Basic Information

Insect: Eupristina koningsbergeri
Gene Symbol: zfh1
Assembly: GCA_018907245.1
Location: JACCHV010000144.1:41405-47875[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 3.8e-06 0.0014 20.7 7.8 1 23 13 35 13 35 0.99

2 5 9.5e-06 0.0036 19.5 1.9 1 21 41 61 41 62 0.95

3 5 5.7e-05 0.021 17.0 4.7 1 23 573 595 573 595 0.94

4 5 1.3e-05 0.005 19.0 8.1 1 23 601 623 601 623 0.98

5 5 0.001 0.38 13.1 4.3 1 21 629 649 629 650 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	3.8e-06	0.0014	20.7	7.8	1	23	13	35	13	35	0.99
2	5	9.5e-06	0.0036	19.5	1.9	1	21	41	61	41	62	0.95
3	5	5.7e-05	0.021	17.0	4.7	1	23	573	595	573	595	0.94
4	5	1.3e-05	0.005	19.0	8.1	1	23	601	623	601	623	0.98
5	5	0.001	0.38	13.1	4.3	1	21	629	649	629	650	0.96

Sequence Information

Coding Sequence: ATGATCAGCCACGACGAAAGCGCGGTTCTCCGCAAATTCAAATGTCCTCATTGCGAAAAAGCTTTTAAATTCAAACATCATCTTAAGGAACACTTAAGAATACACAGCGGGGAGAAGCCTTTCCAATGCAACAACTGCGGCAAACGATTCTCGCACTCAGGTTCCTATTCGTCGCACATGACGTCGAAGAAGTGCCTTGTGAACCACCCGCAACAGAATCAGCATTCGTTTCATACGAGGCGCGAAGTTGAAATATTATCTGCGAATAACAACACCTTTATGCCGATTCTGCCAAAACTTTCACCATCGGACTATCGAGATATACAACGAGAAGCAGCGGGTATATATGATATGCCTACGCTACTACCTCACATGATGGGCTTCGGAAATTACTTTTTGCAATCATCTCTTGGAAAAATTTTAAATCAGCTTCACACTAAACAACAAGAACAACATTATCATCACCAATCTTTACATTATCATCACCAAACTATGCATTATCATCAGCATAATAATCACAATAGCCATACCAATCATCATTACAATCATCGATCAGATGAGATGGGTAGCGAGCATTATGATGCTCTTAGTCAGCAAAGTGAAAATGCTCTTAGTCCCTCGACTACAGCACCCGACTCCGAGGGTACAACCACCGAAGGCACTGAAGGTGGAAAAGAGTCACCTGCACCACCCTCCGGTCTTATGAATCTTCATCATCCTGAACATTCTCTCGATGCTGTGAGGCGACTTTTGGAAACTGTTAACACTTCCGTTACAAAACAATTGTTAGAGGCTAATGTAAGGAAGCTTGCATCTTCTCCTGCAATGATGATCAAGCGCGACATAGATGAATACTATCAGGATCAGGACAGTGAGATGTCGAGTGAGATGACGCACTATCCCGCCGATTGGTCAGCGATGGAACATTGCGATTCTCAAGGCGAGGCTCCAAATGTAAAACTCGAGGAGGTTCATCATAAGCCACTTCCATTGCTACGGCAGGGAGTGAAACGAAAAGCCGAGAGCAATGGTTTATCTGCACACACTTCCGAAGCTGAGACAGACGATGACGATGAATTACTTCAGAATCATCAACAGGGTGTTTCGGGCACTGGCGTAAGTGGTAGTAGCGGTGGTGCACGTAGAGTAAGGGCAAGGTCCCTTATCGACGATGAGCAACTCGCTGTCCTCAAGGGCTACTACGCCATAAATCCACGACCAAAAAAGGAGGAAATCATTATGATCGCCAATTACATTAATTTTCCGACACGCGTTGTCCAGGTTTGGTTTCAAAACTCCCGTGCAAGAGATCGTCGTGAAGCAAAAATACCAGCTCTGGTACCGCTTTCAAGTTTGAGTAATCATGTGTTCAATGATCAGCCCCTGGATCTCTCAAAGAAAGATGTTCTCAGGACAATATCAACAGTTAAGGACAGCAGTGATGCCTCGAGCAGGAACACCGTGTCACCTTTCGGTCCAAAAGAGGATGCTCTTGTACCCAAAGTACTGGCAAATAATAACGTAGAACTCGAAGATGCCGAAGAGTCACGTCTTGTTATTGACGAAGAGACGACCGATTTCGCTGAAAGCAAACCAGCTATACCTGTAGAAGTAATCATTAAGACCGAAACCCCAGTTATACAAATTAAGAATGAGGTTGAGACAAGGGTGAATGTGGATGCTATACCGCAATCGGAAACGGAACAAGAAGGCGTATACTTCTGCAATCAGTGTGATAAGACTTTTTCCAAGCATAGTTCTCTTGCAAGACATAAATATGAACATTCTGGACAAAGGCCATATAAATGTCAGGAGTGTCCTAAAGCTTTTAAGCACAAGCATCACCTAACGGAACATAAGCGACTCCACAGCGGCGAGAAGCCTTTTCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCTGGTTCTTATAGCCAGCACATGAATCATCGTTACTCATACTGCAAGCCTTACAGAGAATAG
Protein Sequence: MISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFQCNNCGKRFSHSGSYSSHMTSKKCLVNHPQQNQHSFHTRREVEILSANNNTFMPILPKLSPSDYRDIQREAAGIYDMPTLLPHMMGFGNYFLQSSLGKILNQLHTKQQEQHYHHQSLHYHHQTMHYHQHNNHNSHTNHHYNHRSDEMGSEHYDALSQQSENALSPSTTAPDSEGTTTEGTEGGKESPAPPSGLMNLHHPEHSLDAVRRLLETVNTSVTKQLLEANVRKLASSPAMMIKRDIDEYYQDQDSEMSSEMTHYPADWSAMEHCDSQGEAPNVKLEEVHHKPLPLLRQGVKRKAESNGLSAHTSEAETDDDDELLQNHQQGVSGTGVSGSSGGARRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIANYINFPTRVVQVWFQNSRARDRREAKIPALVPLSSLSNHVFNDQPLDLSKKDVLRTISTVKDSSDASSRNTVSPFGPKEDALVPKVLANNNVELEDAEESRLVIDEETTDFAESKPAIPVEVIIKTETPVIQIKNEVETRVNVDAIPQSETEQEGVYFCNQCDKTFSKHSSLARHKYEHSGQRPYKCQECPKAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01218964;
90% Identity: iTF_00707739;
80% Identity: iTF_00707739;