Ehis027462.1
Basic Information
- Insect
- Eustalomyia histrio
- Gene Symbol
- zfh1
- Assembly
- GCA_949748255.1
- Location
- OX456525.1:85174749-85180457[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.00085 0.089 14.7 1.6 2 23 205 226 204 226 0.96 2 13 0.00063 0.066 15.1 5.1 1 23 232 255 232 255 0.98 3 13 0.0074 0.78 11.7 1.2 1 23 408 431 408 431 0.98 4 13 4.2 4.4e+02 3.1 0.9 3 23 481 502 479 502 0.87 5 13 0.13 13 7.9 0.1 6 23 512 529 512 529 0.97 6 13 6.1e-05 0.0064 18.3 6.0 1 23 535 558 535 558 0.98 7 13 0.00011 0.012 17.5 1.3 1 23 566 588 566 588 0.93 8 13 0.0013 0.14 14.1 3.4 1 23 594 617 594 617 0.92 9 13 0.0045 0.47 12.4 4.1 3 23 622 642 621 642 0.98 10 13 0.037 3.8 9.6 0.5 1 23 650 673 650 674 0.94 11 13 6e-05 0.0063 18.3 0.1 1 23 680 703 680 703 0.97 12 13 0.00056 0.058 15.3 0.1 1 23 711 733 711 733 0.93 13 13 0.03 3.1 9.8 1.5 1 23 739 762 739 762 0.96
Sequence Information
- Coding Sequence
- ATGTCTCCAACAATTTTGTGTCGGTTGTGCAGgtgttatcaaaataatttcattaaattattcgAAGAAAATGGCCAAAGcaatgaaatttatgaaatcACTGTCAAATATTTTGATCCTCCaatgTTATTGGCATCAGAACAAGGAAATCATTTAACTGCAATATGTTTGGAATGTTGGCatcatattaatgaattttatgaatttcaacagCTTATATATAAGGCTCATGAAAAGCTGGAAAGTATTGAAATCGTACATCTGGATGAGAAAATTGAACATGAAGaaaataatgAAGATAATAATGGAGATACGCCTGAAGATACTAATGATGACGTGAATACATTGGAACATGACGTACTTTCCACTAAAGCGGAATTGGAGATATATGATGAAAGTAGCAATGaagattcttttaaaaaatctaatgaagAATTTGACGTAGTTGCCGATAAAGACGAATTGGTGGTATATTATGAAGTTCCTTTAGCCAAATGTGGAAATGATAAGAAAACGTCAAATACTGATGCAGAAAAGGCTAAATCCCAAGATAAAATTAATAGTCCTAATCATGGAGCTGATAGTGATGACAATAAAAGTGACAGTAAATTGGAATGTACCAAATGCtacaaagtatataaatttGCACACGGACTTCGTGAACATATGGCCAAACATACCGAACAAATTATCTATCAGTGTCAACATTGcccaacaaaatttacaatgtatAGAAATATTAGTCGTCATATGAAAACTCGTCATCCGAAAGAATACGCCGAGTCTTGTTCAAACaaatctaaaaacataaaaacccgGTCAAGAacgaaaaagcaattaaatttagAAGAGCATGATTTATACAATTTAGACTATAAAACAAAAGATGAAAATTCTCAAGATGCCTATTTACTTACAGGGCAAgaacattttgtaaatataaatgaattttctcAAAGCTCCCAACTAACTTTCGGCCAAGAAACTAATTCAGATACTGAACCTCTTGAGAAAAATTCTCAAGCTATGGAAATTTTAGAGGATCCTATTGATGACTCTACGACTATGGATGAATTTGCTCAAATTACCCAACTATCTGATGACACAGATAGCGATGAGCTACCTTGTAGCGATGATAGTGATGATGATATTCAATCTGTTGATGAAGATATTGATAAAGAAACTATTGACGAACAACAACATAATGTTGgcgaaagtaaatttaaatgtcCCCATTGTCGTGCCAAATTTACATGGGAGGGAAGCCTTAGTAGTCATATTAAACGAGTTCATCCTGAAGCATTACAGGGATATGATCCAAACCAAAAAACAAGTGAAGAAAATCCAGCATTTGCAAAAACTCACAATAAGGAATACAAATATCTAGAAAAAATGCAGGAACGTGATGCTTTGATAGCTAAATGGTTACCAGAATTAGAATGtattatatgtaaaaatacatttacatCATTCCCCTTTTTGAATCAACATTTTAAAGACAATCATCCCAATGAAAGATTAAATGTCATATGCTGCGGAAATAAATATCCCTCCCGTTCCAATTTATACGAACACATACAGCTTCATCTAGATCCAAATGCTTTTAAATGTGAATTATGTAAAAGATGTTTTAAGGATAGTGTAACTTTGAAAAAACATAAACGGCGATTACATACCGAACATGCAGAACGTCCATTTGAATGTGaagtttgtgaaaaaaaatttaaaaccaatcgTGAATTAAAAACCCACTCAGACCTTCATAATGCAGAAAGAAATCATGTTTGCAAAATGTGCGACAAGGCGTTTCCAAGCAAACAACGGCTTAAGAAACATGAACACAACGCTCATCAGAAAAATCTGTGTGAACATTGTGGCCAATCTTTTCATAACATTTCAAATTACCGAATTCATCTCTTTAAACATACTGGTGTGGAACCACCAAAATATCCCTGCAACATTTGTGGCGCCCAATTAAAGTCACGTGTAACTTTATATCTTCACAAAAAAGCGATTCATCATGATCATTCGACTATTTACGTATGCAGTGAATGTGGTAAAGTTGCTGCCACTAAAAAAGCTTTGAAAGTGCATAAAAGAAATGTTCACGGACCTGAACTTAAACGTAAATTCAAATGTTCTCAGTGCGATAAAGCTTTCAGAGCTCCTCAATTATTGCGTGAACATGAAGCAGGACATGCTGGCGAGCCGCTTTATGCGTGCCCGCATTGCCCGACAAAAATCAAAGCATATCCTAATTTTCAgcgtcatttaaaaaattttcatcccAAAGAATATGAGGtttctaaatttaaagcaaaagatCGGAGAAGcgcaccaaaaattgatttaaatttagtcGTACAAGAGattgttatttaa
- Protein Sequence
- MSPTILCRLCRCYQNNFIKLFEENGQSNEIYEITVKYFDPPMLLASEQGNHLTAICLECWHHINEFYEFQQLIYKAHEKLESIEIVHLDEKIEHEENNEDNNGDTPEDTNDDVNTLEHDVLSTKAELEIYDESSNEDSFKKSNEEFDVVADKDELVVYYEVPLAKCGNDKKTSNTDAEKAKSQDKINSPNHGADSDDNKSDSKLECTKCYKVYKFAHGLREHMAKHTEQIIYQCQHCPTKFTMYRNISRHMKTRHPKEYAESCSNKSKNIKTRSRTKKQLNLEEHDLYNLDYKTKDENSQDAYLLTGQEHFVNINEFSQSSQLTFGQETNSDTEPLEKNSQAMEILEDPIDDSTTMDEFAQITQLSDDTDSDELPCSDDSDDDIQSVDEDIDKETIDEQQHNVGESKFKCPHCRAKFTWEGSLSSHIKRVHPEALQGYDPNQKTSEENPAFAKTHNKEYKYLEKMQERDALIAKWLPELECIICKNTFTSFPFLNQHFKDNHPNERLNVICCGNKYPSRSNLYEHIQLHLDPNAFKCELCKRCFKDSVTLKKHKRRLHTEHAERPFECEVCEKKFKTNRELKTHSDLHNAERNHVCKMCDKAFPSKQRLKKHEHNAHQKNLCEHCGQSFHNISNYRIHLFKHTGVEPPKYPCNICGAQLKSRVTLYLHKKAIHHDHSTIYVCSECGKVAATKKALKVHKRNVHGPELKRKFKCSQCDKAFRAPQLLREHEAGHAGEPLYACPHCPTKIKAYPNFQRHLKNFHPKEYEVSKFKAKDRRSAPKIDLNLVVQEIVI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -