Gmel004125.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Galleria mellonella
Gene Symbol
-
Assembly
GCA_958496185.1
Location
OY292285.1:15714521-15725611[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 8.7e-05 0.0057 17.5 2.6 1 23 195 217 195 217 0.99
2 29 0.00025 0.016 16.1 0.5 2 21 249 268 248 269 0.92
3 29 8.1e-06 0.00053 20.7 0.5 3 23 307 328 305 328 0.96
4 29 0.017 1.1 10.3 0.7 1 23 381 404 381 404 0.97
5 29 0.0054 0.35 11.9 0.2 1 23 426 448 426 448 0.97
6 29 0.00014 0.0091 16.9 1.4 2 23 488 509 487 509 0.95
7 29 0.00068 0.044 14.7 2.2 2 23 556 578 556 578 0.97
8 29 0.0057 0.37 11.8 0.3 1 23 628 653 628 653 0.96
9 29 0.00067 0.044 14.7 0.1 1 23 718 740 718 740 0.98
10 29 0.036 2.4 9.3 6.0 2 23 752 773 751 773 0.96
11 29 0.097 6.4 7.9 1.8 2 23 785 806 784 806 0.96
12 29 0.0038 0.25 12.3 1.0 1 23 816 838 816 838 0.98
13 29 0.043 2.8 9.0 7.4 1 23 867 889 867 889 0.96
14 29 0.00069 0.045 14.7 1.9 1 23 900 922 900 922 0.98
15 29 5.3e-05 0.0035 18.2 0.4 1 23 930 952 930 952 0.98
16 29 0.0034 0.22 12.5 0.1 2 23 972 994 971 994 0.97
17 29 0.057 3.7 8.6 1.0 1 23 1012 1034 1012 1034 0.94
18 29 0.14 8.9 7.4 3.7 1 23 1041 1063 1041 1063 0.97
19 29 0.0098 0.64 11.0 2.5 2 23 1074 1096 1073 1096 0.95
20 29 0.00068 0.045 14.7 0.5 1 23 1118 1140 1118 1140 0.97
21 29 0.4 26 6.0 0.6 2 20 1144 1162 1143 1164 0.92
22 29 0.0018 0.12 13.3 0.2 2 23 1221 1242 1220 1242 0.95
23 29 0.1 6.6 7.9 3.2 3 23 1250 1270 1248 1270 0.96
24 29 0.017 1.1 10.3 0.9 2 23 1281 1303 1280 1303 0.95
25 29 0.25 16 6.6 2.9 2 23 1320 1338 1320 1338 0.91
26 29 0.29 19 6.4 1.0 2 21 1342 1361 1342 1362 0.92
27 29 0.82 53 5.0 0.9 2 23 1411 1432 1410 1432 0.93
28 29 0.0052 0.34 11.9 0.8 2 23 1443 1465 1442 1465 0.96
29 29 0.15 9.7 7.3 3.7 2 20 1503 1521 1502 1523 0.93

Sequence Information

Coding Sequence
ATGGCCCTCAAATTGGGAAAGTGCAGACTTTGTCTGAAGCTTGGGGATTTCTACTCCATCTTCACCGTCGACAATGCTGTTCAGTTGGCCGAGATGGTGATGGAATGTGCGCGGATTAAAGTGTTCGAAGGCGATGGGTTACCAGACAAGATTTGTTCTGAATGTATCCAGAAGTTAAGCAGCGCCTATATATTCAAACAACAGTGCGAAAGATCAGATCAAGAACTACGACGGAACTATGTCCCACCGCCCGGTTTCAGTGACACCCCTCCATCGACCAACAGACAAAGCAGTGACTCTGCATTTTCTGGACACACCGAACACTCTGGCCAAGTCAAACCGTCTTCATCAACCGATAGCAAAACAACGCCCAATCGCAAGCGAAGTCACGGCAGTATCGACAATGTTTCGGTCACAAGTCGGTCGCACGACAGACCCAGTAGCACCAAACGGGTCGAAGAACTCAGGAAATCGCAGAAAAGAGCTAGGCTCAATTCAGAGAATACCGATTCAGATTTCGATTACAGTGCCTCGCAGTTCTCGGCCGAAACTGACTCTGATGAGCCCTTGTTAAGGACAGACTACAAGTGTGAAAAATGTGACAGgtcatttaaatcggttaaaagtCGCTCTGCACATATGAAAACACATTCCGGTGGAAAAGCATCTCTCGGTGAAAATGCAGTAGTCAACATCCCAAAGAAGAAGGTTTTGGAGGACGCTATGGACTCGGATAGTAAATTGAATTGTGAAAAGTGTGGGAAAACATTCAAATTGAAGATTATGCTGAAGCGGCATTTAGAGACATGTGAGACTAGTCCCCACAAGATACTAATGGAGAAATTAGACAAGTCACCGCAGAAAGAACTGTTAGTGTCGTTACAACCGATCGACATGTTACAGGCACGGAGGCTCGACTGTGAAATATGCACGACGAAATTTAAAACTATAGACAATTTACGCAAACACATGCGCGTGGTCCACGCCGCTGTACTCAAAAGGGATCGCGCCGAGCCAAAAGAAGAGAAAGAAAACGGACTAACCACTGTTCCTTGTTTATTTTGTCAGAAGCCCTTTCAAGATTACTATGGGCACAGTGAGCATTTTTTGAAATGTCCACAAAAGAGAAGTTTAGAAAGTTACAGTTGCCCCATATGCCATAAAGTGTTATCAAAAATCAATGTATATATTCTTCATATGAAAAGCATGCACTTTGGAGAACGGCTATTGGATGAACCAATGGATGAATCGACTTCAACGCCTAAGGCAGAGTTTTTTGAATGTCGCATGTGTAGTAAGAGATTAGCGAGCCAAGAGTTGCTTATTACACATTTAGCAAGTCACATGTCCAATATGGATAACAATGCTGCTGTGGATGATGACTCAAGAGCAAGTACACCAATTGACTCGATATCTGTCAATTCATCGTACAGCAACACATATGGACCAAAAGGAACACTGAATTGCTCACAATGTGACAAGTcgtttaaatacaaaaaagctCTCGAAACCCACGAATTAAAACACTCAACTGGAGAGATAGATATAAAAGTGGAGCCGCCAGATAAGTCAGCATCGACAAGCCTTTTGTCCGAGTCACAGCTACAACTGCCGCGAGCTGAGAATTCAGAGTCAGAGTCTAGTCATGATGAAGCCGAGGATAATACGTGTGATATCTGCGAGAAGCAGTTCTCGTATAGACGCTTGTTACTGCAACACAAGCGTACCAAGCATAATATGAGTTCGGGCACAAAGCGAGCGAAGATCACCTTAAAGGACTGCATGGTCCGTTGCTTGATATGCGACATCGAGATGAAAGTGAGCGCAATCAACGAGCACAACCAGAAGCACATAACTGTAAACATCAAGCCAAGAAATATGTACACGTGTGGAGTGGTCGAGTGTGCGGAGAAGTTCAAGAGTTGCAGTGCACTAGCGAATCACATAAAACTAATACACAGGTTGAAACAGCAGCCTAAACAGTCACAGAAGCTCCCGAGGCTAGAGGGTGGGTCGGATCTGGCGGATTTTTGCGAAGTCGTTGTGACTAAAACGGAACCCCTGGACACGCTCCAGAGTCACAACGGCTTTGGAGAGGTTCCAGTTACAAATGGCGAACAGGCGGCCGGACCCCTGGTCAATATGAGTGGGTTCACATGCACGATATGCGGGAAGGTGATGGGCACGCTCATATCATTGAAGAGACACATCAACTGGCATACCAATGTTGGGAACAATATAGAGAAAATGATAGAATGTTTTGTTTGTAAGGAGAAATTCCGCTTCCAATGTCACTACAAACTGCACATGCGTGAACATTACCGAGACACAAATCTGGATCCCAAGTTCCTCACGTGCTCCATCTGTAATCGCAAGAGCAAGCATCTACGTGCCGCGCAAGCGCACATGAACTTCCACAAGCAAACGCGGTTCAAGAACAAAGACTATCAGTGTTCCATATGCAAGAGGGTGTTCCAGTATAGGAAGGTGTATCTATCACACATGGCCATCCATTACAAACGAGGTGAGAGCGTCCAGAACACTATTGTAGGTGATGTAGTACCAAATAATCTCGATAGAACTATTTTTGATGGTACACACACATGCCATCTTTGCAAGAAAGTTTGCGACTCTGAAACTTCCCTAAAACATCACATCATATGGCACAAATCGAAAACTTCGCTCTTTGGTGCTCGTCACGAGTGCTATGTTTGTCAATTAGTCTTCACAAATAAAAGGCGATTGGAACTACACATCAGAAGTCACTATGAAGATGAGAATGGACCGTACAAATGTCAAATTTGCGGTAAAGGCTACATAGACGAGGAGTACTTTAAAAGGCACGTAAAAGGTCACAACTTCGACCATCAATCGCACAAGAAGAGAATAGAAAAACTTAGGAAAGACAAAGTGAAATGTCCTATTTGCGCTCGTTACTACCCAGACTTGGTGAAGCTTATTCGCCACCTGAGGCGAACTCATCCAGAGAGCAAGATGATTAAAGAGGACCCTGATGCACCACCGCCCATTTATTATTCTTGCAAACTATGCGCAAAGGTATTCATGGATGAAAGAAGACTGCAACATCACGAGGAAGCTCATTTACGGAAACCAGAGTTCTTTAAGTGTAAATTCTGTGGTAAGAAAACTATATCCTTGAAAAACCATCGAATTCACATCAAGGGACACTTGTGTGAAAAACATTTGGACAATCCACTGCAGTGTCCTCATTGTGAGGAGACATTTATTAAAGGGTACGGTCTCCATCATCATTTGAGGGACGCCCACGGTATCAACGAAACTTGGATCGCCGACCGCAAGGAGCAAACCCTGGATGGACCACTGAAAGAATTCCAATGTTCTATTTGCTTTAAAATATTGGCCAGTAAAGGAAACTTTGAGCGGCATATCGACTACCATAACTCCTTAAGATGCAATTACTGTTTTGAATATTTCAGCACACTTCGATTCCTAGAAGGTCACTTATCATTTAGTTGCGATAAGAAAAAATTGATAGGGGATAGTGAGATCTATCCAAAGAAAGTGAAATGTCATGTTTGCTATAAGGCGTTCCATTTACAAGTGAAATTGGATTGTCACTTGCGAACACAACACAATATTAAAGTGAACAAGGAAGCATCTTCGGGCAGAAAAGACATAGTGTGTGACTACTGCTTCCGCGTATTCGAAAATGAAGACGCGTTAACCACACACAAACTGTACCACCGCACAATTGGCTACTACGGTTGCCTTTACTGTAAGAGAAAGTTCAATACAATGACTCTATATCGGAAGCATAAGAACTACCATTACTCGCAACTGAACGTGGACAATCCGACCAAGTGTGAACACTGTGACGAGACATTCGTGGCCTTCCGAGAAATGATATACCATATGCGGGATGAGCACGGCGACAATAAGGAATGGATAGTCATGCCCAAGGAGTCAATAGAAGAGAAATGTCCCATTTGCAACaagatattttacaatttacacaAACATCTAACTTACCACGAGGAGAACAGGTGCAAAAAGTGCGGTGAATACTTCTACTCGAGGATAGACTATGATAATCATTTGTGCGCCATCGAAAGCGACGATGATGGTGTGGAAATCGTCGACGGTACGTTCCAACCGAAATACGAAGAGTGCAGGTTCTGCTTTAAACCTGTTACAAGGAAGAATAGCAAGCGACTCCACAATCAGATACACCAAGTATCCGGCGCCATCTCTTGTCGGTTCTGCACGTTGAAGTTCAAGACAATGGAAGCGTTCAACATCCACGCGTTCTCGCACAGAAGTCGAAAGTACAACAAGAAACCCATAAAGTGTAGAAAGTGTGGCGAAAAGTTCGTCAAGTACGgtgtatttattaaacacatGAAAAATGAACACAAGTCCTTGAAGAAAATGCATTATCGAGCAGTAGTGAAGGCGGAACGATGCGTCGTGTGTGGCGATGACTTTCCGAACCTACACAACCACTACCGCGCACACCTGCAGAACCAGTGTCACGGTTGCAATAAGTACTTTACTTCATATAAACTGTTCTCACAACACGAATGCGGCAAAGAGGACGCCGATCCGTCGAAAGTGTTCACTTGCGATGAGGATCTCGTCGCGCTCATCAATTCTTACATTCCAAAAGATGAGAAGGACGATGAGAAGTATTACGGGTACAATGATGACGAAGAAGAAGGAGAGGACGAGCCTTTTGAAGAGAATAAGTCCCAACACTCTCAACAGAGCGAACCGATTGATGATGAGCAGGAACATAAGAATGTTAAATTTTTCACCGAATCTCAAGACGAGGAGAGCCAAGACGAGAGAATATTGCATGATATGGTACAGTCGCCCATAATATCGGACGTTCTTTCACTGTATCAGAAAAAAGAAGACAATGATTGTGAAATAGTTAATTTAACAGATGATGACTCTATGGATGTGGATGTGAGTGTCCCTGTCATTACAATCGATGATGATTAA
Protein Sequence
MALKLGKCRLCLKLGDFYSIFTVDNAVQLAEMVMECARIKVFEGDGLPDKICSECIQKLSSAYIFKQQCERSDQELRRNYVPPPGFSDTPPSTNRQSSDSAFSGHTEHSGQVKPSSSTDSKTTPNRKRSHGSIDNVSVTSRSHDRPSSTKRVEELRKSQKRARLNSENTDSDFDYSASQFSAETDSDEPLLRTDYKCEKCDRSFKSVKSRSAHMKTHSGGKASLGENAVVNIPKKKVLEDAMDSDSKLNCEKCGKTFKLKIMLKRHLETCETSPHKILMEKLDKSPQKELLVSLQPIDMLQARRLDCEICTTKFKTIDNLRKHMRVVHAAVLKRDRAEPKEEKENGLTTVPCLFCQKPFQDYYGHSEHFLKCPQKRSLESYSCPICHKVLSKINVYILHMKSMHFGERLLDEPMDESTSTPKAEFFECRMCSKRLASQELLITHLASHMSNMDNNAAVDDDSRASTPIDSISVNSSYSNTYGPKGTLNCSQCDKSFKYKKALETHELKHSTGEIDIKVEPPDKSASTSLLSESQLQLPRAENSESESSHDEAEDNTCDICEKQFSYRRLLLQHKRTKHNMSSGTKRAKITLKDCMVRCLICDIEMKVSAINEHNQKHITVNIKPRNMYTCGVVECAEKFKSCSALANHIKLIHRLKQQPKQSQKLPRLEGGSDLADFCEVVVTKTEPLDTLQSHNGFGEVPVTNGEQAAGPLVNMSGFTCTICGKVMGTLISLKRHINWHTNVGNNIEKMIECFVCKEKFRFQCHYKLHMREHYRDTNLDPKFLTCSICNRKSKHLRAAQAHMNFHKQTRFKNKDYQCSICKRVFQYRKVYLSHMAIHYKRGESVQNTIVGDVVPNNLDRTIFDGTHTCHLCKKVCDSETSLKHHIIWHKSKTSLFGARHECYVCQLVFTNKRRLELHIRSHYEDENGPYKCQICGKGYIDEEYFKRHVKGHNFDHQSHKKRIEKLRKDKVKCPICARYYPDLVKLIRHLRRTHPESKMIKEDPDAPPPIYYSCKLCAKVFMDERRLQHHEEAHLRKPEFFKCKFCGKKTISLKNHRIHIKGHLCEKHLDNPLQCPHCEETFIKGYGLHHHLRDAHGINETWIADRKEQTLDGPLKEFQCSICFKILASKGNFERHIDYHNSLRCNYCFEYFSTLRFLEGHLSFSCDKKKLIGDSEIYPKKVKCHVCYKAFHLQVKLDCHLRTQHNIKVNKEASSGRKDIVCDYCFRVFENEDALTTHKLYHRTIGYYGCLYCKRKFNTMTLYRKHKNYHYSQLNVDNPTKCEHCDETFVAFREMIYHMRDEHGDNKEWIVMPKESIEEKCPICNKIFYNLHKHLTYHEENRCKKCGEYFYSRIDYDNHLCAIESDDDGVEIVDGTFQPKYEECRFCFKPVTRKNSKRLHNQIHQVSGAISCRFCTLKFKTMEAFNIHAFSHRSRKYNKKPIKCRKCGEKFVKYGVFIKHMKNEHKSLKKMHYRAVVKAERCVVCGDDFPNLHNHYRAHLQNQCHGCNKYFTSYKLFSQHECGKEDADPSKVFTCDEDLVALINSYIPKDEKDDEKYYGYNDDEEEGEDEPFEENKSQHSQQSEPIDDEQEHKNVKFFTESQDEESQDERILHDMVQSPIISDVLSLYQKKEDNDCEIVNLTDDDSMDVDVSVPVITIDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-