Basic Information

Insect: Galleria mellonella
Gene Symbol: -
Assembly: GCA_958496185.1
Location: OY292299.1:5387479-5391504[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00086 0.056 14.4 0.5 1 23 143 165 143 165 0.95

2 13 0.0032 0.21 12.6 4.8 2 23 172 193 171 193 0.96

3 13 0.021 1.4 10.0 7.6 1 23 199 221 199 221 0.99

4 13 7.2e-06 0.00047 20.9 1.7 1 23 242 264 242 264 0.98

5 13 4e-05 0.0026 18.6 2.6 2 23 272 293 271 293 0.96

6 13 1.2e-06 8e-05 23.3 1.7 1 23 299 321 299 321 0.99

7 13 2.7e-06 0.00018 22.2 3.1 1 23 327 349 327 349 0.96

8 13 7.3e-06 0.00048 20.9 2.6 3 23 357 377 355 377 0.96

9 13 2.2e-05 0.0015 19.4 0.2 1 23 383 405 383 405 0.96

10 13 0.00018 0.012 16.5 4.8 1 23 411 433 411 433 0.97

11 13 3.4e-06 0.00022 21.9 1.6 1 23 439 461 439 461 0.99

12 13 1e-06 6.8e-05 23.5 0.7 1 23 467 489 467 489 0.98

13 13 8.9e-05 0.0058 17.5 0.3 1 23 495 517 495 517 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00086	0.056	14.4	0.5	1	23	143	165	143	165	0.95
2	13	0.0032	0.21	12.6	4.8	2	23	172	193	171	193	0.96
3	13	0.021	1.4	10.0	7.6	1	23	199	221	199	221	0.99
4	13	7.2e-06	0.00047	20.9	1.7	1	23	242	264	242	264	0.98
5	13	4e-05	0.0026	18.6	2.6	2	23	272	293	271	293	0.96
6	13	1.2e-06	8e-05	23.3	1.7	1	23	299	321	299	321	0.99
7	13	2.7e-06	0.00018	22.2	3.1	1	23	327	349	327	349	0.96
8	13	7.3e-06	0.00048	20.9	2.6	3	23	357	377	355	377	0.96
9	13	2.2e-05	0.0015	19.4	0.2	1	23	383	405	383	405	0.96
10	13	0.00018	0.012	16.5	4.8	1	23	411	433	411	433	0.97
11	13	3.4e-06	0.00022	21.9	1.6	1	23	439	461	439	461	0.99
12	13	1e-06	6.8e-05	23.5	0.7	1	23	467	489	467	489	0.98
13	13	8.9e-05	0.0058	17.5	0.3	1	23	495	517	495	517	0.97

Sequence Information

Coding Sequence: ATGGATACTTTGTACATTGGGAACTTGGAAAATCGTTGTCGAACTTGCCTCAACAATACATCGAACAAAATGCATGATATTTTCGCTGAAAAAAGTGATTCTATTAACGCTGCTGAAATGCTGACGTCATGTACATCAATAGTGGTGAACCAGGATGATTCTTTACCAAAAATACTCTGTGGGAGTTGCTATAACTGCCTTGTTAGCTTCTATGACTTTAGAAAATTAGCTGAGAAGATAGATACACAACTAAGGCAACAATTGAGTAATATTACGTCTCTAGACGGTGAGAACGTAATGATTGAAATAAAAGTTGAAAACAATGTTCCTGACGCAGGCGCCGATTATGATTTACTAGACTGTGGAGATTTTGAAGTAATGAAACAGGAATTTGAAAGTCATAGTTCAGATGAAACATCAAAACCATTTTTGTGTGATATATGTTATCAATCATTCGATAGTTCTATTCAATTGGAAACACACAGTCAGACACACATAACAGACGCAAAACTCAAGTGTAACAAGTGCAATATGAGTTTTGACAAAAAAGCCAAGTTAGAACAACATAAACACAAACACAGCAAAAGCAAATTGTACACTTGTAGCTTCTGCTCGGAAACATTTAAGCATCATTTCAAGTATGTCAAACATCTGATCACGCATGGTGAAGATGTAAAAAGCAGGTCTTTTATGACAGAAATTAATCAGAATGAGAACCAACATTTCGAGTGTGGTGTGTGTTCCACAAGCTTTAAATCTACACATTCCCTTGCAGCACATATGcgtaaacatacaaaaaaagatAGGGTTTTATCCTGTTCTATATGTAGTaaggtatttaagaaaataagcCACTTGAAAAGACATGAGCTATCACATGAAAATAATAGACCATTTAAATGTACACAATGTTCAAAATCATTTATATCGGAAAGTCTTCTAACAGAACATATGAATAAGCACAATGGTGTGAAGCCACATGCATGCCCTATCTGCAGGAAGACATTTTCTCATTTGTCAACATTAACTTcacatattaaaattcatacacGGGAAAAACCACATTTATGTCCGACATGTGGGAAAAGGTTTGATTCTACCACTAACCTAAACCAGCATATAAAGAGGCATATTGGACTGAAGATGTTTGCTTGTAACTTGTGTCCTAGGACATTTGTAAGTAAAgGAGAGTTGAAATCACATGGTATAACTCACACTGGAGAGCGTTCCTACACATGTGATCAGTGTGGCTCATCATTTACTAAAAGGAGTTCACTTTGCAAACATAAGTTGAATCATTTAGGTGTAAAACCTTATCAGTGTGATGTTTGCCCTATGAAATTTGTGGGAAAAGAACATTTGAAACGGCACTATCGCATCCATACCGGCGAGAAACCGTACCGCTGTGATATGTGTGATCGTGCATTCACTCAGAGCAATGATTTGGTGAAACATCGTCGGGCACATTTAGGCGATAAGTTGTATAGgtGCGCTGAATGCACAGAAGGTTTTCGTCTTAAAAGCGAGTTGCGTCAACACATATCTGAACATTTCATATCTCGCCAACTTCAAGCGTTAACTGTCAATAAAGCGACTGAGGTTGACAGTGTATCCACAGTTGGTGAAATAGAACAAAGTACACCCAACATTATAGTGCATGGTAATGATATAACAGCTGACAACGAGAACATGGTAATTATCCAGAATGAATCTCTTTTGGTCGACGGTAATGAAAAGTGA
Protein Sequence: MDTLYIGNLENRCRTCLNNTSNKMHDIFAEKSDSINAAEMLTSCTSIVVNQDDSLPKILCGSCYNCLVSFYDFRKLAEKIDTQLRQQLSNITSLDGENVMIEIKVENNVPDAGADYDLLDCGDFEVMKQEFESHSSDETSKPFLCDICYQSFDSSIQLETHSQTHITDAKLKCNKCNMSFDKKAKLEQHKHKHSKSKLYTCSFCSETFKHHFKYVKHLITHGEDVKSRSFMTEINQNENQHFECGVCSTSFKSTHSLAAHMRKHTKKDRVLSCSICSKVFKKISHLKRHELSHENNRPFKCTQCSKSFISESLLTEHMNKHNGVKPHACPICRKTFSHLSTLTSHIKIHTREKPHLCPTCGKRFDSTTNLNQHIKRHIGLKMFACNLCPRTFVSKGELKSHGITHTGERSYTCDQCGSSFTKRSSLCKHKLNHLGVKPYQCDVCPMKFVGKEHLKRHYRIHTGEKPYRCDMCDRAFTQSNDLVKHRRAHLGDKLYRCAECTEGFRLKSELRQHISEHFISRQLQALTVNKATEVDSVSTVGEIEQSTPNIIVHGNDITADNENMVIIQNESLLVDGNEK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00008217;
90% Identity: -
80% Identity: -