Basic Information

Gene Symbol
-
Assembly
GCA_018238005.1
Location
DWAJ01014995.1:2449-4248[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.11 9.9 7.4 1.6 1 23 25 47 25 47 0.94
2 16 0.092 8.1 7.7 0.0 2 23 76 98 75 98 0.90
3 16 0.021 1.9 9.7 0.3 2 23 119 141 118 141 0.95
4 16 0.00079 0.069 14.2 3.5 1 23 146 169 146 169 0.95
5 16 0.02 1.7 9.8 2.2 1 23 174 197 174 197 0.92
6 16 0.12 10 7.4 0.5 2 23 200 222 200 222 0.97
7 16 0.024 2.1 9.5 0.7 2 21 229 248 228 249 0.91
8 16 0.00085 0.075 14.1 0.8 1 23 305 328 305 328 0.93
9 16 1.7 1.5e+02 3.7 0.1 2 23 356 378 355 378 0.93
10 16 0.014 1.3 10.3 0.5 2 23 401 424 400 424 0.96
11 16 0.00022 0.019 16.0 0.9 3 20 431 448 430 452 0.93
12 16 0.031 2.7 9.2 0.3 1 23 457 480 457 480 0.96
13 16 0.0015 0.13 13.4 0.1 2 23 486 508 486 508 0.92
14 16 0.00071 0.062 14.4 3.8 1 23 512 535 512 535 0.96
15 16 0.00037 0.032 15.3 0.4 2 23 542 563 541 563 0.96
16 16 0.025 2.2 9.5 2.5 1 23 569 591 569 591 0.97

Sequence Information

Coding Sequence
ATGCGTATACGACGAAACCTCGAAACACTCTTCAATAACACATCAATAATACCCTTCAAATTCCGCGGAAAGTACCTTTGCTTCTTCTGCAGCAAATACGTTGAAGAATACTCCGAATTAAAGAGACATACAAAAGAACATGGGGTTTGCACTATAAGCACTCATTCTCTAAAAGCTATTCGCGGTATATCTAACGtagaaattaaaatcgatGTTTCGGAAATTAGCTGTGAAATTTGCAGCGAAACATTCGTCTCCATGAATGAGGTACTCGACCATCTTCTAGCTGCACACAAAATCGACTACGATAAAGATATAGAAATGCCCTTCGAGGAATACCGCTTGAAGGATCTGACATGTCTCGTTTGTGACGCGAAATTCACGTTTTTCGGGTATTTAGTGTCCCACGTTAATAGTAATCACCCCAAGAATAATTTCACCTGCGAAACGTGTGGACAGAAGTTCAATAAGAAACGCGACCTCTTCTCCCACTCAAAAAATTATCACCGAGAAGGTGGATTCGTTTGCGAGTTGTGCCACCAAACATTCACCTCACTTAACATactaaacaaacataaaatcaaCAGACACATAGGCAGGTGTAATATATGTCTTCTGAAACTACCCTCCGCGGCTTTGAAACGAAAACACATGAAAACCGAACACGCTGACGACGGTTCGCTAACTTGCAAAATCTGCGACAAACAGTTCCACACAGACATCGGCTTGAAAATGCATTCCAGAAATTGCAgaaactatgacgtcataaccGATGATAAGGATATTGACGTCATGGACTCTGATATCAAGTACGATGTTCCAAAGAGGAATAGTGTCAAACAGCTCCGCGAAAATATAGCTCTAGTCATAAGCCTATCTACGGCTATTCCTTTCAACTTCTTCCATAATAAATTCAACTGTTTCTATTGCTCAAAAGACTTCCAAGACCCAGACTCGCTCAAAGAACACACTATACTCAACCATCCAGTGTGTGATGTTCGCGAGAAGAGCATTCTTAAATGCAGGGAATCTGAGTCGTCCGTCAAAATTGATATTTCCTCACTCTCCTGCAAACTTTGCTTCGCAGCCATGAGCGATTTAGATTCCCTTCTCGACCATTTGATATCCCGACACAACGCCAACTATGATAAGTCAATAAAAACCTGCCTTCAACCGTACAAACTGGTCAATGATCATATGAAATGCCCCCTTTGTCCAAATGAGGTCTTTCGATTCTTTGGCACTCTGTTAAAACATATGAATAAAACGCATACAGATAACAAGAACATATGCGTGCATTGTGGCCAGTCGTTCCGTCGCGAACAGAATTTGAGGGTTCATCTATGGAGGAGGCATAGCGAAAGTAAATTTAACTGCTCAATATGCGGGGCAGATTGCGAACTACCCTCAAGATTATTCATGCACATGGCCAAAGAACATGGTGTTAAGGCAGCGAAATGTCCAATGTGCCCGGAAGCTTTCGAAACTCAATACCTTAGACAGAAACATTTGATCGACGCCCATAACTCCGGTCACAAGTGTTCCTACTGTGGAAAACTATTTACGAGAGAATCCTTTATGAAAGACCACGTCAGCAGAACCCATCTAAAACAGAAGAATGTCGAATGCAATATTTGTAGTGCGaagttctttaataatattctgttGAGACGCCATATGGTGAAGCACAGTGGTGTGAAGAATTTCCACTGTGATCTGTGTGGAGAGAGGTTCTTTTGGAAGAAGAGTCTTAGTTCGCATATGGTTAAGCATAAAAAGAACGACGAATTGCCTCATTAG
Protein Sequence
MRIRRNLETLFNNTSIIPFKFRGKYLCFFCSKYVEEYSELKRHTKEHGVCTISTHSLKAIRGISNVEIKIDVSEISCEICSETFVSMNEVLDHLLAAHKIDYDKDIEMPFEEYRLKDLTCLVCDAKFTFFGYLVSHVNSNHPKNNFTCETCGQKFNKKRDLFSHSKNYHREGGFVCELCHQTFTSLNILNKHKINRHIGRCNICLLKLPSAALKRKHMKTEHADDGSLTCKICDKQFHTDIGLKMHSRNCRNYDVITDDKDIDVMDSDIKYDVPKRNSVKQLRENIALVISLSTAIPFNFFHNKFNCFYCSKDFQDPDSLKEHTILNHPVCDVREKSILKCRESESSVKIDISSLSCKLCFAAMSDLDSLLDHLISRHNANYDKSIKTCLQPYKLVNDHMKCPLCPNEVFRFFGTLLKHMNKTHTDNKNICVHCGQSFRREQNLRVHLWRRHSESKFNCSICGADCELPSRLFMHMAKEHGVKAAKCPMCPEAFETQYLRQKHLIDAHNSGHKCSYCGKLFTRESFMKDHVSRTHLKQKNVECNICSAKFFNNILLRRHMVKHSGVKNFHCDLCGERFFWKKSLSSHMVKHKKNDELPH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01205947;
90% Identity
iTF_00710444;
80% Identity
-