Gmel021375.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Galleria mellonella
Gene Symbol
-
Assembly
GCA_958496185.1
Location
OY292310.1:2102711-2113366[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 40 0.073 4.8 8.3 1.1 1 21 79 99 79 100 0.96
2 40 0.71 46 5.2 0.1 2 23 128 149 128 149 0.95
3 40 0.023 1.5 9.9 0.6 2 23 172 193 171 193 0.97
4 40 0.031 2 9.5 0.1 1 23 197 219 197 219 0.95
5 40 0.077 5.1 8.2 0.4 1 20 224 243 224 247 0.79
6 40 0.2 13 6.9 0.3 3 23 255 276 253 276 0.94
7 40 0.012 0.8 10.7 0.7 1 23 283 306 283 306 0.96
8 40 1.3e-06 8.2e-05 23.3 1.1 1 23 313 335 313 335 0.98
9 40 5.1e-06 0.00033 21.4 1.3 1 23 341 363 341 363 0.98
10 40 0.0093 0.6 11.1 0.2 1 23 442 465 442 465 0.96
11 40 6.4 4.2e+02 2.2 0.9 2 23 492 514 491 514 0.92
12 40 0.28 18 6.4 4.7 1 23 536 558 536 558 0.98
13 40 5e-06 0.00033 21.4 0.7 1 23 562 584 562 584 0.98
14 40 1.6 1.1e+02 4.1 1.4 1 16 589 604 589 612 0.77
15 40 0.0074 0.49 11.4 0.9 1 21 618 638 618 641 0.90
16 40 0.00045 0.029 15.2 0.2 1 23 648 671 648 671 0.97
17 40 0.00018 0.012 16.5 1.5 1 20 678 697 678 697 0.97
18 40 6.3 4.1e+02 2.2 0.2 1 23 746 768 746 768 0.93
19 40 0.0012 0.076 14.0 1.2 2 23 793 815 792 815 0.96
20 40 0.00074 0.048 14.6 0.5 1 23 837 859 837 859 0.99
21 40 1.6e-05 0.0011 19.8 3.7 1 23 863 885 863 885 0.98
22 40 0.0093 0.61 11.1 0.5 1 23 890 913 890 913 0.94
23 40 0.54 35 5.6 1.3 1 20 919 938 919 942 0.75
24 40 6.4 4.2e+02 2.2 0.3 1 10 948 957 948 959 0.88
25 40 1.5 1e+02 4.1 0.0 2 23 1046 1068 1045 1068 0.94
26 40 0.022 1.5 9.9 2.8 1 23 1090 1112 1090 1112 0.96
27 40 0.004 0.26 12.3 0.4 3 23 1118 1138 1117 1138 0.95
28 40 0.0061 0.4 11.7 1.6 1 23 1146 1169 1146 1169 0.94
29 40 0.0035 0.23 12.5 2.2 1 23 1175 1198 1175 1198 0.97
30 40 0.41 27 5.9 2.8 1 23 1204 1227 1204 1227 0.96
31 40 0.00092 0.06 14.3 0.6 1 23 1233 1255 1233 1255 0.95
32 40 1.9 1.2e+02 3.9 0.1 2 23 1364 1386 1363 1386 0.93
33 40 0.32 21 6.3 6.7 1 23 1408 1430 1408 1430 0.95
34 40 0.0003 0.02 15.8 0.6 1 23 1434 1456 1434 1456 0.98
35 40 0.0052 0.34 11.9 0.1 1 23 1461 1484 1461 1484 0.95
36 40 0.00034 0.022 15.6 1.9 1 23 1490 1513 1490 1513 0.97
37 40 0.14 9.4 7.4 1.2 1 23 1520 1543 1520 1543 0.95
38 40 0.00017 0.011 16.6 0.9 1 23 1549 1571 1549 1571 0.96
39 40 2.3e-06 0.00015 22.5 1.0 1 23 1577 1599 1577 1599 0.99
40 40 9e-07 5.9e-05 23.7 2.6 1 23 1605 1627 1605 1628 0.96

Sequence Information

Coding Sequence
atgctcacaacaattaagcagatgtacaatgttataagATTCCAAGGACAAGTCAATGAGACCGTAGTAGATGTAGGAGCGACTGGAAATGTAGTGAGACGAGAGGAAAAGGTCGAGGAAAAACGGCGGTACCAGAGGAGCGCGCGAGCAGAGGCTCGAATTATCATAAAGAAAAACGCCGCTTCCATACTGGAATGTTGGGCTCTCTGCCCTTTTAGATGGAAAAGGAACAAATTCAAATGTTCCTATTGTGAAGCTTACTTTACTGAATGCAATTTGTTAAGAGACCATGTTAGAGCGTGCTCCTCCCAGCATAGCGTTAAGGACATTTATAGTAAATTCAAAGAAATGCCCCTAATAAATGTCGATGTAACTGACGCAGTATGTCGAGTATGCGCTGTTTCATTCAGTGATATAAACCAAATGCGCGATCACGTTGCAAAACACAATTTCTGCTTTGACACGAAGCACCCAGATGGGGTGCTGCCTTTCAGTTTGGACAAGGAATCGTGGAAGTGCGTGGTCTGCAAGGAGAAGTTCAATAATTTCCTCAAACTCTACGAACATATGAATGTTCACTACCAGCATTATATATGCGCGACATGCGGTAAAGGGTACATGACTGCACCACGGTTGAGGAAGCACTCAGAAGTTCATATAAGTGGAAAATTTCCATGCAACGAATGTGATAGGGTGTTTACAATGCGCGCTGCCAGAGATTCTCACAAAGCGCACGCTCATGCAAAGGGGCCGCGGTACGGATGCCCCCATTGTAATATGCGTTTCGAAGGGTACTACGATAGAATGGCGCATTTAAACGAGGCGCACAGCGAGAAAGCGGTGTCATACGATTGCGCGCACTGCGAGCTGTCCTTCAAAACGAGCGGGAAGCGTGCCGTTCATGTTCGCTCCGTTCATTTCCCGCCGCAAAGGGATTATAGTTGCCCGTACTGTGAATGGCAATTCAGAACTAGTTACGAACTGAAGAGACACATGGTTCGACACACGGGAGAGAGGAATTTCCATTGCAACGTGTGCGGGAAGTCTTTCCCGAGGAACAGAGCTTTGTTGTCCCATTTGAAAGTGCACGAGGAGTTTTGTTgtTCCGCTTTAGCGGAAGAGGAGTCGAATGTAGGTGAAGATAAACGTGGTAGGAAGTTAAAGGAAAACGTTAGCGATCGACAGTTGAGAAGGCGACGGCGTGCCAACAATCAGTTGCCCGAGGAATCTGAAAAGCGCATAGCTAAAACAATGATGCGAAGGAACGCTATTACGTTACTAGAAAGTTCCACAGCTTGGGCGTTTAGGTGGTTTCACGGCACCTTCTACTGTTCATACTGCGAAGAAAGATTCGCCGACATAGATCCCTTACGCGACCACGTCCTCAAAAATCATATTAACGAGCAACCCACAAAGAAAATCTTTACAAAGCTCAGGGAAAATAATATGGTTAAAATTGATATAGGTGATCTTCAATGCAGGATCTGTAATTGTTATATAGACAGTGTTGACTCTTTGAAGGATCACTTGGTCTCGTTCCATAAAAAGACCTTGTTCCTTGACTACAGTGACGGGGTCCTGCCATTTAAGCTACAAATGAACAGTTTCTATTGCCAGAAATGCTTCGAGCATTTCGACACTTTCACAAAAGTCAACGAGCACATGAATTCTCATTACCAAAATTATATCTGCGAGGAATGTGGCAAAGCCTTCGTGTCGAAGTCTCGTTTCAGAAGACACGTTCAGTCTCACGAAATAGGCACATTTCCATGTTCAGATTGTAAGGAAATATTTAACACTCGTGTTGCTAGGTTGTGCCACAGGATGAAAGTACATCGGAAAGGTATTAGATACACTTGTCCGCGATGTCCTGAAGTGTTCACTCATTATTATAGTAGAGCCAAACATTTAGTAGATGAGCACGGACAACAGAAAATCGATTATGACTGTCCAGTTTGCGGCAAAACTTACGAGACGGCTTCGAAGCGCGCGGCGCATTTTCGCATGACGCATACTAATGTTGAGAGGAAATATCGATGTTCTCAGTGTAATTATTCTTTTGTTACGAAAGGGAAACTACAGCGGCACAgACCCGATGGGATTCCGTCATTGGACATGGAGTCGCCAATTAAAGTTAATTGGAAACGAAAGCGGAGGATTGTAGAAGACAAAGCCAACGCAGCTCTAATTCTTCAATACTCAAACGCAGTTCCGTTTCGGTATAAATTCGGGAAATTTATGTGTGCATACTGTCCATCTGTTTGTGCGAACGTCAATGAAGTAAGAATACATTCAGTGACGCACGATAAACCAAACGTTTTCGAAAATCCAGAGGTTCGCAATTCGTTTCCACTTCGTGTTGATATTACAGATTTGTCGTGTAATATATGTGATAAGTCAATAGATACGCTGAAGCATTTGAAAGAACACCTCACGACAGAACATGCTAAACATATAAATCCTGAATATGGCGATGGTGTTATACCATTCGTTTTAACAGGAAAAGAATATAAATGTGTTCATTGCGGTGTGGCTGTGGAAAACTCGATGAGTCTATTTGTACATATGAACAAACATTATCAAAGTTACGTATGCCATACTTGCGGTAAAGGATTCTCTGGGAAACACAAGTTACGCGCCCATCAGATGTCGCACGAGTCCGGTCAGTTTGCATGTACGAAATGCGAATTAGTTTTTTCTAATCGCACCGCGAAGAATAGACATACTTCCATTGCTCATGGACCCAAGGAGAGATACAGATGTCCAGTATGCGATATACATTTCGACTCGTATCACATTCGATTAAGACACCTTGACAGAGCTCATGGCCAGAAAGCAGAGTATCGATGTAATTATTGCCCAGCAATATTTGGCAGTGgAGCCATCGACAACAAAGTAAAATGGAAACCGAAGCGCAAGTATAACGATCAAAGAGACAATGCAGCCATAATTATAGAGTGTTCCAACGTTGTACCGTTCAGATGGAAACGGGGCGCGTTCACATGCGCGTACTGCTGTTTAACTTTCGGTGATTTTAAAGGCCTAAAAGATCACTTTATAGAACATCCTAATAAGATCGAGGCCATGCGACTTGCACGCACCATAGATAACATAAAAGTTGATATCAGCGGACTTAAATGTGAACTGTGTTCAGATAGCATTAAAGATTTAGATGCCCTTAGAGATCATTTGATTAGCGTTCACAATAAGCCAATAAACAAAGAGGCAGGTTTAGGTTTAATGCCATTCTTGTTAGAAGGCAAAGAGTACCTTTGCACTCACTGTGATGAACGGTTCGAATTGTTCACCAAATTGAACACTCATATAAATAACCACTATCCTAACAATATATGTTTTCAATGCGGTAAAGTTTTTTCTGCAGCGCATAGACTTAAAGCACATTTAGTTATTCACGAGGAACAGAATGGTGAACAGTACAAATGTACCAAGTGTGAACAAGTTTTTGCAACTAGAGTTCATAGGAGTAATCATATAGCTTTAACACATGGACCTGAATATAGATATCGTTGTCCATACTGCAACGATTCGTTCAAACGTTATGCTGATAGAAATAAACATCTCAAACAATCGCACGGTAAAAAAATCGAATACGCATGTCACCTTTGTTCGGCTGTTTTCGCGATGTGTAACCAAAGGACTAAACACATAAAGCAGGTTCATATAAGACATAAGCAGTTCTTATGCACTTTCTGCCCCTATAAATTTGTGACCGGTGCTCAATTGAGAAATCACATGATCAAACATATAGgAAGAAAATCTGAAGAAATAGAGATTAAGACCGAAGTGGAGTCTGACACAGAGAATAATACAGCAGCAATTTTAGCAACAGCGCGCGATATGGGAAACGAGAGACGGGCGGCGTTCAGGAATAACATATCGGTTATCATGGAATCATGCACAGCTTACCCATTCAAGTACAGGAAGGGCACTTACCTGTGCTTCTTCTGCAAAAGTACATTTCTGGAGCCGGAGAAACTCCGCGAACATAACAAAAGGCAACATTCCGATATAAAGCAGCTTTTGAAGCCGCGAAAATACGAACCGTTAAAGATGGATTTCGCGACGACTTCCTGCAAGTTGTGCGGTGCTAATATTATGGATTACGCTATGCTGAAAGTCCATTTGACTGTGGAACATGGAAAGATGATAGATATCTCGCACGGAGAGAGCGTTCTGCCTTATAAACTAAGTAAAGACGAACATTGTTGTCAAATATGCGGAAAACGTTACGAGATGTTTCTGAGCCTTCATAAACACATGAATGATCATTACGAACATTTTATTTGCGAAACATGCGGTAAACGTTTTGCCACATCGCAGAGAATGGTGAATCACGCTCGCACACACGAGCGCGGTGACTTTCCATGTAAACGGTGTGAAGAGACTTTCCCATCGTACGCGTCTTTATACGCTCACGTGGCAAAGGTGCACAGATCGAACAAAAGATACAAGTGTCCCATCTGTGATGAAAAATTCGCATCTTACAAACATCGATTGAAGCATTTAAACTCGGTGCACGGCGAGAAAACGGCAGTATTCCCGTGCCCTTCTTGCCCTAGAGTTTTTGATTTGTGTAGCCGGCGCACTGCTCATATTAGGTTCCAGCACCTACAAGAGCGAAACCACGTTTGCCCTATCTGCGGTATGAAGTTCTTCACCAACTATGAGCTCCAGGAGCATTCCATAAAACACGGCGGAGCTCGCATATATCAATGCGACGTTTGCAAGAAGTCCTACGCTAGGCTAAAGACTTTGAGAGAGCATATGAGGATTCACAATAACGATAGGAGATTCGTGTGTCCGGTTTGTGGACAGTCGTTCATACAGAACTGTAGTCTGAAACAACATATGAGGGTTCACCACCCCACGCATATGAAGGTAGATATGTTTTAA
Protein Sequence
MLTTIKQMYNVIRFQGQVNETVVDVGATGNVVRREEKVEEKRRYQRSARAEARIIIKKNAASILECWALCPFRWKRNKFKCSYCEAYFTECNLLRDHVRACSSQHSVKDIYSKFKEMPLINVDVTDAVCRVCAVSFSDINQMRDHVAKHNFCFDTKHPDGVLPFSLDKESWKCVVCKEKFNNFLKLYEHMNVHYQHYICATCGKGYMTAPRLRKHSEVHISGKFPCNECDRVFTMRAARDSHKAHAHAKGPRYGCPHCNMRFEGYYDRMAHLNEAHSEKAVSYDCAHCELSFKTSGKRAVHVRSVHFPPQRDYSCPYCEWQFRTSYELKRHMVRHTGERNFHCNVCGKSFPRNRALLSHLKVHEEFCCSALAEEESNVGEDKRGRKLKENVSDRQLRRRRRANNQLPEESEKRIAKTMMRRNAITLLESSTAWAFRWFHGTFYCSYCEERFADIDPLRDHVLKNHINEQPTKKIFTKLRENNMVKIDIGDLQCRICNCYIDSVDSLKDHLVSFHKKTLFLDYSDGVLPFKLQMNSFYCQKCFEHFDTFTKVNEHMNSHYQNYICEECGKAFVSKSRFRRHVQSHEIGTFPCSDCKEIFNTRVARLCHRMKVHRKGIRYTCPRCPEVFTHYYSRAKHLVDEHGQQKIDYDCPVCGKTYETASKRAAHFRMTHTNVERKYRCSQCNYSFVTKGKLQRHRPDGIPSLDMESPIKVNWKRKRRIVEDKANAALILQYSNAVPFRYKFGKFMCAYCPSVCANVNEVRIHSVTHDKPNVFENPEVRNSFPLRVDITDLSCNICDKSIDTLKHLKEHLTTEHAKHINPEYGDGVIPFVLTGKEYKCVHCGVAVENSMSLFVHMNKHYQSYVCHTCGKGFSGKHKLRAHQMSHESGQFACTKCELVFSNRTAKNRHTSIAHGPKERYRCPVCDIHFDSYHIRLRHLDRAHGQKAEYRCNYCPAIFGSGAIDNKVKWKPKRKYNDQRDNAAIIIECSNVVPFRWKRGAFTCAYCCLTFGDFKGLKDHFIEHPNKIEAMRLARTIDNIKVDISGLKCELCSDSIKDLDALRDHLISVHNKPINKEAGLGLMPFLLEGKEYLCTHCDERFELFTKLNTHINNHYPNNICFQCGKVFSAAHRLKAHLVIHEEQNGEQYKCTKCEQVFATRVHRSNHIALTHGPEYRYRCPYCNDSFKRYADRNKHLKQSHGKKIEYACHLCSAVFAMCNQRTKHIKQVHIRHKQFLCTFCPYKFVTGAQLRNHMIKHIGRKSEEIEIKTEVESDTENNTAAILATARDMGNERRAAFRNNISVIMESCTAYPFKYRKGTYLCFFCKSTFLEPEKLREHNKRQHSDIKQLLKPRKYEPLKMDFATTSCKLCGANIMDYAMLKVHLTVEHGKMIDISHGESVLPYKLSKDEHCCQICGKRYEMFLSLHKHMNDHYEHFICETCGKRFATSQRMVNHARTHERGDFPCKRCEETFPSYASLYAHVAKVHRSNKRYKCPICDEKFASYKHRLKHLNSVHGEKTAVFPCPSCPRVFDLCSRRTAHIRFQHLQERNHVCPICGMKFFTNYELQEHSIKHGGARIYQCDVCKKSYARLKTLREHMRIHNNDRRFVCPVCGQSFIQNCSLKQHMRVHHPTHMKVDMF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-