Basic Information

Gene Symbol
SCRT1
Assembly
GCA_033675135.1
Location
CM066259.1:10589992-10616091[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 5 1.3e-07 8.2e-06 25.0 0.6 1 23 357 379 357 379 0.98
2 5 0.00038 0.023 14.1 0.0 2 23 389 410 389 410 0.98
3 5 1e-05 0.00064 19.0 0.2 1 23 414 436 414 436 0.96
4 5 2.1e-08 1.3e-06 27.5 0.6 3 23 444 464 442 464 0.98
5 5 3.9e-05 0.0024 17.2 3.4 1 21 470 490 470 491 0.94

Sequence Information

Coding Sequence
atggtggtggtggtggtggtggtggaggtagtggtggtggtggtgatggtggtggtggtgagggtggtggtggagatggtgggggtggtggtggtggtggtggtggtggtggtggtgatggtggtggtggtggtggtggtggcggtggtggtggtggtggtggtggtggtgttggtggtggtggtgttggtggtggtggtggtggtggtggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggaggagggaggtgagttagCTGCTGGCGTCATCACGCCCATGACGACGGGCCCCTTCCTGACGTCGACAGGCTACGTCCAGGAGCTGACGGCGCTGCCCTTCACCGCCTACCTCGGCCAccacccgccgctgccgccgctctcgcccggctcgcccgcgcccacctacgccacgctgcagccgccgtcgccctcctcgtccacgccgcggcgctgcttcACCAGCACGGGCGCGCAGCTGTCGCTGCCGCCCAAGAAGAAGGACATCTACCGGCCGTACTCGCTGGAgccgtcgtcctcgccgccgccgctcgacGTGCGGGAGGAGgacccccagcagcagcagcagcggcagtacgtggaggtggcgcggcccgagccgcagcgcgcgcgccccatcACCCTCACCAtcacccccacgccgcccgtccgccccatcccgctcGACCCGCTGCGAGACTACCAGCAGCtggacgcgcggccgccgccgctcagcctgagcacggccgcgcccgacgacctgaccgccgcgcacgccatcCTCGACCTGAGCGCGTCCACCCTGCCGTACCCGCCGGCcgtgcaccaccagcagcagcaccaccacgacgagcaccagcagcagcacctccaGCCGCAGCCCAAGGCCAgccccaacaacaacaagggcTCCACCAAGACCGTCTCCTACACCTACGAGGCCTTCTTCGTGAGCGACGGCCGCTCCAAGCGCAAGTCGTCGTCCTCGGAGGACGAGGGCAACGGCGGCAACGCGCCCGACAAGAAGGGGCGGTACGCGTGCGGCGAGTGCGGCAAGCGGTACGCCACGTCCAGCAACCTGTCGCGGCACAAGCAGACGCACCGCAGCCTGGActcgggctcggcgcgccagTGCAACGTGTGCGGCAAGGCGTACGTGAGCATGCCCGCCCTGGCCATGCACGTGCTCACGCACCAGCTGACGCACGCGTGCGGCGTGTGCGGCAAGCTCTTCTCGCGGccctggctgctgcagggccaccTGCGCTCGCACACGGGCGAGAAGCCCTACGGCTGCGCGCACTGCGGCAAGGCGTTCGCCGACCGCTCCAACCTGCGCGCCCACATGCAGACCCACTCGCAGGACAAGTCGTACTCGTGCCACCGGTGTCACAAGAGCTTCGCGCTCAAGAGCTACCTCAACAAGCACCTCGAGTCGTCCTGCGTGCGAGACGGCGTCAGCTCGTCGGAGGAGTCGTCCATGACGGGGTCGGTGGAGGAGAACACCAACTCCGCCTTCGCAACACCCAACACCAGTATGGTGGGCATGCCCTTCGCCACAGCGTGCTCAGCGTGA
Protein Sequence
MVVVVVVVEVVVVVVMVVVVRVVVEMVGVVVVVVVVVVVMVVVVVVVAVVVVVVVVVLVVVVLVVVVVVVEEEEEEEEEEEEEEEEEEEEEEEEGGELAAGVITPMTTGPFLTSTGYVQELTALPFTAYLGHHPPLPPLSPGSPAPTYATLQPPSPSSSTPRRCFTSTGAQLSLPPKKKDIYRPYSLEPSSSPPPLDVREEDPQQQQQRQYVEVARPEPQRARPITLTITPTPPVRPIPLDPLRDYQQLDARPPPLSLSTAAPDDLTAAHAILDLSASTLPYPPAVHHQQQHHHDEHQQQHLQPQPKASPNNNKGSTKTVSYTYEAFFVSDGRSKRKSSSSEDEGNGGNAPDKKGRYACGECGKRYATSSNLSRHKQTHRSLDSGSARQCNVCGKAYVSMPALAMHVLTHQLTHACGVCGKLFSRPWLLQGHLRSHTGEKPYGCAHCGKAFADRSNLRAHMQTHSQDKSYSCHRCHKSFALKSYLNKHLESSCVRDGVSSSEESSMTGSVEENTNSAFATPNTSMVGMPFATACSA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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