Basic Information

Insect: Eupristina koningsbergeri
Gene Symbol: ZFHX3
Assembly: GCA_018907245.1
Location: JACCHV010000014.1:1291873-1309532[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.015 5.8 9.4 0.2 2 23 46 68 45 68 0.96

2 11 0.023 8.5 8.8 2.5 3 23 87 108 86 108 0.95

3 11 0.001 0.38 13.1 0.3 2 23 171 193 170 193 0.92

4 11 0.0013 0.47 12.8 1.3 1 23 210 232 210 232 0.97

5 11 0.061 23 7.5 3.0 2 23 239 261 238 261 0.96

6 11 0.034 13 8.3 5.8 1 23 350 374 350 374 0.91

7 11 0.002 0.76 12.2 0.6 1 22 394 415 394 418 0.89

8 11 0.0028 1.1 11.7 0.3 1 23 459 483 459 483 0.92

9 11 0.0064 2.4 10.6 0.2 2 21 530 549 529 550 0.94

10 11 0.061 23 7.5 2.0 2 19 691 708 690 713 0.91

11 11 0.035 13 8.3 0.7 2 21 964 983 964 987 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.015	5.8	9.4	0.2	2	23	46	68	45	68	0.96
2	11	0.023	8.5	8.8	2.5	3	23	87	108	86	108	0.95
3	11	0.001	0.38	13.1	0.3	2	23	171	193	170	193	0.92
4	11	0.0013	0.47	12.8	1.3	1	23	210	232	210	232	0.97
5	11	0.061	23	7.5	3.0	2	23	239	261	238	261	0.96
6	11	0.034	13	8.3	5.8	1	23	350	374	350	374	0.91
7	11	0.002	0.76	12.2	0.6	1	22	394	415	394	418	0.89
8	11	0.0028	1.1	11.7	0.3	1	23	459	483	459	483	0.92
9	11	0.0064	2.4	10.6	0.2	2	21	530	549	529	550	0.94
10	11	0.061	23	7.5	2.0	2	19	691	708	690	713	0.91
11	11	0.035	13	8.3	0.7	2	21	964	983	964	987	0.89

Sequence Information

Coding Sequence: ATGCTAAAACATTCTGTTTCATCACGAATTGAAATAAACACTAAAAAACGACGAGAGGATGAGACTAATTATGGTAGTGAAATTAAACAAGAAATAGAACATGAACAAGAACAAGAGAATGAGACTGAGGATGTAACATGTTCTTTTTGTTCTTATCAGGCATCATCAAATGGAGAGTTAAGAAATCACCTTCAAATTGTTCATACTCATGAAATTGATGTAGATGATCTAAAAGAAAATTTGAATTCAGATTTATTATGTCCTTTGTGCCAAGATTGTTTTAAGCACCGAAATGCATTAGAAAAACATGTAATGCAAATTCATTCGGTTAATTCGGATGGTTTACAAAGATTATTACTGCTTGTTGATCAAAGTCATTGGTTAAATAATAATCCACGCAGTATAAATGCATCAATTCCAGGTCCAAGATCTCCTAATATTTTATTTAAAAAGAATCAGGAAGAAGAAAATATTGAACAAATTATTAGTGACGATGGAGATGAAACTACAAAATGCCTTGTTTGTCCAAGAGTATTCCGATCAATAGATGAACTTCAGCAGCACAATAAAGAATCACATTCGATTCCTGTACCTAGTTTAGCTGTAAGTGAAAAGCATGTCTATAAATACAGATGTGGTCAATGCAGTTTAGCATTTAAGACATTAGAAAAACTTCAACAACATTCTCAGTATCATGCTATCAGAGATGCAACTAAATGCGCTATTTGCTGTCGATCTTTTCGTTCAGTACAAGCTCTTCATCGACATTTGGAAACTGCTCATAGTGACTTACAAGAAGAAGAATTAACGCAATATAAACAAAGTTTACTAAGTTCTCATCCACTTTTACAAGCATTAACGGAAGAAGCATTTAGACGGCAAGGTATATATGGTAGTGAACAGTTAATTGATGAAGAAGTAAAAATTGATGAAGATGAAAATGATATTAATGATTTATCACCATTACATAAAGAGCAACGACTACTCGAAGATTATTTGAATAGTCAATCAATAGCAGAAGATTCTTACAATGATCCTGGTCGAAAATTTAAGTGTCATCGGTGCAAAGTTGCTTTTACAAGACAATGTTATCTTACTGGTCACAATAAAACATTATTACACCGTAAAGGTGAAAAAATGCCATACCCTATGGAAAAGTATTTAGATCCTAATAGACCATATAAATGTGATGTCTGTAAAGAAAGTTTTACACAAAAAAATATTCTTCTTGTTCATTATAATAGTGTTAGTCATTTACATAAATTAAAAAGAGCTATGCAAGAACAAGGCAACAATAATACGTTTATTAATGTAGCATCGCCTGTAAGCCCTACCGATTTGAGTGATGGTCAACAAGATCACGATAAAAAGCCATATAAGTGCAATATTTGTAAAGTTGCCTATTCTCAAGGAAGTACTTTGGATATTCATAAAAGAAGTGTTCTTCATCAAACTCGCGCTAGCAAAATTCATGATTTAGCAGTTACTGGTCAATTAGATCTAGCACGACCACTAATTGAACAGCCAATATTAACTTCTAATAATTCATTATGTAATAATAACTTAGATAATAATACCCAAATGCTATCATGTACGAAATGTAATGCATTATTTATCACTCAAGACCAACTCTCTACTCATCAACAATTGTATTGTATCTTTAGTAATCCCTTAGCTTTATTTCAACAATTAGCAACATCTCAACATTTAACAATGTCTCCGTCTAAAACTCCACCTCCGTCAGTATCATCTTCCGGTTCACAAGAAAAACATCTGTCACAATCAAATCCTCCATCACTTTTATCTCAAGATATATTACCTAAACATAAAACGTCTCAAATGTATAAACATTTGTTAGAAAGTTTTGGGTTTGATTTAGTTATGCAATTTAATGAAAATCACCAAAGAAGACAAAGAAAAGAAGAAGTTGTTGCTGTATATCAATTACATCAAGAACATCAAAGTGAAGAGCAGCAAAAATATAATTTTGATGGTCAAATTTGTCAAGAAAAAGAGTCAGATATTGAAGATCCTGGTGAAGAAGAATTTATACCTGAAATTAAAAAAAGTACATGTCAACACTGTAATAAAGAATTTAGCAGTGTATGGGTACTTAAAGCACATTGTGAAGAGGTACATAGAGATTTAGTTCCTCGTGAATTTCTTGAAAAATATGCACAACAATTTAAATGTGAATATGAGAAAAAAATTGTCATTGTAACAGCAGCCACATCTTCTTCTACCACTACAGCACCCATCACTATAACACCATCATCATTTCAATCTCAAGATAATAGTATTTATGAAAATAAAGATAAAGATGAATTTTGTGAAAATAAAGAGCGTATAAATAAAACACCAGAAGCTACTTCTACAACTCCTGCAACAACTCCAGCCTTAAGTAATACACCTGTATCGAGTACAGATTCTGCTACACCAACAGTACAAAGTAATATTTCTCAAAATCTTACCCAACAACAACAAGCTCAACTAACTTTAGCCCAACATATGACTGAAATGCAAGTTGCATTTAATGCTATGGCTGCTTCTCAATTACAACAACAACTTCATCAATATCCAAGCTTAATGATGAGTATGATGGGCTTACCATTAGGACTTAATGTGCCAGCTCTTGCAGCTATGAATCTTCAACCTCCTATAGTACCAGTGATGTTACCTCCACCAACATTTGATGGAAATAATAGTGTATATACACCTTTATCAACACAGTCTGATTTACTTTCAAAACAGCATATTTCCGTACATCAGCAGCAACATGCAGTTGCAGTATGGTTTCAAAATGCACGTGCTAAAGAAAAAAAAGCTAGATTAGCAGCTGGATTATCAGCAGAAGGTGTAGTAATTCATCGAGGTTTAACTGGACCTGAGGAATGTAAATTATGCTCTATTCGTTACACTTCTAAGTCGCCTTTGCAAGAACATGTATTTTCGCGAAGACATATTGAATCGGTAAGAACTGCTGTAGAAGATGGTAGTTTAGTACCGCCAACTCCTGGAGCTCCAATATTACGGGAAAGTGCCATTGCAAGTTCGACAAATAATAATCTGCAAGGCAACCAATCGCAGACTGAAGAAAATATGATGTACGGGTCGTTGTTCCTTCATCCCACGGCAATGTTTCAGTCGCAGCAACAGCAGCAACAGCAACATACCGGGAATGTTACAACCAGCACGACTACCACCACAACCGGTGAGTGTCTAGCTGACCTCTTAGATTCCTAA
Protein Sequence: MLKHSVSSRIEINTKKRREDETNYGSEIKQEIEHEQEQENETEDVTCSFCSYQASSNGELRNHLQIVHTHEIDVDDLKENLNSDLLCPLCQDCFKHRNALEKHVMQIHSVNSDGLQRLLLLVDQSHWLNNNPRSINASIPGPRSPNILFKKNQEEENIEQIISDDGDETTKCLVCPRVFRSIDELQQHNKESHSIPVPSLAVSEKHVYKYRCGQCSLAFKTLEKLQQHSQYHAIRDATKCAICCRSFRSVQALHRHLETAHSDLQEEELTQYKQSLLSSHPLLQALTEEAFRRQGIYGSEQLIDEEVKIDEDENDINDLSPLHKEQRLLEDYLNSQSIAEDSYNDPGRKFKCHRCKVAFTRQCYLTGHNKTLLHRKGEKMPYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQGNNNTFINVASPVSPTDLSDGQQDHDKKPYKCNICKVAYSQGSTLDIHKRSVLHQTRASKIHDLAVTGQLDLARPLIEQPILTSNNSLCNNNLDNNTQMLSCTKCNALFITQDQLSTHQQLYCIFSNPLALFQQLATSQHLTMSPSKTPPPSVSSSGSQEKHLSQSNPPSLLSQDILPKHKTSQMYKHLLESFGFDLVMQFNENHQRRQRKEEVVAVYQLHQEHQSEEQQKYNFDGQICQEKESDIEDPGEEEFIPEIKKSTCQHCNKEFSSVWVLKAHCEEVHRDLVPREFLEKYAQQFKCEYEKKIVIVTAATSSSTTTAPITITPSSFQSQDNSIYENKDKDEFCENKERINKTPEATSTTPATTPALSNTPVSSTDSATPTVQSNISQNLTQQQQAQLTLAQHMTEMQVAFNAMAASQLQQQLHQYPSLMMSMMGLPLGLNVPALAAMNLQPPIVPVMLPPPTFDGNNSVYTPLSTQSDLLSKQHISVHQQQHAVAVWFQNARAKEKKARLAAGLSAEGVVIHRGLTGPEECKLCSIRYTSKSPLQEHVFSRRHIESVRTAVEDGSLVPPTPGAPILRESAIASSTNNNLQGNQSQTEENMMYGSLFLHPTAMFQSQQQQQQQHTGNVTTSTTTTTTGECLADLLDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00969111;
90% Identity: iTF_01219318;
80% Identity: -