Gmel021416.1
Basic Information
- Insect
- Galleria mellonella
- Gene Symbol
- -
- Assembly
- GCA_958496185.1
- Location
- OY292310.1:2369018-2374020[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 0.001 0.067 14.1 0.1 1 23 123 146 123 146 0.94 2 20 0.25 16 6.6 0.3 2 23 172 194 171 194 0.95 3 20 0.86 56 4.9 0.1 2 23 217 240 216 240 0.91 4 20 2.2e-05 0.0014 19.4 0.0 1 23 244 266 244 266 0.97 5 20 6.9e-06 0.00045 21.0 0.1 1 23 271 294 271 294 0.95 6 20 0.038 2.5 9.2 4.5 1 23 302 325 302 325 0.97 7 20 6.1e-05 0.004 18.0 0.8 3 23 334 355 332 355 0.94 8 20 0.00025 0.017 16.0 0.9 1 23 361 384 361 384 0.89 9 20 8.1e-07 5.3e-05 23.9 2.3 1 23 390 412 390 412 0.99 10 20 0.1 6.5 7.9 0.2 1 13 418 430 418 432 0.86 11 20 0.1 6.7 7.8 0.1 1 23 502 525 502 525 0.93 12 20 0.0034 0.22 12.5 0.0 2 23 552 574 551 574 0.95 13 20 0.059 3.9 8.6 1.2 2 23 597 618 596 618 0.97 14 20 0.014 0.95 10.5 0.3 1 20 622 641 622 644 0.93 15 20 0.0017 0.11 13.4 0.6 1 23 649 672 649 672 0.90 16 20 0.088 5.8 8.0 1.5 1 23 679 702 679 702 0.93 17 20 0.00077 0.05 14.5 2.1 1 23 708 731 708 731 0.96 18 20 0.00011 0.0072 17.2 1.1 1 23 737 759 737 759 0.98 19 20 5.2e-06 0.00034 21.4 1.4 1 23 765 787 765 787 0.99 20 20 0.00012 0.0075 17.1 4.3 1 23 793 816 793 816 0.98
Sequence Information
- Coding Sequence
- ATGCATTTGATTCCGGATAGATTatccaGTAAACGCCAGAAGCTCATCAGAATTGACGTTAAAGATGTCAATACAAAGGAAATAGTGGCAACACGAGAATTATCCTATGTAGATACAGACAAAGATGAAGATTACAttcttataattgaaaaatcaaATGACAGTGGTGATGAAAATCAAActgttaaaacatcttcaactgttaaagaaaatggaatggttaatacagacaaattaaaaacagtggtacagagtaataacaataGAAAGGAAGACGCCACCGcgaaatataaacatttgacAAATATAAAAGCTGTACTTGAGTATTCTAATGCGACTATTATTAGACATCGCGGTGGGATTGGTTACGTCTGCAGTTTTTGCCCCGAACAGTATCCTGATGCTGCAGATTTGAAGAGGCACACCTTGGAGAGGCACAATGACGTCAATCAGTGTTATATAAACAACATATCCATTTGTGATAACATAATCAAAGTAGATATCACGTCTCTTCGCTGCAAATTATGTGACAGTAATATCAAGTCATTGGAAGATCTTATGGAACATCTTCAGAATACACACGGGGTTAAAATATTCACCGACATAAAGAATCAAATGATACCATTAAAATTCGACACGAAAATCCTCACGTGTGCCATCTGCGACAACGGTGCGGTGTACAATAAATTCAAATCTCTTTTGGAACATATGAAAGTCCACTACAGAAACTATGTGTGCCAAGAATGCGACGCGGGCTTCATAAATCCTGCACAGTTGAGAGTTCACATGAACTTCCACGATATCGGAAACTACGCTTGTGAAATCTGTGGAAAAGTATTTACCAACGGTCGTACTTTGAAGGCACACGTGCGTGCTGTTCATATCATAAAATCGCAGCCCGCCTACAAATGTGGTTATTGTAATGAAAGTTTCCAATTCTTCCACAGCAAAGAGCGCCACTTGCAGAAAGTACACGGTGTTGTTATGGCTCCGATTAACTGTCAAGCTTGCGACAAATCTTTTACGACGCGTTCGACGTATTTAGCACATATGAAGTTAAACCATTTGATGATACGTCCTCACGCTTGTACGCAATGCAACAAGAGTTTTACTTACTCGGCTGCATTGAAAGAGCACGAGGGGAGAGTGCATATGGGATTGAAGCTGTATGAATGCGATTTGTGCAATAAACACTTTTCAACGAAGAACGCACTGCGACAGCACATACGTATTCATACAAATGATCGAAGGTACAAATGCCAGATTTGTGGGCAGGCGTTTGTAGCGAAGAGTAGTGGAGGTCAGGCTTACGCAACACGAGAGATTAATGAAGTTGAAACAAGGACTGGCGTAGTAAAACGTAAAGACGATCAAAATAAAGTAGATTTAAGAAAACGTAAAAGGAAAGACGACGCTTCTGTACTTAGAAAACATTATGTTAATATAAGAGAAATTCTTAAACATTCTAACGCTACTCCCATTCGAAGTCGCGGTGGTATTGGATACGCGTGTTCTTTTTGTACTGACCAATATCCGGATCCAGCAGACTTAAAGAGacacactttggaaacacacaATGATCTATCCAAAGCTTCCTTCATGCAACGTAATAGGTTGTTTGAGTATTTTGTTAGATTGGACATAACGGAACTCATTTGTAAAATATGTGGTATCAATATTGATACTTTGGAAAATCTAATGGCACATCTTAAATCCGATCACCAAATAAAGATATTCACAGATATCAAAAACCATATATTACCGTTCAAATTTGAAACGAAATCGCTTCAATGTTTCATGTGTTTAAATGTATTcaacaaattcaaatcattgctGGAGCATATGAACTCGCATTACAAGAATTATGTTTGCAATACATGCCAGGCGGGTTTTGTAAACATGAGGCAGTTGACAAATCATAGGCCGTCACACAAAACAGGCACTTTCAAATGTGGTTATTGCGATAAAGTGTTCGATACACAAGCAAAGAGACGAGGTCACGAAAAAGGGGTGCATATTTATAAGAATGTTTTGCACAAATGTGGGTATTGCAACGAGAGGTTCACACTGCCGCGTTTGAAAGACGAACATTTAAAATCGGTGCACGGTGTGAGGATTTCTTTCAATTGTCAAGCTTGcgataaaacatttaattctaCGAAGCTACTCAATTCACATACGAAGAGGGATCATTTAATGGAGAGATTTTTTAAATGCAAACAATGCGATAAAGAGTTCTTCGCAGTTGGACAACTGAAAAATCATATGCTTAGTCACACCGGTGAGAGAGAATATAAATGCGACGTGTGTCTCAAATCTTACGGAAGGAAATATACACTGAAAGAGCATATGAGGATACACGCCGACGACCGCAGATTCAAATGCGAGCACTGCGGACAGGCTTTTGTGCAGAAATGTAGTTGGAGGGGACATATGCGCTCCAAGCATGGGGAAATAGTTTAA
- Protein Sequence
- MHLIPDRLSSKRQKLIRIDVKDVNTKEIVATRELSYVDTDKDEDYILIIEKSNDSGDENQTVKTSSTVKENGMVNTDKLKTVVQSNNNRKEDATAKYKHLTNIKAVLEYSNATIIRHRGGIGYVCSFCPEQYPDAADLKRHTLERHNDVNQCYINNISICDNIIKVDITSLRCKLCDSNIKSLEDLMEHLQNTHGVKIFTDIKNQMIPLKFDTKILTCAICDNGAVYNKFKSLLEHMKVHYRNYVCQECDAGFINPAQLRVHMNFHDIGNYACEICGKVFTNGRTLKAHVRAVHIIKSQPAYKCGYCNESFQFFHSKERHLQKVHGVVMAPINCQACDKSFTTRSTYLAHMKLNHLMIRPHACTQCNKSFTYSAALKEHEGRVHMGLKLYECDLCNKHFSTKNALRQHIRIHTNDRRYKCQICGQAFVAKSSGGQAYATREINEVETRTGVVKRKDDQNKVDLRKRKRKDDASVLRKHYVNIREILKHSNATPIRSRGGIGYACSFCTDQYPDPADLKRHTLETHNDLSKASFMQRNRLFEYFVRLDITELICKICGINIDTLENLMAHLKSDHQIKIFTDIKNHILPFKFETKSLQCFMCLNVFNKFKSLLEHMNSHYKNYVCNTCQAGFVNMRQLTNHRPSHKTGTFKCGYCDKVFDTQAKRRGHEKGVHIYKNVLHKCGYCNERFTLPRLKDEHLKSVHGVRISFNCQACDKTFNSTKLLNSHTKRDHLMERFFKCKQCDKEFFAVGQLKNHMLSHTGEREYKCDVCLKSYGRKYTLKEHMRIHADDRRFKCEHCGQAFVQKCSWRGHMRSKHGEIV
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -