Basic Information

Insect: Galeopsomyia nigrocyanea
Gene Symbol: ZNF217
Assembly: GCA_035047105.1
Location: JAWWMK010043724.1:2859-9033[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 0.047 7.7 8.3 0.8 1 23 300 323 300 323 0.97

2 20 0.0002 0.032 15.8 0.1 5 23 357 376 354 376 0.94

3 20 1.3 2.2e+02 3.8 1.0 3 23 384 404 384 404 0.98

4 20 3.1e-05 0.0051 18.3 0.9 1 23 410 432 410 432 0.97

5 20 2.3 3.7e+02 3.1 0.2 1 23 454 477 454 477 0.87

6 20 4.1e-06 0.00067 21.1 1.8 1 23 488 510 488 510 0.98

7 20 0.0074 1.2 10.9 0.4 1 23 547 571 547 571 0.96

8 20 0.00011 0.017 16.7 0.3 2 23 578 600 577 600 0.91

9 20 0.0014 0.22 13.2 0.2 1 23 606 628 606 628 0.98

10 20 2.5e-05 0.004 18.7 0.4 1 23 634 656 634 656 0.98

11 20 1.9 3e+02 3.3 3.2 1 19 662 680 662 685 0.78

12 20 0.00011 0.017 16.7 0.8 1 23 691 713 691 713 0.97

13 20 0.0003 0.049 15.3 2.1 1 23 720 743 720 743 0.97

14 20 2e-05 0.0033 18.9 3.3 1 23 889 911 889 911 0.97

15 20 0.001 0.17 13.6 4.1 1 23 917 940 917 940 0.96

16 20 0.00021 0.034 15.8 1.6 1 23 946 968 946 968 0.96

17 20 3.1e-06 0.0005 21.5 0.5 1 23 974 996 974 996 0.97

18 20 0.0079 1.3 10.8 2.0 1 23 1002 1024 1002 1024 0.97

19 20 1.4e-05 0.0023 19.4 1.5 1 23 1030 1052 1030 1052 0.97

20 20 4.6e-05 0.0074 17.8 2.8 1 23 1058 1081 1058 1081 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	0.047	7.7	8.3	0.8	1	23	300	323	300	323	0.97
2	20	0.0002	0.032	15.8	0.1	5	23	357	376	354	376	0.94
3	20	1.3	2.2e+02	3.8	1.0	3	23	384	404	384	404	0.98
4	20	3.1e-05	0.0051	18.3	0.9	1	23	410	432	410	432	0.97
5	20	2.3	3.7e+02	3.1	0.2	1	23	454	477	454	477	0.87
6	20	4.1e-06	0.00067	21.1	1.8	1	23	488	510	488	510	0.98
7	20	0.0074	1.2	10.9	0.4	1	23	547	571	547	571	0.96
8	20	0.00011	0.017	16.7	0.3	2	23	578	600	577	600	0.91
9	20	0.0014	0.22	13.2	0.2	1	23	606	628	606	628	0.98
10	20	2.5e-05	0.004	18.7	0.4	1	23	634	656	634	656	0.98
11	20	1.9	3e+02	3.3	3.2	1	19	662	680	662	685	0.78
12	20	0.00011	0.017	16.7	0.8	1	23	691	713	691	713	0.97
13	20	0.0003	0.049	15.3	2.1	1	23	720	743	720	743	0.97
14	20	2e-05	0.0033	18.9	3.3	1	23	889	911	889	911	0.97
15	20	0.001	0.17	13.6	4.1	1	23	917	940	917	940	0.96
16	20	0.00021	0.034	15.8	1.6	1	23	946	968	946	968	0.96
17	20	3.1e-06	0.0005	21.5	0.5	1	23	974	996	974	996	0.97
18	20	0.0079	1.3	10.8	2.0	1	23	1002	1024	1002	1024	0.97
19	20	1.4e-05	0.0023	19.4	1.5	1	23	1030	1052	1030	1052	0.97
20	20	4.6e-05	0.0074	17.8	2.8	1	23	1058	1081	1058	1081	0.98

Sequence Information

Coding Sequence: ATGGAGCAGGTCAAGGGAGAGAAAATACAAGTGGTGGTAAAAAGCGTAAATAGCAATGGAATATTGCTTGAAAATGCTAAAGGAATAAGTTTGAAAGAAGATGAAATCAAAGCAACCgaatactttttaaaagttGAAGAGCAAGATCCAAATGGTGATATTCAGCAAACTCAATACGTAGCTATAGAAAATGAGGGCGAAGAATCTCAAGATGTTGAATCTCAATTTGTACCATTGGAGGTGGATGATGTTGGTCAAATAATATTACAAGACAAAGATGTGATTCTCTGGGATGAGCTGTGTAGGATATGTGCCAATACATGTGACAAAGTAGTTCCAATATTTTCTGGTGAAGGATTGAAACATAACCTGtgcaagaaaattgaaagttatttgCCATTCAACgTTTCCGAGGATGATACACTCCCACTTCAAGTGTGTTATAATTGTGCAGCAACATTGTTAGCTTGGCATGAGATGACCCAAAATTGTCTCAATGCTCAGCAACATCTCATAGAACTACAAAGCAAACTAAACTCCAAAAGCCAGGAGCAAAATAATGTCAGTGAAGGTGAAGAGGAAGAAATCATTGACAATGGAATGGAAATGGAAGCTAGCAGTAATCAAGAAGATCAAGTGCAAGTTGAAGCTGAGGAGGAAAATGCAGTAGAGACTATGCAGATTATTAGCGAGTCAGAAATAGACAGaTCATGCGTACTGGAAGACACGCTGGTGATCCAGGTGCTGACGAGTAAGCGAGTAGTATCGAAAGCCAAGGGCAAGTCGCAAAAAATGCACGCGGGTCAAGTTAGAGCGAAGGGTCTTACTGTCCACGCGTTCGAACAGACCAAAGGAGAAGAGCGTCCAAGGGAGATATGGATCAACGGAGTAAGATGCTACGCGTGCCCAAAATGTTCGCAAATCAGCACAACGCCTTACACTCACGCAACTCACATGAGATCCGTTCACTCGAGTCGCAAGTCAACCTCATCAGCAGCAACGGGCTCCACGaaaccgcagcagcagcagcgcaaaTGGCTTTGCGAGCACACGCTGTCTGGCGGGCAAAAGTGCAGCAAAGAATTCACCACCGCCTCGTCGTTGAAGAGGCACGTGCGCGAGGTACACCTGAAGCTCAAGCAATGGGGCTGCAGCTACTGCTCGCGCAAGCTCGCCTCGAGAGAGTCGCGCGACGAGCACGAGCGCACCCACACCAACGAGCGCCCCTACGAGTGCGAGGCTTGCGGCAAGAGGTTCCGCCAGCGAGCCTCGCTGTCCGTGCACAAGCGCTTCCACAGCCGCCTCGTCAGCTTCGAAACcgagcagccgcagcagcagcagcagggagACACTCACAGCTACATGTGCGGATTGTGCGAGCAGCTCTACCAGTGGGAGAACGACTTGATGAAACACTTGCGCTCGGATCATCGAGATGAAACCAAGGGAGTGGGTGTGCGCTACGAGTGCAACACCTGCGACAAATCTTACGCGTCCAAGCGCAAATTGGTCAAGCACATGAGTCGTCACGAGAGCTGTTGTAACAAGGAAACGCGAATGCGAAAGAGCATGTATCAAGGAGAGGAGCAGGTGATGGAGAGCAGCAAGGTGTTCGATCAGCAAACTCACAAGCTACAGTTCGTCTGTCGACTGGAGGATTGCAAGGCTGTGCTGAAGAGTCGGCGTGGATTTCTTAGACACATGCGCATTCACGAGGACGCCCGACCGATCGTCTGCGAGTACTGCGGCAAATGCTATCGCATCGAGGAAGACCTCAAGCGACACATCGACGACGTTCATCGCAAAATTAAGAGATTCCAGTGTGACATTTGCGGCCGGTTCTTCGCGGCCAAAGGGACCCGCGATGCTCATCGCCGCATCCACACTGAGGAGAAACCTTTCCCGTGTCCCGAGTGCGGCAAGCACTTCCGCTCGGTCAATCTGCTGGGCATACATCGGCGAATCCACAAGGATCTTCGGCCTTTCAAATGCTCCTTCTGCCCGATGGCCTTCCGCGAGAAACAAAAGTGCCAACATCACGAGGCGGCCATTCACACCAAGGACAAGCCTCACGTGTGCGACCAGTGCGATCGCAAATTTGCCGCCAAGGGTGAACTCAATCGACATCGTAGCGTCCATTTCCCAGAGCAAAAACCCTACATGTGCTCTGTGTGTAATTACGGTTTCAGGCTTAGCCGTTACCTGCGTACCCATATCAAACGTTATCATAGCGAGGAGGCCGAGACCATGCTTAAAGGCCTGAAACGCCTCCGTCACGATAGTGTTACCTCGAAAGATGATGTGTCAAAGTCTAGTACAGCTCGCAGCAGTGCCGGCAGTTTCAAAGATTTTCGGAAACGTTACAAGCCCAGCGTGCAAGCCAACACTCGTCAAAATACAACGAAAGCTCGAGCGAAAGCGACGAGCAGCAGATCTTCCAGCAGAGTCTCGAAAATCAAAGCAAAAGCAGTGTTGAGTGAGCAGGCATCGCAAGATGACTCTTCAGTagtcaaaaaagaagaaaagtcagacgatgatgatgatgacgacgacgactttaaggttgaaataaaagagaaattaaAGGATGAAAGCTCAACAACGAAATCCTCGTCGGGCAGTAAACGACcgcgaaagaaacaaaagctTGCGAGTCCCAAGAATCACGAGTGCAAGCAGTGTGGCAAAGCTTTTCGACAGCGCAAGAGCTACGATATTCACATGCGCCAGCACACTGGTGAAAAGCCATTCACTTGTCACATTTGCGGCAAGCAGTTTGGTCAAACGGGCAGCCTTTACTATCACCTTAAACACTTGCATGGTGGAGTAAAAAATCATGCATGTGATATTTGTGGGCGCTGTTTTGCCATGAAAACTGCCATGGAAGATCATCGTAGAATTCATACTGGGGAGAGACCCTACATTTGCGACGTTTGTGGCAAGACCTTCAAGACTAAAGCTTCGCTGTATATACATAGCAAAATACATACCGATGAATATCCTTTCAATTGCTCCTACTGCAAAAAGCCATTCAGATGGAAGCAGCAAATGATTAGCCATCTGACCACTCACAcaggagagaaaaatcataTATGCGAAATTTGCAACAAAGGCTTTGGCGTCAAAAATGAACTTACAAGACATCGGCGTACTCACTCAACCGACAAACCATTCACGTGCCAGAAATGTGGGCTGAGCTTTGGACAAAAGAGATATCTTACTAACCACAGCCGGACCAGGCACAAAGTCAAACCACCGAGTGCtacttaa
Protein Sequence: MEQVKGEKIQVVVKSVNSNGILLENAKGISLKEDEIKATEYFLKVEEQDPNGDIQQTQYVAIENEGEESQDVESQFVPLEVDDVGQIILQDKDVILWDELCRICANTCDKVVPIFSGEGLKHNLCKKIESYLPFNVSEDDTLPLQVCYNCAATLLAWHEMTQNCLNAQQHLIELQSKLNSKSQEQNNVSEGEEEEIIDNGMEMEASSNQEDQVQVEAEEENAVETMQIISESEIDRSCVLEDTLVIQVLTSKRVVSKAKGKSQKMHAGQVRAKGLTVHAFEQTKGEERPREIWINGVRCYACPKCSQISTTPYTHATHMRSVHSSRKSTSSAATGSTKPQQQQRKWLCEHTLSGGQKCSKEFTTASSLKRHVREVHLKLKQWGCSYCSRKLASRESRDEHERTHTNERPYECEACGKRFRQRASLSVHKRFHSRLVSFETEQPQQQQQGDTHSYMCGLCEQLYQWENDLMKHLRSDHRDETKGVGVRYECNTCDKSYASKRKLVKHMSRHESCCNKETRMRKSMYQGEEQVMESSKVFDQQTHKLQFVCRLEDCKAVLKSRRGFLRHMRIHEDARPIVCEYCGKCYRIEEDLKRHIDDVHRKIKRFQCDICGRFFAAKGTRDAHRRIHTEEKPFPCPECGKHFRSVNLLGIHRRIHKDLRPFKCSFCPMAFREKQKCQHHEAAIHTKDKPHVCDQCDRKFAAKGELNRHRSVHFPEQKPYMCSVCNYGFRLSRYLRTHIKRYHSEEAETMLKGLKRLRHDSVTSKDDVSKSSTARSSAGSFKDFRKRYKPSVQANTRQNTTKARAKATSSRSSSRVSKIKAKAVLSEQASQDDSSVVKKEEKSDDDDDDDDDFKVEIKEKLKDESSTTKSSSGSKRPRKKQKLASPKNHECKQCGKAFRQRKSYDIHMRQHTGEKPFTCHICGKQFGQTGSLYYHLKHLHGGVKNHACDICGRCFAMKTAMEDHRRIHTGERPYICDVCGKTFKTKASLYIHSKIHTDEYPFNCSYCKKPFRWKQQMISHLTTHTGEKNHICEICNKGFGVKNELTRHRRTHSTDKPFTCQKCGLSFGQKRYLTNHSRTRHKVKPPSAT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -