Ehis041857.1
Basic Information
- Insect
- Eustalomyia histrio
- Gene Symbol
- grau
- Assembly
- GCA_949748255.1
- Location
- OX456527.1:65464109-65465946[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 8.5 8.9e+02 2.1 0.7 6 23 198 215 198 215 0.95 2 9 0.00045 0.048 15.6 1.1 1 23 221 244 221 244 0.96 3 9 5.5e-06 0.00057 21.6 1.4 1 23 254 276 254 276 0.97 4 9 0.0026 0.27 13.2 0.5 1 23 284 307 284 307 0.94 5 9 3.5e-05 0.0037 19.1 1.0 3 23 315 335 314 335 0.97 6 9 0.0083 0.87 11.6 0.2 2 23 344 366 343 366 0.90 7 9 0.00035 0.037 15.9 3.3 1 23 374 397 374 397 0.96 8 9 9.1e-07 9.6e-05 24.1 0.7 1 23 403 425 403 425 0.98 9 9 5.4e-05 0.0056 18.5 3.3 1 23 431 454 431 454 0.98
Sequence Information
- Coding Sequence
- ATGTTGGTAGATCAATCTCCGCAACAAGAATTAATAATGCAAGAAGAAAATCTTGTCATCAAAGAATTACCTCAAGATTCTTACGCTGACAGTATGATGGTAAAGAAACAACCAAGCCGAATAcgaaagcaacaaaaattgtcaaTGATAGATCCTttggaaaaaactaaaaaaacaaaactaaataatgGACAAAACGCAATACCTAAAAGTAAGATAATAAAGCctactaaaaacttaaatactttaATCGCATCCTTAAAAAGAGATGAAAATGAACATTCCAATATAAAGCAGGATCCAGATTTCTTTGTTAATTACGAGAATGATTATGATCATGATGACAATGATTCAGATTCTGAATCTATCTATGAACCAGataaaaatggtattgaaagtaaagaaaaaaataaatcacaaaaaagTTCACATTATGAACCTCGTACAAATCGTAAAGAACAAGATAAATTAATATCtgaaacatttaaagaaatCTTTTGCGATCTTTGTCAATTTCCAATGTCTAATTTTAGCGTCGTACATAAGCATTTTATCGAAAAACATAATGCTCAGAAAGGTTACGTTACGTGTTgtagaagaaaatttttttctcggaCACGTTTGGTTGATCATATCGATTATCATAAGAATCCCGCTCAATTTATATGTAAGCAATGTGGTAGAGAATTAGCAGATAGCGTTGGTTTAAAACATCACATGATGCATGTCCATGGAGAGGGTGGTGAGATAATTAAGAGACATTCTTGTGGTGTTTGCGGGAAATCATTTGTAAAACCTTCTAAATTAAGAGATCATAAGTTGACGCACTTGTCGCAAGATGAGAAAAAGTTTCCATGTTCGGAATGTGGAAAATTTTATGCCAGTACTTATATACTAAACCATCATATACAAGCTGTAcatctcaaaaaatttgctaaaatttgccatATATGTGGAAAATCTATAAGCTCTAATACAGAATATAAAGCTCATATGGAAAAGCACGAAGGGAAACCAGCTCCCAATATAAGTTGTGATATTTGTGGTCTTCGCCTTACTTCAGAAAGGGGATTAAAACGTCACAAAGAAGCCCAACATCCAGAAGGAGGAAAAAAGGACCACTGTTGCCCTATATGCCCGAAAGTTTCGCCAACTCTGAAGGCTCTTAAAAAACATATACACACAATGCATGAGAAAGGGCATGAACACAAATGCACAATATGTGAAAAAGCTTTTAAGAGGGCTGAAGCATTGAAGGAACATATGGCTTCACATACTGGAACTTCTTTATATACATGTTCTTGGTGTCCCAAGACGTTTAACTCCAATGGTAATATGCATTCACATCGCAAGAAAATGCATCCAATCGAATGGGAAGAGatacagttaaaaaaatattctggaaGCTTACCGCCACAATATCAAACAAAAGATGACTATAACTTTTGA
- Protein Sequence
- MLVDQSPQQELIMQEENLVIKELPQDSYADSMMVKKQPSRIRKQQKLSMIDPLEKTKKTKLNNGQNAIPKSKIIKPTKNLNTLIASLKRDENEHSNIKQDPDFFVNYENDYDHDDNDSDSESIYEPDKNGIESKEKNKSQKSSHYEPRTNRKEQDKLISETFKEIFCDLCQFPMSNFSVVHKHFIEKHNAQKGYVTCCRRKFFSRTRLVDHIDYHKNPAQFICKQCGRELADSVGLKHHMMHVHGEGGEIIKRHSCGVCGKSFVKPSKLRDHKLTHLSQDEKKFPCSECGKFYASTYILNHHIQAVHLKKFAKICHICGKSISSNTEYKAHMEKHEGKPAPNISCDICGLRLTSERGLKRHKEAQHPEGGKKDHCCPICPKVSPTLKALKKHIHTMHEKGHEHKCTICEKAFKRAEALKEHMASHTGTSLYTCSWCPKTFNSNGNMHSHRKKMHPIEWEEIQLKKYSGSLPPQYQTKDDYNF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -