Basic Information

Gene Symbol
salm
Assembly
GCA_951802225.1
Location
OX637669.1:4185566-4202721[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.014 0.96 10.5 1.7 1 23 112 134 111 134 0.92
2 14 0.0012 0.082 13.9 1.1 1 23 353 375 353 375 0.99
3 14 1.7e-05 0.0012 19.7 0.7 1 23 381 404 381 404 0.97
4 14 0.0077 0.54 11.3 1.0 3 23 411 432 409 432 0.95
5 14 5e-05 0.0035 18.2 2.6 2 23 622 643 621 643 0.97
6 14 9.7e-07 6.8e-05 23.6 2.9 1 23 649 671 649 671 0.99
7 14 2.7 1.9e+02 3.3 3.4 1 21 738 758 738 760 0.91
8 14 0.0006 0.042 14.8 1.8 1 23 795 817 795 817 0.96
9 14 7.3e-06 0.00051 20.8 0.8 1 23 823 845 823 845 0.98
10 14 0.049 3.4 8.8 6.1 1 23 854 876 854 876 0.98
11 14 0.0005 0.035 15.0 0.7 3 23 924 944 923 944 0.97
12 14 0.0022 0.15 13.0 1.9 1 23 958 980 958 980 0.96
13 14 3.1e-06 0.00022 22.0 0.7 1 23 986 1008 986 1008 0.98
14 14 7.5e-05 0.0053 17.6 5.2 1 23 1014 1037 1014 1037 0.98

Sequence Information

Coding Sequence
atggaaaccGAAGTCGACCCTCTAGATCCAAACTACGTTCCCAACTACGAACAGCCTGTCCACCAGGGGGACTATCAGCAGCTGGAACCGTTTGTCCAAATTAAAACGGAACCCTGCAACGAAGATGGGACAGAGATCTTTAGAGACTTTTACCAGATTGTTGAGGATTTACCGCCTGTCTCCGTTCCCGCTGCCACTGAGGAGAGGAAAGCTGACGAGGTTGTTGAGGAACCAGACCCACCAAGCCCAGTACGTAAGCGCAAGCGTCGAACAAAGCTCCAAATGAGCACTATAAGTAAAGAAGCGGAGGATATCCAGAATGCTATACCATTCTACTGCTGTGCGGTCTGCGATGCAAAGTATAACAGACTCGAGAAGTTGCAGAAACATGTTACTGAGCATAAAGGGAGGCTCACCAGTTGGGATCTGAAGGTAAGAAACCAAAAAATGCGCAAAACCCTCAAGAAGGCACAGaagaaattgaaaaagataaaaatagaaaagttAGACGATATAGAAATTAAAGAGGAGAAGATTGACCCGGAATACGAGAAAAACGATCCAACTTCGAACTATGGCGTTTCAATGGGGAATAATGACGTCACAATGGGGAATAATGACGTCAAAAACGGGAATAATGAATCAAATATAGCTGCAGATATAAATATACCAAGTGAAGCAAGTATACCGACTGTAAGAAATGAAAACAACGATTTATGCAATGAATTAGTTAATGAAATTGGGAATATAATTATGGGAAAATTGGTTAGTAATGTTGAAGATGCTACTCAGTTTAGCAGAAATATAGGAACTGATAAAGTGACAGAAGATTCTGGAGTTGTTAATAGTGTTAATGATAAAGTGTCTGATGTTAATAAAGTTATCGGTGAGAAAGTTATCAGTGGAAAAGTTATTGGTGAGAAACTTGGTGCAGTTAATGAGAATGGTGAGAAATCAGGTGTTGATGTTAGCGGAGATTTAAATGGAGTGGTGAAAAGTGAGAAAAGTGAGCGTAATGGGCAAACGGAGGAGGAAATAGACAACTTGGAACGGATATTCAAATGTGGTGGCTGTAGCAAGCAGTTCTCGCTGGGTTACTATCTGAAGCTGCATGTGCGGTCGCATAcaggCGAAAAGCCCTACATATGTCAAGAATGTGGTCAGACGTTTATAACGGCGTCGAAACTTGGACGACACCGGAAGAGGACGCACTTGTGTCTCAGAGTGATATGTCGTATATGCAGACGATCTTATACAAGACTGGAGTTTCTTATGAAGCACTTCAATAAGGTCCACGCTGAAGATAAGATTGAGGGCGAGCCCTACGATTACAACGCGATCCTCCCCTACCTAAAGGATTTGGAGGAGGAGTTGCAACAAAAGAAGGAGGAGGAGGAGAAACGGAAGTTGGAGGAGTCGAGGCGGTTCGGGGAGGAGTTTATGGATGTACTTCAAGAGTTTAAACCTAAGGATGAGgaTATGATACCGGAACTAAAAACCGAGATAGAGGTGAAACATGAACCTGGTATAAAGGCGGAATCGGATTATAAAATTGAAGGGGACTTCGTGTCGGTCGGCGTGGAGGAGGTCGGGGAGAAAGGGGGAGCTTTGGAAAGTTCGGGGGATTTGGGGGATTTGGGGGTCTCGGGGGATTTGGGGGATGATGGCGATAATGGCGACCACGGTGGGGATTTTGACGATTTCGCTGTCAGCCCTAAGCATGAATCTTCCGATGACGAAGATTACTTCCCAGACAACACTTGGCTACCAGTGAACGAAGAGCCGGCCCCAATAAAACCCAAAAAACCCTCAAAACCCCCAAAGTCGAACAAAACACGCCACAAGGAAGATACATCGTTaactacgtgcaaaatttgcCACAAAAATGTTTCGAGTTCGACGTATTTGAGAATTCATATGCGGATACATACGAAGGAAAAACCGTATAAGTGTCACCTGTGTGAAAAGACCTTTATAACGGCCTCGAAGCTCACTCGGCATGTGATGACGCATTCGAATTGGGATGATGATGACGTTGTTAAAAAAGAAGTCGATGAAAAGACAGAAGGAAACGAAGATGaaaacaaCCCCGAAGCGAAGCCAAAGAAGGTAAAGAAACGGCGTCGTCGACGTAAGAACCAGTTACCTGACGGAGTTCTAGTGAAAAAGGAAAAAACCGATGGTGTACATAAGCAGCCGAAGCCGCGGCCGCACGCGTGTGAATATTGCAGGAAGAGGTTCCTTTATATTGAAGCTTTGCAAGTGCACAGGAGGTGTCATGCAGGAGAGTCAGCAGAGCTGCACTGTGGCTTCTGCCTAACCCCGTGCGCGGACATCGCCTCGCTGAGGGAGCACGAGGCGCGCCACGCCCCGCCGCGACCCTACCTGTGCACTCTGTGCGGCCGGACTTATACCAAGAAGGAAACTATgATATACCACCGTCGCATGCACGAGGCAGACAACAAGTACCAGTGCGACGTCTGCCCCAAGTCCTTCAACGCGAAGAACAAACTCCAGCGACACCTGCTGTCGCACCGCGCGGGCAAGTCCGCGGTCCGGTACGAGTGCCCCGTGTGCGCGCACTGCTTCCACACCCGCTACCATGTGGAGATGCATCTGGCCACGCACGAGAAGGAGGGAGTAATCCAAGAAGAGAACCGAGGCCAGGTGCTAGCAATGGTGTTGCAGAACGCCCGAAGGATACCGCTCGAAACGGACACTCCAGCCGATTCCAAGCAGCTAGAATGGGGGGACGAACGTTCTAGAATATGCAACATCTGCGGGGAAatttttatgcatttttaCCTCTTAGAACAGCATTTAAAATCCCACGGCAGCAGCATATGCAAAGGGAGAGAGGAGGAGAAGAAATACATATGCCAAGTTTGCAATAAAGGGTTCAAACTAAGCTATTACTTAAAATTGCACAATTTTACACACACGAAAGAAAAACCTTTTATTTGCCAACAGTGTGGAAAAGGTTTTATTACTAGGGGCAAGCTGAAAAGGCATTTGGAGACGCACGCAGGTTTAAAGAAGTACCAGTGCCACATTTGCTGCAAGTTTTTCACGAGGCCCAGTTATTTGAGGATCCATGTTAGAACGATTCACGGTACGCAGgattataatttcaaaatggATAGTTATTATAGTGAGTCCTTGGATGATATTTCTATGACGCACGATagtgtttaa
Protein Sequence
METEVDPLDPNYVPNYEQPVHQGDYQQLEPFVQIKTEPCNEDGTEIFRDFYQIVEDLPPVSVPAATEERKADEVVEEPDPPSPVRKRKRRTKLQMSTISKEAEDIQNAIPFYCCAVCDAKYNRLEKLQKHVTEHKGRLTSWDLKVRNQKMRKTLKKAQKKLKKIKIEKLDDIEIKEEKIDPEYEKNDPTSNYGVSMGNNDVTMGNNDVKNGNNESNIAADINIPSEASIPTVRNENNDLCNELVNEIGNIIMGKLVSNVEDATQFSRNIGTDKVTEDSGVVNSVNDKVSDVNKVIGEKVISGKVIGEKLGAVNENGEKSGVDVSGDLNGVVKSEKSERNGQTEEEIDNLERIFKCGGCSKQFSLGYYLKLHVRSHTGEKPYICQECGQTFITASKLGRHRKRTHLCLRVICRICRRSYTRLEFLMKHFNKVHAEDKIEGEPYDYNAILPYLKDLEEELQQKKEEEEKRKLEESRRFGEEFMDVLQEFKPKDEDMIPELKTEIEVKHEPGIKAESDYKIEGDFVSVGVEEVGEKGGALESSGDLGDLGVSGDLGDDGDNGDHGGDFDDFAVSPKHESSDDEDYFPDNTWLPVNEEPAPIKPKKPSKPPKSNKTRHKEDTSLTTCKICHKNVSSSTYLRIHMRIHTKEKPYKCHLCEKTFITASKLTRHVMTHSNWDDDDVVKKEVDEKTEGNEDENNPEAKPKKVKKRRRRRKNQLPDGVLVKKEKTDGVHKQPKPRPHACEYCRKRFLYIEALQVHRRCHAGESAELHCGFCLTPCADIASLREHEARHAPPRPYLCTLCGRTYTKKETMIYHRRMHEADNKYQCDVCPKSFNAKNKLQRHLLSHRAGKSAVRYECPVCAHCFHTRYHVEMHLATHEKEGVIQEENRGQVLAMVLQNARRIPLETDTPADSKQLEWGDERSRICNICGEIFMHFYLLEQHLKSHGSSICKGREEEKKYICQVCNKGFKLSYYLKLHNFTHTKEKPFICQQCGKGFITRGKLKRHLETHAGLKKYQCHICCKFFTRPSYLRIHVRTIHGTQDYNFKMDSYYSESLDDISMTHDSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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