Basic Information

Insect: Eurytoma californica
Gene Symbol: ZFHX3
Assembly: GCA_035586675.1
Location: JAXIUT010000026.1:12466-25850[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.11 14 7.4 0.2 2 23 206 228 205 228 0.94

2 14 0.0002 0.026 16.0 1.8 2 23 446 468 445 468 0.95

3 14 5.1e-05 0.0065 17.9 0.7 1 23 500 524 500 524 0.92

4 14 0.087 11 7.7 0.3 1 22 580 601 580 604 0.91

5 14 3.8 4.9e+02 2.6 0.1 1 23 869 893 869 893 0.88

6 14 3.6 4.7e+02 2.6 0.2 3 23 986 1007 984 1007 0.92

7 14 0.014 1.7 10.3 2.5 3 23 1028 1049 1027 1049 0.95

8 14 0.0014 0.19 13.3 1.7 2 23 1112 1134 1111 1134 0.96

9 14 0.0024 0.31 12.6 1.3 1 23 1151 1173 1151 1173 0.97

10 14 0.26 33 6.3 3.1 2 23 1180 1202 1179 1202 0.96

11 14 0.1 13 7.5 5.8 1 23 1291 1315 1291 1315 0.91

12 14 0.0059 0.76 11.4 0.6 1 22 1335 1356 1335 1359 0.89

13 14 0.0093 1.2 10.8 0.2 1 23 1397 1421 1397 1421 0.92

14 14 0.58 75 5.1 0.4 2 21 1652 1671 1652 1675 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.11	14	7.4	0.2	2	23	206	228	205	228	0.94
2	14	0.0002	0.026	16.0	1.8	2	23	446	468	445	468	0.95
3	14	5.1e-05	0.0065	17.9	0.7	1	23	500	524	500	524	0.92
4	14	0.087	11	7.7	0.3	1	22	580	601	580	604	0.91
5	14	3.8	4.9e+02	2.6	0.1	1	23	869	893	869	893	0.88
6	14	3.6	4.7e+02	2.6	0.2	3	23	986	1007	984	1007	0.92
7	14	0.014	1.7	10.3	2.5	3	23	1028	1049	1027	1049	0.95
8	14	0.0014	0.19	13.3	1.7	2	23	1112	1134	1111	1134	0.96
9	14	0.0024	0.31	12.6	1.3	1	23	1151	1173	1151	1173	0.97
10	14	0.26	33	6.3	3.1	2	23	1180	1202	1179	1202	0.96
11	14	0.1	13	7.5	5.8	1	23	1291	1315	1291	1315	0.91
12	14	0.0059	0.76	11.4	0.6	1	22	1335	1356	1335	1359	0.89
13	14	0.0093	1.2	10.8	0.2	1	23	1397	1421	1397	1421	0.92
14	14	0.58	75	5.1	0.4	2	21	1652	1671	1652	1675	0.89

