Eads001621.1
Basic Information
- Insect
- Exocentrus adspersus
- Gene Symbol
- lola
- Assembly
- GCA_029955175.1
- Location
- JANEYG010000002.1:4848985-4853499[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.047 3.2 9.1 0.2 2 21 65 84 64 85 0.93 2 13 0.22 15 7.0 1.0 1 17 93 109 93 110 0.94 3 13 0.0034 0.23 12.7 4.7 1 21 264 284 251 285 0.97 4 13 0.0089 0.61 11.4 0.9 3 23 295 318 294 318 0.89 5 13 9.4e-05 0.0064 17.6 0.6 1 21 326 346 326 347 0.96 6 13 0.86 58 5.1 0.7 1 23 355 380 355 380 0.93 7 13 0.00046 0.032 15.4 0.4 1 21 402 422 402 423 0.96 8 13 0.0075 0.51 11.6 3.9 1 23 431 456 431 456 0.94 9 13 7.9e-06 0.00054 21.0 1.7 2 23 498 520 498 520 0.93 10 13 0.00037 0.025 15.7 1.5 1 21 528 548 528 549 0.94 11 13 2.5e-06 0.00017 22.6 3.5 1 23 570 593 570 593 0.96 12 13 6.1e-06 0.00042 21.3 2.8 1 21 601 621 601 622 0.94 13 13 0.16 11 7.4 0.2 1 23 636 659 636 659 0.96
Sequence Information
- Coding Sequence
- ATGGACGAAGAACTCCCCGACGAAGTCCTGACGGATCTCGACCAGTTAAACCAATGGTACCACCTTCCGGCTGAGAATCCCGGCGGGAAAAGTGCCATGAAGAGGTGCAGGTGGTGCTCCAAGAAGAAAATACGGAAACGATCCAGGTACCATTGTCCTGGATGCGAGGGTCTGCCAGGTACCCAAAACTGGATCTGCCAAGTGTGCGGGAGGAGGTACTTGCACGAGAGATCTTTATGGAGGCACATCAAGTACGAGTGCCAGAAAGAACCTTCGTTCCAGTGCGGAGTTTGCAAGAGACTGTTCAAGTTGAAGTACCACTTGCAAAGCGAAACATTCTGTTGCAACGCTTGCGGTTTGCTGTTCACCTCCTGGCGTTCCTGCATCAAGCACAAGAAACAGTGCCTTCCCGTCGCAACACAAGCGTTGACCAATAAGGCGGCACGGAAGTACCGGAAAAGCACGAGTAAAGCCGACAAAGTCGTACCGCTTACGGAACGGAAGCGTCGCCGGTACGACAGCTCCTTAACCAATTGTCCGGTGGAGAACTGCACTTATAGGTCGGTTAGGACGGCTATTCCGAAGCATATAGCCGACTCGGAAACCTTGACAGCGTCTAAAGTGCACGTTTTCAAAAAGAAATCCAAAGGGGAGAAGCGCTTCCGCTCGTACTGCTTCTTGTGCTACAAGACGTTGAGGAAGACTATGAGCAGCAGGGAGGCTAACAACAGGATCAATAAGATCCATACGTACTGCGAAGCTTGCAACAAACACATGTgtGGACAAGAATTTCATTGCCCGAACTGCCCGAAGGTGTACGGCAAGAAAAATTCGTTGCGCAAGCATTTGAAGTCGGATTGTGGCAGGGACAAGTCATTCGGTTGTACATTTCCAAACTGCAGCTACAAGAGTAAAAGGAAAGAAAACTTGAAAAGGCATTTAGCTGTACGGCACGAGGTTCCTGGTGGTGTACAATTTCCTTGCCCGAATTGCTCGAAGGTGTACAGCAAGAAGAATTCGCTATACAAGCATTTAAGGTTATATTGCAGCGAAGGCAACTCCTTCGTTTGCACGTTTGTCGGCTGTGGTCATAAAAGTAAAAGGGAGGAGGATATAAAACTGCACGTAGTGAAACAGCACGGGATTCCCAACAGCGACGCCGAAACGTTATACGTGGAGGAATCGACAAATTCGAATCTGGAGTTTCCTTGTCCTGCTTGCTCGAAGGTGTACACCAAGAAAACGTCGTTACAGACCCATTTAAGATTCGATTGCGGCAGAGACAAGACCTTCGTCTGCACGTTTAGCGGTTGCAACCACAGGACTAAAAGGAAGCAGAACCTGAAGAAGCATTTGGTGAAATTGCACGGGGTTCCTTACCAGAACCGTGTTGCATGCCCGCTTCTTGTATCCCGCCCCCGTTACTCACACCTGCGTATTTTAGGACAAAGAATCAAAGAGGAACTGAGGCATATAAATTTCGTCAACAACACCTGTCCAATCTGCCAGAAAGTGTTCAAGAGGAAGGACCACGTCCAACGCCATTACCTGGAGCTGCACATGTTCATGCCGACGCTGGCGTACAAGTGCCCCAAGTGCTCCCAGAAGTTCAAAAGGAGGTACCTGATGGAGAACCACGAAAAGATGTGCGATGGGAGGAATAATGGGCAGTGTTACACGTGCTCTGTTTGCCatgccAGAAAGCAGTACGTCTGCCAAGACTGCAACAGGCCCTTCACCAGACGCGAACACCTGAAACGCCACTACAAAGAGCAACACCTGCAGTCCGAAGGATCCTTTTTCGAGTGCGACGTCTGCAAGAAGAAGTTCAAGAGGAATTACCACCTGAGGCGCCACTATTTGGTTTGCAACGACGCTACCCGCCACCACCAAGTCGAGATCAGGTTCAACTGCAAATTTTGCAACATCTGGTTCAGGGAAGAGGCGGAGTTGTTCGCGCACTGGAACAAGGCGCATCAGGTGTCCAAGAAGGAGTTGCAACTCTAG
- Protein Sequence
- MDEELPDEVLTDLDQLNQWYHLPAENPGGKSAMKRCRWCSKKKIRKRSRYHCPGCEGLPGTQNWICQVCGRRYLHERSLWRHIKYECQKEPSFQCGVCKRLFKLKYHLQSETFCCNACGLLFTSWRSCIKHKKQCLPVATQALTNKAARKYRKSTSKADKVVPLTERKRRRYDSSLTNCPVENCTYRSVRTAIPKHIADSETLTASKVHVFKKKSKGEKRFRSYCFLCYKTLRKTMSSREANNRINKIHTYCEACNKHMCGQEFHCPNCPKVYGKKNSLRKHLKSDCGRDKSFGCTFPNCSYKSKRKENLKRHLAVRHEVPGGVQFPCPNCSKVYSKKNSLYKHLRLYCSEGNSFVCTFVGCGHKSKREEDIKLHVVKQHGIPNSDAETLYVEESTNSNLEFPCPACSKVYTKKTSLQTHLRFDCGRDKTFVCTFSGCNHRTKRKQNLKKHLVKLHGVPYQNRVACPLLVSRPRYSHLRILGQRIKEELRHINFVNNTCPICQKVFKRKDHVQRHYLELHMFMPTLAYKCPKCSQKFKRRYLMENHEKMCDGRNNGQCYTCSVCHARKQYVCQDCNRPFTRREHLKRHYKEQHLQSEGSFFECDVCKKKFKRNYHLRRHYLVCNDATRHHQVEIRFNCKFCNIWFREEAELFAHWNKAHQVSKKELQL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -