Basic Information

Insect: Galeopsomyia nigrocyanea
Gene Symbol: ZFHX3
Assembly: GCA_035047105.1
Location: JAWWMK010000024.1:7198-15975[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.097 16 7.4 0.1 2 23 48 70 47 70 0.93

2 11 0.0033 0.54 12.0 1.0 3 23 91 112 90 112 0.95

3 11 0.0067 1.1 11.0 4.0 2 23 174 196 173 196 0.96

4 11 0.00052 0.085 14.5 0.8 1 23 213 235 213 235 0.97

5 11 0.055 9 8.1 4.8 2 23 242 264 241 264 0.96

6 11 0.05 8.2 8.3 5.8 1 23 354 378 354 378 0.91

7 11 0.0029 0.48 12.1 0.6 1 22 398 419 398 422 0.89

8 11 0.0019 0.3 12.8 0.5 1 23 463 487 463 487 0.92

9 11 0.0027 0.43 12.3 0.3 1 21 533 553 533 554 0.95

10 11 0.088 14 7.5 2.0 2 19 701 718 700 723 0.91

11 11 0.17 28 6.6 0.9 2 22 974 994 973 997 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.097	16	7.4	0.1	2	23	48	70	47	70	0.93
2	11	0.0033	0.54	12.0	1.0	3	23	91	112	90	112	0.95
3	11	0.0067	1.1	11.0	4.0	2	23	174	196	173	196	0.96
4	11	0.00052	0.085	14.5	0.8	1	23	213	235	213	235	0.97
5	11	0.055	9	8.1	4.8	2	23	242	264	241	264	0.96
6	11	0.05	8.2	8.3	5.8	1	23	354	378	354	378	0.91
7	11	0.0029	0.48	12.1	0.6	1	22	398	419	398	422	0.89
8	11	0.0019	0.3	12.8	0.5	1	23	463	487	463	487	0.92
9	11	0.0027	0.43	12.3	0.3	1	21	533	553	533	554	0.95
10	11	0.088	14	7.5	2.0	2	19	701	718	700	723	0.91
11	11	0.17	28	6.6	0.9	2	22	974	994	973	997	0.89

Sequence Information

Coding Sequence: ATGTGTCACGAGTTTATTAATCATCGCCGTGAAGATAACAGTAATTGTagcaatcaaataaaacaagaaataGAACATGATCAAGATCTAGACCACGAACAAGAACAAGAACAGGAGCAAGAAATAGAAGCCGAAGACATAACTTGTTCATTATGTCCTTTTCAAGCGTCATCGAGTAATGAACTCAAAAGCCATCTCCAAGATGGACATGTTCACAAAAATGacgaaataaatgcaaatttcaAAGATGATTTAAATGTAGATCTTTTATGTCCTCTGTGCCAAGATAGTTTCAAACAACGTCATGATTTAGAAAAACATGTAATGCAAATTCATTCTGTGAACACTGATGGGTTGCAAAGACTTTTACACCTCGTAGATCAAAGTCATTGGTTAAATATTAATCCTCAAAATTTAAACGCATCAGTATCTTGCCAATCATCTCAGCTTCTTGTATCTAGCAAATCTCAAGAAGAAGAGAACCTTGAACAAGTTAttagcgaagaagaagagataTCAAAGTGTAATATTTGTCAGAGAGTATGTCGATCAGTAAAAGAGCTTCAAATACATCACCGTGAATCTCATTCAACGGTTTTGCCATCTCTCGCTGTCAGTGAAAAACATGTTTACAAATATAGGTGTGGTCAATGCAGCCTCGCTTTTAAAACGTTAGATAAACTACAACAACATGCACAGTATCACGCTATCCGAGATGCCACTAAATGTACTATATGCTGCCGTTCTTTTCGGTCCGTGCAGTCACTTCATCGTCATTTAGAAACAGCTCACTTAGAACTGCAAGAAGATGAATTGGCacaatataaacaaaatcTAATAAGTTCTCATCCTTTACTGCAAGCGCTAACGGAAGAAGCTCTTCGACAACAAGGGTTGTTTAATAGCGAAAATATCAATGAAGATGAATCAAAAGCTGGTGACGATGAAGACACCGATCTTAGTGATTTATCACCTCTGCGTAAAGAACATCAGTTATTAGAAGAATACCTAAATAGTCAATCCATAGCTGAAGATTCTTACAGTGATCCTgaacgaaaattcaaatgtcaCAGGTGTAAAGTTGCTTTTACAAGGCAATGTTATTTGACTGGACATAATAAAACACTTTTGCATAGAAAGGGTGAAAAAATGCCTTATcctatggaaaaatatttagaccCAAATAGGCCATACAAATGTGATGTATGCAAAGAAAgtttcacacaaaaaaatatcttactTGTACATTATAACAGTGTTAGTCATTTGCATAAACTAAAAAGGGCTATGCAAGAACAAGGCAATAATAATACTCTCATAACTGTTGCGCCTTCCATAAGTCCAACCGAGTCAAGCGACAGTCAACTCGAATCAGATAAAAAACCATATAAGTGCAATATTTGCAAAGTTTCTTATTCTCAAGGAAGTACTTTAGATATACATAAAAGAAGTGTTCTTCATCAAACACGTGCCAGCAAAATTCATGATCTTACCATCACTGGTCAAATAGATTTGACAAAGCCATTGATCGAACAGCCTACATCTAATCCTAACAGTCCATCTTGTAGTAATAATCTGGAAAACAATACTTCCATGTTTTCTTGTTCGAAATGTAGTGCTCTGTTTATTACTCAAGAGCAGCTCACTAATCATCAACAAATGTACTGCATTTTTAGTAATCCACTTGCACTGTTTCAACAAATCACAGCATCTCAAAAAGAACTAATATCACCATCAAAAACTCCTCCTCCATCAGTATCGTCAACTGGGTTTCCTGAGAAAAATGTGCGATCACCAAGTTCTTTGAGTATCATGACTTCTCAagacattttttatcaacCAAAACACAAAACTTCACAAATATACAAACATTTGCTTGAAAGTTTTGGCTTTGATTTAGTCATGCAGTTCAATGAGAATCACCAAAGaaggcaaagaaaagaaagcgaaGAAAACGTAAATGCATATCGCATACCAATTCAAGAGTCCATAAATACAGATTATCAAAATCGAATTATTGAAAACCAACTTTGCCATGAAAAAGAACAGGATCAATATGAAATCGGCGATGAAGACGTTATtccagaaattaaaaaaagtacttgtCAACACTGTAATAAGGAATTTAGTAGCGTGTGGGTTCTCAAAGCTCATTGCGAAGAAGTACATCGTGACTTAGTGCCCCGTGAATTTCTTGAAAAGTATGCACAGCAATTCAAATGTGAATATGAGAAGAAGACCGTCATTGTAACGGCTGCTACATCATCGTCAGCAACAACTGGACCAATTACTAGCATACCAACATTACTTCATGTTCAAGACACCTTGTCagagaataaagaaaaagacgatTCATCGGAACACAAAGAAACGAACAATAAATCGCCAGAAGCGACTTCTACCACACCAAATACTACGCCAGCACTAAGTAACACACCCGTATCAAGTACAGGTTCAGTAACGCCTACAGTCCTAAGTAACATCTCACAAAATACCATTCAACATCAACAAGCTCATTTGACATTAGCTCAGCATATGTCTGAAGTTCAAGCTGCGTGCATTAATGCATTAGCAGCATCGCATCTACAGCAACAACTTCATCAGTATCCAAGTTTGATGATGAGTATGATGGGGTTACCAATGGGTATCAACGTACCAGCATTAGCAGCAATGAACTTGCAACCTCCTTTGGTACCAATGATGTTACCACCCCAAAATTTTGATGGAAGTAACATTGCTTATGTCTCATCACCAACACAGTCTGATTTACTTACAAAACAGCATCTAAATATACAGCATTCGCAACAAACTGCTTCCgTATGGTTCCAGAATGCAagggcaaaagaaaaaaaagctagatTAGCAGCTGGACTGTCTGCTGATGGCGCTATAGTTCACCGTGGATTGACTGGCCCTGACGAATGTAAACTATGTTCTATTCATTATTCTCCTAAGTCACCGTTACAAGAACATATATTCTCAAGAAAACATATTGAATCGGTGAGAACTGCCGTTGAAGAAGGTACGTTAGTACCACCCACTCCTGGAGCTCCTATTAGTAGGGAAAGTGCCATTGCAAGTTCCGCGATTAATAATCTGCAAGGCAACCAAACGCAGACTGATGAAAATATGATGTACGGGTCGTTGTTCCTCCATCCCACGGCAATGTTTCAgtcgcaacaacaacagcaacagcaacataCCGGGAATGTCACAACCAGCGCGACCACCGCCACAGCCGGTGAGTGTCTGGCTGACCTTTTAGATTCCTAA
Protein Sequence: MCHEFINHRREDNSNCSNQIKQEIEHDQDLDHEQEQEQEQEIEAEDITCSLCPFQASSSNELKSHLQDGHVHKNDEINANFKDDLNVDLLCPLCQDSFKQRHDLEKHVMQIHSVNTDGLQRLLHLVDQSHWLNINPQNLNASVSCQSSQLLVSSKSQEEENLEQVISEEEEISKCNICQRVCRSVKELQIHHRESHSTVLPSLAVSEKHVYKYRCGQCSLAFKTLDKLQQHAQYHAIRDATKCTICCRSFRSVQSLHRHLETAHLELQEDELAQYKQNLISSHPLLQALTEEALRQQGLFNSENINEDESKAGDDEDTDLSDLSPLRKEHQLLEEYLNSQSIAEDSYSDPERKFKCHRCKVAFTRQCYLTGHNKTLLHRKGEKMPYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTLITVAPSISPTESSDSQLESDKKPYKCNICKVSYSQGSTLDIHKRSVLHQTRASKIHDLTITGQIDLTKPLIEQPTSNPNSPSCSNNLENNTSMFSCSKCSALFITQEQLTNHQQMYCIFSNPLALFQQITASQKELISPSKTPPPSVSSTGFPEKNVRSPSSLSIMTSQDIFYQPKHKTSQIYKHLLESFGFDLVMQFNENHQRRQRKESEENVNAYRIPIQESINTDYQNRIIENQLCHEKEQDQYEIGDEDVIPEIKKSTCQHCNKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKTVIVTAATSSSATTGPITSIPTLLHVQDTLSENKEKDDSSEHKETNNKSPEATSTTPNTTPALSNTPVSSTGSVTPTVLSNISQNTIQHQQAHLTLAQHMSEVQAACINALAASHLQQQLHQYPSLMMSMMGLPMGINVPALAAMNLQPPLVPMMLPPQNFDGSNIAYVSSPTQSDLLTKQHLNIQHSQQTASVWFQNARAKEKKARLAAGLSADGAIVHRGLTGPDECKLCSIHYSPKSPLQEHIFSRKHIESVRTAVEEGTLVPPTPGAPISRESAIASSAINNLQGNQTQTDENMMYGSLFLHPTAMFQSQQQQQQQHTGNVTTSATTATAGECLADLLDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00326635;
90% Identity: iTF_00326635;
80% Identity: -