Basic Information

Insect: Frieseomelitta varia
Gene Symbol: fezf2
Assembly: GCA_011392965.1
Location: WNWW01000786.1:118562-119689[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 3.3e-07 2e-05 24.0 0.6 1 20 158 177 158 180 0.93

2 6 1.6e-07 9.7e-06 25.0 1.6 1 23 186 208 186 208 0.97

3 6 2.8e-08 1.8e-06 27.3 2.7 1 23 214 236 214 236 0.98

4 6 2.6e-06 0.00016 21.1 3.2 1 23 242 264 242 264 0.98

5 6 0.00031 0.019 14.6 6.0 1 23 270 292 270 292 0.99

6 6 5e-08 3.1e-06 26.5 4.5 1 23 298 321 298 321 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	3.3e-07	2e-05	24.0	0.6	1	20	158	177	158	180	0.93
2	6	1.6e-07	9.7e-06	25.0	1.6	1	23	186	208	186	208	0.97
3	6	2.8e-08	1.8e-06	27.3	2.7	1	23	214	236	214	236	0.98
4	6	2.6e-06	0.00016	21.1	3.2	1	23	242	264	242	264	0.98
5	6	0.00031	0.019	14.6	6.0	1	23	270	292	270	292	0.99
6	6	5e-08	3.1e-06	26.5	4.5	1	23	298	321	298	321	0.98

Sequence Information

Coding Sequence: ATGGCGACCGAAACACCGACCAGTCTTCCGCCAGAGAGGGTTACCTCGCCCGCACCGTGCAAGAACTTGACCTTTTCTATCGCTAAAATCATGGAGCCGGACAAACGTCTTACCGAGCAGAGCAACAATCAGCAAACCACACCGCCGCAACCTCCGCCGCCCAGTATCCCCTCGTTAACTTATTCCGCGCACTTAGAATCGGCCTTCAAGAAATACGTGCCAACGTTGAGGCATCAGAATCTCTTGCAACCCTATTCTCTTCTCTATTATCATCCGAATCCATTGCTGAGTGCCTTTCCAGCACCACCGCCCACCACGCCCACGGTTCCGCAGAATTCACCACCCCCAACCACCATTCAGAAAGCTTTCTCGAAGATGAGTCGGACAACGATCTCGTCGGACAGCCAACGCGAGAAAAAGAGTCCCGGTCCACGGAGCAACGAACTCAGCGCCACGAACAAGCAGAAAACGTTCACCTGCCCCGAATGCGGGAAGGTGTTCAACGCGCATTACAATCTGACCAGACACATGCCGGTTCACACGGGGGCGCGGCCGTTCGTTTGCAAGATCTGCGGCAAGGGCTTTCGCCAGGCGAGCACCCTGTGCAGGCACAAGATCATCCACACGGCGGAGAAGCCGCACAAGTGTCCGACCTGCGGCAAAGCTTTCAACCGGAGCTCAACCCTGAACACGCACAGACGTATCCACGCCAATTACAAGCCGTTCGTGTGCGAGTACTGCGGCAAGGGGTTCCATCAGAAGGGCAACTACAAGAATCACAAACTGACGCACAGCGGTGAAAAGGCGTACAAGTGCAACATCTGCAACAAGGCGTTCCATCAGATCTACAATCTCACCTTTCACATGCACACGCACAACGACAAGAAACCGTTCTCCTGCAAGATCTGCGGCAAAGGGTTCTGCAGGAACTTCGATCTGAAGAAACACATGAGAAAGTTACACGACACCGGGTCACCGGTGTTGAACGGCCTAGGTACTTCGGTGCAGAGTCATAATCAGCAGTCTGGATACGCGTCGGTTCACCACGGACCCGGTAGCCATTCGTTCGTCAGCCCCTTCTTGCTGCCGCCGCCCGGTACCACGAGTTATCTCAGCAAAATGTTGTGA
Protein Sequence: MATETPTSLPPERVTSPAPCKNLTFSIAKIMEPDKRLTEQSNNQQTTPPQPPPPSIPSLTYSAHLESAFKKYVPTLRHQNLLQPYSLLYYHPNPLLSAFPAPPPTTPTVPQNSPPPTTIQKAFSKMSRTTISSDSQREKKSPGPRSNELSATNKQKTFTCPECGKVFNAHYNLTRHMPVHTGARPFVCKICGKGFRQASTLCRHKIIHTAEKPHKCPTCGKAFNRSSTLNTHRRIHANYKPFVCEYCGKGFHQKGNYKNHKLTHSGEKAYKCNICNKAFHQIYNLTFHMHTHNDKKPFSCKICGKGFCRNFDLKKHMRKLHDTGSPVLNGLGTSVQSHNQQSGYASVHHGPGSHSFVSPFLLPPPGTTSYLSKML

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00360415;
90% Identity: iTF_00142626;
80% Identity: -