Basic Information

Gene Symbol
-
Assembly
GCA_951449985.1
Location
OX602112.1:10015448-10022658[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 28 0.0002 0.014 16.2 3.3 1 23 197 219 197 219 0.99
2 28 0.0019 0.14 13.1 0.2 3 20 252 269 250 271 0.93
3 28 9.5e-06 0.00067 20.3 1.0 3 23 302 323 300 323 0.96
4 28 1.9e-05 0.0014 19.4 0.1 1 23 374 397 374 397 0.97
5 28 0.093 6.6 7.8 0.1 1 23 412 434 412 434 0.95
6 28 0.0028 0.2 12.6 0.8 2 23 474 496 473 496 0.95
7 28 0.0011 0.076 13.9 4.2 2 23 537 559 537 559 0.97
8 28 0.00099 0.07 14.0 0.6 1 23 609 632 609 632 0.97
9 28 0.0039 0.27 12.1 0.2 1 23 688 710 688 710 0.97
10 28 0.0023 0.16 12.8 5.1 2 23 722 743 721 743 0.97
11 28 0.058 4.1 8.4 1.3 2 23 755 776 754 776 0.96
12 28 0.0031 0.22 12.4 2.2 1 23 786 808 786 808 0.98
13 28 0.058 4.1 8.4 6.8 1 23 837 859 837 859 0.95
14 28 0.00043 0.03 15.1 2.5 1 23 870 892 870 892 0.98
15 28 1.4e-05 0.00098 19.8 0.9 1 23 900 922 900 922 0.97
16 28 0.00028 0.02 15.7 0.2 2 23 942 964 941 964 0.97
17 28 0.34 24 6.0 0.2 1 23 982 1004 982 1004 0.92
18 28 0.078 5.5 8.0 4.1 1 23 1011 1033 1011 1033 0.98
19 28 0.0065 0.46 11.4 1.9 2 23 1044 1066 1043 1066 0.95
20 28 0.0011 0.074 13.9 0.2 2 23 1089 1110 1088 1110 0.95
21 28 0.00071 0.05 14.4 0.2 2 23 1191 1212 1190 1212 0.95
22 28 0.11 7.6 7.6 5.0 3 23 1220 1240 1218 1240 0.96
23 28 0.014 0.97 10.4 0.8 2 23 1251 1273 1250 1273 0.95
24 28 0.6 42 5.2 3.3 2 23 1290 1308 1290 1308 0.88
25 28 2.1 1.5e+02 3.5 2.1 2 20 1312 1330 1311 1332 0.92
26 28 0.17 12 6.9 0.5 2 23 1380 1401 1379 1401 0.93
27 28 0.0037 0.26 12.2 0.4 2 23 1412 1434 1411 1434 0.95
28 28 2.4 1.7e+02 3.3 3.5 2 20 1472 1490 1471 1492 0.92

Sequence Information

Coding Sequence
ATGGCCCTCAAACTTGGAAAATGTAGGCTTTGCCTAAAACTGGGCGACTTTTACTCGATATTCACTGCCGATAATGGATTGCAACTATCTGAGATGGTTATGGAATGTGCAAGGATTAaagtatACGAAGGAGATGGACTACCAGACAAAGTATGTTCGGAATGCATTCAAAAGCTTAGCAGCGCTTATATTTTCAAACAGCAGTGCGAAAGATCTGATCAGGAATTACGACGGAACTACGTTCCGCCTCCAGGTTTCAGTATCAGCCCCCCACCACCCACCAGGCAGAGCAGTGATTCGGCGTTTTCAACTCACACAGACATTTCCAAACCATCATCTTCCACCGAAGGCAAAGGCACCCCAGCTGCGAGAAATCGCAAGAGAAGCCTCGAAAGCATTGACAATGGCTCAGTCGGCAGCCGCTCGCAGGAATATAGGTCGTCTAGTTCAAAACGCGTCGAGGAACTGAGGAAAACTCACAAAAAGCTGAGAACGGATTCTGAAAATATATCGTCAGATTACGACGACAATAGCGCATCCAATTTCATGGGCGAGACCGATTCAGATGAACCACTCATGAGCAGCGAATACAAGTGTAAGAGTTGCCCCAAAATCTTCAAGAGCTATAGGAGTCTCTCCAACCACTCGCGGACCCACAGCGCGAGTAAGAAAGCCAATACGAGCCAGGACACAGTGGTGGACATTCCTAACATAAGCACCGAGGACGCGGCCGACGTTGAAGACAAGCTGGCTTGCGACAAGTGCGACAAGACATTCAAACTAAAGATCATGTTGAATCGGCACAAAGACGTGTGTGGGAAAGAACACCTCAAACCACAGATTCAGAAGGAGCTTTTAATATCGCTCGAGCCCATAGACCGAAAGCAGATCAATAAGATCGACTGCCAAATGTGTACAACGAAGTTTAAGACAAAAGAGAACCTCGAGAAACACATGAAGGTGGTGCACGCGGCGGTGCTGAAAAAAACCTACTCGCAACCTAGCTTGGAGAATGGCGCAGTGTCTGTGCCTTGTATTTACTGCAAGGAGAATTTCGACGACTTCTATCTGCACTCGGCCCATTTCAGCGCATGCTCGAAGCGGGACGATTCGATACCGTACAAATGTCCGACCTGTGGCAAGGTGTTGAGTAGGAAGGCGGCGTACATCGCGCACCTGAAGAACATCCACTTCGAGCCGCGCTGCAAGCCGCAGGAGGAACAGCTGGAGTACTACCAGTGCCGCATGTGTAACAAGAAGCTGGCCACCCAGGAAATACTGATCACGCACCTCGCCGCGCACATGTCCAACATTGAGGAGGGAGAGGACGTCGACGACAACACCGGAGCGAGCATGCATGACGAAACTGGGTCTATTCATTCAACGTACAGTGGCAAGTATGTATCGAATGGTCCTCTCAAATGTACACTTTGCGCCAAAAAATTCACGTACAAGAAAGCGCTGCTGACCCACGTGGAGAGAGTCCATTCCGATCAGACTGAAGTGGAAGTTAAGGAGGAATTGTTAGAAAATACTTCAACAAGCCTCCTGAGCGAAACTTACCGCCAGTCTGAGTCTGAATCTAGTCAAGAAGAAGGAGACGACAACACGTGTGATATTTGCGAGAAACAGTTCTCTTACAAACGCTTACTTCTACACCACAAGCGGACAAAACACAACATGAGCTCTGGCACGAAGAGAGCCAAAATCAATCTGAAAGACTGCTCTGTGAAATGTCTGATATGTGATGTGGAGATGAAAGTGAGCGCCATTAATGAGCACAACCAGAAACATATATCGGTGAACATGAAGCCTCGCAATGTGTACACGTGTGCGGAGTGCGGGGACAAGTTCAAGAGCTGCAGTGGGCTCGCGAACCACATCAAGTTGGTCCACAGACTGAAACAGCAGCTCCCCAAGATACAGGGAGAGATGGCGGATTTTTGTGAGGTCGTTGTGACGAAAGCGGAACCCCTGGACTCCGAACCCTGGAGCCAGAGTCGCAACGACTTCCTGGAGGTTCCGCTCAGTGATAGCAAGGCGCTCGTGAACCTGAGTGGGTTCACTTGCCCCATCTGCAGCAAGAAGATGCCGACACTTATATCGCTCAAGAGGCACGTCAACTGGCATTCCAATGTCGGCAATAACATACAGAAGATTATCGAGTGTTTTGTCTGCAAAGAGACATTCAGATTCCAGTGCCACTACAAGATCCATATGCGCGTCCACTACCACGACACCAACCTAGACCCTAAATTCCTCACGTGTACGATCTGCGATCGCCGCAGCAAGCATCTCCGCGCCGCCATGGCGCACATGAACTTCCACAAACAAACCCGGTTCAAGAATAAAGACTACCAATGCTCCATTTGCAAGAGGGTGTTCCAACACAGAAAAGTTTACCTTTCACATATGGCCATACATTACAAACGCGGTGAGAGTATCCAGAACACAATCGTGGGCGACGCCCTGCCCAACTCTGCAGATAAAACTGTATTCGACGGCACGCATACATGTCACCTTTGCGGGAAGATATGTGACTCGGAAACGTCTTTAAAGCATCATGTCACGTGGCACAAGTCAAAAACGTCACTGTTCGGCGCCCGCCACGAATGCTACATTTGCCAGCTCGTGTTCACAAACAAGAGGAGACTCGAGATACACACGCGAACGCACTTTGAGGACGAAAACGGCCCTTTCAAGTGTACCATTTGCGGGAAAGGGTTCACCGAAGAGGATTATTTCAAGCGACACGTTAAGGGACATAACTTCGACCATCAGTCCCATAAAAAACGTATAGAGAAACTTAGAAAGGATAAAGTGAAGTGTCCTATTTGTACTCGGTTCTACCCAGATTTGGTGAAGCTCATCAGGCATCTGAGGAGGATGCATCCGGAAAGCAAGATGATCAAGCAAGACCCCGACGCGCCTCCCCCGCTCTACTACTCGTGCAAACTCTGCGCCAAAGTTTTCCTCGACCCACGCAGGCTGCAGAGCCACGAGGAAGCGCATTTAAGGAAACCAGAGTTTTTCAAGTGCAAATTCTGCGGAAAAAACACAATATCCCTAAAAAATCATAGGGTTCATATAAAATCTCATTTGACACAGAAGTATATAGACAATCCCCTGAAGTGCTCCGAATGCGAAGAGACATTTGTAAAGGGATACGACCTGCACCACCACTTGCGCGACGTTCATAACATCAATGAGACCTGGATGGCTGAGCGGAAAGAGCTCACGCTAGATGGACCTTTGAAGGATTTACAATGCTCTATCTGTTACAAAGTATTAGCCAGTAAAGGAAACTACGAGAGGCACATAGACTACCACAATTCTCTCCGGTGCAACTATTGTTTTGATTACTTCAGCACAATGAGGTTCCTCGAAGGCCATCTGGCGTTTAGCTGCCATAAGAGGAAGCTAATTGGCGACACTGAAGTGCATCCCAGGAAAGTGAAGTGTCATTGGTGTTACAAAGCATTCCACTTGCAAGTGAAGCTGGACTGTCACTTGCGAACACAACACGACGTGAGGGTGTGTAAGGAGGCCTCGGAGAACAAGCAGGAGATTGTCTGTGATTACTGCTTCAAAGTGTTCGAAAACGAATACGCATTgaacaatcataaaatataccaCCGCACTATTGGCTACTTTGGCTGTCTCTACTGCAATAGGAAGTTTAACACGTTAACGCTGTACAggaaacataaaaatcatcaCTTCTCTCAGCTCAATGTGGATAATCCCACTAAATGTGAGCACTGTGATGAGACGTTTGTTGCGTTCAGAGAGATGATATATCATATGCGGGATGTTCACAATGATGAGAAGGAGTGGGTTGTGATGCCCAAAGAGTCGATCGAAGAAACTTGTCCCATTTGTAAAAAGGTTTTCTTCAATTTACATAAGCATCTCACTTATCATGAAGAAAACAAGTGCAAGAAATGTAATGAATACTTCTACTCTAGATTAGACTACGACAACCATCTGTGCGGCATCGATAGTGACGAGGAATTGACGGAAACTAACGAAAATGTACCCGCCAAGTACCAAGAATGCACCTTCTGTTTCAAGCCAATCACTAAGAAAGATTCAAAGTTGAAACATGATAAAATTCACAGGGGATCTGGCTCCATATCTTGTAGGTTCTGCCCACTCAAGTTTAagactatggacgctttcaaCATTCATGCATTCTCCCACCGTAGTAGAAAGTATAATAAGAAACCTATCAAATGTCGGAAATGCGGCGAGAAATTCGTCAAATATGGACCTTTTATGAAACACATGAAGGCTGCTCATAAGTCGATAAAGAAGGTGCATTACAGGACGACGGTAAAGCCCGAGCGGTGCGCGGTCTGCGGCGACAGCTTCCCCAATCTCCACAACCACTACAGAGCACatttgctgaaccaatgtcAACTCTGTCGCAAGTACTTCACATCTTCCAAGGTGTTCTCAAAACACGAATGCAATAAAGAAGATTTGGATCCCTCTAAAGTATTCACCTGTGATGAAAATCTCCAGAGTCTTATAAAATCGTATGTTCCGAAAGATGAGAAAGATGATGAAAAGTTCTACGGGCACACTGATGATGAAGAAGACGAAAATGAAACATTCCCCGAACCCACAGATGAAGTGACTCAACATGAAAGAAAAGTGCATTCATTCGCCCAATCACCTATTATATCTGATGTATTGTCACTTTATCAAAAACATGATATTGATAGTCAAAATGGTAGTCAAGTCGATGCCGCCAGCCAGAACGGTGACGAGCTTAGTCAAAACGGTGATGATgatgtaaattgtaatgatGATGCGGTAAGTGTGGTGAATTTGGCTGATGACGATTCTGTGGACGTGCATGATGCGGCTGAAGCTGTTATTGTTGTGATAGATGACGATTGA
Protein Sequence
MALKLGKCRLCLKLGDFYSIFTADNGLQLSEMVMECARIKVYEGDGLPDKVCSECIQKLSSAYIFKQQCERSDQELRRNYVPPPGFSISPPPPTRQSSDSAFSTHTDISKPSSSTEGKGTPAARNRKRSLESIDNGSVGSRSQEYRSSSSKRVEELRKTHKKLRTDSENISSDYDDNSASNFMGETDSDEPLMSSEYKCKSCPKIFKSYRSLSNHSRTHSASKKANTSQDTVVDIPNISTEDAADVEDKLACDKCDKTFKLKIMLNRHKDVCGKEHLKPQIQKELLISLEPIDRKQINKIDCQMCTTKFKTKENLEKHMKVVHAAVLKKTYSQPSLENGAVSVPCIYCKENFDDFYLHSAHFSACSKRDDSIPYKCPTCGKVLSRKAAYIAHLKNIHFEPRCKPQEEQLEYYQCRMCNKKLATQEILITHLAAHMSNIEEGEDVDDNTGASMHDETGSIHSTYSGKYVSNGPLKCTLCAKKFTYKKALLTHVERVHSDQTEVEVKEELLENTSTSLLSETYRQSESESSQEEGDDNTCDICEKQFSYKRLLLHHKRTKHNMSSGTKRAKINLKDCSVKCLICDVEMKVSAINEHNQKHISVNMKPRNVYTCAECGDKFKSCSGLANHIKLVHRLKQQLPKIQGEMADFCEVVVTKAEPLDSEPWSQSRNDFLEVPLSDSKALVNLSGFTCPICSKKMPTLISLKRHVNWHSNVGNNIQKIIECFVCKETFRFQCHYKIHMRVHYHDTNLDPKFLTCTICDRRSKHLRAAMAHMNFHKQTRFKNKDYQCSICKRVFQHRKVYLSHMAIHYKRGESIQNTIVGDALPNSADKTVFDGTHTCHLCGKICDSETSLKHHVTWHKSKTSLFGARHECYICQLVFTNKRRLEIHTRTHFEDENGPFKCTICGKGFTEEDYFKRHVKGHNFDHQSHKKRIEKLRKDKVKCPICTRFYPDLVKLIRHLRRMHPESKMIKQDPDAPPPLYYSCKLCAKVFLDPRRLQSHEEAHLRKPEFFKCKFCGKNTISLKNHRVHIKSHLTQKYIDNPLKCSECEETFVKGYDLHHHLRDVHNINETWMAERKELTLDGPLKDLQCSICYKVLASKGNYERHIDYHNSLRCNYCFDYFSTMRFLEGHLAFSCHKRKLIGDTEVHPRKVKCHWCYKAFHLQVKLDCHLRTQHDVRVCKEASENKQEIVCDYCFKVFENEYALNNHKIYHRTIGYFGCLYCNRKFNTLTLYRKHKNHHFSQLNVDNPTKCEHCDETFVAFREMIYHMRDVHNDEKEWVVMPKESIEETCPICKKVFFNLHKHLTYHEENKCKKCNEYFYSRLDYDNHLCGIDSDEELTETNENVPAKYQECTFCFKPITKKDSKLKHDKIHRGSGSISCRFCPLKFKTMDAFNIHAFSHRSRKYNKKPIKCRKCGEKFVKYGPFMKHMKAAHKSIKKVHYRTTVKPERCAVCGDSFPNLHNHYRAHLLNQCQLCRKYFTSSKVFSKHECNKEDLDPSKVFTCDENLQSLIKSYVPKDEKDDEKFYGHTDDEEDENETFPEPTDEVTQHERKVHSFAQSPIISDVLSLYQKHDIDSQNGSQVDAASQNGDELSQNGDDDVNCNDDAVSVVNLADDDSVDVHDAAEAVIVVIDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-