Gnig004742.1
Basic Information
- Insect
- Galeopsomyia nigrocyanea
- Gene Symbol
- ZEB2
- Assembly
- GCA_035047105.1
- Location
- JAWWMK010000021.1:8469980-8471904[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 14 0.0022 0.36 12.5 0.8 3 23 15 36 14 36 0.96 2 14 4.5e-05 0.0074 17.8 0.8 1 23 48 71 48 71 0.94 3 14 2.8e-05 0.0045 18.5 1.4 2 23 88 109 87 109 0.96 4 14 0.0003 0.049 15.2 0.1 1 23 115 137 115 137 0.97 5 14 0.0027 0.44 12.2 0.6 1 23 143 166 143 166 0.94 6 14 0.035 5.6 8.8 9.7 1 23 307 330 307 330 0.97 7 14 0.0015 0.25 13.0 1.2 3 23 338 358 336 358 0.92 8 14 0.0085 1.4 10.7 7.1 1 23 367 390 367 390 0.96 9 14 0.0014 0.23 13.2 3.1 1 23 396 418 396 418 0.95 10 14 2.6e-06 0.00042 21.7 1.3 1 23 423 446 423 446 0.96 11 14 0.00063 0.1 14.2 1.5 1 23 452 475 452 475 0.97 12 14 0.00059 0.096 14.3 3.8 1 23 479 502 479 502 0.97 13 14 0.00053 0.086 14.5 1.7 1 23 508 530 508 530 0.97 14 14 6.1e-05 0.01 17.4 1.3 1 23 536 559 536 559 0.95
Sequence Information
- Coding Sequence
- ATGCACGGcgaagagaggaaaaagagaCGTGTAAAACTGCTTTGCGACGCATGCGAAAGAGGATTTTCTTCCAAGTTGCAGCTGTTGAGACATCTGAAAAAATCGCACTCGGATCAGTTTAACGATGACGTCAGAGTGTGTTACGATTGCCACGTTTGCCAGAGAGTTTTCACGAGTGTCGATGCACTGAAGACTCACCTTCTCGAGCGGcacatcaacaacaacagcagcagcaacagcaacagcaacaacgaCAAGCTCACTTGCAAAGAGTGTGGAAAAATGATTTCTAGCAGTGACCATATGAAAAAGCACCTGCTGGTACACACTGGTGAACGGCCGTACAGTTGCCCGGATTGCGGCCAAGCTTTCGCTCTTCGCAACACCATGCGGGttcacgctctctctcactacgGCATCAAACCGTACGCGTGCTATCTCTGCAAATTACGCTACTCGCAGAGGTCGGCGCTGATGATGCACTGGAAAGCGAAGCACAAGACTCTTCCGGCGCCACCGCCTATCCAGATACATCAATACTTTGACCGTCACGGCAAGGTGCAGCAGCAATTTCTCAAAACAAACTTTATTAACGAGTACTGCAATAATTTGTGTTTTAGGTCAAGGTCGTCGCGACGCATCAGCGGCAAAAGCCCGGGACGAGTGCTGGTAACGGCTCGAGAACTTTACGATCCGTATGACAACCTTCCgaagcggcggtggcggcggcgtctCGGCGTGAGCAGCGGCAGTGGCAGCGGGAGAATAGCCCTCGAGAAGTATGCTGAAGTCAAAGCGGTCGAGATCGTCGACGTCAGCGAAGAAAATCCACCTGTAATCAAACAAGAGCCAAAGCAgcccggcggcggcggcggcggcaaagATAAGTTGCCGTTCAGGAAGATCCGCGGCGGTGGTTTCCGTTGCCAAATCTGCACCCAAACGTTCAGTCATTGCCACAAAGTGAAGCAGCACATCAAACAGAAGCACGGACCGTCGAAGCTGTTCGGCTGCGAGGCGTGCGGCAAGAGCTTCAAGTCCAAATACCTGTTCAACATGCACTCGACGCAGCATCTCGAGAACAGCTCGGATTATCTGTTCTGCTGCGACAAATGCGACTACCGCGCGAAAAGCAAGCACTACCTGAAGACCCACATGATCCGCAAGCACACCGAGGACTACAAGTTCGACTGCGATCACTGCAACAAGCGCTTCAAGGTGAAGGAGGACCTGAAGTTCCATCTGGGCACTCACAGCGTGCCGCAGCACATGTGCGACATCTGCGGACGTATGTACAGCAGTCGCGACTCCCTCGTCAAGCATCGCCGGGTTCAGCACGTCAACCAGTACAATTATCGCTGCGAGATCTGCAATCAGAAGCTGCGCACCCGCGAGACTTACGAGGCTCACAAGAGGAACAATCATCAGGAGGAGTTCAGCTGCGACCAGTGCGATCTCAAGTTCAAGAAGAAGTATTACGTCACCAGGCACAAGAAACGCGTGCACAAAGTCGACAAAAGCCACGTGTGCTCGGTCTGCGGTAAAGCTTTCGTCTGCACGTCCACCCTCAGAGTTCACCAGTTGATACACGCCAAAGTCAAGCCGTACTTGTGCAACGTTTGCGGCTTCAGCTTCACTCAGAGGTCCTCCATGATGCTTCACTGGAAGCGGAAGCATCCCGAGGAGACAGTACCGCCACCTCCGGTTTTACTCACCAATATCATCGATTCGATCAATTAA
- Protein Sequence
- MHGEERKKRRVKLLCDACERGFSSKLQLLRHLKKSHSDQFNDDVRVCYDCHVCQRVFTSVDALKTHLLERHINNNSSSNSNSNNDKLTCKECGKMISSSDHMKKHLLVHTGERPYSCPDCGQAFALRNTMRVHALSHYGIKPYACYLCKLRYSQRSALMMHWKAKHKTLPAPPPIQIHQYFDRHGKVQQQFLKTNFINEYCNNLCFRSRSSRRISGKSPGRVLVTARELYDPYDNLPKRRWRRRLGVSSGSGSGRIALEKYAEVKAVEIVDVSEENPPVIKQEPKQPGGGGGGKDKLPFRKIRGGGFRCQICTQTFSHCHKVKQHIKQKHGPSKLFGCEACGKSFKSKYLFNMHSTQHLENSSDYLFCCDKCDYRAKSKHYLKTHMIRKHTEDYKFDCDHCNKRFKVKEDLKFHLGTHSVPQHMCDICGRMYSSRDSLVKHRRVQHVNQYNYRCEICNQKLRTRETYEAHKRNNHQEEFSCDQCDLKFKKKYYVTRHKKRVHKVDKSHVCSVCGKAFVCTSTLRVHQLIHAKVKPYLCNVCGFSFTQRSSMMLHWKRKHPEETVPPPPVLLTNIIDSIN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -