Eher005060.1
Basic Information
- Insect
- Euschistus heros
- Gene Symbol
- lola
- Assembly
- GCA_003667255.1
- Location
- RCWM01000006.1:7348805-7357645[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 9 0.67 4.3e+02 4.4 0.2 3 19 65 81 63 84 0.91 2 9 1.1e-05 0.0068 19.5 0.0 1 23 91 113 91 113 0.98 3 9 1.1e-05 0.0071 19.4 3.5 2 21 118 137 117 138 0.94 4 9 0.0029 1.8 11.8 1.4 2 23 147 169 146 169 0.91 5 9 0.00014 0.087 16.0 1.8 1 23 191 214 191 214 0.95 6 9 0.0032 2 11.7 3.2 1 21 227 247 227 248 0.93 7 9 0.024 15 8.9 8.3 1 23 256 278 256 278 0.98 8 9 3.9e-05 0.025 17.7 1.9 1 21 296 316 296 317 0.95 9 9 2.1e-06 0.0013 21.7 4.1 1 23 325 348 325 348 0.97
Sequence Information
- Coding Sequence
- atgtttttatttaccCCTTATTTTCTCATCTCTCCTGCTTGTGAGGTGGAATTGGGTGCTCTAAACCCTTTGACTGTGCTTGTCCTCGAAGAAGAAGGAGTTCTTAAGGAAGAAGGAAATGAGGAAGAAGTTGTTGAGGACGATGATAATAGCAATACAGAAGTTGAGcatgaggttcagtcaatgaTAATCTGCCATTGTTGTGGTGCTGAATTTGCCGAGGAAACTGAATTGGAAAAGCACAGTTCTATTTGTTCATCAAACTTGGTATACGAATGTGCTATTTGTGGTGCTTCATTTTCATCAGAACTTGGGCTGAGGAATCATGTCCGAGTTCATTCAGATGGGTGCACCTGTGAAAAATGTGGAAAACATTTCAGGAAAGCAGTCAACTTGAAAACTCATCAGAGGGAGGAGTGTGGTCAGGAACCTTCTCTGGAGTGCCCCCTGTGTGATGAGCGGTTTCACTTCAAGGCCCAGCTTAATGGCCACCTCATTGACTGTCACAGCGAGGCAAAGCTTGTGTTTCCGCAGCAGGAATCAGTTCAATCGCAGTCACCTGATAAACAATTTCATTGCGAACTGTGTCCTAGATCATTCTCTAGGGTTGGCTCACTCAACTACCATGTTTCAAGAAAACATTCAGGAGACATCCAGAGGAGTGCTGAGGAGTTCCCTTACCTCTGCTTCACATGTGGTAACAGGTATAAGTCCAGCACCCAGCTCTGCAGGCATCGCAggTGGGAGTGCGAAAAGGAACCTATGTTTAAATGTCAGCTTTGTGCTAATAAGTTTCACCATAGACATGGATTGAAACAGCATATGAGATTGCACATTGCGAAGAAGGGCCAACCTCCTGGGAAGGGGTCCTTGGCATCTGCACAATTCTGTTGTGAGAAATGTGGCCGTGGTTACAAACTCAAATCCAGCCTAAACAATCATATGAAATGGGAGTGTGGCAAGGATCCCTTTTTTCCTTGTTCTGTCTGCCACGTCCGATTCTCCCATAAGGGTAATCTGAAGAAGCACATCCTTACAAAACATGTCAAAAAGCAGCCTTCTGTTGTTTCCAAGAAAGAAGAATAG
- Protein Sequence
- MFLFTPYFLISPACEVELGALNPLTVLVLEEEGVLKEEGNEEEVVEDDDNSNTEVEHEVQSMIICHCCGAEFAEETELEKHSSICSSNLVYECAICGASFSSELGLRNHVRVHSDGCTCEKCGKHFRKAVNLKTHQREECGQEPSLECPLCDERFHFKAQLNGHLIDCHSEAKLVFPQQESVQSQSPDKQFHCELCPRSFSRVGSLNYHVSRKHSGDIQRSAEEFPYLCFTCGNRYKSSTQLCRHRRWECEKEPMFKCQLCANKFHHRHGLKQHMRLHIAKKGQPPGKGSLASAQFCCEKCGRGYKLKSSLNNHMKWECGKDPFFPCSVCHVRFSHKGNLKKHILTKHVKKQPSVVSKKEE*
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_01298649;
- 90% Identity
- -
- 80% Identity
- -