Basic Information

Insect: Eurytoma brunniventris
Gene Symbol: lola
Assembly: GCA_900475205.1
Location: UXGB01000653.1:25636-32585[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0029 0.34 12.1 1.5 1 21 26 46 26 47 0.94

2 11 3e-06 0.00035 21.5 1.7 1 21 150 170 150 171 0.96

3 11 0.025 2.9 9.2 4.0 1 23 179 202 179 202 0.97

4 11 5.9e-05 0.007 17.5 1.1 1 21 235 255 235 256 0.96

5 11 0.00042 0.049 14.8 0.7 3 23 266 287 264 287 0.97

6 11 1e-06 0.00012 23.0 2.3 1 21 332 352 332 353 0.97

7 11 0.00084 0.099 13.8 1.9 1 23 360 383 360 383 0.97

8 11 0.016 1.9 9.8 0.6 3 21 428 446 426 447 0.90

9 11 2.9 3.4e+02 2.7 3.7 3 23 457 478 455 478 0.88

10 11 0.00069 0.081 14.1 4.0 1 21 525 545 525 546 0.94

11 11 1.3e-05 0.0015 19.6 2.3 3 23 556 577 554 577 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0029	0.34	12.1	1.5	1	21	26	46	26	47	0.94
2	11	3e-06	0.00035	21.5	1.7	1	21	150	170	150	171	0.96
3	11	0.025	2.9	9.2	4.0	1	23	179	202	179	202	0.97
4	11	5.9e-05	0.007	17.5	1.1	1	21	235	255	235	256	0.96
5	11	0.00042	0.049	14.8	0.7	3	23	266	287	264	287	0.97
6	11	1e-06	0.00012	23.0	2.3	1	21	332	352	332	353	0.97
7	11	0.00084	0.099	13.8	1.9	1	23	360	383	360	383	0.97
8	11	0.016	1.9	9.8	0.6	3	21	428	446	426	447	0.90
9	11	2.9	3.4e+02	2.7	3.7	3	23	457	478	455	478	0.88
10	11	0.00069	0.081	14.1	4.0	1	21	525	545	525	546	0.94
11	11	1.3e-05	0.0015	19.6	2.3	3	23	556	577	554	577	0.96

Sequence Information

Coding Sequence: ATGCCTGAAAACCCCTGGTTGGAAGTGGTGAGAGTCGTGAAAGTGCCGTCTAAAGCGAACGATTTCACGATACGATTCGTGTGTGACAAGTGCGGTAACACCTACGTTTCCGAGTCGTACATGAAGCATCATCGAAAATACGAATGCGGGGTTGAAGCCAGATTCGGCTGTCCCCATTGTGACTTTCGGTGCGTAAAGAAATCTGCGCCACTTAATGGGTTTCTGCTGCAACAGCAAAGCATCGACCATGTCGACAGTCGGCTTACAGCACCACACAGTGCGTTCATGccaaaacaacaaaatactGACCATCACGACGATCAGCTTTCAGCATCAATTAGTGAGTTCCTGCTGGAACAACATCATGACGATCCGCTTGCGGACCCTCTTGGCGAGTCTCGACTGCAACGTCAAAATTCTGATCTTCATGACGAACAACTCAGTCGGCACAAGTGCGAGAAGTGCGGCAGGAGTTACAAAACGAAGGGGCTCTTATCTCGCCATATACGCTACGAGTGCGGTGTAGAACCTGGGTTTACCTGTCCCTACTGTAGTCATCGCACCAAGCTAAAATTCAACATGAGCGTTCACATTCAGCGTAGGCATTCCGCGAAATGGCATAatgCACGTTGGCTGCCAACACTGAGGCCGAGCAAGATCGTGAGTTTGAGGCCGGGAGAAACTGATAATTgcctgaaaaattattcttgcACGCTGTGCGGAAAGCTGTACAAACGCAAGGATAACATGATGCGTCACAAGCGTTTAGAGTGCGGCATGGAACCCAGTTACGGCTGTCCCTACTGTGATAGGCGTGCGAAGCTCTCGTTCAATTTGCGAGATCACATTCGACGCAAGCATCCAACGAAGGAGATTCGTATACTAAAATTTCGAGCTTCCACAAATAATCaaatgaaatttgtacCAGGATGGACGAAGATTTTCTTCCAGAAAGATGCACAACAACGTGAAAACTGTTCACCTAACGATCAGTACGTTTGCTTTGAATGCGGCGAGTCTTACAAACGCAAAGATCATTTGAAGCGTCACCAGCGCTTTGAGTGCATTGAACTCAGTTTCTGTTGCCCCTACTGTGATATGCAAGTTATGTATGAAAGTACTTTGCAAAGACATATTCAACGCCAACATCCAGGAAAGGATGTCTATGAAAaaACGAAAATTTTGCCTTCACtgagagcgaaaaaaataacgaaactGATGCcaagaaaattagtaaaaaaaccTGGGAATCTTCCAACTACCATAGAGTCACAGCACGCTTGTATCGATTGCAGCGAGGTGTTCAAAAGTCACAAAGATTTATGGCTCCACCAACGCTTGGAGTGTGGTGGGGATCCCAAGTTCGGCTGTCCTCACTGCGATTACTGCTGCAGTGTTGTGTCCATTATAAAGGATCATATAAAAATCAAGCATCCGTCACAGAAGAACTATGCTATCAAATATCCAGgatCTAAATATTTGCCAACATTAAGGGTAGGAAAAATCATTAAGCTGAAGCCGAGAAATATCGCGGAAATGCGTAATAGTCTCCTGCAGGACTTGGATGGACGTTTCGCTTGCTTCGAATGCGGCAGGACGTACAAGCACAAGACACACTTGTTGAGCCACAAGCGCTTCGAGTGCGGCCGGGAACCTACTTTCGGCTGTCCGTACTGCGATCTCCGTTGCAAGCGAAAGTCCAATTTGAAGTCCCACATTCTAATCCGGCATCCGAAGAAAAAAGTCGCTTTCATCTATTTGGCACAAACGCAAAGTGAAGCCAGATAA
Protein Sequence: MPENPWLEVVRVVKVPSKANDFTIRFVCDKCGNTYVSESYMKHHRKYECGVEARFGCPHCDFRCVKKSAPLNGFLLQQQSIDHVDSRLTAPHSAFMPKQQNTDHHDDQLSASISEFLLEQHHDDPLADPLGESRLQRQNSDLHDEQLSRHKCEKCGRSYKTKGLLSRHIRYECGVEPGFTCPYCSHRTKLKFNMSVHIQRRHSAKWHNARWLPTLRPSKIVSLRPGETDNCLKNYSCTLCGKLYKRKDNMMRHKRLECGMEPSYGCPYCDRRAKLSFNLRDHIRRKHPTKEIRILKFRASTNNQMKFVPGWTKIFFQKDAQQRENCSPNDQYVCFECGESYKRKDHLKRHQRFECIELSFCCPYCDMQVMYESTLQRHIQRQHPGKDVYEKTKILPSLRAKKITKLMPRKLVKKPGNLPTTIESQHACIDCSEVFKSHKDLWLHQRLECGGDPKFGCPHCDYCCSVVSIIKDHIKIKHPSQKNYAIKYPGSKYLPTLRVGKIIKLKPRNIAEMRNSLLQDLDGRFACFECGRTYKHKTHLLSHKRFECGREPTFGCPYCDLRCKRKSNLKSHILIRHPKKKVAFIYLAQTQSEAR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -