Basic Information

Gene Symbol
Sall1
Assembly
GCA_905404265.1
Location
FR989992.1:14926873-14943092[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 6.3 5.7e+02 1.8 0.2 2 23 6 27 5 27 0.93
2 13 0.017 1.6 9.9 0.3 1 23 1011 1034 1011 1034 0.92
3 13 8.7e-07 7.9e-05 23.4 2.0 2 23 1135 1156 1134 1156 0.97
4 13 0.00031 0.028 15.4 2.3 1 23 1162 1184 1162 1184 0.98
5 13 0.013 1.2 10.3 2.8 2 23 1191 1212 1190 1213 0.95
6 13 0.1 9.2 7.5 1.3 5 23 1226 1244 1224 1244 0.97
7 13 0.025 2.3 9.4 0.9 3 23 1251 1272 1250 1272 0.96
8 13 0.6 55 5.1 0.7 2 23 1287 1307 1286 1307 0.95
9 13 0.00014 0.013 16.5 0.8 1 20 1313 1332 1313 1335 0.91
10 13 0.0017 0.16 13.0 2.0 1 23 1343 1365 1343 1365 0.99
11 13 0.0047 0.43 11.7 7.2 1 23 1371 1393 1371 1393 0.98
12 13 6.5e-06 0.00059 20.7 1.4 1 23 1399 1423 1399 1423 0.98
13 13 0.00086 0.079 14.0 5.1 1 23 1429 1451 1429 1452 0.95

Sequence Information

Coding Sequence
ATGGATCAAAGAGTTCAGTGCCCTGTGTGTACACTGTACCTTCACAGTGGAATGTCATTAGCTTCACATTTGGATACACATCCAAAAGATCAAGTGATAAAAGCATTGTGTAGTCTGTCAGCAAAAAATATCAATTTTGGGAGCAGAAGTACTACTCCATTAAATTCAGAAAGGTCATATAGAAGCAGGTCACGAACCCCAGCAACAGATGACAGTGGTCGATGGGTTAGCTCACATCGTAATAGTGAAAATGACAGATATTGGAGGAGGACACCCAGTAGAAATAAATCAACCCCACTTTCAAGCACTTCAAGGAATCCTACTCCAGATATAAGAATTGGTAATATATCATTTGAGAACCATAACTCCAATAACAACTCCAGTCATTGTTCTGATTCATATACAGTAAAGTCTGATAAAACACAGAAGACATTTGGTTCTAATGGACAGTCTTCAGTTTCTGATTTTGCTCTGCAATATCCTTACTATCCAGAGCAACAAGATGATACAGAAATAAAGTTTTCGAGGAGCTCAGAGTACAGTGCACAAGTAGAGAATTCTAATCATTTATTTGGATATAATATGCCCATAATGGGGTCAGGAATAAAGCTTCCAACAGGCATGATGCCAACAGTGTCTAGAAGGGGTGGTGAATATGTCAAGATTCTACCTAAACAAGGAAACTTACTTGTAAAAACCAACATGAGTGGCATGCAATATGTGTCACCAGGAGCGAAACCATTGCATGTAATGATGCATACCCCACCACCATTTATTCAAAAAAATTTACAAAATAGTATGATCATGGCAGGAAGCATGCCAGGATCTCCTATGCTAGATCCAAAACACATGACACCATCAATGAATCCTCTTAGTAGTCAGGTTAATCCTCTAAGTGCTGGAGCATTCACTCCTGGAACTACAGTTGTTACACAAAACTCGCAAATAATCTATAGAGAGATGGTCCATAATATCGATGGTAAACCTTTTATGTCAAATATGCCACCTGTGCTTGGAGGTCCTGAAACTGTCACAAATGTGGCTCAAAGTAGTTCTATGTATCAAAATGTGATGGTTGTTGATCAATATGGTAATACTTCTTGCATGTACAGTACACCACAACATTTGTTACCAAAACCATGCAGTTCTATGTTTAATGAGAGTATTCCACCATATATGCAAAATATGCCTGAAAAAGCTGCACAAAATGTAGTCAATGATGCAAATAAAACCCTTATTATTGAAGTAAGTCCTATGTCATCAGATGCTTCAATAACTGCCAATGAAGAAAGTCAAAATTCACAGCCTTCACAACAGAGTATAAATCCTATAAAAAAAAAGCTTGAGAAAAAAAAGAGTGATCATAAAAATGGATCGCCAGGACCTAGTAAAGGTCTGAAAATTCTTAGTAATATAAAGGTAGAAGTTCCTGTACAACATCATAAGAATATGCTTAACACTGTTATGGACCTGACTGGTTCAACTGATTCTGATTATCCAGAGCCCTCAATTACTCCGGAGAAAATTTTACCAGATTTAGATGATGATAACCCAAGTATAATAATTGATGATTGCACTCAACGGTCAAGTGCTAGTGTAGATAGTCTAGCATCGAACACGTTTACAACTATAAAAAGTTCATCAAATCAATCATATAATAAGGATTCACCATCTAAATCCATTACTGTTGAAAATAAACTAGATACAGAATTCTCAGATAGCTGCCCAGTTCCTGATCTTATTTGCAATGAAAAACCGTCTATATCTCCTTGTAGTGAACTATCCGAACATGGCGATAATTCTACTGATCGCACCTTACCATCACCAAGACCTGAAAGTAGTCAACCATACCAAAGTTCGCTAAGTAATAATATTGAGATTGGTAAGAAATCTAGTAAAACACAAAGGAATAATGCTCTAAGGCTCAATAATATTTTTGTGAAAAAACACAAAAAAATTCTGCAAATAAAGAATTCCAAATTGGGTCCACCAGAAAGAATCGGTCAAACAGAGCTAGAGCCGAGACCATCATCGTCTTCATCTCGTAAATCCCCAGAAAATTTTTCAATAACAAAAATCCATCAGCCATCAGCCATAGCAGAACCGAAACACACATTACAAACTGTTAATATTGACAAAATCAAAGGCAATGATGTCGACGATCGTAACGAATTCGACGCTAATACAGAGGAACAGTCGATGGATATTGAACCAGTAACTCCGTCCAACGTGACCCATTCCAATCAATTTTCCAGCAACGGATATATTATGGTACACATTAAAGAAGAAATAAACTCAAGTAATGAGTTTAGTAATGAAGCTGTAAGATCCCCTGCGGATATTGCTCCAATGGAGACACTTAGACCCATTAATGTCATCAATTATAGTAATATGGCGGATTTTGATGACGATTCAAATCATAGGGAGCTATTAGAATTAGAGGCTGCTTCAAAAAATAAACAATTCGTGTCTATGATGAATGAAAATTACTTTGGTGACAATATTTATGCAGATTATTTCACTCCTGACCGAGGGGAGACTTTTGAAGCTCAAAAAGAATCAAATTATAGTAAAGACATCGCTAAAGATGGGGTGTACGTTTGGGGGGAACCGTCACAGAAAGAAAGCGAATTTGTTTTACCCAATTTTATTCATGAGAGTTACAAAATAGCGGAGAGTAATGGTATAGATTATTCCGATGTAGGAACAGGGAATGTGCAAACAAATGGAGATGGGGAGAGATGTGAAAGAGATAGTAAGGCAGATGTGTTGAGTGAGAGCAGGAGTGAGGGTGAGCCACCTCTAAACATATGTGCGGATGAACGAATGCCGCCCAGAGGAGAGCTGAGCGGGCAGGAGAGCAATGGAGATATGGAGTCACCTTGGAGCGGGATGTATTCTGGAGTGCCTCCCGCGGAACCTTACGATCTAATGGCGCGGGAAAGTTGGGTGTCAGATGGGTCCGAAGTCGATGAGAATGAAAAAACAGAAAATATAGAGGAGGATCATCATTTTCCCAAGGCTCGTATGTACCATTGTGCTCAATGTGGAGGGAAGTTCCCATCGCTTAAAGAATTACGTGCACATAAAGCATTAGTTCATGCATTACCAACTTGTTCCAATTCAAAAACATCTTACAGTCGCCTCATGACAGCACGGGCCATTAAGAAAGAGGAGAAGCCATATGAACATGTTTTAGCAGGAAATCTGTCACTGGACTCGAAAGAAACGATAGCGTCAGCCCTTCTTCAAGCATACAATCAATTTGAAGCGAAACCCCAAATTGAGGGTTTACTAAAGCGGCAAAATAAGAAGCGGCGTAAAGATTTCGTTTGTCCAACATGTAAGGTGGATCAAATGACGGGTGCAGCGTTCCACGCTCATCTCAAGATACATCCCCTCGAGTGTCTCACCTGTGGCAAATGTTTCACCCGACGAGCTAACCTCGCACTACATATGAAGACACATTTAGGGATAAAGAACTATAAGTGTGATATATGCGAGAAGCGGTTCATGACGCGGCAGAAGCTGGCGGAGCACCACAACATACACACGGGCCGCACGCCCGTCAAGTGCACGCTCTGCGACGACACCTTCCGCAGATACTCCAACATGGTGCAGCACAGGGACAGACACCATTTCAAGAAGAAAGCGAAGATCCGCGACTTCGTGTGCCACTGCGGGGCGGTGTTCCCGTCGCGCGCCAAGCTGCACTGGCACAAGGAGACGCACGAGGAGAAGCCCAAGGCGTGCCTCTACTGCAGCGACAAGTTCGTGCACGCGGCGCTGCTCACGCGCCACGTGCGCCGCTCGCACAACGAGCACTTCGTGAGCCAGCAGGGCAAGCTGGAGAACGTGCCGTGTCCTGTATGCAAACAGTTGTACCTACGATCGAAACTGCACGCCCATCTGCAAACGCACAGCGGCAAGCGGCCCTACAACTGCGTAATATGCAACAAGGGCTTCACCACTAAGTGGAACCTCAAACTTCACCGCTGGACGCACCTCAGCCGCTCCGCCAAGCCCTACAAATGCAACCTCTGTAAGGGCGCCTTCATACGACACACCGAGTACATCTCACACATGAACAGCCATAAGTCAGTCCGGCCCTACACATGCAACTACTGCGGCTGTCAGTTCATTAGAAAATACAACTGCCAACGTCACGTCCGCGAACACGAAATGGCCAAGAAGTATGTGTGTAAAGTGCCAGAGTGCGGTAAAACGTTTCATAGAAGTTATTATCTATCCGAACATATGAAAGTGCATAGTGGCGTGCGTCCGTTCTCCTGCAATATATGTGGGAAGACGTCCAGTAATAAATCAAATCATAACAAGCATGTGAAGATCCACCATGCTCGGGAACCTGTGACCACTGAAGCGTAA
Protein Sequence
MDQRVQCPVCTLYLHSGMSLASHLDTHPKDQVIKALCSLSAKNINFGSRSTTPLNSERSYRSRSRTPATDDSGRWVSSHRNSENDRYWRRTPSRNKSTPLSSTSRNPTPDIRIGNISFENHNSNNNSSHCSDSYTVKSDKTQKTFGSNGQSSVSDFALQYPYYPEQQDDTEIKFSRSSEYSAQVENSNHLFGYNMPIMGSGIKLPTGMMPTVSRRGGEYVKILPKQGNLLVKTNMSGMQYVSPGAKPLHVMMHTPPPFIQKNLQNSMIMAGSMPGSPMLDPKHMTPSMNPLSSQVNPLSAGAFTPGTTVVTQNSQIIYREMVHNIDGKPFMSNMPPVLGGPETVTNVAQSSSMYQNVMVVDQYGNTSCMYSTPQHLLPKPCSSMFNESIPPYMQNMPEKAAQNVVNDANKTLIIEVSPMSSDASITANEESQNSQPSQQSINPIKKKLEKKKSDHKNGSPGPSKGLKILSNIKVEVPVQHHKNMLNTVMDLTGSTDSDYPEPSITPEKILPDLDDDNPSIIIDDCTQRSSASVDSLASNTFTTIKSSSNQSYNKDSPSKSITVENKLDTEFSDSCPVPDLICNEKPSISPCSELSEHGDNSTDRTLPSPRPESSQPYQSSLSNNIEIGKKSSKTQRNNALRLNNIFVKKHKKILQIKNSKLGPPERIGQTELEPRPSSSSSRKSPENFSITKIHQPSAIAEPKHTLQTVNIDKIKGNDVDDRNEFDANTEEQSMDIEPVTPSNVTHSNQFSSNGYIMVHIKEEINSSNEFSNEAVRSPADIAPMETLRPINVINYSNMADFDDDSNHRELLELEAASKNKQFVSMMNENYFGDNIYADYFTPDRGETFEAQKESNYSKDIAKDGVYVWGEPSQKESEFVLPNFIHESYKIAESNGIDYSDVGTGNVQTNGDGERCERDSKADVLSESRSEGEPPLNICADERMPPRGELSGQESNGDMESPWSGMYSGVPPAEPYDLMARESWVSDGSEVDENEKTENIEEDHHFPKARMYHCAQCGGKFPSLKELRAHKALVHALPTCSNSKTSYSRLMTARAIKKEEKPYEHVLAGNLSLDSKETIASALLQAYNQFEAKPQIEGLLKRQNKKRRKDFVCPTCKVDQMTGAAFHAHLKIHPLECLTCGKCFTRRANLALHMKTHLGIKNYKCDICEKRFMTRQKLAEHHNIHTGRTPVKCTLCDDTFRRYSNMVQHRDRHHFKKKAKIRDFVCHCGAVFPSRAKLHWHKETHEEKPKACLYCSDKFVHAALLTRHVRRSHNEHFVSQQGKLENVPCPVCKQLYLRSKLHAHLQTHSGKRPYNCVICNKGFTTKWNLKLHRWTHLSRSAKPYKCNLCKGAFIRHTEYISHMNSHKSVRPYTCNYCGCQFIRKYNCQRHVREHEMAKKYVCKVPECGKTFHRSYYLSEHMKVHSGVRPFSCNICGKTSSNKSNHNKHVKIHHAREPVTTEA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00782936;
80% Identity
-