Basic Information

Gene Symbol
-
Assembly
GCA_035047105.1
Location
JAWWMK010000008.1:1990520-1993396[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.064 10 7.9 0.4 6 21 12 27 6 28 0.85
2 14 7.2 1.2e+03 1.5 0.0 2 20 34 52 33 53 0.87
3 14 1.2 1.9e+02 3.9 2.2 1 21 224 241 224 245 0.68
4 14 5.2 8.5e+02 1.9 1.8 1 19 369 387 369 389 0.94
5 14 4.5e-05 0.0074 17.8 2.7 2 23 395 416 395 416 0.98
6 14 0.005 0.81 11.4 2.5 1 23 428 450 428 450 0.95
7 14 0.31 50 5.8 0.1 1 10 470 479 470 491 0.80
8 14 0.018 2.9 9.7 0.3 3 23 498 518 496 518 0.92
9 14 5.3e-05 0.0086 17.6 4.8 1 23 571 593 571 593 0.99
10 14 2.2e-06 0.00035 22.0 3.9 1 23 599 621 599 621 0.97
11 14 0.00014 0.023 16.3 4.6 1 23 627 649 627 649 0.98
12 14 1.6e-06 0.00026 22.4 0.8 1 23 655 677 655 677 0.98
13 14 7.1e-05 0.012 17.2 0.5 1 23 681 703 681 703 0.99
14 14 0.00011 0.017 16.7 0.2 1 23 711 733 711 733 0.97

Sequence Information

Coding Sequence
ATGGGTTCGATAAGTTTAATGTGCCCCATGTGCTGTCAAGAGACTTTTAGCAACTTGGAATCACTCAAGGACCATTTGCTTAGTGTAACAAATAATCTCTATTGCCCTGGATGCTCTGAACATATTCCTTCAGTGCCTGCGTTGATTCAACATTTGGATTGTTGTGGAACAACATTCAgccaagaagaaaaacaacatgCGCAGTTGGAGTGCGATAGTTTAGTAActagtgaaaatgaaaaagtaccAGATATTTTGATGGAGGGTGCTGAAGATGAACTAAATGACAGCTTTTTAGCTACAGTCAATGAAGATGGAGTTATGATTATCGGTGAAGGAAGAACAATACAAGTAGATGAAAATGgtGATATTCAAGTCGTGGAAAAATCAAGTTCCGCAAATGCAATATCCCATTCTAAAGAGGCTATGATGAATCACGTAGAAGATGATACAGAAATTGGTGTATCTTCCGATCCAACAAATCAAAAAGAGCAGATACATTCTGCAAAACAAGAAGTATCCATGCCCAATATATCAGATGATTCAGAAATGTTTGACGATAACGAGCAAACTTACATACAATTTTCGGAAATGGATGATATGGAGCTTGAAGAAGAGTCTAGAGAAGAAACAGAAAATGTTGAAGATCAgGGAGACGGAGATGTTATGTTCAGTTGCAGTGCATGTGGAATAAGTTTTACCAATGTAAAGGACCACTTGAGGGATCACCATCACGGAGAGGAAGTAGTGTTAGAAATGAACGAGCAACAGTTGAATGAAATAGAAACATCTACTTCAAAGCCATCGTTGCCGTCTACTCGTATTACAAATACAAACGCAGGCACGTCGTCAAAAGTGTCACCAACAAACATTATCAGACCAGCTCTAAGACAGAGGCAATCGATGAACACATTGAGAACTGAAGAGTGCATCGACAGTGACGGGAGGACGTTTACCCGAAAAGTTGTACAAATAGAAAGATTTTGGGATAAGTCACCAGTTACATTGTCATCGACAAAAGCTCCAAtgatcgaaaaatttttctccaacGTCGAGGGCGTCAAAGTCAGAGATAAGAGTATAACAGTTGCCCCGACGAAAATGTACAGATGTAATCAGTGCCTAGGACAGTTCGCCAAGTTGACCGACTTTCGCGTTCACAATTGCTTTCAAGTGACCAATCGTTGTGAGAAATGTGACTTGACCTTTAATTCGGTGAGATCATTGCACGCGCACATGAGGACTCATCGGGAGGTGAACGACTATCCTCctctaaaaattttcttgtgtCAAATTTGCGGAACCGAGTTTTTGACGCACAAAAGCTTACAACTGCACAGGAGGATGCATCAGCCGGTCAAGTCGCGTCACGTCGACGCTCCCGAGGGCACGGTCGAGGAGGATAAATTCGAGTGTACCGAATGCgGAAAAGTTCTCGCAGAAGCGTACAGAGGAGCGCACATGGCCACGCACGAAGGCGACTCGATCACTTGTATTATTTGCAATCGGAAATTCGATTCCGAGCAGAGCTTGCAAATGCACAGGGCAGTTCATGCCGATTTAATTGTCGATCCTTTGCACGGATCGTCCAATGATATTATAATCCCTGATATACAAGATCCCGTAGAGCCGATATTGGATGGCAATACCTCGGCAAGTGAAATAGTTAGCAGCGAGAGAGCAGACGAAGAGATTGCCATTCAAAAGCCTTATCAGTGTCAGCACTGCGGTCGTAGATTCACGAGACCTCACGAGAAAGTTAAGCACGAGAGGATACACACAGGAGAGAAGCCGCATATTTGCGAGGTCTGTGGTAAAACATTCCGAGTGTCCTATTGCTTAACTCTCCACATGCGTACTCACACCGGTGTCCGACCGTACGAGTGTCAGCATTGTGGCAAGCGTTTCAAGGCATCCTCCGTGTACAACCATCACCTTCTGACTCACGGCGACGAGCGCGCTTACACCTGTCCGTACTGCCCGAAAACATTCAAGACTCGGGTGCAGCTGGCCGGTCACAAGAACAGCCACACCAAGCCATTCCGCTGCACCGAGTGCTCGCGACCGTTCGCCTCGCTCTACGCGGCTCGCTCGCACATGCAGACTCACAAGAAGGacaacaatttgaaattcagcTGCAACATCTGTGGCGCCTCGTACGGACGAGCTTTCGCTTTAAAGGATCATCTGAAGCAGCACGAAAACGACCATTCGGCTACGTTACCACCGGAGGCCGCGAGAGAAGAGGAAGTACAAGTGGATTTCTTGCTgcaagacgacgacgaggtcGTTGGCGATGAGCTGATTGTGCCCTCGCCGCCTCCACCTCCGTGCGAACCGATAGAGAGTGTCGAACTGATCGAGTAA
Protein Sequence
MGSISLMCPMCCQETFSNLESLKDHLLSVTNNLYCPGCSEHIPSVPALIQHLDCCGTTFSQEEKQHAQLECDSLVTSENEKVPDILMEGAEDELNDSFLATVNEDGVMIIGEGRTIQVDENGDIQVVEKSSSANAISHSKEAMMNHVEDDTEIGVSSDPTNQKEQIHSAKQEVSMPNISDDSEMFDDNEQTYIQFSEMDDMELEEESREETENVEDQGDGDVMFSCSACGISFTNVKDHLRDHHHGEEVVLEMNEQQLNEIETSTSKPSLPSTRITNTNAGTSSKVSPTNIIRPALRQRQSMNTLRTEECIDSDGRTFTRKVVQIERFWDKSPVTLSSTKAPMIEKFFSNVEGVKVRDKSITVAPTKMYRCNQCLGQFAKLTDFRVHNCFQVTNRCEKCDLTFNSVRSLHAHMRTHREVNDYPPLKIFLCQICGTEFLTHKSLQLHRRMHQPVKSRHVDAPEGTVEEDKFECTECGKVLAEAYRGAHMATHEGDSITCIICNRKFDSEQSLQMHRAVHADLIVDPLHGSSNDIIIPDIQDPVEPILDGNTSASEIVSSERADEEIAIQKPYQCQHCGRRFTRPHEKVKHERIHTGEKPHICEVCGKTFRVSYCLTLHMRTHTGVRPYECQHCGKRFKASSVYNHHLLTHGDERAYTCPYCPKTFKTRVQLAGHKNSHTKPFRCTECSRPFASLYAARSHMQTHKKDNNLKFSCNICGASYGRAFALKDHLKQHENDHSATLPPEAAREEEVQVDFLLQDDDEVVGDELIVPSPPPPPCEPIESVELIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00326575;
90% Identity
-
80% Identity
-