Fexs007337.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Formica exsecta
Gene Symbol
-
Assembly
GCA_003651465.1
Location
NW:23691-135162[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.0045 0.3 11.0 0.1 2 23 147 168 146 168 0.95
2 10 0.00079 0.054 13.3 4.2 1 23 174 196 174 196 0.98
3 10 0.001 0.07 13.0 0.7 1 23 202 225 202 225 0.93
4 10 0.24 16 5.5 5.8 1 23 231 253 231 253 0.98
5 10 8.3e-08 5.6e-06 25.9 1.0 1 23 259 281 259 281 0.97
6 10 4.9e-05 0.0033 17.1 0.6 1 23 287 309 287 309 0.97
7 10 0.002 0.13 12.1 4.2 1 23 315 337 315 337 0.97
8 10 3.2e-07 2.1e-05 24.0 1.2 1 23 343 365 343 365 0.98
9 10 0.00014 0.0091 15.8 1.5 1 23 371 393 371 393 0.98
10 10 0.00023 0.016 15.0 4.4 1 23 399 422 399 422 0.98

Sequence Information

Coding Sequence
ATGGTTTTGAATGGAGAAACGAGAGCTCGAGTGCGGGCCGCGCGGGATTACGGGAATCGCACAGACAGGCCTGTGAACACGTGCGAAAATGCTCGTGCCTCGACGTTTGCACCCTTGGCATCGATCGTCCTCTCGCTTAGCGTGCTTTCCGTCGTCGGAGAAAAATCCGATCTCTTCATTCCTCTCCACATCCCTCCGattaaaataaagaccGAGATTCTGGATGAGATTGAGAATTTTTCTGCCAACGATGAACTGGATATCGAACAGCATGTCAGAAATGTACCATTGGAAAATGTATCGCTCCATGAAGATTCCGAACAGATCCCAGAATCGGACTGTCAAAGAAATGCAAGCGTTTCACTTTCCCAGAGACAAATGGACGAGTACACTGATTTAAAGGAATACATCGTGGCACTGACAGGAGGAAGGCTTTTAATGTGCAGCGTCTGCAGGATCGAATTTCCGAACGAGATCGAATTCAGGACTCACATGATTGGACATAGCCATGAGAAACTTTTCCAGTGCGGATACTGCAGGAAACAATTCTTACGATCGTCAACCTTAAAGGATCACCTGCATATGCATTTTATTCCAAAGTCTTTCGCGTGCAGACAATGTGAACTCCAATTTCAGAGGAAACGTGCGTTGAAAAAACACCAGGCCGAAGCGCACTCAGGAGGAAGAACGTTCGAGTGTTCTATTTGCAAGAAAAAACTGCTGCACCACCGATCGCTGCGCGATCACAAGCTGACGCACGCTAACGCGAGGCTCCACGAATGTACGACTTGCGGCAAGGGCTTCCCGAGGTCCAGCAGCCTCCGGACTCACATGATCGTCCATACCGCGGACTCGCCGTTCGCGTGCGATCTCTGCCCGGCAAGGTTCAAGAGATCGTCGGTGCTGAAGACGCACAAGCTGACGCACACGGGCGTGAGAAGATTCGAGTGCGACATCTGCAAGCATCGTTTCCATCTGAAAGGGGCGCTCAAGCACCACATATTGGCGCATTACGGTATCAGGCCCTACAAATGCGAAGATTGCGGCAAGAGCTACAGAAGATCCTGGGGTCTCAAGGTACACAGATATCGACATACCGGTATAAAGCAATTCGAATGCGACTTTTGCAAGCTGCGTTTCAGCGTGAAGACAAAACTCGCGAATCACATTTATACGCATACCGGCGAGAAACCGTACAAATGTGACATTTGCAGCCGTCAGTACTGCGAGAGATATCAGTTGAAAGCGCACAGGAGTACACGACATTATTCGGTAACTCGTTGA
Protein Sequence
MVLNGETRARVRAARDYGNRTDRPVNTCENARASTFAPLASIVLSLSVLSVVGEKSDLFIPLHIPPIKIKTEILDEIENFSANDELDIEQHVRNVPLENVSLHEDSEQIPESDCQRNASVSLSQRQMDEYTDLKEYIVALTGGRLLMCSVCRIEFPNEIEFRTHMIGHSHEKLFQCGYCRKQFLRSSTLKDHLHMHFIPKSFACRQCELQFQRKRALKKHQAEAHSGGRTFECSICKKKLLHHRSLRDHKLTHANARLHECTTCGKGFPRSSSLRTHMIVHTADSPFACDLCPARFKRSSVLKTHKLTHTGVRRFECDICKHRFHLKGALKHHILAHYGIRPYKCEDCGKSYRRSWGLKVHRYRHTGIKQFECDFCKLRFSVKTKLANHIYTHTGEKPYKCDICSRQYCERYQLKAHRSTRHYSVTR