Basic Information

Insect: Exephanes ischioxanthus
Gene Symbol: Glis2
Assembly: GCA_958510785.1
Location: OY294017.1:21257951-21261045[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.0053 0.45 11.4 0.2 2 23 146 168 145 168 0.96

2 15 0.00042 0.035 14.9 0.2 2 23 173 195 172 195 0.90

3 15 0.003 0.25 12.2 0.1 3 23 271 291 270 291 0.97

4 15 1 86 4.2 0.4 2 23 297 319 296 319 0.94

5 15 0.00039 0.033 15.0 0.3 1 20 329 348 329 350 0.93

6 15 1e-05 0.00088 19.9 4.4 1 23 360 382 360 382 0.99

7 15 3.9e-05 0.0033 18.1 0.6 1 23 395 417 395 417 0.98

8 15 3.4e-05 0.0029 18.3 2.1 1 23 425 448 425 448 0.97

9 15 4.3e-05 0.0036 18.0 5.5 1 23 454 476 454 476 0.98

10 15 3.3e-05 0.0028 18.4 0.5 1 23 479 502 479 502 0.96

11 15 0.014 1.2 10.1 3.5 1 23 521 543 521 543 0.96

12 15 2.4e-06 0.00021 21.9 1.6 1 23 549 571 549 571 0.97

13 15 1.3e-07 1.1e-05 25.9 2.5 1 23 576 598 576 598 0.98

14 15 4.4e-05 0.0037 18.0 5.7 1 23 606 628 606 628 0.98

15 15 7.3e-05 0.0062 17.3 0.9 1 23 634 656 634 656 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.0053	0.45	11.4	0.2	2	23	146	168	145	168	0.96
2	15	0.00042	0.035	14.9	0.2	2	23	173	195	172	195	0.90
3	15	0.003	0.25	12.2	0.1	3	23	271	291	270	291	0.97
4	15	1	86	4.2	0.4	2	23	297	319	296	319	0.94
5	15	0.00039	0.033	15.0	0.3	1	20	329	348	329	350	0.93
6	15	1e-05	0.00088	19.9	4.4	1	23	360	382	360	382	0.99
7	15	3.9e-05	0.0033	18.1	0.6	1	23	395	417	395	417	0.98
8	15	3.4e-05	0.0029	18.3	2.1	1	23	425	448	425	448	0.97
9	15	4.3e-05	0.0036	18.0	5.5	1	23	454	476	454	476	0.98
10	15	3.3e-05	0.0028	18.4	0.5	1	23	479	502	479	502	0.96
11	15	0.014	1.2	10.1	3.5	1	23	521	543	521	543	0.96
12	15	2.4e-06	0.00021	21.9	1.6	1	23	549	571	549	571	0.97
13	15	1.3e-07	1.1e-05	25.9	2.5	1	23	576	598	576	598	0.98
14	15	4.4e-05	0.0037	18.0	5.7	1	23	606	628	606	628	0.98
15	15	7.3e-05	0.0062	17.3	0.9	1	23	634	656	634	656	0.98

Sequence Information

Coding Sequence: ATGGATGTCAAGGAGGAGAATACAGCAGAACAAACCTCCCGTACGCTAGTTATCACAGGAGAGCAGGATACTTGCCGATTGTGTGGAAAAGCTGGTTCCGACTATACACCAATTTTTGACAATGACGACTTGTTCATTGCGGAAAAAATTGGTAGATGTCTACCGATTGTTgTATTATCAAGCGACGATTTACCGTCGCACGTTTGCCCGAATTGTCTTGAAAGTCTAAACGTGAGCTACGAGCTCATCCTTACGTCGGTAAAAATCGATTCTCAATTGAGGCACCAACTCGCCGAATTTAATGAGAAGGGTGATGCCACTGACCTGACGAATGATTCCGAGGTCACCAAGCTATCGGACAAATTGAATCCCGACGATATTATCGTCACGTGCACAGAGAGACTGCTGAATACCGAAGCGATATATGGTCCAATGGAGTGCGAAAtgtgtttgaaaaaattcgtggACATGAATGATTTCGATCGGCACATAGAGACCGAACATTTGTTGGCCTGGCCGTGCAGTCTGTGCGACAAGAGTTTCGAGACTTCTGTGAAACTGATCTCTCACAAGGAGGAAATGCACGCCGGAAATGTTCTAATTTGCAGTCGCTGCATCGACCATGAAAGATCGGCGCACGGTTTGACTTCACTAGCGGAAATGCAAGACAGTCGTAGGCAAATAACTCGAGTAAAGCGTGTCAGGACGAGAgggcggaaaaaaatcaatgaggCGCATGAACGTAGCGCGAGTAACGAGAAGATCGAAGAGCCGGAAGAAGAGAAGACCGACGCGAAGCCGGTAGCGATGTGCGATATATGCAAAATAGATTTCGGCTCTGACGATCTTTTGACCGCTCATCGACGAatacacgagaaaaaaattcttcaatgCTACTTATGTCAGACCGATGCCTCGTCGATTTACGAACTTTACAATCACAAACGCGAAACTCACAACGTTTATAAGAAGGTTCAATTGAAATTCGTTTGCGACACTTGCGGAAAGTTTTTCTCAAACAACTGGCAGTGGCTCGAACATCGAGAGAAAACCTCATGCAAGAGAACATTGTCCACTTACACTTGCAAATATTGCAATAATGATTTCACGACGAATTTTAAACTCACGAGACACTTGAGAACTCACAAAGACGAAATGCTGAAAGATCCTTCCGCGACGATTTATCGATGCGTCGGATGCCCGAAAATATTCGTCGACAAAGAGTTCTACCAGAAACATCGCAACGTTCACGATCCCGAGTGTTGGGACAAATTCAAATGCGAAAAGTGCAGCAGATCGTTCAGAGATCAAATGCGGTTGCGTGAGCATCAGCAGTCTGTTCACGATGGTTTTAAGCCGCATCAGTGCGATGTTTGCGGCAGAACATTTCATCGATTGTCGAATATGCGAGTCCATCGGAAGAAGCATTTCGGTTACAAGTGCGAGCACTGCGACGAAATTTTCGAGCAGCTGCGAACACTGACGGATCACATAAACGCCGTACACGAAGTGGAACCAAGTCCCAAGCGCGTACCGAAAAAGCCGCAAACCAACGAATGCTTCGTTTGCAGATATTGCGGAAGAAAATTGACCACCCATCAGTCTCTGCTGGATCACGAGCACATTCATACAGGCGAAAAGCCACATTCCTGCAAGATATGCGGAAAATCTTTCAGaaGTTTGTCAGCGAGGTGGGCTCACATGCAGCGTCACGTTAAAGGAACTTATATTTGCGAGCACTGCGGGAAGTCCTTCAGCTATAAGCAGAATCTGACGACACACTTGCAAGTGCACGCACCTGTAGAGAGTCGGAAGCATCGGTGTTCCAAGTGTGGAAAATTGTTTCTTCGGAAATCTCATCTCAAAGTTCACATGCGGATACACGACGGTGTGCGACCGTACACGTGTGACATATGCCAATTCAGTTTCACGCAGATTGGCGATATGAAACGTCATCGGGCGCGTCACGCAAACGGTGAAATTCGTGTGAGACAGCCGCGACCCAAGGCTAGCACAGCTTCCGGTAGTGAAGCAGATGGAAGTTAG
Protein Sequence: MDVKEENTAEQTSRTLVITGEQDTCRLCGKAGSDYTPIFDNDDLFIAEKIGRCLPIVVLSSDDLPSHVCPNCLESLNVSYELILTSVKIDSQLRHQLAEFNEKGDATDLTNDSEVTKLSDKLNPDDIIVTCTERLLNTEAIYGPMECEMCLKKFVDMNDFDRHIETEHLLAWPCSLCDKSFETSVKLISHKEEMHAGNVLICSRCIDHERSAHGLTSLAEMQDSRRQITRVKRVRTRGRKKINEAHERSASNEKIEEPEEEKTDAKPVAMCDICKIDFGSDDLLTAHRRIHEKKILQCYLCQTDASSIYELYNHKRETHNVYKKVQLKFVCDTCGKFFSNNWQWLEHREKTSCKRTLSTYTCKYCNNDFTTNFKLTRHLRTHKDEMLKDPSATIYRCVGCPKIFVDKEFYQKHRNVHDPECWDKFKCEKCSRSFRDQMRLREHQQSVHDGFKPHQCDVCGRTFHRLSNMRVHRKKHFGYKCEHCDEIFEQLRTLTDHINAVHEVEPSPKRVPKKPQTNECFVCRYCGRKLTTHQSLLDHEHIHTGEKPHSCKICGKSFRSLSARWAHMQRHVKGTYICEHCGKSFSYKQNLTTHLQVHAPVESRKHRCSKCGKLFLRKSHLKVHMRIHDGVRPYTCDICQFSFTQIGDMKRHRARHANGEIRVRQPRPKASTASGSEADGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00905579;
90% Identity: iTF_01364841;
80% Identity: -