Basic Information

Insect: Galeopsomyia nigrocyanea
Gene Symbol: -
Assembly: GCA_035047105.1
Location: JAWWMK010000032.1:10229768-10232658[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.001 0.17 13.6 0.1 1 21 61 81 61 82 0.95

2 13 1.9e-06 0.00031 22.2 1.3 1 23 173 196 173 196 0.96

3 13 0.00048 0.078 14.6 2.7 2 23 203 225 202 225 0.95

4 13 3.3e-05 0.0053 18.3 4.0 1 21 232 252 232 253 0.95

5 13 1.5e-08 2.4e-06 28.8 1.8 1 23 264 286 264 286 0.98

6 13 1.4e-05 0.0023 19.4 1.0 2 23 296 317 295 317 0.97

7 13 0.016 2.6 9.8 0.4 2 23 324 345 323 345 0.96

8 13 1.5e-06 0.00024 22.5 2.5 1 23 351 373 351 373 0.99

9 13 1.7e-05 0.0028 19.2 2.6 1 23 379 401 379 401 0.95

10 13 1.1e-05 0.0017 19.8 1.4 1 23 407 430 407 430 0.94

11 13 3.4e-08 5.5e-06 27.7 2.5 1 23 436 458 436 458 0.98

12 13 1.3e-06 0.00021 22.7 3.4 1 23 464 486 464 486 0.98

13 13 7.3e-06 0.0012 20.3 0.9 2 23 493 515 492 515 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.001	0.17	13.6	0.1	1	21	61	81	61	82	0.95
2	13	1.9e-06	0.00031	22.2	1.3	1	23	173	196	173	196	0.96
3	13	0.00048	0.078	14.6	2.7	2	23	203	225	202	225	0.95
4	13	3.3e-05	0.0053	18.3	4.0	1	21	232	252	232	253	0.95
5	13	1.5e-08	2.4e-06	28.8	1.8	1	23	264	286	264	286	0.98
6	13	1.4e-05	0.0023	19.4	1.0	2	23	296	317	295	317	0.97
7	13	0.016	2.6	9.8	0.4	2	23	324	345	323	345	0.96
8	13	1.5e-06	0.00024	22.5	2.5	1	23	351	373	351	373	0.99
9	13	1.7e-05	0.0028	19.2	2.6	1	23	379	401	379	401	0.95
10	13	1.1e-05	0.0017	19.8	1.4	1	23	407	430	407	430	0.94
11	13	3.4e-08	5.5e-06	27.7	2.5	1	23	436	458	436	458	0.98
12	13	1.3e-06	0.00021	22.7	3.4	1	23	464	486	464	486	0.98
13	13	7.3e-06	0.0012	20.3	0.9	2	23	493	515	492	515	0.95

Sequence Information

Coding Sequence: atGGGGGAAGTTATAGaaattttaaaagtggAGAATACTTATTTGGCACATGATGAGATGAGTGAAGTCGTTGCTGACTTGTTGGTTAAAGACTCGGATCAAGGTACACTCATCATACCTGACATGATAGACTCGGACGTTCTCACACAAAATGGACAAATTATTCAGATTATTGGAGAATACGAGTGTGTTACTTGTCACCGTATATTTCCAAGTGAAGACatgcTGAAAGAGCACTTGCAAGTGTGTAGAGAGGAAGACGATGATGCAGAGTTCTTAGAATTAGGCAGGATGGAGGACATAGAGTccgaagaggaagaagaagaagaagaagaagaaggggagGAAGAAAATGAGTACAAAATAGATGACCCAGACTACATTACTGAAAATTCAAACCTTTCAGATTctcaaaatgtaaaaaataataaccaaaAACCAGCAATCAAACCAGTATCGGAAGGCCAATGTCATTGCTGTGCTGAAGATGCAAAGACTGCTCACTCTGGTGGTCCTTTCAAATGTTCACATTGTGATTTATCGTTTAAAAAATCAGCTTCTCTGGAGAGGCATTTAATAGTTATTCATTGGGAAGCTGATACATGCATATGTGAATATTGCAATGCTTCTTTTCGAGATAAAAAGGCTTTGGACAAGCATCGCTACACCACGCatatgaaaacaaataaagtaTACAAATGTGATAAATGTGATACTTATTTTTCGAGAAGCTATCATTTAAATCGACATAAGCAGCAGTCGGGATGTCACGGAGATACTGCAAATACTTTTTCATGCCAGgTTTGCAACAAAGTATTCACGCGCAAAGATAATCTGAGGGAACACTTGAGAACCCATGCAGGAATgccgcaaagaaaaaagaaatcttgtAATCTTTGCCCgaaacaattttatacaaatcaGCAGTTAATTATACATCAACGAATGCACACTGGCGAGAGACCAATCGAATGTGATTTATGCCCCAAGACGTTTTTGTCAACTTTAGCCATGAAAAAGCACAGAAGAGTTCATACCGGAGAGAAACCTTTTGAATGCAAATATTGCCAGAAAAAATTTGCTGCAAGAGAAACTTTGAATCGTCATCAAAGAACTCATACTGGAGAAAAGCCTCATATTTGTCAATACTGCAACAAATCCTTCATTCAAGCAGCTCAACTCAGAGCACACATCTTCCATCATACTGGAGAAAATGGCTTTTATTGCGATATTTGCGGCAAGGCTTTCAATAGAAAGGCACGTTTGACTAATCACAAGAAATTTGTTCACGAAGGTGCTACACCTTTTAAATGTGACAAATGTGACAAGTCATTCACGCGAAAAGAAGATTTGTCCAAACACATGAATCTTCATGCTGGCattaaacCTCATAAATGCGATACTTGTGGAAAATGCTTTGCAGCAAAATCATCTTTACAAGCTCATTTGAATACCCACAGACGCGAACCGCCACAATCATGTGCCGAATGTGGTAGAGCATTTATTAGACAAGATTGTCTGATGCGTCATATTCGCGCGAAACATAGAGATCTCTTGGAAGATGTACTTGGTGAAGCAGAAAAGAAACATTTACAATTACAAATGTTTAATATTGCTTATGAAGCTGCTGAGAAGTCAAAAACAGGAGAGACCAATATTCTTTCAACAGACGAATTGATGAAAGCCATTACAGAACTTTTGACTAtacttattgaaaaagaaacgttGGACctctttgGATGGTGCCAATCACCTTTGCAAGAAGTTTTAGAAGCTGTAATTAGAAGATGTGGGCATGAACCACTCACTGCTGATAGTGATTTATCGTTGTCCGAAAGATTAAGAGGAAATGTTAAGCTTTTATTCAATGCCGTAATTGAAGATGAGAATGTTAAATCATTACTAACTGTGCAAACAGTTGATGAAGTAATTATGCACGTTCTTAAATCATCCAAAAAAGACCCAGAGGAAATAGAAGGATAA
Protein Sequence: MGEVIEILKVENTYLAHDEMSEVVADLLVKDSDQGTLIIPDMIDSDVLTQNGQIIQIIGEYECVTCHRIFPSEDMLKEHLQVCREEDDDAEFLELGRMEDIESEEEEEEEEEEGEEENEYKIDDPDYITENSNLSDSQNVKNNNQKPAIKPVSEGQCHCCAEDAKTAHSGGPFKCSHCDLSFKKSASLERHLIVIHWEADTCICEYCNASFRDKKALDKHRYTTHMKTNKVYKCDKCDTYFSRSYHLNRHKQQSGCHGDTANTFSCQVCNKVFTRKDNLREHLRTHAGMPQRKKKSCNLCPKQFYTNQQLIIHQRMHTGERPIECDLCPKTFLSTLAMKKHRRVHTGEKPFECKYCQKKFAARETLNRHQRTHTGEKPHICQYCNKSFIQAAQLRAHIFHHTGENGFYCDICGKAFNRKARLTNHKKFVHEGATPFKCDKCDKSFTRKEDLSKHMNLHAGIKPHKCDTCGKCFAAKSSLQAHLNTHRREPPQSCAECGRAFIRQDCLMRHIRAKHRDLLEDVLGEAEKKHLQLQMFNIAYEAAEKSKTGETNILSTDELMKAITELLTILIEKETLDLFGWCQSPLQEVLEAVIRRCGHEPLTADSDLSLSERLRGNVKLLFNAVIEDENVKSLLTVQTVDEVIMHVLKSSKKDPEEIEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00691361;
90% Identity: iTF_00326555;
80% Identity: -