Epin002945.1
Basic Information
- Insect
- Euzophera pinguis
- Gene Symbol
- ZFX
- Assembly
- GCA_947363495.1
- Location
- OX376182.1:1180588-1188948[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00056 0.044 14.9 6.2 2 23 286 307 285 308 0.95 2 13 0.077 6 8.1 3.7 1 23 314 336 314 336 0.91 3 13 0.68 53 5.2 1.3 1 23 340 362 340 362 0.96 4 13 0.044 3.4 8.9 6.0 1 23 367 389 367 390 0.95 5 13 0.11 8.4 7.7 0.2 1 21 425 445 425 446 0.91 6 13 0.13 10 7.4 0.2 3 23 453 474 452 474 0.88 7 13 2.1 1.7e+02 3.6 0.7 3 19 483 499 483 501 0.96 8 13 0.93 73 4.7 0.0 2 23 508 530 507 530 0.94 9 13 7.2e-05 0.0056 17.7 1.1 1 23 536 559 536 559 0.94 10 13 6.6e-07 5.1e-05 24.1 0.4 1 23 612 634 612 634 0.97 11 13 4.5e-06 0.00035 21.5 4.5 1 23 640 662 640 662 0.99 12 13 5.6e-05 0.0044 18.0 0.7 1 23 668 690 668 690 0.99 13 13 9.4e-05 0.0073 17.3 0.7 1 23 696 719 696 719 0.95
Sequence Information
- Coding Sequence
- ATGTGGTCACAAGATGTTAAAAGTGGCACAGATGCCCTGGCATGCCGAGGATGTCTCACTTCTAGCGTAAAATTATTTAGCATCGAAGAAAACAATTTGGTCGACAACTACGTTACACTGGTTGGGATTTCGCTGGAAGATAATTACAGCCACCACCTGTGCGGTATCTGTGCAACGATGCTACTCAAGTTCTGCTCGTTCAGGGAGAGATGTCTTATGGCTTATCATCTACTCATGGACGCAGACTATCATGAGAAAGACATAACAGAATATATTGAAGTCCCAAACATACGTACATACAGTAATCAGCTAACATTGCCTTACGCACACAGCAAAGTCCAGACACGAAATTATGTACCCTTGGAGTATATGAATGACGAAGTTAGGATAGAAGTTATCGGCTCAGATTTGTCTAGAACCTTCACTACATTAGATGATTTGAAACGGGATAATGTAACAAAAGTTAATAAAATGGAGATCAAAATGGATGGTAAAATAGAAATTGATACTGTTGATAGCAAAGCAAATGTAAAAAATGAAAGTGTAGATGATGACTTTGAGGTAAGTAAAGGAGATAATGACGATGAATTCTCAGACTCTGAAGATGACGCTACAGTATTTGAGACGGGAATAAAGGTAGGCAAAAGTGATAATGATTCTACAGATGAAGATACCATTAAAAAAAAGGTTCCAAAGAAAAAAAGTGCTAACAAAAAGATGGTAGCGAATAAGAGACCGAAAACGGATCAAGAAATATTAGAATATATTAAACCGTTCAAATTCGAAGTGACATTTTTAAATGAAAAGGAACAATTTGCAGAGATTGAAGCAAAGAAATCAAACTTACAGCCGAATCAGTGTGAGTTATGCGGAAAAAAGTTTAAATCCTCTTACTGTTTTAATCGACATAAAGAAATTCATCATGACAGTAATATAAAATACGATTGCAATATTTGTCATTTAAGATTTAATAATCACTTTGGATACTTAAGACATAAAGGGGCACACGGAGTGTTGTATAAATGTACAACGTGTCAGTTTCAAACTAAAAGAGTAGAACTTTTAGAACCACACTATTTGCGCCATCAAGGAAAGATACATGTATGTGAACATTGTTCCAACAATTTCAAATCGCGGACAGCATATTTGACGCATGTTAGAATACATCATGCTTCGATATTACCGTGGTGTGAGTTATGTGGGGAGGCGTTTCTTAATGAAAAAGGGATTTTTTATCATAAATCGAAAGCGCATAGAGGTGTGAAGGTTGAATTTCCTTGTTCGGGTTGCGGGGTTAAGTTTAGTTGTGAGTCCGCTTTGGATTTGCATGTGAGGAGGGAGTGTGGTTTGGAGAACTGTGTGCAGTGCGGGGAGGGGTTCCAGACTGATCAGTTGCTGAGGAAGCATGTGGTGCAGACACATAGCATTGAGATACCGATGATTGGGTGCGAAGGATGCGCCGTAAAATTCCATAACACGAAAGCGCTACAGAAACACAACCAGTGTTGCGGGTCGGGCGTGCCGTGCGCGCAGTGCGGCGGCCATTTTGATAATGACGCGCTGATGTTGGAACATGTTAGGGTGGAGCACAGTGGTGGGACGGACTTCCTGTGCGTTGGGTGTGGTAAAAAGTTTACTAACGCTTTTCACTACAGGGACCACATAATTAGAGTTCATCAGAAGCCCAATACACAGTGCATCCAACAGACTACCCGTGCCCGTCGCAAACGCACCGTACGTTCGGATCGTAATGACGAAACTAGAAAATGGCGACCGGTGGGAGAAGAGGAAGTCGCGATGGAAACTAAGAGGAAAAAGGGCGGGAACGGAACGCACATGTGTGAAGTCTGCGGATGGGTGTTTAAGGATGTAAGCCAACTGAAGACACATATGGCTACACATAGCGACGCCAGACCGTTCCAGTGCTCGCATTGCCCGAAGACATTCAGAACACATGCGTCACTCGAAATGCACACGCGCGTACACACTGGCGACCGGCCATATAAATGCGAAGTGTGTCTTAAGACATTCAAAATATATACCGGGTTGAATCGACATATGCTGATACACACGGGAGAACGGAAACATATCTGCCAGATTTGCGACAAATCATTCCCAACGTCTACTGGTGTTAAAATGCATATTAAAAATGTTCACTTAAAAATACCTTACCCTAAACGGAAGCGGAAGGTTAATTAG
- Protein Sequence
- MWSQDVKSGTDALACRGCLTSSVKLFSIEENNLVDNYVTLVGISLEDNYSHHLCGICATMLLKFCSFRERCLMAYHLLMDADYHEKDITEYIEVPNIRTYSNQLTLPYAHSKVQTRNYVPLEYMNDEVRIEVIGSDLSRTFTTLDDLKRDNVTKVNKMEIKMDGKIEIDTVDSKANVKNESVDDDFEVSKGDNDDEFSDSEDDATVFETGIKVGKSDNDSTDEDTIKKKVPKKKSANKKMVANKRPKTDQEILEYIKPFKFEVTFLNEKEQFAEIEAKKSNLQPNQCELCGKKFKSSYCFNRHKEIHHDSNIKYDCNICHLRFNNHFGYLRHKGAHGVLYKCTTCQFQTKRVELLEPHYLRHQGKIHVCEHCSNNFKSRTAYLTHVRIHHASILPWCELCGEAFLNEKGIFYHKSKAHRGVKVEFPCSGCGVKFSCESALDLHVRRECGLENCVQCGEGFQTDQLLRKHVVQTHSIEIPMIGCEGCAVKFHNTKALQKHNQCCGSGVPCAQCGGHFDNDALMLEHVRVEHSGGTDFLCVGCGKKFTNAFHYRDHIIRVHQKPNTQCIQQTTRARRKRTVRSDRNDETRKWRPVGEEEVAMETKRKKGGNGTHMCEVCGWVFKDVSQLKTHMATHSDARPFQCSHCPKTFRTHASLEMHTRVHTGDRPYKCEVCLKTFKIYTGLNRHMLIHTGERKHICQICDKSFPTSTGVKMHIKNVHLKIPYPKRKRKVN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -