Basic Information

Insect: Galeopsomyia nigrocyanea
Gene Symbol: mecom-b
Assembly: GCA_035047105.1
Location: JAWWMK010000008.1:7820132-7847443[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.25 41 6.1 0.8 2 23 329 351 328 351 0.84

2 8 2.8e-05 0.0046 18.5 1.2 1 23 387 414 387 415 0.91

3 8 6.1e-06 0.001 20.6 2.6 1 23 421 443 421 443 0.95

4 8 3.8e-05 0.0061 18.1 5.0 1 23 449 471 449 471 0.99

5 8 0.045 7.3 8.4 1.1 2 21 479 498 478 499 0.94

6 8 3.2e-08 5.2e-06 27.8 1.7 1 23 909 931 909 931 0.99

7 8 4.6e-07 7.5e-05 24.1 1.7 1 23 937 960 937 960 0.97

8 8 9.6e-06 0.0016 20.0 3.5 1 23 966 988 966 988 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.25	41	6.1	0.8	2	23	329	351	328	351	0.84
2	8	2.8e-05	0.0046	18.5	1.2	1	23	387	414	387	415	0.91
3	8	6.1e-06	0.001	20.6	2.6	1	23	421	443	421	443	0.95
4	8	3.8e-05	0.0061	18.1	5.0	1	23	449	471	449	471	0.99
5	8	0.045	7.3	8.4	1.1	2	21	479	498	478	499	0.94
6	8	3.2e-08	5.2e-06	27.8	1.7	1	23	909	931	909	931	0.99
7	8	4.6e-07	7.5e-05	24.1	1.7	1	23	937	960	937	960	0.97
8	8	9.6e-06	0.0016	20.0	3.5	1	23	966	988	966	988	0.99

Sequence Information

Coding Sequence: ATGGCGTGTCTCGACTTGTCCACCTCGGCGATGGTCGATTACAAGAGCAGCGGAAGCAGCGACGAGGGCGAGACAGCAGGTGGAAGCGGGGGCGGCGAAAGCGCAGAGATGGAGGAGAATAGTTCGTTACGTTCGtcgagcagcaacagcaatGGACCAGCCGGCCAAGTCGACCTGTACGGCGCATCGAATGAGCACCACCATCACATGCCCGACACAACCTCCAACAGCAAGAGGTGCCTCGATGTCTTTCGCGAAACTTCGTACTCGCCGCCAAGGTTGCGACATTTGCCGCCTAGTAATGctgttgccgccgccgctgctgctgctgctgccctgCAACACCCACACCAGCCGACTTACAAGCGGCCGTTCGAGGACTATCCACTCGTCGCCTGGGACTTTAGTGAGAAACACGCCCTCGAGACCAGGAAATACTTCAAGAGGGATTACGACGACGAGCAGCTAAATGCCATAAAACGGGAACCCGTAAGTGCAAAAAATCATCTATCGCCCGACTGGTCAATTCCGGTGCCGGACAACGTAGAGATAAGTCACTCGTCGTCTGGGAACCAGTACGTCCGGGCGTGCAAGGAAATCGCCGAAGGCACGAGGTTCGGCCCGCATCAGGACAACTGGTACAACACGGACTTTACTCCTTCAAACGCCAGCGAAGTGCTGTACGCCTGGAAATTAGCACGCGAGTCATTCGAGGAATCGAGGGATTGGATGAAGTTCATTAGAATCACGATCAATCCAGACGAAGCAAACGCGCGAAAAGTCAAAGATAAGGATGGAAATACGTACTTGGAAGCGATCCGCAACATATCGGCCAAAGAGGAGTTGGTGAGCTACATCGAACCGTACAGCCATCATCAGCGTCGGATAACCAACGAGGACGAGAACACGAGCGAGTACGCCTCTCAACACAGTGGTGCTTCGCACGCCGACGAAGAcagggacgacgacgacgacggtgaaACAAGGTGTACAGTCTGCGACAAGCCGTTCCAAGATATCGAAATtttgaACAATCACCTGGTCAATTGCCACAGATATCCAGATCGCGAGCACTGCTGCACGAGCTGCTCGAGCGGCTACGCCTGGCGACCACTGCTGATTCGCCATCGCGCCCTCGTCCACGGCGACGTGCGCAAGTACCCTTGCGAGAATTGCACCAAGCCGGACCATCCGCAGGTGTTCACCGACCCGTCCAACTTGCAGCGCCACATCCGAACCCACCACGTTGGCGCGCGCAGCCACGCCTGCACCGAGTGCGGCAAGACCTTCGCCACGAGCTCGGGCCTCAAGCAGCACACCCACATCCACAGCAGCGTCAAGCCCTTCCAGTGCGAGGTCTGCTTCAAGGCTTACACCCAGTTCTCCAACCTCTGCCGGCACAAGCGCATGCACACCAAATGCCAATTGAAGATCACCTGCAACAAGTGCAAAGCCCAGTTCAACACCATCACCTCGCTGTCCAAGCATAAGCGATTCTGCGACTCGACCGCCACTCTGCCGCCGACCTCCAGCTCCGCAGCCGTAGCCGCGTCGGCCGCCGCACTGGCCGCAAACATGCCTCAGCCACAGCCAAATCCCTTCCTCTTCCCGAGGCAGCCGCTGCCCTTCTACCCGCCCAGTCTCATGAAGTACTACTCGGCCAATCTGTTTCGCGGAACGACAGACAACTTGCTGGGCTTTCCGATGCTCTACCCACCCAAGCCCGACGACTTGGACCGAGCCTCTATCGAGGGAACCATGGGCTCGGACAGCCCAAAGGCTTCGCGGGAGAGATTCACTCCGCCGCGAGCTGCCCCGCCACCGCCGCAAGCATCGACGATTCAGCAGCCACAGCCCGTTCCGCAGAAGGTGTCGCCCACCTCCGCGGAAGAGGCAACGTCGAATCTGAGACCGTCGCCGGCTCGGCCACCCGCGCCACGCTCCGAGGAGTCAAATAGTCCCAGGCAGGGGAGCAGTCAGCAGCACAAGAGCAAGCCTCGTCAGAGCTCCGTTGAGCCAGAGCCAGagaatcatcatcatcatcatcagcagcagcagcaaaattCAGAGCAGCCGCTGGATTTGTGCGTGCGAAATAAACGCCAGCTGCCGGTGGAATCTCCAATATCGAGCCTTGCACCGACAGAACCAGAGCGAGAGCCTACGCCAAAGCGTCGCCGAAGCGAGTACTCCGAAGAGTCGCCCAACCAGACCAACTCGCGGCCCTCCAGCAGAGTCAAGAGTGTCGAGCGTCAGAGTCTCGAGAGAGCGCCTTCAGAGAACAAAGAGATCAGCAGTAGCCCGCTGCCAAGGAGCAGCAGTCAAGTGCAACCGGCCGAGAGCCAATCGGCGAGCGAAAGAACGCCAACGCCGCCGCCTCCGCCGCCACCACACATGGCTTATCCTCGACCCATTCACCCGCTGTTTCTCGAGTCGATGTACCGCAACTCGTCCGCAGCTTTTCCCAGTTTCCCGGCAGTCGGCGGGGTCTCCGGCTCGAGCAACTCGGCGGACCATCGCCTCTTGCAGCCAATGCCACCGTTTGGCCCGTGCAGTTTACCCTTCCTCAGACCTCTGATGAATGGCTTGGGCGGACCTAGGCCATCGAATTACGACGTACTAGCCAGACCGCCGCTCGGCGGCTTTCCCGGCGTGAAGCCCTTTCAAGAGTCGGTGATACCGCCACACCAGCCAAGTCCCTTCGCCGGCAAAATCAAGGATCGCTACTCGTGCAAGTTCTGCGGCAAAAACTTCCCTCGCTCGGCCAACCTTACGCGTCATCTGCGCACTCACACCGGCGAGCAGCCCTACAAGTGCAAGTACTGCGAGCGCAGCTTCAGCATCTCCAGTAATCTGCAGCGTCACGTGCGCAACATCCACGACAAGCAGCGACCCTTCAAGTGCCCCATGTGCGAGCGCTGCTTCGGCCAGCAGACCAATCTCGATCGCCACTTGAAGAAGCACGAGGCCGACGACGGCAGTGGAGTCGTGTCCGTGGCCGATTCGGCCGACAGCAGCAACGAGAACGAGCGCGAGGAAACCTCCACGTACTTTGATGAGATTCGCTCGTTCATGGGCAAGGTGACTTATGGCAGCGACATGGCTTATGGGCTGCCGCCTCGCCACCCGGCTTACCTTCCTAGTCGCCTGCACGAGGCTCACGACTTGATGGCTGGGCCCAAAGCCAAGTACGACGAAGACGAGGACAGTGACGAAATGGTTTCGTCCTCGCTAGCCGGTAAGGAATCGCCACCGTCGCAGTTTGATCTCAAATTGAGCGGCAAGCGAGAACTGCTCAACAACAACACCGCTGAGCCAGTCATTGAAATTTCCACATAG
Protein Sequence: MACLDLSTSAMVDYKSSGSSDEGETAGGSGGGESAEMEENSSLRSSSSNSNGPAGQVDLYGASNEHHHHMPDTTSNSKRCLDVFRETSYSPPRLRHLPPSNAVAAAAAAAAALQHPHQPTYKRPFEDYPLVAWDFSEKHALETRKYFKRDYDDEQLNAIKREPVSAKNHLSPDWSIPVPDNVEISHSSSGNQYVRACKEIAEGTRFGPHQDNWYNTDFTPSNASEVLYAWKLARESFEESRDWMKFIRITINPDEANARKVKDKDGNTYLEAIRNISAKEELVSYIEPYSHHQRRITNEDENTSEYASQHSGASHADEDRDDDDDGETRCTVCDKPFQDIEILNNHLVNCHRYPDREHCCTSCSSGYAWRPLLIRHRALVHGDVRKYPCENCTKPDHPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHTKCQLKITCNKCKAQFNTITSLSKHKRFCDSTATLPPTSSSAAVAASAAALAANMPQPQPNPFLFPRQPLPFYPPSLMKYYSANLFRGTTDNLLGFPMLYPPKPDDLDRASIEGTMGSDSPKASRERFTPPRAAPPPPQASTIQQPQPVPQKVSPTSAEEATSNLRPSPARPPAPRSEESNSPRQGSSQQHKSKPRQSSVEPEPENHHHHHQQQQQNSEQPLDLCVRNKRQLPVESPISSLAPTEPEREPTPKRRRSEYSEESPNQTNSRPSSRVKSVERQSLERAPSENKEISSSPLPRSSSQVQPAESQSASERTPTPPPPPPPHMAYPRPIHPLFLESMYRNSSAAFPSFPAVGGVSGSSNSADHRLLQPMPPFGPCSLPFLRPLMNGLGGPRPSNYDVLARPPLGGFPGVKPFQESVIPPHQPSPFAGKIKDRYSCKFCGKNFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPMCERCFGQQTNLDRHLKKHEADDGSGVVSVADSADSSNENEREETSTYFDEIRSFMGKVTYGSDMAYGLPPRHPAYLPSRLHEAHDLMAGPKAKYDEDEDSDEMVSSSLAGKESPPSQFDLKLSGKRELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -