Basic Information

Insect: Ferdinandea cuprea
Gene Symbol: ZEB2
Assembly: GCA_963576555.1
Location: OY754959.1:113031673-113033957[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1.3e-05 0.002 19.3 2.7 2 23 212 234 211 234 0.96

2 12 0.00055 0.083 14.2 0.3 1 22 330 351 330 351 0.95

3 12 0.0013 0.19 13.1 0.6 2 20 416 434 415 436 0.92

4 12 3.4e-07 5.1e-05 24.3 1.0 1 23 444 466 444 466 0.98

5 12 0.00019 0.028 15.7 0.4 2 23 471 493 470 493 0.89

6 12 9.5e-07 0.00014 22.9 0.5 3 23 499 519 498 519 0.99

7 12 4e-08 6.1e-06 27.2 0.2 1 23 525 547 525 547 0.95

8 12 2e-06 0.0003 21.9 1.2 1 23 553 575 553 575 0.99

9 12 2.8e-06 0.00042 21.5 1.0 1 23 581 603 581 603 0.98

10 12 0.00076 0.12 13.8 0.7 3 23 611 631 609 631 0.98

11 12 0.0067 1 10.8 4.5 1 23 637 659 637 659 0.99

12 12 2.8e-06 0.00042 21.4 0.4 1 23 665 687 665 687 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1.3e-05	0.002	19.3	2.7	2	23	212	234	211	234	0.96
2	12	0.00055	0.083	14.2	0.3	1	22	330	351	330	351	0.95
3	12	0.0013	0.19	13.1	0.6	2	20	416	434	415	436	0.92
4	12	3.4e-07	5.1e-05	24.3	1.0	1	23	444	466	444	466	0.98
5	12	0.00019	0.028	15.7	0.4	2	23	471	493	470	493	0.89
6	12	9.5e-07	0.00014	22.9	0.5	3	23	499	519	498	519	0.99
7	12	4e-08	6.1e-06	27.2	0.2	1	23	525	547	525	547	0.95
8	12	2e-06	0.0003	21.9	1.2	1	23	553	575	553	575	0.99
9	12	2.8e-06	0.00042	21.5	1.0	1	23	581	603	581	603	0.98
10	12	0.00076	0.12	13.8	0.7	3	23	611	631	609	631	0.98
11	12	0.0067	1	10.8	4.5	1	23	637	659	637	659	0.99
12	12	2.8e-06	0.00042	21.4	0.4	1	23	665	687	665	687	0.99

Sequence Information

Coding Sequence: ATGTCACTAGAAATCGTGAAAATCTGCCGTACATGCCTAGCGCTGGACGGTGGTCTTTTATCCATCTATGACAACAAGGGCTCCACTGGTGGGGATTGTGTTGCAGATATGCTTGGAGATTTAACAACCAATACACCCAAAAGGTCTGATGGCATGCCCGAGAAGGTATGCCTATCATGCATCAGTGAAATAAATCGATGCTACTCTTTCAAAATGAAGTGCGAGAATTCGGATAGAACCCTGCGGCAGTTGCTCAACATAAGCAGCGAGGAGAAAGTCGTCGAGCAGCCGCTTGTGGAAAAGCCAATTATAATAGCAAACACTCCGATCAAAGCGGCTGACGAACAAAAGAAGCCACAGAAGCGAAAAGCCGACCCCTGCGTGAAAATCATACTAGAAGATCGAGTGGACGAATCGCCTGAAATATACTCGGTTCACGCGGAAGAGGAACTGGAAGCATCGTACTTTGTTATTGACTCCAatgatgaggaggaggaggaggacgaGAACGAAAATGAAAACACTGCCGAGGTGCAGAAACACGAATCCGAAGATAGTGCAAATTCGGACAACTTTGATTATTTATTCGAGAAATACAACATACGACAGCAACGCAACAAAAAACCCGAACTGAAGTGCTCGCAGTGTCCCATGAACTTTGTTCATCCGCGAAATCTAACCAAGCACATGCAAAAGCGTCACAACATAACGAATGTGGATCCGCAACCGCTTACCGAAAAAATTGACGAGGAGCACGAGGAATTCCAGGTGGAGTTCCGGGAAATAGAAGAAGTCGCAATAAAAGTCGAGGAAACACTGAAGGCAGCAGAGCAATGCACcgtgaaaaacaatatcgctAATATGGATACACAAAGCCAAGATCAAGAGGAAGCGGAGCACGAGGAATACGAGCTGGAGTTCCAACAAATGGATGATACCGATGTCAAAGACGTCGATTTAAGGACGAAAAAAACACGTATGCACGATCACCGCTGTCCGAACTGTGGTTTGGGATTTGCCCAGGACAAGTCACTTAGCAACCACATTAAGCGCGGTAAATGTACAGGAAAACTCAACATCGCTAGCGAGGACAAAAAAACGTTGGTTAACAGCAAAGAGGTACATATGGTCGCTGAACGCGAAGAAGTAGAGCACAAGCAATTCCAATTGGAGTTCGAACAAATGGAAGAATCCTTCGTCAAGGAACCGCTGAACGAGGAGGAAGAAGTGCCCAAGCAGGAGCTTCGTTGTCCGAACTGCGGTGCGGGATTTGCACACCAAAAGTCGCTCACCATTCACTTCCATCGAGGCAAATGCACCAGCGAAGAGCACTCCTGCCCACAGTGCAATAAGGTGTTTATCTCCGAAGAGAACCTGCGCGAACATATCAAAACACACACTCAAAAGATCACCTGCAATGACTGCAATGAAACGTTCGTCAGCAAAGAGCTGTTCGCCAGGCACAGGGTAGAAAAGCACAAAATGCGGAATCTATGTCCAATATGCAAGAAAGTCTTTACCATGCTGTCCACTCTGAAGGACCACATGCGCATCCACAGCGGCGAGCGACCGTTTCTCTGTCCCATTTGCGGCAAGGGCTTCACACAGAACGCCAATTTGAAGCAGCACATTATGCGCCACAATAACACGAAGCCGTTCAAATGCAGCGAGTGCTCGAGGTCGTTCGTCAGCAAGGGCGAACTATTCTCCCATGTTCGCAGCCATACGGGTGACCATCCCTTCGTCTGCGACACCTGCCAAGCGGCTTTCACCACGTCAAGTTCGCTGTTGAAGCACAAGCGGACGCATACGGGTGAGCGGCCCTATGGTTGCGACCTTTGTCCGATGAGGTTTACTGCGCTAAACACTCTCAAGAACCACCGTAGGACGCACACTGGCGAGAAGCCATTCAAGTGCAAATTTTGCATGCGGGGATTCGCCCAAAAGAGCGACTGCACCATTCACATGCGGACACATACCGGCGAGCGACGGTACGTTTGTCAGATATGCGGGTCCGCCTTCCAACAATCGGGCACGCTGCGCACCCACATGAAGACTCACCGCGACGTCAAGCAGGATGCGAAGCCTGTAGTAGATTGGGAAATGTCCGACAAACAACAGCCCATCGAAGCAGATCAGACCAACGAAGAAGCTGCCGTGGAAGAAATTATGCACTTTGCAATCGAGGAGTGTTCCAGTGAGAACAACGACTTCCCAGGCGAATAG
Protein Sequence: MSLEIVKICRTCLALDGGLLSIYDNKGSTGGDCVADMLGDLTTNTPKRSDGMPEKVCLSCISEINRCYSFKMKCENSDRTLRQLLNISSEEKVVEQPLVEKPIIIANTPIKAADEQKKPQKRKADPCVKIILEDRVDESPEIYSVHAEEELEASYFVIDSNDEEEEEDENENENTAEVQKHESEDSANSDNFDYLFEKYNIRQQRNKKPELKCSQCPMNFVHPRNLTKHMQKRHNITNVDPQPLTEKIDEEHEEFQVEFREIEEVAIKVEETLKAAEQCTVKNNIANMDTQSQDQEEAEHEEYELEFQQMDDTDVKDVDLRTKKTRMHDHRCPNCGLGFAQDKSLSNHIKRGKCTGKLNIASEDKKTLVNSKEVHMVAEREEVEHKQFQLEFEQMEESFVKEPLNEEEEVPKQELRCPNCGAGFAHQKSLTIHFHRGKCTSEEHSCPQCNKVFISEENLREHIKTHTQKITCNDCNETFVSKELFARHRVEKHKMRNLCPICKKVFTMLSTLKDHMRIHSGERPFLCPICGKGFTQNANLKQHIMRHNNTKPFKCSECSRSFVSKGELFSHVRSHTGDHPFVCDTCQAAFTTSSSLLKHKRTHTGERPYGCDLCPMRFTALNTLKNHRRTHTGEKPFKCKFCMRGFAQKSDCTIHMRTHTGERRYVCQICGSAFQQSGTLRTHMKTHRDVKQDAKPVVDWEMSDKQQPIEADQTNEEAAVEEIMHFAIEECSSENNDFPGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -