Basic Information

Insect: Fabriciana adippe
Gene Symbol: MBD-R2
Assembly: GCA_905404265.1
Location: FR990003.1:1352203-1368153[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.017 1.6 9.9 0.6 1 23 325 347 325 347 0.98

2 10 0.00045 0.041 14.9 7.1 1 23 354 376 354 377 0.95

3 10 0.052 4.7 8.4 1.8 1 23 381 403 381 403 0.97

4 10 0.054 4.9 8.3 2.1 1 23 408 431 408 431 0.97

5 10 0.016 1.5 10.0 0.2 1 23 435 458 435 458 0.93

6 10 0.0089 0.81 10.8 0.5 3 21 472 490 471 495 0.93

7 10 0.0069 0.63 11.1 1.1 2 20 575 593 574 596 0.89

8 10 0.00048 0.044 14.8 0.2 1 23 602 624 602 624 0.97

9 10 6.1e-06 0.00056 20.8 2.4 1 23 630 652 630 652 0.97

10 10 3.9e-05 0.0036 18.2 4.1 1 23 658 681 658 681 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.017	1.6	9.9	0.6	1	23	325	347	325	347	0.98
2	10	0.00045	0.041	14.9	7.1	1	23	354	376	354	377	0.95
3	10	0.052	4.7	8.4	1.8	1	23	381	403	381	403	0.97
4	10	0.054	4.9	8.3	2.1	1	23	408	431	408	431	0.97
5	10	0.016	1.5	10.0	0.2	1	23	435	458	435	458	0.93
6	10	0.0089	0.81	10.8	0.5	3	21	472	490	471	495	0.93
7	10	0.0069	0.63	11.1	1.1	2	20	575	593	574	596	0.89
8	10	0.00048	0.044	14.8	0.2	1	23	602	624	602	624	0.97
9	10	6.1e-06	0.00056	20.8	2.4	1	23	630	652	630	652	0.97
10	10	3.9e-05	0.0036	18.2	4.1	1	23	658	681	658	681	0.95

Sequence Information

Coding Sequence: ATGCGCTGTTGTATTCCTTCGTGTAAAAATGATTCAAGACACGTATCTAAGTCTGAAGGAATTACTTTTCATGCATTTCCAACAGAACCAAAAATAAGAGCAATTTGGTTTAAAGCTGTTGGTAAAAATGATTGGCCGCCTCGAGACAGGAGGGTGGTGTGCTCTGAACATTTTCTCTGTGAAGATTTGTATGAAACTAAGAATGGATTAAGAAAAGTTAGGATTGGTGCAGTGCCCGTAGTACAGGTTTGCAGAATATGCCTTGGTACCAATAGAAAGCTGTTTTCACTCAAAACATATGGCTTGGAGCAAATGTATGAGTGTCTCACAGGGATGTCGCCATGCAACGACAATTTACCTCAATGCCTATGTTCAGAATGTGCTCAAAGATTGTCGAATTGTATAAAATTTCGAAATAAAAGCTTAAAAGCGCATTCTTTGATGTTAAATTTGCTTGAACAACAGAATATTATAACATTAGAAAATTTAAAATTAATCAATCGGAAAGGGAACCAGTTAACTTCAAGTTTAAACAAAAAACTCTTCACCCCAGACCATTTTGACATATACATAGATGAATGCACAGAAGGTCAAAATATGAGGGCAGATAAATTAGAAAACGATATAAATTTAGACGAAGTGAAGAGTGAGAAGAATGACGAAGAGGATATATTTGTGGAAACCAACGATGATCTAAAAACATCGGATACAGAATTCTTGCCAAAGGAATATTCAACGGATGACAGTCTGCCATTGGAATGTCAGAGGAAGAAGAAGAAGAAGACGAAGATAAGAGAAGAGAAGAAAGCGAAGAAGAAGAAGGTGGAAGTACCAAAAATTGACAGACGTCGCAAACCTTTTTTGAATGATGATTTAAATGAAACCCTCTTCACAATAACTGATTTGACATTTGAAGAACAAGTAGCCGAGATAGAGAAAAGACAGGAGTCGTCAAACTATAAAAATTCAATGTTTAAATGTACGGAGTGTTTTAAAGGATTTTTGGATGAAGATGCCTATAATGGGCATATGACAAGGCATACTAATCAATGCGGAGAGTTCGAGTGCGATATATGCAAAACTCATTTCAAACATCCTCACGCGTTAAGGAAGCATATAACGGCGCATCATACGCAAAGGTTTAGTTGTAACCAATGTCCGTACGTCACTACACATAGACAAACAGCAAGGTTACACGAGCGATGGCATAAAGGAACTAAATACAAATGCCCTCACTGTCAAGACGAGTTTGTTAAATTCACAACGTACATGGGCCATATACGTATAAAGCATCCATCCGACTTCGTCTGCGCCCTCTGTGGGTATACTTTTGTGAGTGAGAAAGGTATCGAATTGCACAAGAAGTTGAAACATCGCCTTGATGATGGTTTGATACCAGAAGACGGACCACTCTGTGAACTTTGCAACGTCAAATTCGTCTCTCAAGACGCGTACAGACGACATCTGCACGTGTCTGCGAGGCATAATAATAGTGACTCAGATTCTAAGGATTCGAATAGAGCCAGAAGAGGTAGGAGATCGAAGGAGATAAAAGATGTGGACAGCAAGAGAGACAGAAGTAGAGAAGGCAGTGAGAAGAGAAAAGTGTATCAGAGTCAATGCGGTCTACAATTGGAAGATTCCAGAGCGTATCACGGTCACTTCAGAAGAATGCACCCGGACAAGAATCGAACCAAGTACCCCTCCATGAAGTCGCCCTGTATGTGCGAAGTGTGCGGGCGAATGTTCCAGAGCTACGCCCTGCTGAAGGACCACCGCTGGACGCACACCGGCGAGCGGCCGTTCGCGTGCGAGGCGTGCGGCAAGGCCTTCCGCATGCGCCAGCGGCTCGTGGCGCACCGCCGCGTGCACGCCGCGCGCCGCCACTACGCCTGCGCGCTCTGCGGGAAGACCTTCTCCACGCACAGCAACCGCCAGCGGCACATGTTCATTCACACAGGTTTGAAGCCGTTCAAATGTGAAATGTGCGGGAAGTGTTTCAAGCACGCCAGCGAGAAGCGTGCTCATATAACTTACGTACACCTCAAGAAGCCGTGGCCCAAACGGGCGAGGGCTAAACGCAGAGAGAGACAGGGTCAAGCGCAAGAAATCGAAGAGGGTGGTAGTGAAGTCCACATGGCACCAGTTTGGCCTCAACAGGATCTCAAATCTACGTACTGTCATCTTAGAGTGTAA
Protein Sequence: MRCCIPSCKNDSRHVSKSEGITFHAFPTEPKIRAIWFKAVGKNDWPPRDRRVVCSEHFLCEDLYETKNGLRKVRIGAVPVVQVCRICLGTNRKLFSLKTYGLEQMYECLTGMSPCNDNLPQCLCSECAQRLSNCIKFRNKSLKAHSLMLNLLEQQNIITLENLKLINRKGNQLTSSLNKKLFTPDHFDIYIDECTEGQNMRADKLENDINLDEVKSEKNDEEDIFVETNDDLKTSDTEFLPKEYSTDDSLPLECQRKKKKKTKIREEKKAKKKKVEVPKIDRRRKPFLNDDLNETLFTITDLTFEEQVAEIEKRQESSNYKNSMFKCTECFKGFLDEDAYNGHMTRHTNQCGEFECDICKTHFKHPHALRKHITAHHTQRFSCNQCPYVTTHRQTARLHERWHKGTKYKCPHCQDEFVKFTTYMGHIRIKHPSDFVCALCGYTFVSEKGIELHKKLKHRLDDGLIPEDGPLCELCNVKFVSQDAYRRHLHVSARHNNSDSDSKDSNRARRGRRSKEIKDVDSKRDRSREGSEKRKVYQSQCGLQLEDSRAYHGHFRRMHPDKNRTKYPSMKSPCMCEVCGRMFQSYALLKDHRWTHTGERPFACEACGKAFRMRQRLVAHRRVHAARRHYACALCGKTFSTHSNRQRHMFIHTGLKPFKCEMCGKCFKHASEKRAHITYVHLKKPWPKRARAKRRERQGQAQEIEEGGSEVHMAPVWPQQDLKSTYCHLRV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00247268;
90% Identity: iTF_00723161; iTF_00247268; iTF_00248161; iTF_00248450; iTF_00247540;
80% Identity: iTF_00723161;