Sequence Information

Coding Sequence: ATGAGCCCTGAAGAAGAGGGTAGCCGAGGGGGCGGGTCCCCACCGGCTACAGGGGCTGCTTTACATCAACCTCATTACCCACTCACTGCTAGTCCAGCTTCCGGTACAGAACCTTGTACTCGTGATACAATTTCAACTCCTATATCAGCAGCAGATACTACTACAAATGTGTCAGAATCCGCTATTTTAACAACTAATTTACAACATAACAGTCCAAGCCCGAGTCCTTCTGGTTGcgatgttgaaaaatttgatggtaaaattgtatataatccTGATGGATCAGCATACATTATTGAAGGTGAAAGTGAATTAAGTGATGATGATTCCTTACCAGACGGTTGCATCGTTGATGGACGAggaatttcaatttctcaTTCATTAGTATTTCCCCAAATTGCTAACGCTTATTATGTATCCAGACTTTATGCGCACCAAGCTTATCAACATCACCAACAACAAAGATCGTCAATTATTCCATCAAATCCTGAACTTCCCGTTATGCATAGCTATCGTGTGATTAGTTATAGAAGTTCCGATGGAAGTGCGCAGTTGTCACGTTCTACATCGACATCATCGATTTCTGCAACTTCAGTACCAGTGAAACCAATTTTAATGTGCTTTATTTGCAAACTTAGCTTTGGTTATGCAAAAAGTTTTGTGGCTCATGCTCAAAGTGAACATGAGTTAACATTAATGGATGACGAAAGACAAATACTATCCCATGCCACTGCTTCAGCTATAATACAGGTTGTAGGAAAAAATAAGCAACCAATCGTAAGTCTTCTTGAGCCTGTTTCAACAGCACAATGTCCGCAAGACTCTTTAGAACAAATTCCAGGGCAAGGTTCACACAATGGAGATGAAGAAATTAGTCAGGAGTCAtcgaataaaatgaatacacaaataaatacatcaaacactgttgaaaatttacataattttcaaaacaaagcAAATGTAAATACTTCCTTAATGACTTCTTCaacaaatcaaaatcaaaatgttcTGTATAATTATCAACATCATCAGTGGATAAATACTCAAGTTAGTTCTTCTTCATGGTCTAAAATAACTGAATCATCTCCAAACAGCCTTTCTTCATCAATAACTTCAACACCGTTAAAATCTTCGCAATCatcgttttcaaatttatctcAACCACccccaaattttttaactggtACTACTATTGGTGTATGCCCAGAACATTTACAAGGTAGACCGAGTGGTATAGAGTGTTCAAAATGTGAGTTAATATTAGCAACTAACAGATTATCAGCAGCAAGTGGATCATTGGCAGGTATACACAGTAGAAATTCTTGTAAGACATTGAAGTGTCCTAAGTGTAATTGGCATTACAAATATCAAGAAACCTTGGAGATTCACATGAAAGAGAAACATCCCGATAGCGAAACATCATGCATTTATTGCATCGCTGGACAACCGCATCCTCGACTTGCAAGGGGTGAAACCTATACATGTGGATATAAGCCTTACAGATGCGAAGTTTGCAATTATTCAACAACTACAAAAGGCAATTTAAGTATTCACATGCAAAGTGATAAGCATCTAAACAATATGCAAGAACTGCAGCAAAGTGGTAGTAGCTCTAATGCAAATAACCCATCATCATCTCAAGATCAACCTGTTCCTACTCGAAGTCCTCTTCATCAACAAAATCATAGTCCCTTGTTAAGTGGACAATCATCTACTCAAGGAAAATCAAAGCCAACATTTCGTTGTGATGCTTGTAATTATGAGACAAATGTTGCTCGAAATCTTAGAATACACATGACAAGTGAAAAACATACTCATCACATGCTAGTATtgcaacaaaatattaaacatataCAAACCTTATCTGCATTTCAAACTCATCATCAACAAGTACAGCAAAATCAAATACAACATCAGCAACAACTTGAGCAATTTCTTCATTTAGGTAATTTAGATAAACCTCAACACGCTGAAGCTGCTTTGGCAGATATGGCATATAATCAAGCTCTTTTAATACAAATGATGACAGGAGGTCAGTTACCACCACATGTTCCTCCAGAAATGGTCGGAAACATCAGTGCATTAGCGAATATGGGAGGGGACATCGGTCTGTCTCCAGAAAGTATGGAACCGCCACCAGAACCGTCAGATCCCGATCCATGTCATCTTTACCAATGCTGCGTATGTAACAACTTTGCAACTGATTCAATCGAAGGTCTTGGAATTCATTTAACTTCCGACAGGACAAAATCGAGGGAAGGTGAAATACTCAGTAATGTGGCCggacattttatttgtaaactaTGTTcctataaaactaatttaaaagcaaattttcaaCTTCATTGTAAAACGGATAAGCATTTACAAAGACTGCAACATGTAAATCATGTAAAGGAAGGAGGATCTCGCAATGAATGGAAACTAAAGTACCTTGCGTCACCGACAAGTACAGCACAAATACGTTGCCATGCTTGCGATTACTATACTAATAGTGTTCATAAATTAGCTCTTCACGCAGCTACACCTAGGCATGAGGCTGCAGCCCTTTTACTACGACACTTGCTTGAAGCAAGTAATAGTATATCATCTACTTCGAAACTATATCTTTGTGCACTTTGTGGGTTTAGTGCAAAAAATAGATTACCCTTACTTCAACATGTGAGATCTATTCGACATCTACATATGGAACAGTTACATCAACTACAAAGAAGAACGGGAATATCTGCCAGCGAAATTCCTCATACAGATATTGGAGATGTTTTTCAAGTATTATCGGACCCAAATGGCAGTACTACAAACTTGAAGTCtaaatcatctgatttatcaccacaaacaaaatttaaagaagattTACATATTGAGACTCAAGAGGGTGAGAAAAGATATGAGGCAAAGATAAAGCAAGAAATTGAACAGGAACAGGAGCATGATAACGACGTTGAAGATATTAATTGTTCATACTGTTCTTTTCAACCTTCAACAATAGAAGAACTGCGaaatcatttacaaatttctCATGCACATGATAATGATGAAAGAATCGATAATTCGAGAGAGGAAACTAATATAGAGTTATTATGTCCCCTGTGCCAAGATTGTTTTAAACATCGATCTGCACTTGAAAAACACGTTATGCAAATTCATTCAGTTAATGCAGATGGTTTACAAAGGTTGTTGCTTCTGGTAGATCAAAGTCATTGGTTAAACAGTAATCCTCGAAGTGTACATGCCGCTATTCCCTGTCCAAGATCAcctaacattttattaaaaaaaaatcaggatGATGAAAGTACAGAACAAATGGGTAGCGATGATGGCGAAGAAACCactaaatgtaatatttgtcCAAGGATGTGTCGTTCAGTAGAAGATCTTCAACAACATTACAGAGAGTCACATTCTTCATCTATACCAAGTTTGGCTGTAagtgagaaacatgtatataaatatagatgtGGCCAATGCAGTTTAGCTTTTAAAACATTGGATAAACTTCAGCAGCATTCTCAATACCATGCTATAAGGGATGCAACTAAGTGCGCTATTTGCTGTCGGTCTTTCCGGTCAGTTCAGGCTCTTCACAAACATCTAGAAACAGCTCATACTGAATTACAAGAAGACGAATTAACAcagtataaacaaaatttaataacatctCACCATCTTATACAAGCTTTAACTGAAGAATCTTTTCGAAGACAGGGAGTATTGAGCAGTGAGCAGTTAGTCGATGAGGATGGAAAAGTTGAAGATGATGAAAATGATTTAGGAGATTTATCTCCTTTACACAAAGAACAACGATTGCTTGAAGACTATTTGAACAGTCAATCTATAGCTGAAGATTCTTATAATGACCCTGGACGGAAATTTAAATGTCATCGATGTAAGGTTGCTTTTACTAGACAATGCTATCTTACTGGtcacaataaaactttattacatCGCAAAGGTGAAAAAATGCCTTATccaatggaaaaatatttggatCCAAATAGACCATACAAATGTGATGTTTGCAAGGAGAGCTTTACtcagaaaaatatacttcttGTTCATTACAATAGTGTGAGTCATTTACACAAACTGAAAAGAGCTATGCAAGAGCAAGGAAACAATAATACACTAGCATCCCCCTTGAGCCCAACAAATTTAAGTGACAGTCAACAGGATTTCGACAAGAAACCTTATAAATGTAACATATGTCAAGTTGCTTACTCACAAGGTAGTACCTTAGATATTCATAAAAGAAGTGTTCTCCATCAAACGCGAGCTAGCAAATATCATGAATCAGCCACATCATCTTCGGCAAACAGTGCTCCGATTACTACTACACCTACGTCGTTTCAATCACATGATAATGTCTatgataataaagaaaaagacgaATTATgcgataataaagaaaatataagcAAAACACCCGAAGCAACTTCGACAACTCCTACTACTACTCCCGCATTGAGTAACACACCAGTATCAAGTACAGACTCAACAACTTCAACCGCTCACAGCAATATTTCACCAACTCTTATGCAACAACAACATCAACAAGCTCAATTAACTTTAGCTCAACATATGTCTGAAATGCAGGCTGCATTCAATGTTATGGCAGCATCACAATTGCAACAATTTCATCAGTATCCAAGTTTAATGATGAGCATGATGGGTCTTCCCTTAGGTCTGAATATGCCAGCTCTTGCAGCTATGAACCTTCAACCACCATTAGTACCAGTAATGTTACCGCCTCCGACATTTGATGGAAGTAATAACAGTTATTCATCTATTATTTCAACACAATCagatttaattacaaaacagCATCTAGCTTTACAACAGCAACAAGTTGCAGTTTGGTTTCAGAATGCAcgtgcaaaagaaaaaaaagccagATTAGCCGCAGGACTATCAGCAGATGGAGTAGTAATCCATCGAGGCTTAACTGGTCCtgaagaatgtaaattatgttCCATACGATATACTCCTAAATCGCCTTTGCAAGAACACGTATTTTCTCGAAGACATATTGATTCGGTAAGAACTGCCGTGGAAGACGGTAGTTTAATACCACCTACTCCTGGAGCTCCTATATTACGAGAAAGTGCCATTGCAAATTCTACTAATAATAATCTGCAAGGCAATCAATCGCAGACTGAAGAAAATATGATGTACGGGTCGTTGTTCCTTCATCCCACGGCAATGTTTCAGtcgcagcaacagcagcaacagcaacataCCGGGAATGTCACAACCAGCACGACTACCACCACCGCTGGTGAGTGTCTGGCTGACCTCTTAGATTCCTAA
Protein Sequence: MSPEEEGSRGGGSPPATGAALHQPHYPLTASPASGTEPCTRDTISTPISAADTTTNVSESAILTTNLQHNSPSPSPSGCDVEKFDGKIVYNPDGSAYIIEGESELSDDDSLPDGCIVDGRGISISHSLVFPQIANAYYVSRLYAHQAYQHHQQQRSSIIPSNPELPVMHSYRVISYRSSDGSAQLSRSTSTSSISATSVPVKPILMCFICKLSFGYAKSFVAHAQSEHELTLMDDERQILSHATASAIIQVVGKNKQPIVSLLEPVSTAQCPQDSLEQIPGQGSHNGDEEISQESSNKMNTQINTSNTVENLHNFQNKANVNTSLMTSSTNQNQNVLYNYQHHQWINTQVSSSSWSKITESSPNSLSSSITSTPLKSSQSSFSNLSQPPPNFLTGTTIGVCPEHLQGRPSGIECSKCELILATNRLSAASGSLAGIHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPDSETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQQSGSSSNANNPSSSQDQPVPTRSPLHQQNHSPLLSGQSSTQGKSKPTFRCDACNYETNVARNLRIHMTSEKHTHHMLVLQQNIKHIQTLSAFQTHHQQVQQNQIQHQQQLEQFLHLGNLDKPQHAEAALADMAYNQALLIQMMTGGQLPPHVPPEMVGNISALANMGGDIGLSPESMEPPPEPSDPDPCHLYQCCVCNNFATDSIEGLGIHLTSDRTKSREGEILSNVAGHFICKLCSYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGSRNEWKLKYLASPTSTAQIRCHACDYYTNSVHKLALHAATPRHEAAALLLRHLLEASNSISSTSKLYLCALCGFSAKNRLPLLQHVRSIRHLHMEQLHQLQRRTGISASEIPHTDIGDVFQVLSDPNGSTTNLKSKSSDLSPQTKFKEDLHIETQEGEKRYEAKIKQEIEQEQEHDNDVEDINCSYCSFQPSTIEELRNHLQISHAHDNDERIDNSREETNIELLCPLCQDCFKHRSALEKHVMQIHSVNADGLQRLLLLVDQSHWLNSNPRSVHAAIPCPRSPNILLKKNQDDESTEQMGSDDGEETTKCNICPRMCRSVEDLQQHYRESHSSSIPSLAVSEKHVYKYRCGQCSLAFKTLDKLQQHSQYHAIRDATKCAICCRSFRSVQALHKHLETAHTELQEDELTQYKQNLITSHHLIQALTEESFRRQGVLSSEQLVDEDGKVEDDENDLGDLSPLHKEQRLLEDYLNSQSIAEDSYNDPGRKFKCHRCKVAFTRQCYLTGHNKTLLHRKGEKMPYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTLASPLSPTNLSDSQQDFDKKPYKCNICQVAYSQGSTLDIHKRSVLHQTRASKYHESATSSSANSAPITTTPTSFQSHDNVYDNKEKDELCDNKENISKTPEATSTTPTTTPALSNTPVSSTDSTTSTAHSNISPTLMQQQHQQAQLTLAQHMSEMQAAFNVMAASQLQQFHQYPSLMMSMMGLPLGLNMPALAAMNLQPPLVPVMLPPPTFDGSNNSYSSIISTQSDLITKQHLALQQQQVAVWFQNARAKEKKARLAAGLSADGVVIHRGLTGPEECKLCSIRYTPKSPLQEHVFSRRHIDSVRTAVEDGSLIPPTPGAPILRESAIANSTNNNLQGNQSQTEENMMYGSLFLHPTAMFQSQQQQQQQHTGNVTTSTTTTTAGECLADLLDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00714280;
90% Identity: iTF_00714280;
80% Identity: iTF_00714280;