Basic Information

Insect: Eustalomyia histrio
Gene Symbol: grau
Assembly: GCA_949748255.1
Location: OX456527.1:65475867-65478091[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.92 96 5.2 0.4 6 23 325 342 325 342 0.96

2 9 3.9e-05 0.0041 18.9 0.6 1 23 348 371 348 371 0.96

3 9 0.0016 0.16 13.9 1.0 1 23 381 403 381 403 0.97

4 9 7.1e-05 0.0075 18.1 0.1 1 23 411 434 411 434 0.95

5 9 0.00015 0.016 17.1 1.0 3 23 442 462 441 462 0.97

6 9 0.0029 0.3 13.0 0.2 2 23 471 493 470 493 0.90

7 9 0.00013 0.014 17.3 1.7 1 23 501 524 501 524 0.96

8 9 1.2e-06 0.00013 23.7 0.6 1 23 530 552 530 552 0.98

9 9 0.00056 0.059 15.3 2.6 1 23 558 581 558 581 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.92	96	5.2	0.4	6	23	325	342	325	342	0.96
2	9	3.9e-05	0.0041	18.9	0.6	1	23	348	371	348	371	0.96
3	9	0.0016	0.16	13.9	1.0	1	23	381	403	381	403	0.97
4	9	7.1e-05	0.0075	18.1	0.1	1	23	411	434	411	434	0.95
5	9	0.00015	0.016	17.1	1.0	3	23	442	462	441	462	0.97
6	9	0.0029	0.3	13.0	0.2	2	23	471	493	470	493	0.90
7	9	0.00013	0.014	17.3	1.7	1	23	501	524	501	524	0.96
8	9	1.2e-06	0.00013	23.7	0.6	1	23	530	552	530	552	0.98
9	9	0.00056	0.059	15.3	2.6	1	23	558	581	558	581	0.98

Sequence Information

Coding Sequence: atggaagctTGCTTATTATGCCTAGAAATAAACAAAGAATTAttgaattccatacaaataaattCAGACAAGTGGCAAGAACTTAATATAAGGAAACttatagaaaaacatttatgGCCAATTGATTATATGGAATCTTATTCTTGGCTTTGCAAAGAATGCTGGGAGGAATTGCACAATTTTAACATATTCTACCAACGCATAGAGGAGGCTCATATGGATTTTGGAAAACTCACGAAAACAGACGAAATAAATCAATTCTTAGAAcataagcttatattaaaaaatgaatcatataataaaccaaaaatCTGTTTAGAACCAGAAATATTAATAGATATATCTTCACAACAACCATTGATAATGCCCGAAGAAAAACTTGTCATCAAAGAAGAAATACAGCAAGATTCTGATGATGACAGTATGATCGTAAAGAAACAACCAAGCCGAAAACGTGTTAGCAAAGATTTCATCGAGCAACAAGAATTGTCAATGAAAGATCCTTtggagaaaactaaaaaaaccaaaataaataaaagacaaaCCGCAAACcctaaaagtaagaaaataaaatctacTAAAAACTTGAATACCTTAagtgaaactttaaaaaaagatgAAATAGACCAGCCCAATATAAAGCGGGATCCAGATTTATTTGTTAACAATCAAGAACCTATCGTAGCACTTAAATATTGCACTAACGATGATAACGAGAGTAATTATGATGATTCAGATTCTGAATCTAACTATGAACCAGATAAAAATCGTCTTGAAAGTACCGAAGAAAATGAGTCACAAAAAAGTTCACATTATAAACCTCGTACAAATCGTAAAGAACAAGATAAATTAATATCtgtaacatttaaagaaatCTTGTGCGACCTTTGTCAATTTCCAATGTCTAATTTTAGCGTCGTACATAAGCATTTTATCGAAAAACATAATGCTCAGAAAGGTTACGTTACGTGTTgtagtagaaaattttcttcTCGGACACGTTTGGTTGATCATATCGATTATCATAAGAATCCCGATcagtttaaatgtaaacaatgtGGTAGAGAATTAGCCGATAATAGCCGTTTAAAACGTCACATGATATATGTACATGGAGAGGGTGGTGAGATAATTAAGAGACATTCTTGTGATGTCTGTGGAAAATCTTTTTTAGGACCTTTTGAATTAAGAAATCATAAGATGTCGCACTTGTCGCAAGAGGAGAAAAAGTTTCCATGTGCGGAATGTGGAAAATTTTATGCTAGTACTTCTAAACTAAATAATCATATACAAGCTGTacatctcaaaaaatttgttaaaatttgccaCATATGCGGAAAATCTACAAGTTCTACTACGGAATATAACGCTCATATTGAAAAGCACGAAGGGAAACCAGCTCCCAATATAAGCTGTGACATTTGTGGTCTTCGTCTTACTTCACAAAGGGGTTTAAAACGTCACAAAGAAGCCCAACATCCAGAAGGAGGAAAAAAAGACCACTGTTGTCCCATTTGTCCGAAAGTTTCGCCAACTCTAAAGGCTCTTAAAAAGCATATACAAAGAATGCACGAAAAGGGTCGTGAACACAAATGTACAATATGTGAAAAAGCCTTTAGGAGGGCAGAAGCATTGAAGgaacATATGGCTTCACATACTGGAACTTCTTTATATACTTGTACTTGGTGCCCAAAGACATTTAACGCCAATGGTAATATGCATTCACATCGTAAAAAAATGCACCCAATCGAATGGGAGGAggaacagttaaaaaaatattctggaaACTTACCACCACAATTTCGAAAATCTTATGAACACTAA
Protein Sequence: MEACLLCLEINKELLNSIQINSDKWQELNIRKLIEKHLWPIDYMESYSWLCKECWEELHNFNIFYQRIEEAHMDFGKLTKTDEINQFLEHKLILKNESYNKPKICLEPEILIDISSQQPLIMPEEKLVIKEEIQQDSDDDSMIVKKQPSRKRVSKDFIEQQELSMKDPLEKTKKTKINKRQTANPKSKKIKSTKNLNTLSETLKKDEIDQPNIKRDPDLFVNNQEPIVALKYCTNDDNESNYDDSDSESNYEPDKNRLESTEENESQKSSHYKPRTNRKEQDKLISVTFKEILCDLCQFPMSNFSVVHKHFIEKHNAQKGYVTCCSRKFSSRTRLVDHIDYHKNPDQFKCKQCGRELADNSRLKRHMIYVHGEGGEIIKRHSCDVCGKSFLGPFELRNHKMSHLSQEEKKFPCAECGKFYASTSKLNNHIQAVHLKKFVKICHICGKSTSSTTEYNAHIEKHEGKPAPNISCDICGLRLTSQRGLKRHKEAQHPEGGKKDHCCPICPKVSPTLKALKKHIQRMHEKGREHKCTICEKAFRRAEALKEHMASHTGTSLYTCTWCPKTFNANGNMHSHRKKMHPIEWEEEQLKKYSGNLPPQFRKSYEH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00717048; iTF_00717028; iTF_00717060; iTF_00717031; iTF_00717075; iTF_00717099;
90% Identity: iTF_00717048; iTF_00717060;
80% Identity: -