Basic Information

Gene Symbol
-
Assembly
GCA_951449985.1
Location
OX602138.1:1824946-1829439[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 30 0.00031 0.022 15.6 1.0 1 23 47 69 47 69 0.98
2 30 0.5 35 5.5 0.0 2 23 97 119 96 119 0.91
3 30 0.0017 0.12 13.2 1.0 2 23 140 162 139 162 0.95
4 30 0.00046 0.032 15.0 2.3 3 23 169 189 167 190 0.95
5 30 0.014 0.98 10.4 0.7 1 23 194 217 194 217 0.95
6 30 0.0038 0.27 12.1 2.0 2 23 220 242 219 242 0.97
7 30 0.45 32 5.6 0.8 2 19 248 265 248 267 0.93
8 30 0.0039 0.27 12.1 2.1 1 22 318 339 318 341 0.90
9 30 3.4 2.4e+02 2.8 0.0 2 22 370 390 369 392 0.87
10 30 0.49 35 5.5 0.3 1 23 414 437 414 437 0.93
11 30 1.4e-06 0.0001 22.9 0.9 1 23 442 465 442 465 0.95
12 30 0.00043 0.03 15.1 0.4 1 23 470 493 470 493 0.95
13 30 0.0011 0.075 13.9 1.1 2 23 499 521 498 521 0.96
14 30 0.00033 0.023 15.5 4.7 1 23 525 548 525 548 0.98
15 30 0.39 27 5.8 0.8 2 23 555 576 554 576 0.96
16 30 0.029 2 9.4 1.6 1 23 615 637 615 637 0.93
17 30 0.45 32 5.6 0.0 2 23 665 687 664 687 0.87
18 30 0.053 3.7 8.5 1.6 2 23 708 730 708 730 0.95
19 30 1 72 4.5 2.6 1 23 735 758 735 758 0.92
20 30 0.00051 0.036 14.9 0.6 1 23 763 786 763 786 0.97
21 30 0.0046 0.32 11.9 0.6 2 23 789 811 789 811 0.94
22 30 0.13 9.3 7.3 0.6 2 21 818 837 817 838 0.93
23 30 0.02 1.4 9.9 4.0 1 23 897 920 897 920 0.94
24 30 0.00047 0.033 15.0 0.2 2 23 993 1015 992 1015 0.96
25 30 2.3e-05 0.0016 19.1 0.6 3 23 1022 1043 1021 1043 0.93
26 30 0.001 0.073 13.9 3.3 2 23 1048 1070 1047 1070 0.94
27 30 0.0067 0.47 11.4 3.7 1 23 1075 1098 1075 1098 0.97
28 30 6.5e-06 0.00046 20.8 5.0 1 23 1102 1125 1102 1125 0.97
29 30 0.00089 0.063 14.1 1.1 2 23 1132 1153 1131 1153 0.96
30 30 5.6e-06 0.0004 21.0 0.6 1 23 1159 1181 1159 1181 0.98

Sequence Information

Coding Sequence
ATGGTCATTCTCCGTTACAAAGTAGAATATTTCTTTTCAGATGACGCGCCAAGACAGAGTGCAAATTACGCAAGACGACGCAATCTCCAAATTCTATTTAACAATACCACCTTGTTTCCTTTCAAATGGCGTGGAAAGTACATGTGCTTCTACTGTGGAGAAGATTTTGACGGTTATAAAAGTCTGGAAAAGCACACACGAAGCCACGGCCTTTGTTCAGGCAATGATCGAGCCATAAAATTGGTTAAAGCTTTCGATAGCGAAGTAAAAATTGACGTTTCCGACATAACTTGCACGATCTGTGATGAAACGCTGCCTAGTTTAGCAGATATCGTCTCTCATTTGATACTTAAACACGGCCTTCCGTACGATAAAGAAGTAGAACTCATGATTACGGCCTACAGACTTGTAGACCTTAAATGTTTGGTTTGCGATCAAAGTTTCCGATATTTCCGTTACTTGGTGAAACACGTGAACAGTAGTCACCCGGACAATTGCCTGCTGTGCCAGAAATGCGATCAGATTTTCAACAAAAAGAGAGACCTAGATTCCCATATGAGGATTCATCATAAGCAGGAGTATAATTGCATGAAATGCGCACAGAAATTCATGAACAATGCGTCTCTACAGAATCACAGATTGAACGCTCACGTATCCACGTGTAACATCTGCTTCCAAACTTTCCCTTCGAATAACAAAAGGCTGAAGCATATGAAAACAGATCACGTAGCGGATGTAGCGGAATGTGGGTTCTGTTTTAAAACGTTGACTACGAAACAGGCTTTCTTCAGACACGCTACGCAATGTAACGCGCAGAAAAATGAACAAGAAAGCAATACGATAATCATAGATGATGAAGATAAAAGGCAAACTGTTAAAATTATGAGAAATAATATAGCTTGTGTCCTAAACATGTCAACAGCTATACCTTTcaaattctttttaaatagattCCGATGTTTCTACTGCTCAAAAGACTTTATCGACTGCGATGATCTCAAAGAACACACCGGTTTAGAACATCCCTATTGCGATATTAAGTTTAAATCAATGAAATTACGGAACCGTTACGAtggtattaatattaaaatcgacACGTCTTCCCTGTCCTGTAAACTTTGCTTCGAAACTATACCAAACTTGGACCTGCTTGTAGACCATTTGGTAGCAGAGCACAAAGCCACTTACGACAAATCCGTCGAAAGCAACTTACAGCCCTTCAGCTTGGTCAAAGATAATTTCGTTTGTCCCTTATGTGGTGAAGGGCACAGATACTTTGGGATGCTTTTAAAACACGTCAGTGTTACACATACGTTCAACAATTTCATATGCACTTACTGTGGAAAGTCTTTTAGGACTAATCCGAGTTTGCGGGCTCATGTTTCGCGTCGCCATAAAGGTTTAAGACACAAATGTGATGTCTGCGATTTAGGATTCACCAGTAACGCAGTTCTGAAATCGCACATGGGTAGAGTTCATGGAAGCAATGTAGTGAAGTGTACGCAGTGCTCGGAGAAGTTTCCGACTAGGTACACAATGCAGAAGCATTTGCTTATCACACACGGTACCGGGTATAAATGCACGCATTGTTTGAAGCTCTTTACGAGAAACTCCAACATGGTGAACCACGTGAGGAGGTTTCATTTGAAGGAGAAGAATGTGAGGTGTACCCTGTGCTCGGAACTGTTCTTTGACACGCAAAGGCTTAAGATTCATATGGTGAAGCATATAGATGAATATCAACCAGGACCGTACGAAAGCTGTACCTCTGAGAGACGACGAAAGAATATGAAAATACTGTTCAACCACACGACTGTGATGCCGTTCAAATGGCGTGGCAGGTTTCTTTGCTTCTACTGTACTAAAAGCTACACTGAATACCCAGAGTTCAGGAAACACACGCTGGCCCACGGTCTTTGCACCACAAAGGATTACGCCCTGAAAGCTATCAAGGGAAATcacattgaaattaagattGACGTCTCAGAGATAGTCTGCGACATTTGCAATGAATCTTTTGATTGGTTCTCAGATATTATTGATCACTTGAACGTGGTGCATGGTTTGGGGTACGATAAAGATGTGGACATACCGTTCCAAGAATACAGACTGGCTGATGGTAAATGCTTATTGTGTGAAGAGAAGTTTACTTACTTTGGCCATTTGGTGACCCATGTCAACAATACGCATCCTCAAAACAGCTTTATTTGTGACGAGTGTGCATTGTCGTTTAATAAGAAACGGGATCTGGCCTGCCATTTCAGGAACTACCATCGCCAAGGTGGCTACCCATGCGATCAATGCGTACAGActtttgaaactaaaataaacttaagcACGCACAGGAATAAAGTGCATTTTAGAGAATGCAGTAACTGTGATATGAGATTTGGATCTCTGACACTCCTACAGAAACACACGCAGCTCGATCACCCCGAGGTATGCGAGTTGAAATGCAgttattgtttgaaaatctTTCACACTGCCCAAGGAGTAAAGCTGCACATGAGCAGGTGTAAAGTGAGGATGATAGCGCATGCGCATATGCCGGCAATAAACGCCCTCCCGGAAGACAGAATAATGGTACCGGTCGTGCCGAAAAAGAACCAGAACATCATACAAATAAGACTTAATATACAATGTGTGTTAAACATGTCGACTGCGGTGCCTTTTAAATTTTTCGCCAAGTTCAGCTGCTTCTACTGTTCAAAAAAGTTTATAGAATTTGACGAACTAAAACACCATACATCTCAAGAGCATCCTATCTGTGAGTTGAAGTCTAAAGCTTTGAGGACGTGCAAAGGGGAAAGAATATCCGTGAAAATTGACGTTTCGTCTTTGTCTTGTAAGCTGTGCTGCCTTCCCATGGCCGATTTAGACACACTAGTAGACCATATCATTGCGGAACACAAAGCTAATTACAACAAGGCTGTAAAGGGATGTCTAGAACCGTTTAGGATTTTGAAAGACAATATCCCGTGTCCCATATGTGAGGAACGTTTTAGGTATTTCACAACCTTattgaaacatttaaattCAGTCCACAACGACAATAATAGGATATGCGATTTTTGCGGACGTAGTTTTAGAAACGTGTCCAATCTTAAAGCCCATCTAACGTATTCGCATACAGGAGTTTGCGAGTGCAATATTTGCGGGTTGAAGTTCAAGAATCTAGCCTGTCTAGCTCGGCACAGGGCTAGGACTCACGATGCGAAAGATTTCAAATGCCCCAAATGTTCAGAGAGGTTCCAAAGCGAATATCACAAGCAGAAGCATTTGATTAGAGAACACGATATTGGACATAAGTGCTCTTATTGCGGCAAAATGTTCACGAGAAACTCGTTTATGAAAGATCACATTAGGAGAACGCATTTGAAAGAGAAAAATGTACCGTGTTCCGTCTGCAATGAGAAGTTTTTCGATAATCACTTGCTAAGGATGCATATGGTCAAACATGATGGGGAAAGAAAGTTTACCTGCACGGTTTGCGGTAAGGCCTTCTTGAGGAGAAGTAACCTGAGCTCGCATATGGAAATGCACAAGAAGTATGGCCAACTTCAGGTGCCCATTTag
Protein Sequence
MVILRYKVEYFFSDDAPRQSANYARRRNLQILFNNTTLFPFKWRGKYMCFYCGEDFDGYKSLEKHTRSHGLCSGNDRAIKLVKAFDSEVKIDVSDITCTICDETLPSLADIVSHLILKHGLPYDKEVELMITAYRLVDLKCLVCDQSFRYFRYLVKHVNSSHPDNCLLCQKCDQIFNKKRDLDSHMRIHHKQEYNCMKCAQKFMNNASLQNHRLNAHVSTCNICFQTFPSNNKRLKHMKTDHVADVAECGFCFKTLTTKQAFFRHATQCNAQKNEQESNTIIIDDEDKRQTVKIMRNNIACVLNMSTAIPFKFFLNRFRCFYCSKDFIDCDDLKEHTGLEHPYCDIKFKSMKLRNRYDGINIKIDTSSLSCKLCFETIPNLDLLVDHLVAEHKATYDKSVESNLQPFSLVKDNFVCPLCGEGHRYFGMLLKHVSVTHTFNNFICTYCGKSFRTNPSLRAHVSRRHKGLRHKCDVCDLGFTSNAVLKSHMGRVHGSNVVKCTQCSEKFPTRYTMQKHLLITHGTGYKCTHCLKLFTRNSNMVNHVRRFHLKEKNVRCTLCSELFFDTQRLKIHMVKHIDEYQPGPYESCTSERRRKNMKILFNHTTVMPFKWRGRFLCFYCTKSYTEYPEFRKHTLAHGLCTTKDYALKAIKGNHIEIKIDVSEIVCDICNESFDWFSDIIDHLNVVHGLGYDKDVDIPFQEYRLADGKCLLCEEKFTYFGHLVTHVNNTHPQNSFICDECALSFNKKRDLACHFRNYHRQGGYPCDQCVQTFETKINLSTHRNKVHFRECSNCDMRFGSLTLLQKHTQLDHPEVCELKCSYCLKIFHTAQGVKLHMSRCKVRMIAHAHMPAINALPEDRIMVPVVPKKNQNIIQIRLNIQCVLNMSTAVPFKFFAKFSCFYCSKKFIEFDELKHHTSQEHPICELKSKALRTCKGERISVKIDVSSLSCKLCCLPMADLDTLVDHIIAEHKANYNKAVKGCLEPFRILKDNIPCPICEERFRYFTTLLKHLNSVHNDNNRICDFCGRSFRNVSNLKAHLTYSHTGVCECNICGLKFKNLACLARHRARTHDAKDFKCPKCSERFQSEYHKQKHLIREHDIGHKCSYCGKMFTRNSFMKDHIRRTHLKEKNVPCSVCNEKFFDNHLLRMHMVKHDGERKFTCTVCGKAFLRRSNLSSHMEMHKKYGQLQVPI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-