Basic Information

Insect: Galeopsomyia nigrocyanea
Gene Symbol: BCL6B
Assembly: GCA_035047105.1
Location: JAWWMK010000006.1:72520-74388[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.22 36 6.2 0.7 2 23 104 125 103 125 0.97

2 14 1.9e-05 0.003 19.1 1.1 2 23 130 151 130 151 0.98

3 14 1.5e-05 0.0024 19.4 2.4 2 23 158 179 157 179 0.97

4 14 3.7e-07 6e-05 24.4 1.4 1 23 213 235 213 235 0.98

5 14 3e-06 0.00049 21.6 2.3 1 23 269 291 269 291 0.99

6 14 1.2e-06 0.00019 22.8 2.2 1 23 297 319 297 319 0.96

7 14 1.6e-05 0.0027 19.2 0.2 1 23 325 347 325 347 0.98

8 14 3.3e-05 0.0054 18.3 5.3 1 23 353 375 353 375 0.97

9 14 1.1e-07 1.8e-05 26.0 0.8 1 23 380 402 380 402 0.97

10 14 0.0002 0.032 15.8 0.5 1 23 408 430 408 430 0.97

11 14 1.3e-05 0.0021 19.5 6.8 1 23 436 458 436 458 0.97

12 14 2.2e-07 3.5e-05 25.1 1.0 1 23 464 486 464 486 0.99

13 14 2.3e-06 0.00037 21.9 0.6 1 23 493 515 493 515 0.98

14 14 6.7e-05 0.011 17.3 1.9 2 23 522 544 522 544 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.22	36	6.2	0.7	2	23	104	125	103	125	0.97
2	14	1.9e-05	0.003	19.1	1.1	2	23	130	151	130	151	0.98
3	14	1.5e-05	0.0024	19.4	2.4	2	23	158	179	157	179	0.97
4	14	3.7e-07	6e-05	24.4	1.4	1	23	213	235	213	235	0.98
5	14	3e-06	0.00049	21.6	2.3	1	23	269	291	269	291	0.99
6	14	1.2e-06	0.00019	22.8	2.2	1	23	297	319	297	319	0.96
7	14	1.6e-05	0.0027	19.2	0.2	1	23	325	347	325	347	0.98
8	14	3.3e-05	0.0054	18.3	5.3	1	23	353	375	353	375	0.97
9	14	1.1e-07	1.8e-05	26.0	0.8	1	23	380	402	380	402	0.97
10	14	0.0002	0.032	15.8	0.5	1	23	408	430	408	430	0.97
11	14	1.3e-05	0.0021	19.5	6.8	1	23	436	458	436	458	0.97
12	14	2.2e-07	3.5e-05	25.1	1.0	1	23	464	486	464	486	0.99
13	14	2.3e-06	0.00037	21.9	0.6	1	23	493	515	493	515	0.98
14	14	6.7e-05	0.011	17.3	1.9	2	23	522	544	522	544	0.95

Sequence Information

Coding Sequence: ATGAATCTCCAGGTTATGgatgaaaatattgtcagTGTTATACTAAAAGAAGAGCCTGGAGAGAAGTACCAATCAAGCTACATGGAAGACATTTGTTTGGGTACTTTCGAGAAAATGTTTCAATCTATGGACCACCACGAAGTTGATTTTCCAGAAGACATGGTTAAACTGGAATTTGACCCCGATAGTCCTCACCATCATTGGGCAGCTCAATTAGCAAGTGCAGCTTTGGGTGAGGGTGGGGAACATGGTGGACCAAACGATCCAAATTTCCTTGACTCAAGTGCaggacaaaaattttataaaatccaGTGTACACTTTGCAAGAAATGGTTTTTGAATAATGATTCTATGGTGACTCATTTGAAAATGCACTGTAGTGGTAACACTTGTGAAGTTTGTCATCAGACTTTTGCAGATAATGCTGGTTTGCATGCTCATATGTTAACGCATGTGGGTATGAGCCCGGTAGAGTGTACAATTTGTCAGAAGAGATTTGCTTACAAGTGGTGTTTGAGAAATCACATGCAGAGTCATATGTCGAACAAACAATTTGAATACGACAGTTTGCAACAAGCTATTCTGAAAAGATATGGACAACCTAACGATCATGGACTAAGTAACGAAGACAGGCCTTACACCTGTCAAATCTGTCAAACATCCTTCCGTGACAAAGGGAATTTCAGTCGTCACATGCTGATTCACACAGGTGAGCAACTCCATAATGCTCATTTATACTCTGCCCAATTTTACAAGATGGACCAGTTGAATAATCACGACCTAGCCCATTCAGGTTACAAGCAATACAAGTGCACCATGTGCCACCGAGCCTTTGGACAAAAAACCGCTTTGAACAATCACATGCTGTCGCACAGTGGAGAAAAGCCTCACGCCTGCAATATCTGCGAAAAAACTTACAAACGAAAGTCGGAATTGATGAGGCACACTATGATCCACACCGGCGAACGGCCGTACGAGTGTCCGGAGTGCTTGATGACTTTTCGTGAAAAGGCCAAATTGAACTCCCATATGCTGGTACATACGGGCGAAAAGCCTCACGAGTGCTACATCTGTCACAAAGCGTGCGCTCGCAAATCCGATCTAAATAGCCACATGCTTTCGCACACGGGAGGTCAATACGACTGCAAggtttgtaataaaattttcacgagGAAGTCCGATTTGAACAGGCACGTGCTGGTTCATACGGGTGAAAAGCCGTACGCGTGTCAGTACTGCAACATGGCTTTTCGAGAAAAGACAAGACTGAATTCCCACATGGTTATTCACACGGGTGACAAGAGGCACATCTGCCACATTTGTCACAAGGGTTTTCGCGAGAAATCGATGTTGAAGAAACACATGTTGAGTCACACCGGCGACAGACCCTACGAATGTTACATATGTCAGAAAGCCTTCACTCAAAGGAGTACTCTCAATAGCCACATTCTCACTCACACGACAGAGGCGTCGTCCTACGAATGCACCATTTGTAAAAAAGTCTATCGCGACAGGATGGCACTGCGAAAACATTTGATATCCCACACTgtagataaaaataacgaatgcCCCATCTGCCTGAAAAAGTTCACTCACAAGTCGGCTCTGAGTAGTCACCTGACATCGACTCATTCTTTGTAA
Protein Sequence: MNLQVMDENIVSVILKEEPGEKYQSSYMEDICLGTFEKMFQSMDHHEVDFPEDMVKLEFDPDSPHHHWAAQLASAALGEGGEHGGPNDPNFLDSSAGQKFYKIQCTLCKKWFLNNDSMVTHLKMHCSGNTCEVCHQTFADNAGLHAHMLTHVGMSPVECTICQKRFAYKWCLRNHMQSHMSNKQFEYDSLQQAILKRYGQPNDHGLSNEDRPYTCQICQTSFRDKGNFSRHMLIHTGEQLHNAHLYSAQFYKMDQLNNHDLAHSGYKQYKCTMCHRAFGQKTALNNHMLSHSGEKPHACNICEKTYKRKSELMRHTMIHTGERPYECPECLMTFREKAKLNSHMLVHTGEKPHECYICHKACARKSDLNSHMLSHTGGQYDCKVCNKIFTRKSDLNRHVLVHTGEKPYACQYCNMAFREKTRLNSHMVIHTGDKRHICHICHKGFREKSMLKKHMLSHTGDRPYECYICQKAFTQRSTLNSHILTHTTEASSYECTICKKVYRDRMALRKHLISHTVDKNNECPICLKKFTHKSALSSHLTSTHSL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01469925;
90% Identity: iTF_00326553;
80% Identity: -