Ehis027939.1
Basic Information
- Insect
- Eustalomyia histrio
- Gene Symbol
- grau
- Assembly
- GCA_949748255.1
- Location
- OX456525.1:98805618-98821977[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 9.8e-06 0.001 20.8 2.7 1 23 162 184 162 184 0.98 2 12 0.013 1.4 11.0 3.5 1 23 190 213 190 213 0.98 3 12 0.015 1.5 10.8 1.8 1 23 252 275 252 275 0.96 4 12 0.00055 0.057 15.3 4.3 1 23 305 328 305 328 0.97 5 12 0.0024 0.25 13.3 1.2 2 23 379 401 378 401 0.92 6 12 5e-05 0.0052 18.6 2.5 1 23 434 456 434 456 0.99 7 12 8.9e-05 0.0093 17.8 0.2 1 23 462 484 462 484 0.94 8 12 0.00084 0.088 14.7 0.2 1 23 490 512 490 512 0.95 9 12 0.0081 0.85 11.6 2.7 1 23 518 540 518 540 0.95 10 12 0.2 21 7.2 2.2 2 23 551 573 550 573 0.93 11 12 0.02 2.1 10.4 0.9 1 23 583 605 583 605 0.98 12 12 0.0042 0.44 12.5 0.6 1 23 611 634 611 634 0.97
Sequence Information
- Coding Sequence
- ATGTGTCCAAAATCAGCTTTTTGTCGGCTATGCCTTTGTTCTAGTACTGAAGTTAAAGAGTTAATTAATGAAAATGGCCAATACAATAATGTTTATGAAATCACTGCGAAATATTTTGATCCAATGTTATTAACAACGGTAATATGTGTGGATTGTTGGcaacatatttttgaattttatgaatttcaacaaTCTGTGCTTAAGGCTCAGGCAAATCTTGAAGGTAGTGAACAAAACGAGCCACTTGTTAAAATGGAAATGGTACTACTAGACCAAGatgaaaatgttgaaataaaagaACTAAAAGGAGATGATAAATCATCGCTATTCGATTCAGTGGACTTGAGTGATTATAATCCATTTATTTCTGATGCAGAAGTGCCATTAGCTGAATATTCCacccaaaatatttcaataataaattgtaAGGAAGAAACTATTTATCCTGTTTCTTATGATACTCTCAATCAGGatgaatacaaatttaagtgCACCTTATGTGATAAATCATTTAAGCTTGCCCGTAATTTACGTCAACACACAACTACACATACTGGGCAGGCCTTATATCAGTGTCCGCTTTGTTCGACGAAATGTACACTGTATAAAAACATTCGTCGTCATATACAAAAACTTCATCCTAAAGAATTTGTTGACTTGGGttataatcaacaaaatgttttaaccaAACTATATTCAACATTAAAAGAAGAATCTATTCAGCCTAACTATGACGACGATGATAAAGGTAAATTTAAATGTCCCTATTGCAGGTCAAAAGTTTCACATCAAAGAAATCTTCCTCGTCATATTAAAGCACTACATCCTGAGAAATATGACGAATATTTAgtagaaattcaaaatttaaaattaaagcaagaATCTGATAATGATGCTGATGATatgcataaatttaaatgtcCCCATTGTCAgaggaaatttttacaaaagaaaaacattcgGCGTCACATAAGATTATTACATCCTGATATCTACGTCGAGCCTACCATAGATACTGCAAGAgttgatttaaatttgttagGAAATCATGGAGAAAAAAGCGAAACTATTGACGAAGATTTGCCCAATTATGATGATTATGATGCATTCATAGCTAAATGGAAAGAAGATTTAGAATGTTATCTATGTAAAAAAACATTCATCAATTTCGGCTTATTACGTAAACATTTCAAGGATGAACATCcaaataataaatgttatataaaatgttgtGAATATAAAATACCGTCTCGTATCAGATTAGTAGATCACATACGTTTTCATCTGGATCGAACTTCTTTCAAATGTGATGTATGTGGAAAATGTTTAGGTAATAGTATTTCACTTCATATTCATATGCGATCACATAGCGAAAAAATACGATATGAATGTAACGTTTGTGGAAAAGGTTTTCGAAAAAACTACAAATTGCTGCTTCACGCCGGTATTCATAGCACAGAAATGAACTATTTTTGTAACGTATGTGGTAAGGGATTTTCCATCGAACCTCTTCTTAAAAAACATGAATACATTCATACTCGTAATGCAAAATATCTTTGCGATCAATGTGGTAAATATTGTCATAGCAGCATCGAACTTGAAAAGCATATCCTTCAGCATACTGATATTGAAAATCCTGATTCTAAATGGCCCTGTGATATATGTGGCGCTCTATTTACATCGCGTTCAACTTTcagatttcataaaaaatcatgTCATTCTGATACTGTTTATGTATGCAGTAAATTTAAATGTGCAAAATGCAATAAAGAAGTAATGTCTGCTAAGTCATTGCATGAACATGAAGCAACACACTCTGGATATGCTAAATATCAATGTCCCCATTGTCcgttgaaattaaaacaaaaaaagaatattccTCGGCATATTCAAATTGCACATCCATTGGAATTTAACCAGCTGACTAAACGTAAAAGAACAAAAGtagatttaagtttattagataatcagatggtaatttaa
- Protein Sequence
- MCPKSAFCRLCLCSSTEVKELINENGQYNNVYEITAKYFDPMLLTTVICVDCWQHIFEFYEFQQSVLKAQANLEGSEQNEPLVKMEMVLLDQDENVEIKELKGDDKSSLFDSVDLSDYNPFISDAEVPLAEYSTQNISIINCKEETIYPVSYDTLNQDEYKFKCTLCDKSFKLARNLRQHTTTHTGQALYQCPLCSTKCTLYKNIRRHIQKLHPKEFVDLGYNQQNVLTKLYSTLKEESIQPNYDDDDKGKFKCPYCRSKVSHQRNLPRHIKALHPEKYDEYLVEIQNLKLKQESDNDADDMHKFKCPHCQRKFLQKKNIRRHIRLLHPDIYVEPTIDTARVDLNLLGNHGEKSETIDEDLPNYDDYDAFIAKWKEDLECYLCKKTFINFGLLRKHFKDEHPNNKCYIKCCEYKIPSRIRLVDHIRFHLDRTSFKCDVCGKCLGNSISLHIHMRSHSEKIRYECNVCGKGFRKNYKLLLHAGIHSTEMNYFCNVCGKGFSIEPLLKKHEYIHTRNAKYLCDQCGKYCHSSIELEKHILQHTDIENPDSKWPCDICGALFTSRSTFRFHKKSCHSDTVYVCSKFKCAKCNKEVMSAKSLHEHEATHSGYAKYQCPHCPLKLKQKKNIPRHIQIAHPLEFNQLTKRKRTKVDLSLLDNQMVI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -