Basic Information

Gene Symbol
-
Assembly
GCA_951802225.1
Location
OX637669.1:633460-637430[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 23 0.015 1 10.4 0.2 3 23 27 48 25 48 0.94
2 23 0.44 30 5.8 0.1 1 21 99 119 99 120 0.93
3 23 0.67 47 5.2 0.4 1 20 128 147 128 149 0.92
4 23 0.2 14 6.9 2.0 1 23 156 179 156 179 0.96
5 23 0.0012 0.085 13.8 0.2 2 23 186 208 185 208 0.96
6 23 6.5e-05 0.0045 17.8 0.2 2 23 213 234 213 234 0.95
7 23 0.0087 0.61 11.2 0.1 2 23 330 352 329 352 0.94
8 23 0.00015 0.011 16.7 1.3 1 23 400 423 400 423 0.96
9 23 0.99 69 4.7 1.6 1 21 428 448 428 449 0.94
10 23 0.31 21 6.3 0.1 1 23 456 479 456 479 0.92
11 23 4.1e-05 0.0029 18.5 0.4 1 23 486 509 486 509 0.97
12 23 1.9e-05 0.0013 19.6 0.1 2 23 514 535 514 535 0.97
13 23 0.00056 0.039 14.9 1.7 1 19 541 559 541 563 0.96
14 23 0.064 4.5 8.4 0.7 1 14 569 582 569 585 0.89
15 23 0.00075 0.052 14.5 0.2 2 23 645 667 645 667 0.94
16 23 0.095 6.7 7.9 0.4 2 23 693 715 692 715 0.94
17 23 0.00053 0.037 15.0 0.6 1 21 763 783 763 784 0.95
18 23 0.21 15 6.8 0.9 1 20 791 810 791 812 0.91
19 23 0.0028 0.19 12.7 0.1 1 23 819 842 819 842 0.95
20 23 0.019 1.4 10.0 2.1 1 23 849 872 849 872 0.97
21 23 0.004 0.28 12.2 4.8 1 23 877 899 877 899 0.98
22 23 0.003 0.21 12.6 0.3 1 19 905 923 905 927 0.96
23 23 1.4e-05 0.001 19.9 4.6 1 23 933 955 933 956 0.96

Sequence Information

Coding Sequence
ATGGATGTGCGTGTTGCTTTGCGGCACATTAGTGCAGTACCGACGAGTTTCTTAAAACTAGACTGTACGGAACTGGCGTGTCGCTCTTGCTCGAAGCCCTTCAAAAGACTGTCGGACATTGTTGACCACCTGCGGGAGGTGCACCGAGCGAAACTCAATCTGGACGAGCCGCTCCAAGCGTTCCCCTATTTGATGGACAGTGGAGGGCTTCGATGCGGCATATGCGACAGTCGCCAGGCCACCATCACTAAGCTAGGCCAACATTTCTGGACCCACTTTGTGAAACGGTTCAGGCACACTTGCGAAAGTTGCGGCAAGGGCATCCAGTCGTCGCACGATATGGCAGCGCATGCACGCATCTGCTCCAGGACGGAAAAGAAGTTCTTCTGCCCGCAATGCAATGATTCTTTCGGTTCGCGGAAAGAGAAGCGTGCTCACCTCTTGAATTCCAAGCGCTGTCAGAGACATCGCTGTCAAGTGTGCGGAGATCGGTTCACTACAGATTTTCAGAAAGTGAAACACTTAAAAGTGGTGCATGATTTTGTCAAAGAAATACCCTGCAACGAATGCGATTTGGTATTTGATACTAGACCAAAGTATTTGGCGCACTACCGTAAGACTCACCAGCACGCGAACGTGTGCCCTCACTGCGGCAAAGTGTTTGCGTACAAACTGTCCTTGCAGGAACACGTAGTAGTCCATACTCGGGAGAAATCGTTTGAATGCGATGactatttctttgttttagaGTATACGGGAAATGCAAGCATCACCCGTTGGAACGCCGAGATCATAATAAAATTCACAACGGCATATCCTTTCCGGAACCCGAAGAACCTTATACTATGTGTGTTTTGCGCTACTGAATTCCATAAAGGGGTTGAGTTCAGAGAGCATATGAAGGAGAAGCATAAACAGATGAATATGAAGGTTGGCCTTAAGCACGTCTCTAGGGAAAACATGCTGAAACTCGACTGCACGGAGCTCACGTGCCGTATTTGCGAAAAGCCCTTTAAAAAATTGGACGAAGTTGCTCTTCATCTTAAGCTTGAACACCGCGCCAGGCTTCGATTGGATACTGGTCTAGAAATGTTCCCTGTCATCCTGGACGTGGATAAGATATGTTGCGGCATATGCGACTGCAAGCAGGGCGGCCTTAGGCAGCTCAGTATGCACATGACTTCGCACTTCCCGCGCTTCTCGTGCGAACACTGCGGCAAAATCTTCATGAGCGAGATTAATTTGAGGATTCACAATCGCAACAGTCACACAGAGCAGAAACACACTTGCTTGAAGTGCCATTCAGTGTTCGATACGTTAGAAGAGAGGCGCAGCCACCTTAAAGACTCGCAGCGTTGTCGACGTTACGCCTGCGACTTTTGCGTCGAACGATTCATGACCCCGATAGAAAAGGAGAGGCATATGGTCGAGGTTCACGAAAAGCCAGCGAGAATTTTTCCCTGTCCCGAATGCAACGAGGTTTTTGATAGGTCACATAAACTTGGGACGCATTATCGTGTAGCCCACGGCGCAGGTCGCGTTTGCCCAAACTGCGGGAAGACGTTTGACTCCCAGGGGAAGCTTGATGATCACATGGTGACTCACACTAAGGCGAAGCCTTACAGTTGTGAGCATTGCTCCAAAGGTTTTGGCACCAAAAGGAATCTGCGGCAGCACTCGTGGATTCATCTAGAAGAAAAGAGGTTCTCGTGTGAAATGTGCAACAAGAAGTTCAATCAGAAAGTCAGTTGGCACTTCGGCAGACCTTACACAATATGCCAAATAACAAGGGATATTGGCACCAAGAATGACCGAGAATATTTCTTTGTTCTAGACGTGAGCGTGAGGGAAATAAATGTGGCGCGATGGAATGCTGAGATCATTGTGAAATTTGCCACTGCCTTCCCGTTCCGGCTGCCTGGCGACAAGCCCGTCTGCCTCTACTGCAACAATAGTTACAGTGACCCGGCCGAGTTCCGCCGGCACATGGAACAGGAGCATACTACCTTTAGTAGGCGCCACGTATTCGCTCACGTCTCCCCCGAGAACTTTCTAAAGCTGGACTGCACAGAGCTCTCTTGTCGGATTTGCAAACAAAAATACGCCAGGCTCGATCAGATTTCTGAACATTTGAAACTGGAGCACCGAGCTAAGCTGAAGCTTGAAAATGGGCTCGACCTCCTTCCTTACGTCATAGGGCCGGGTAGGATGGCTTGCGGGATATGCGACGTTAACCAGCCAGGGTTCAGACAGCTCGGGAGACACCTAGCCTCTCACTTCCAAAAGTTCACGTGCGAATCCTGTGGCAAATCTTATATCAATCTGACTTCTCTCCGCCAGCACACGCAGTTCTGCAACAAAATGAAGCGCTACCACTGCTGGAAGTGTCGCAAGAATTTCGAAACGCCAGAGAAGAGGCGCGAGCATGTCGAGCAAACGAAATTCTGCTGGCGCTACACCTGTGATCTATGCAGCGAGCGCTTCATAAAGTGGTCGTCGCGTGAAGACCACATGATTGCCGTGCACAACCGCCCGACAAGGACATACAACTGCGCGGAATGCGGAGAGGTGTTCGACTGTCAACGCGGCTATCGGCGCCATTTTAGAACAATGCACAGCGGCAACGAATACCGCTGCAAATACTGCGGCAAGGGATGCGAGTCTAAGAAATGCTTGGACGAGCATCTAGTGACGCACACGAAGGAGAAGCATTACACTTGTGAAGTCTGCCTCAAAGGGTTTGGGACTAAAAAGAATCTGATCCAGCATTCGTGGATTCATAATGATTATAAGAGATTCGAATGCAAGATGTGCGATAAGAAGTTTAATCAGAAAGTTAGTTGGAAGACGCACATGAAGTCGCATCATCCGGAGTTAGTAGACTTTTAA
Protein Sequence
MDVRVALRHISAVPTSFLKLDCTELACRSCSKPFKRLSDIVDHLREVHRAKLNLDEPLQAFPYLMDSGGLRCGICDSRQATITKLGQHFWTHFVKRFRHTCESCGKGIQSSHDMAAHARICSRTEKKFFCPQCNDSFGSRKEKRAHLLNSKRCQRHRCQVCGDRFTTDFQKVKHLKVVHDFVKEIPCNECDLVFDTRPKYLAHYRKTHQHANVCPHCGKVFAYKLSLQEHVVVHTREKSFECDDYFFVLEYTGNASITRWNAEIIIKFTTAYPFRNPKNLILCVFCATEFHKGVEFREHMKEKHKQMNMKVGLKHVSRENMLKLDCTELTCRICEKPFKKLDEVALHLKLEHRARLRLDTGLEMFPVILDVDKICCGICDCKQGGLRQLSMHMTSHFPRFSCEHCGKIFMSEINLRIHNRNSHTEQKHTCLKCHSVFDTLEERRSHLKDSQRCRRYACDFCVERFMTPIEKERHMVEVHEKPARIFPCPECNEVFDRSHKLGTHYRVAHGAGRVCPNCGKTFDSQGKLDDHMVTHTKAKPYSCEHCSKGFGTKRNLRQHSWIHLEEKRFSCEMCNKKFNQKVSWHFGRPYTICQITRDIGTKNDREYFFVLDVSVREINVARWNAEIIVKFATAFPFRLPGDKPVCLYCNNSYSDPAEFRRHMEQEHTTFSRRHVFAHVSPENFLKLDCTELSCRICKQKYARLDQISEHLKLEHRAKLKLENGLDLLPYVIGPGRMACGICDVNQPGFRQLGRHLASHFQKFTCESCGKSYINLTSLRQHTQFCNKMKRYHCWKCRKNFETPEKRREHVEQTKFCWRYTCDLCSERFIKWSSREDHMIAVHNRPTRTYNCAECGEVFDCQRGYRRHFRTMHSGNEYRCKYCGKGCESKKCLDEHLVTHTKEKHYTCEVCLKGFGTKKNLIQHSWIHNDYKRFECKMCDKKFNQKVSWKTHMKSHHPELVDF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-