Elap012771.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Euura lappo
Gene Symbol
topi
Assembly
GCA_018257835.1
Location
JAEUYN010000404.1:25721-28639[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.066 8.6 7.8 1.3 1 23 253 275 253 275 0.95
2 16 3.5 4.5e+02 2.4 1.3 2 23 282 304 281 304 0.82
3 16 0.00062 0.081 14.2 0.4 2 21 311 330 310 331 0.92
4 16 8.7e-05 0.011 16.9 0.7 1 23 338 360 338 360 0.97
5 16 2.5e-06 0.00032 21.7 2.1 1 23 366 388 366 388 0.98
6 16 0.0023 0.3 12.4 0.7 2 23 400 421 399 421 0.97
7 16 0.018 2.3 9.6 1.8 1 23 437 459 437 459 0.95
8 16 0.025 3.2 9.1 1.3 1 23 465 487 465 487 0.95
9 16 0.023 3 9.2 0.7 1 23 497 520 497 520 0.96
10 16 0.71 93 4.6 0.1 3 19 536 552 534 555 0.82
11 16 0.0091 1.2 10.5 0.1 1 23 560 582 560 582 0.98
12 16 2.3e-06 0.0003 21.9 3.1 1 23 588 610 588 610 0.98
13 16 0.00014 0.019 16.2 0.4 1 23 616 639 616 639 0.97
14 16 0.073 9.5 7.7 0.6 1 23 645 667 645 667 0.85
15 16 3.6e-07 4.7e-05 24.4 2.2 1 23 673 695 673 695 0.99
16 16 6.9e-06 0.0009 20.3 4.9 1 23 701 724 701 724 0.96

Sequence Information

Coding Sequence
ATGCTGAAAGCCGATTCTTCGTCTTTGAGCACTATGAGCAACGACGATGACGAGATCGACGACTTGGACGGCTCCATGGTGTGGAGTCAGGAAGACTCGCTATCCGCCAATGAGATTATGGAACTTGAGGCTCCCATGAGGGCTTCAGGGCCCGGCGGAGACGCCGACTGCGCTGCACTGTGCAGACTATGCGCAGGCATTGCCGTTAATCCTATATACATATACTCCGAGATGGGGGAGTCGATGAAACTCGCACATAAAGTCAACACCTGCCTCAGCGTCAAGATCCGGAGGACCGATCCCCTACCGAAGCAGCTGTGCCTGACCTGCGCGGAGAAGATAATGTACTGCGACGAGTTTGACACCCAATGCGTCAGGGCGGAAGAGACGCTGCTGACGCTGTTGCGAGAGAAAGAGCGCCACGACATCCCGGAGCTGATAACGCACGAGATATTATGCGACGAAAAATCCTGTCCGCTGTGTCTCGACGGGTGCATGACGACGAGTAAACCGAACCTGGTGGACCCCAGCTGCCAGGATCTGTACGACAGCGACCTCGTTCTGGACAGCAGCGACGAGGAGAGAGCCTTCCAAGTTGTAACCGCGGACCGAGACTCGGGGAACTCGATAATGCTTCAATGCCTCGGAAACCGGCAGCAGTACCTGAAGTGCGGGGCCTGCATGAACCTCTATCACACCAAGGAGACCCTGGACAGCCACAAGTGCAAACCCAACGTCCAGAGCACTTCCAAACCGTACAAATGCCCGACTTGCGCGATAACTTTCACTTTCGAGGAGCGGCTGAACTTCCACATGCAGTTTCACGCGGGGTCCAAGGCGCTCTACTGCGGGGTGTGCAACACCACTTTTGGGAAGGAGCTGAAACTGTTCTTCCACTACAAGCGATACCACTGCGAGGATTCGAGCGTCTCCTGCCTCCAGTGCGGAAAACTGTTCGAGAACCAGGAGGAACTCAAGAGACACGTTTGCGTCGACGGCAAAGTCAGGCCTCACGTCTGCGAGGTCTGCAGCAAGGGCTTCTCCGACGGCTACACGCTCAAACGACACGTCGTTACCCACCTCCCTGAGAAACCGTACAAATGCGGTCAATGTCAGAAGAGTTTTACCCAGAAATCGAGGCTCAATAAACACGTGGCGAGCCACGGAGTCGTCATCGAGGAATCGCAGACCGTTTGGAAGTGCGTCGAGTGCGGCGAGGCCTTCACGACGTGCGAGGACGCGGATAATCACTACAAAAAACACGACGATAAGATAACGCTGATAGAGGAACTGGTGGCGAGCAAAATCTACCACTGCGAATTCTGCAACAGCTTCTTCACGGAGCTGGACGCCCTCAAGAATCACCAGGGTCTCCACGTGGTCGAGAGACCGTATTTCTGCAACCACTGTCAAACCTCGTACAAGTCTTACGCAGAGGCCGTGATCCACTGGAAAGAGCACCCGAGGATATTCAAAATCGCCGTATCGTTCTCCTGCGAGATTTGCGGGAAGGACATGAAGGAGCTCGCCCTGCTCTACAAGCACAAGCAGAAACGGCACCGCTTCGTGCCCCGGAAATCCGAGAGCGGGGACCAGAAATTCGGCTGCGAATTGTGCGGCCGCGTTTTTGACGCCTTTTCCGAGATCGAGGAGCACGGGAAGCAGCAGTGCTCCAAATTCCCCTGCGACGTGTGCGGCAGCCTCTTGCCGACCGCCAACTCGCTCAACGCTCACAAGCGGAGGCACAGCGGGCTCAGACCGTACGTCTGCAATATTTGCGGCAAGAGCTACACCCAGTCGAGCCACATGTGGACGCACAAGAGGTTCCACATGGGGGTGAAGCCGTACGCTTGCGAATACTGCGACCAGAGGTTCACCATCAAGCCGGACCTCGCCGATCACACCAGGAAGAAGCACACCAGGGAGAGACCGTTCAAGTGCGACGTCTGCAACAAGGCTTTTCTCACCGGATCCGTGTACTATCAGCATAGACTGATACACAGGGGCGACAGACGGTACAAGTGCCACTATTGCGAGAAGGCCTTCACCAGGACCGAGGCGCTGAACAATCACATAAAAATTCATACCGGGGAGAAACCGCACGCTTGCGATGTTTGCGGAAGATGTTTCAGGCAGAAGGGAGACATGCGAAAGCACAGGAGAACCCAGCATCTCGATAAACATGAATCTTGTTGA
Protein Sequence
MLKADSSSLSTMSNDDDEIDDLDGSMVWSQEDSLSANEIMELEAPMRASGPGGDADCAALCRLCAGIAVNPIYIYSEMGESMKLAHKVNTCLSVKIRRTDPLPKQLCLTCAEKIMYCDEFDTQCVRAEETLLTLLREKERHDIPELITHEILCDEKSCPLCLDGCMTTSKPNLVDPSCQDLYDSDLVLDSSDEERAFQVVTADRDSGNSIMLQCLGNRQQYLKCGACMNLYHTKETLDSHKCKPNVQSTSKPYKCPTCAITFTFEERLNFHMQFHAGSKALYCGVCNTTFGKELKLFFHYKRYHCEDSSVSCLQCGKLFENQEELKRHVCVDGKVRPHVCEVCSKGFSDGYTLKRHVVTHLPEKPYKCGQCQKSFTQKSRLNKHVASHGVVIEESQTVWKCVECGEAFTTCEDADNHYKKHDDKITLIEELVASKIYHCEFCNSFFTELDALKNHQGLHVVERPYFCNHCQTSYKSYAEAVIHWKEHPRIFKIAVSFSCEICGKDMKELALLYKHKQKRHRFVPRKSESGDQKFGCELCGRVFDAFSEIEEHGKQQCSKFPCDVCGSLLPTANSLNAHKRRHSGLRPYVCNICGKSYTQSSHMWTHKRFHMGVKPYACEYCDQRFTIKPDLADHTRKKHTRERPFKCDVCNKAFLTGSVYYQHRLIHRGDRRYKCHYCEKAFTRTEALNNHIKIHTGEKPHACDVCGRCFRQKGDMRKHRRTQHLDKHESC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00175246;
90% Identity
iTF_00719641;
80% Identity
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