACGATGAACCATTATCAGTGTTAGCGGCGGCGAAAAAGTCTAATCCAGATCAATTTGAGACTAGATCATCTGACGAGGACTATGAAccaaagaaaaagaagaagaaaaagtcaatttataaaatagagtCCAAAAAAGCTTCTAtcacaattaaattacaaaaaaagagaGTGTTAACTCCAAAAGTTATAGAAAGACCAACAGATGTTTGGCTATATATGAAAGATTTAAATCCGACGGGCCCATATAGTTGTTTGCTATGTCCTGAATGGTTTATAAACAGGGCTAAAATGATTATTCACTACGTACTTAATCATAAAAAGGATTTCTGTGGTATTTGTAGgTACTTTGTACCAGATCGTGAAACCTGGTGGACCCATCTGAAATTCCATATTCCTTGGCCATGTTCTCAGTGTGTTGAGAATTTTCAAACTGAGGGGGCACTCCGTCAACACCTTAGCAGTGCTCATAAGCTGGTCCACTGTCGTCTTTGTCACTTTAGGGTCTCTGATGATGATCAATACAAAACACATCTCTTTCAAAAACACAATGTCACTAATGTATCTAATATAAGTTGTGAAAATTTATGGGAACTAGATTATGAAAGTGGCACTAAATTCCTCTGCCTGCTGTGCTCAAAAGCAAACAACTTATCAACAACTTTCTTCAATCATTATATGGGATTCCATCATTTTACTTTGAAATGTTTCACAAACATCATATCTGGTAGAGATCCACCATTCTCTGTGTTTGGCGCTGATGTCAGCTCTCAATTTATCGATGGTCAGTTAAAGAACCAAGTTCGATTTGGTTACATAGATTTGGAGAAGAAATGTATAGACACTAAAGAAGGTGAGACCAGAGGGGGATCTCAAGTGCTTAATGTCCTTATTCCTGAAATTAAACAAGAAAGTACTGGTGACACTAATGGTCAATATAAACAGGAGGACAAGGAAAGTGAAGAAATAAGAAAGAGAGATGATGAAATTGTGAAGACATACATGGGTGATGAAGATTTCGATGTGACATTAATGGAactgatattattagaaaagtGTTACTTTGATTATGTGAATCAAACTTTAGaagatataaattcaaatactgTACCAATAGGGTCGGATATAAATTATCGAGTAACAAAAACAGATGCGGAGCCTGAAGTGAATTGTGCAGTATGCAATACAAAGTTACCAGTACAGGAATATCCAGGACATGTGGGGAAAATGCACAGTGTAAAATCAGTACCTACATTTTCGTGCCGAGTGTGTGCTACTACATTTAACAGTCAGACTGAACTTGAAACACATGTGGCAGAGGAATTGGCGGATTTTGATGACTTATGGATTTGCCAGTTTTGTGACAAAGAGTTTGATAATAGAGAATCAACTAGGAGACATTTGGTAGAACATTTAGATATCATGGAATATGACAATTGTTTTAGCCCACATCTAGGTTTCAAATGCAAGTACTGTCCCACATTATTTTGGAACGAGACAGACAGAGAGACACACCAAGTCCGTGTGCATTTGAACAAGCATCAAGatcaatattacaaatgtgaaagttgttCAGAAATGTATAGTGACAAGgTTTGGTTCATTCATCACTATTTGGAAAAACATCAGAATCCCGAAGCAGCTACACCGTCTTACTTGTTGAAGTGCTGCATCTGCTGTCTGGTGATGACCACCATTGAGGAAATGAGAGAACACTTCCAGAGCAGTCATCCTGAGGCTAGGAAGGTGTTCTGCTCCTTGGATTCATGCCAGTATAAACCACTTAGTCACAGGAAATCATTCAAGTTACACATAAGAACGGTGCACACGGTGGGCGGGCGGCCCGAGCGGCCGGCGCGGTGCTCGGTGTGCGGCCGCGAGTTCCCGAGCGCGCGCGCCTGCAACACGCACGTGGCGCAGGCGCACGGGCCCGGCAAGTACAAGTGCAAGCTCTGCAGGGACGTCATGCACACCATGGACGAgagAAAACTTCACTACCTACTCCGCCACCCTGGTCGGCATCCGTTCGAATGTTCGGAATGTGGTAAATCATTCCAATACAAGTCCTCGCTGTATATGCACAAGCAGGACCACGCGCCGAATAAACAGACGTATACCTGTGACTACTGCGGAAAGGTGTTTATGAAGAAGGACTCGTTCCGCGAGCACGTGCAGATCCACGAGGGCCCGCGGCACGCGTGCTCGTACTGCCCGATGCGGTTCGTGCAGCGCTCCAACATGCTGCGCCACGAGCGCCGCCACACCGGCGAGCGGCCCTACGCCTGCCCGCACTGCCCGCGCACCTTCGCCGACAAGGGCGCCTGCACCTCGCACGCCAGaaCTCATTCAAAAGATACTTCGTATGCTTGCCTGTACTGCGGTCAGACGTTTGTTCAGAAGTCGAAACTCACGTATCATATAAGAAAACACACGGGAGAAAATTTGGAAACTTGTCCGATATGTTCGAAAATGTTTACAAGCGCATGCTCGCTTCGTGAACATATGAAGATCCATCAAGCTAGGAAAGGATCTGTTAAATGCCCGTTGTGTGAAAAAACGTACCAAGATGAAAGATATATGCTGCGTCACCTGCGCACGACGCACACGCGGTCGCATTTCTCCTGTCCCATCTGCAACAAGTCTCTCAGCAGCACGGCCGGCCTGCGGCACCACGTGCTCACACACAGCTCCATCAATACGTATAGATGTAAAGTTTGCCCCAAATCGTATGCCGTCAGAAGAACGATTGTGAAACACCTTCGTAAACGTCACGGGATCAAAGACACTGCTGTGAATATAAAGGACTTTTACAAGAAAATGGATCCGAGAGAGTGTGAATTGGGCCTGGACGAGGAAGTCATGACTAATATATTTGGACCACCAAAGAAAATCGTCAAAGATATTTTAATGGGAAATTTTGTTACCATAGCTAAAGACTTTAATTTACCCAAAGAAAGTTCAAAAACTAACACGAATAATGATGATGGCGATGGCGATGGTGATGACGgcgataatgatgatgatgatgatggtgacgGCGACAACGATGATTCCGATGATGGTAAAGATGAAGAGAAATCCAAAGATGGCGATGGAGGTGCTAGTAATgagtttgtaaaaaataagacaataaaGCAAGAGCCAAGTGATAATGAAGAGTTGGAGCCAACTGACTTTGTGAGTGTGAAGATCGAACACATGGATGAAAACACAGATGAGGAAACTTAA
Protein Sequence: MTSDESDDEPLSVLAAAKKSNPDQFETRSSDEDYEPKKKKKKKSIYKIESKKASITIKLQKKRVLTPKVIERPTDVWLYMKDLNPTGPYSCLLCPEWFINRAKMIIHYVLNHKKDFCGICRYFVPDRETWWTHLKFHIPWPCSQCVENFQTEGALRQHLSSAHKLVHCRLCHFRVSDDDQYKTHLFQKHNVTNVSNISCENLWELDYESGTKFLCLLCSKANNLSTTFFNHYMGFHHFTLKCFTNIISGRDPPFSVFGADVSSQFIDGQLKNQVRFGYIDLEKKCIDTKEGETRGGSQVLNVLIPEIKQESTGDTNGQYKQEDKESEEIRKRDDEIVKTYMGDEDFDVTLMELILLEKCYFDYVNQTLEDINSNTVPIGSDINYRVTKTDAEPEVNCAVCNTKLPVQEYPGHVGKMHSVKSVPTFSCRVCATTFNSQTELETHVAEELADFDDLWICQFCDKEFDNRESTRRHLVEHLDIMEYDNCFSPHLGFKCKYCPTLFWNETDRETHQVRVHLNKHQDQYYKCESCSEMYSDKVWFIHHYLEKHQNPEAATPSYLLKCCICCLVMTTIEEMREHFQSSHPEARKVFCSLDSCQYKPLSHRKSFKLHIRTVHTVGGRPERPARCSVCGREFPSARACNTHVAQAHGPGKYKCKLCRDVMHTMDERKLHYLLRHPGRHPFECSECGKSFQYKSSLYMHKQDHAPNKQTYTCDYCGKVFMKKDSFREHVQIHEGPRHACSYCPMRFVQRSNMLRHERRHTGERPYACPHCPRTFADKGACTSHARTHSKDTSYACLYCGQTFVQKSKLTYHIRKHTGENLETCPICSKMFTSACSLREHMKIHQARKGSVKCPLCEKTYQDERYMLRHLRTTHTRSHFSCPICNKSLSSTAGLRHHVLTHSSINTYRCKVCPKSYAVRRTIVKHLRKRHGIKDTAVNIKDFYKKMDPRECELGLDEEVMTNIFGPPKKIVKDILMGNFVTIAKDFNLPKESSKTNTNNDDGDGDGDDGDNDDDDDGDGDNDDSDDGKDEEKSKDGDGGASNEFVKNKTIKQEPSDNEELEPTDFVSVKIEHMDENTDEET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -