Basic Information

Insect: Frieseomelitta varia
Gene Symbol: zfh1
Assembly: GCA_011392965.1
Location: WNWW01000956.1:47491-81962[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 1.7e-05 0.0011 18.6 0.6 2 23 125 146 124 146 0.97

2 6 4.1e-06 0.00025 20.5 7.8 1 23 155 177 155 177 0.99

3 6 1e-05 0.00062 19.3 1.9 1 21 183 203 183 204 0.95

4 6 0.00016 0.0098 15.5 4.5 1 23 651 673 651 673 0.94

5 6 5.1e-05 0.0032 17.1 7.1 1 23 679 701 679 701 0.98

6 6 0.0011 0.066 12.9 4.3 1 21 707 727 707 728 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	1.7e-05	0.0011	18.6	0.6	2	23	125	146	124	146	0.97
2	6	4.1e-06	0.00025	20.5	7.8	1	23	155	177	155	177	0.99
3	6	1e-05	0.00062	19.3	1.9	1	21	183	203	183	204	0.95
4	6	0.00016	0.0098	15.5	4.5	1	23	651	673	651	673	0.94
5	6	5.1e-05	0.0032	17.1	7.1	1	23	679	701	679	701	0.98
6	6	0.0011	0.066	12.9	4.3	1	21	707	727	707	728	0.96

Sequence Information

Coding Sequence: ATGAGCATGACTCTCGTCCGGAATACGTTCAAAGGTTGCAGCGAGGACGAGGCAGCAGGTGTCGTGAACGCGGAGGTGGGCGGAGGTTGCGCGACCGGGGCGCCAACCACAGGAAGTGGCGTTGGAGGTGGTAGCGGGACAGGTAGCGAGGTTGGCGATGGTGGTAGAGCAGGAGCAGGAACAGAAGGAGGcggtggtggcggcggcggcggtggtggcgAGGGCGGATCGACGAAGCAGGGTGGCGCGAGGTGTCCCCAGTGCGGCTTCCTCTGTTGGGACGTCCACGTGCTTCAGCTCCATCTCGAGAACACGCACAAGACCTCGTACGCCATCGACAAGAACGATCTCAACGCTCAATTCCCTCAAGTGTCCTGCAAGGTGTGCAGCAAGACTTTTGCTAACGTCTACCGACTCCAGAGGCACATGATCAGCCATGATGAGAGTGCCGTGCTTCGTAAGTTTAAGTGTCCCCATTGCGAGAAAGCCTTCAAGTTTAAGCATCACCTCAAGGAGCACCTTCGCATTCACAGCGGTGAAAAGCCATTCCAATGCAACAACTGCGGCAAACGCTTCTCCCATTCGGGCTCGTATTCGAGTCACATGACCTCGAAGAAGTGCCTGATAGTGAACTTAAAGAAATCCAGGCATACGAATGTGAGCAACGTGGACCGCGGGCCGAAAAAGGCGCAACAACCCCTGCCGCCGAGGCGGCGCGAGGTCGATCTGCTCGCGGCGAATAATAACACTTTCCTCCCCATTCTGCCGAAGCTTTCACCCTCGGATTATCAAGAGATACAACGGGAAGGCACGGGTATTTACGATATGCCGACGCTTCTGCCGCAAATGATGGGCCTCGGCAGCTACTTCCTGCAGACGTCCTTGGGCAAGCTCTTAAATCAGCTACATTCCAAGAGATTGGACGAGGTAGCCGAGCAAGTCGAGTCTCATCGGGAGCTTATGAGCCCGTCGACGGCGGACTCTGAGGGCACGGAGGGCACAGAGGGCAAAGAATCACCGGCGCCGACCGACTCGCAAGGCCTCGACGCGGTTCGACGTATCCTCGAAACGGTGAACACCTCCGTCACGAAGCAATTACTCGAGGCGAACGTGAGGAAATTGTCCACCTCGCCGGCCACGATGAAACGAGAGTTCGAGGAGGATTATCAAGATCAAGACAGCGAGATGTCCAGCGAGATGGCACATTATCCAGACTGGTCGGATAAATATGACTCGCAGAGCGAAGGTTTGGCGGCGAAACTCGAGGACGTGAATCAGCCCAGCGCGAAATCGGGGTACAAGAGAAAAGCGGAGGAGGTGGacgaggaggacgaggaggtggacgaggaggacgaggaggaCGGCACACAAACGCACAATGACAACGGAAGGAGAGTCAGGGCTAGATCGTTGATAGACGACGAGCAATTGGCCGTTCTCAAGGGTTACTATGCCATTAATCCTCGACCGAAGAAGGAGGAGATCATCAGGATCGCCAACTATATCAATTTTCCTACTCGTGTAGTACAGGTTTGGTTTCAAAATTCCCGAGCGAGGGACCGACGAGAATCGAAGATACCACCTCTGGTACCATTGGCAAATTCAACCAGTCAGACCGCGTACGAACAGCCATTAGATTTGTCGAAGAAAGAGGCACTCACGGACTCGGCGTGCAAAGACAATGAAACTATCTGTGTAAAGTTCACGTCGTCGTCTCCTGATGAACAGAAGAACGACAATGCGCCGTCGCATAATCAAGACGCGGATGATCTGGAAGATTCGCCGTTGATCATCGACGAGGAGACCACCGATTCTGTAGAAACGAAACGCACGGCCCCGAATGGGAGAGAAATTATTCCAAAGGGTCAACCTCAGACAAATGCAAAGAACGAAAGTGAAAACGCGAGACAACCGGAGGCTTCGCCAGCGGGGGAAATCGAGCAGGGTGTCTATTTCTGTGATCGGTGTGACAAAACATTCTCCAAGCACAGTTCCCTAGCAAGACACAAATACGAACATTCCGGGCAAAGGCCGTACAAATGCGTGGAGTGCCCAAGGGCGTTCAAACATAAGCATCATCTGACCGAACACAAGCGACTGCACAGCGGCGAAAAGCCCTTTCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTACAGCCAACACATGAATCATCGTTTCTCTTACTGCAAGCCGTATAGAGAATAG
Protein Sequence: MSMTLVRNTFKGCSEDEAAGVVNAEVGGGCATGAPTTGSGVGGGSGTGSEVGDGGRAGAGTEGGGGGGGGGGGEGGSTKQGGARCPQCGFLCWDVHVLQLHLENTHKTSYAIDKNDLNAQFPQVSCKVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRHTNVSNVDRGPKKAQQPLPPRRREVDLLAANNNTFLPILPKLSPSDYQEIQREGTGIYDMPTLLPQMMGLGSYFLQTSLGKLLNQLHSKRLDEVAEQVESHRELMSPSTADSEGTEGTEGKESPAPTDSQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKREFEEDYQDQDSEMSSEMAHYPDWSDKYDSQSEGLAAKLEDVNQPSAKSGYKRKAEEVDEEDEEVDEEDEEDGTQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIRIANYINFPTRVVQVWFQNSRARDRRESKIPPLVPLANSTSQTAYEQPLDLSKKEALTDSACKDNETICVKFTSSSPDEQKNDNAPSHNQDADDLEDSPLIIDEETTDSVETKRTAPNGREIIPKGQPQTNAKNESENARQPEASPAGEIEQGVYFCDRCDKTFSKHSSLARHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRFSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086058;
90% Identity: iTF_00982854;
80% Identity: iTF_00733858;