Basic Information

Insect: Euplagia quadripunctaria
Gene Symbol: Zfhx3
Assembly: GCA_963859945.1
Location: OY982574.1:13646982-13658245[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.8 1.8e+02 3.9 3.5 1 23 375 398 375 398 0.92

2 15 0.018 1.8 10.2 0.1 1 23 405 428 405 428 0.95

3 15 0.0036 0.36 12.3 2.6 2 22 483 503 483 506 0.91

4 15 0.29 29 6.3 0.6 1 23 518 543 518 543 0.94

5 15 0.013 1.3 10.6 1.3 1 23 561 583 561 583 0.97

6 15 0.0024 0.24 12.9 0.3 2 23 590 612 589 612 0.95

7 15 0.0003 0.03 15.7 3.1 1 23 718 742 718 742 0.92

8 15 0.012 1.2 10.7 0.7 1 22 762 783 762 786 0.89

9 15 0.0012 0.12 13.8 0.2 1 23 833 857 833 857 0.93

10 15 2.6 2.6e+02 3.3 0.0 3 21 932 950 931 951 0.91

11 15 0.89 89 4.8 3.5 2 19 1041 1058 1040 1063 0.91

12 15 3.1e-05 0.0032 18.8 2.9 1 23 1570 1592 1570 1592 0.99

13 15 0.00083 0.083 14.3 0.3 1 23 1679 1701 1679 1701 0.98

14 15 0.0078 0.78 11.3 0.4 2 23 1839 1861 1838 1861 0.97

15 15 0.5 51 5.6 2.1 2 22 2090 2110 2090 2113 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.8	1.8e+02	3.9	3.5	1	23	375	398	375	398	0.92
2	15	0.018	1.8	10.2	0.1	1	23	405	428	405	428	0.95
3	15	0.0036	0.36	12.3	2.6	2	22	483	503	483	506	0.91
4	15	0.29	29	6.3	0.6	1	23	518	543	518	543	0.94
5	15	0.013	1.3	10.6	1.3	1	23	561	583	561	583	0.97
6	15	0.0024	0.24	12.9	0.3	2	23	590	612	589	612	0.95
7	15	0.0003	0.03	15.7	3.1	1	23	718	742	718	742	0.92
8	15	0.012	1.2	10.7	0.7	1	22	762	783	762	786	0.89
9	15	0.0012	0.12	13.8	0.2	1	23	833	857	833	857	0.93
10	15	2.6	2.6e+02	3.3	0.0	3	21	932	950	931	951	0.91
11	15	0.89	89	4.8	3.5	2	19	1041	1058	1040	1063	0.91
12	15	3.1e-05	0.0032	18.8	2.9	1	23	1570	1592	1570	1592	0.99
13	15	0.00083	0.083	14.3	0.3	1	23	1679	1701	1679	1701	0.98
14	15	0.0078	0.78	11.3	0.4	2	23	1839	1861	1838	1861	0.97
15	15	0.5	51	5.6	2.1	2	22	2090	2110	2090	2113	0.88

Sequence Information

Coding Sequence: atgCTTGTGTTACAGCAAAACGTGAAGCATATGCAAACGTTATCAGCCTTACATCACCGACAGCAAAGTCACCAACAACTAGAGAGTTTACTACACTTCCATGGAGGTGATGCGCCACCACCAAACCCAGAAGCTGCCTTGGCTGATATGGCTTACAACCAAGCATTGATGATTCAACTGATGACTGGAGGTCCTGGCCCTTCTCCGCCTGAGCTTGGCGCCCATTTGGACGTTGGCTTAAATCCTGAAGCAATGGAACCTCCACCAGAACCAGCGGATCCTGAACCAGAAAGAACGTTCCACTGTTGTATCTGTAACTGCTTCTCAACTGACTCCCTAGAAGCTCTCGGTCACCATTTAGCTCAAGACCGCACAAAAATTAGAGAGCAAGAAATTCTGGCTTTGGTTGCAGGTCATTATGTTTGTAAACTTTGTACATACAAGACGAATCTTAAAGCCAACTTCCAGCTTCATTGTAAAACTGATAAGCACCTACAACGGCTGCAGCATGTAAATCATGTTAAGGAAGGTGGACCCAGAAATGAATGGAAGTTGAAATTCTGCGGTGGTGTTGGTACAGGAGGTGCAAGTGTTGGTGGAGTTCAGGTGCGATGTTGCGCTTGTGATTACTACACGAATTCGGCTCATAAACTGCAGCTTCATGCAGCTGGGGCAAGGCATGAAGCAGCGGCACTGTTACTGAGACATCTCCGTGAGTGTGCATCGCGGATACCTCGCGAACGACCCCGTGTGTACCGTTGCGCTCTTTGTGGGTTCGGTGGCCCGCACCGCTTACCATTGCTGCAACACGTTCGCTCCGTGAAGCATTTGCAAATGGAACAAATCCATCAACTACAAAGGCGTTCAGAAGGCAAAGACCCTACGCCTGATGTGGCAGAGCTGTTCCAAGTGATACCCCAACCGACAGAGCTTCCCAGTCCTTACGATCAACAGGAAAATGACAATAAGGAGCCGATTGATCAGAAGCCTGAGTTAACACAAGAGCAAAAGATGATGAGGTTTTTGGAACAACATCAGCAGCAACAGCAACAACAGCAGGTTCAACAGCAATCTCAGCAAGCGGCCAGCGAGCGAGAAGAAGAGCGTGAGACGCCAGGACCGCACGCGTGCCCCTACTGTAACTTCAGCTGTACAGGCGAAACACGCCTACACGCTCATGTCACTTCTGTGCATAGTGATAGCGCTCGCCAATTTATTTGCCCACTTTGCCAAGACGGTTTCAAAGAACGTTCTGCACTCGAGCGACATGTCATGCAAATTCACTCGGTCAACTCAGAGGGATTACAGAGATTATTGTTACTCGTTGACCAAAGCCATTGGTTGAACGGTGGATCCCAATCTCAAAGAGACGAATCTCGACAGGGAGAAGATGAAAGAGAGATATCATCACCAAGATCAGAAGGTAGTGCTGATGGTGAAATGGAAAGATGCTCAACGTGCAATCGAACTTTCCGTAATGTTGACGAACTGTGTCAACATCAGAATGAGACTGGACATCTTGAATTAAAACAAACACCTCAAGGACCAGGATATGTGTGCTGGAAGAAAGGATGCAATCGGTACTTTGATGCTGCTCATGCACTACAGAACCACTTTAGAGAAGCACACGCGCGCAATTCTATCGCAAACATGTCCGTATCTGAGAAACATGTTTACAAATATCGCTGTAATCAATGCAGCTTAGCATTTAAAACTGTTGAGAAGTTACAGCTACATTCACAGTATCATGTTATTAGAGACGCGACTAAATGTGTGCTTTGCGGAAGAAGCTTTAGATCAGTGCTGGCTTTACAAAAACACGTTGATACTTCACACTCTGAATTATCTGAAGAAGAGCTCTCCGCTTTTAAAAGAAGCTTAGCATCAAACCCATTGTTACAAACTGGACAAGGGACGGCATTAGATGCTGCTACTGCTGAACTTTTACGCAAAGAAGCATTGAGAACTCCTGAGGATGACATGGCTGATTTAGAAGATAGAGATTCTAGTGCTACTGTTGCTGATGAGTCAGGACATAATGACGCCGAAAATTCTGACGATTCCATAATCTATAAAGATCAACAATTTTTAGAGGACTATTTGAACTCTCAAGCTATGGCAGAAGATTCATACAATGACCCGAACAGAAAATACAAATGTCATAGGTGTAAAGTGGCCTTCACTCGTCAATCCTACTTGACAGCACATAACAAGACTTTACTACATAGAAAAGGGGAAAAACTAACCTACCCAATGGAAAAATACCTAGACCCTAATAGGCCTTTCAAATGTGACGTATGCAAAGAATCATTTACGCAAAAGAATATCTTGCTGGTACACTATAACAGCGTAAGTCATTTGCATAAACTGAAGAGAGCAATGCAAgaacaacaaaataacaacaATCCACCCGTATCACCGGGGGCAGGTTCAGCACCATCTAATTTAACCCTCACTCCCAAGAGTACATCAAGTGAGGAGGATGATCGAAAACGTTACAAATGTAATATTTGCAAAGTCGCATATACGCAAGGCAGCACACTGGACATTCACATGAGATCAGTATTGCATCAAACTCGCGCCGGTAAATTACAAGAACTAGCCGCCGCTGGACACGTGGACTTGACAAGGCCGTTGGTTGAGCAACCGGACAGAAACGATCCCGCGAAAATTTTACAAGACGTGTTGTCGCCGAAAAATACATCCCCTTCGTCAACAAGCAGTGGGGGACCGCGTTCCTCGCCCCCTGCGCGCCCAGGTAGCCCGCGATCCCCGCGAGCAGGTAGCGCCGCGTGCGAACGCTGTCACGCGTCATTCCCTACCGGGGAGTTACTCGACGCACATCGAGCGACTTCATGCCCGTTTGGCGATGCGCGGGCGCATTCGCCGCTGGGTGAAGCTGAAACAGCTGCTTTAGACGAAATGGTCGCCAAGGGCAATCCGCCCAAACGAAATTCACAAATGTATAAACAATTACTAGAAACTTTCGGCTTCGATCTCGTTATGCAATACAATGAAAATCAGCGAAGAAAAATGCAGGAAGAGCGGGAAATGGTGCGTGTACCAAGTCCACCGCCACCACCTCCCGAAGAGAAACCGCCGGACGGTGAAACCAAATCGACGTGTCAACATTGTAACAAGGAGTTTTCTAGTGTGTTCGTTTTAAAGACTCATTGTGAGGAAGTGCACAAGGATAAAGTACCGCTTGAGTTTTTGGAACAGTTTGCGGAACAGTTTAAATCGGAGTATGAAAGGAAGTCAGGCGCACCAAACTCCCCTCGTGCCGCCTCACCTGCACCACAAGGTGACAGGTCACCTTCTCCTCGTGGTGACAACAATGGGAACTTTAACGAAAATGGAAGTGCACCAGGAGATGCTCAGGCTGGTGCTTTACTGGCAGCGCAAGTGCAGGAAATGCAAGCAGCACTAAACATGATCCAGCTACAGCAGCAACTAGGACAGTTGCACCCTATGGTAGCACAGATGTTGTCTCTTGGTCTACCGCTTGGGCTAAATGTGGGCGCGCTGGCCGCGATGAACCTGCAACCACCACTAGTGCCATTAATGCTACCACCTCCACCCTTTGACACCATGCCATTCGCACATGATGCGCAACTTAAACAACAGCAACTTCTGCAGCAACAACAACAGGCTAATGCTGCTGCGGGTCAAAAAAGAGCTCGTACTCGCATTACTGACGAACAACTTAAGATTTTGCGAGCGCACTTTGACATCAACAACTCGCCAAGCGATGAAGCCATTGCAAAAATGGCACAGCAGTCTGGACTAGCTACAAAGGTAATCAAACACTGGTTCAGAAATACGCTCTTTAAGGAACGTCAGCGTAATAAAGACTCACCCTACAATTTCAACAACCCACCTTCCACCACACTCAATCTAGAAGAGTACGAAAAGACTGGTGAAGCCAAGGTGACAACCTTAGATTCGTCCGCAAGCTCTGATGAAGGTAAACCACCTCCTGAAAAGAAAgctaaaattgaagaaaacagTATAATAATGCAGCAAGAGGTGAAGTCGGAACCTCATGACGAACCTACCATCGAAGAAAAGTACCACTCTTATGATGATCGCCACCAAGaagataaaagttttatttttccacATGCACCATCTCAAAGCCCTGCACCAATAAGCCAAATTAATGACCATCATCAAAACAAGTCGCGACCGCAGACTCCAACCCATATGTCGCTAAACTCACTCATTCAATCTCAGTTAGATTCCATCCCGGCTACGAGTATACCGCAACCACCACATCCATCGATGCTTCCTCCAAAACTGAATCCAAATTTCACGTCCCCAAACTCCGCGCCCCCGAACGTCCTACCTTTGACCCCAAATCGCAGCCTCAGTCCTGGCAGGGGACCGGCCGATTTCGGACTTTCCGGGGGCAATTCGAACGGATCCAACAGCTCGGGGTCTTCTGGCAAACGCGCCAACAGAACTAGATTCACTGATTATCAAATCAAAGTATTACAAGAGTTTTTTGAGAATAACGCATATCCCAAAGATGACGATCTCGAATATTTATCAAAGTTACTGGGGTTGAGTCCTAGAGTAATTGTTGTGTGGTTTCAAAACGCACGACAAAAAGCAAGAAAAGTGTATGAAAACCAACCAGCTGCAGATCCACCAGCGAGCGCTACAGATGACGCAAATAGATTTCAACGCACTCCAGGACTTAACTACCAATGTAAAAAGTGCCAATTAGTATTCCAGAGATACTATGAACTTATACGACATCAAAAGACACACTGTTTTAAAGAAGAAGATGCGAAGCGATCAGCACAGGCACAAGCGGCTGCAGCGCAGGTAGCTGCCACATTAAGTAGTGAAGATTCAAACTCGAGCAATGTAGAACATCATACTCCTCACGTACCAGTTTCTCCAGCGCCACCTCGTACTCCAACACCAGCTGCGCCTAACTACCCAGCTTCACCAGCACCTCCAACGCCTATAACACCAGTAACACCTCTTTCGCATACCGCTCCCCGTGAAGAAAAAGATGGAAATTTTCAATGTGATAAATGTAACCTAGTCTTCCCTCGATTTGATTTGTGGCGGGAACATCAACTTGTTCACATAATGAACCCTAACTTATTTCCCACCTATCCACCGGATTCCCCTTTTGGGATATTGCAGCAACATGCTCAACTACAACAGCTAAACGCTAGCCTCGGAGGAGATGAAGCTCGCCACCCCTTAGTTGCTGCATTAAACCAACAAGTGGTAAAGAGGAAATTTGACGAATTTGAAGAAATTGATACTGGGGAACAGCCTAAAGACAAAAGATTGCGGACTACCATCTTACCCGAACAACTGGATTACCTCTACCAAAAGTACCAAATTGAATCAAATCCGTCGCGAAAAATGCTTGAAAACATTGCACGCGAAGTTGGTTTAAAGAAACGAGTGGTACAAGTTTGGTTTCAAAATACACGAGCACGTGAGAGGAAGGGACAATTTCGTGCGCACGCACAAGTCATAAATAAACGATGCCCCTTTTGTCCAGCTTTGTTCAAAGTAAAAAGCGCACTCGAAAGTCATCTCAGTACAAAACACGCGGACCAGTGCGCGAGAGGTGAAATCAACGTCGATGCGCTACCGGATGAAGAATTAAGTACAGAGTCAACCCCCAGTTTTGGATCCCAACAAAGTGACCGGCAGCAAAATTTTTCCCAAGCGGGGGCTCCCATGTTGCcccctatttttccaccttTTCACTCAGACATGGAGAAATTTATCAAGCAGTACAGTGAGGAATCAATGAAGCGCTACGTGAGTGAATTACAAGCGCATGCAGCCGCCCAACAAAACGGAGGCGGTAACAGTGAATCGTCTGAGAATCGACCAGAACATGGAAAACCAGAAATACCCTTAGATCTCAGCAAACCAGTCGATCTGTCACGGCCCGGATCAGATGCCGATGAACGGTCTGACACCGCGTCCGAGACTATGGAGTTTTACGAGGAAGACGAACCAACTTCACCACTTCCTGGTCAGCAATCAGTGCGGCAACCTGGCAAGCGATATCGTACTCAAATGTCATCTTTACAAGTTAAGATAATGAAATCATTATTCAGTGACTACAAAACTCCGACTATGGCTGAGTGTGAGGCACTTGGGCGCGAAATCGGTTTGCCTAAACGTGTAGTGCAAGTTTGGTTTCAAAACGCACGTGCCAAAGAAAAGAAAGCGCGCCTAGCCGCCGGACTGGTGGAAGTGTCAGATGCACCGCCCCCGGAGGAGTGTCGAGTGTGTGACTTTAAGTACAGTCACAAGTACTCAGTGCAAGACCACGTGTTTACGCGTAGCCATATCGCGGCTGTGCGTGCGCGGCTGGAGACTGGCACAAGCGCCGGTGAGGACAGTGCGCTCGCTCTCATGCAGATGGCAGCGCGCCTCGAGGGCGGCATCGGCGGTGATCTACACAACGCGTTCCTGCGGCCGCAACTCGCTGGAAACGGTGAGTGTACAACTTGA
Protein Sequence: MLVLQQNVKHMQTLSALHHRQQSHQQLESLLHFHGGDAPPPNPEAALADMAYNQALMIQLMTGGPGPSPPELGAHLDVGLNPEAMEPPPEPADPEPERTFHCCICNCFSTDSLEALGHHLAQDRTKIREQEILALVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKFCGGVGTGGASVGGVQVRCCACDYYTNSAHKLQLHAAGARHEAAALLLRHLRECASRIPRERPRVYRCALCGFGGPHRLPLLQHVRSVKHLQMEQIHQLQRRSEGKDPTPDVAELFQVIPQPTELPSPYDQQENDNKEPIDQKPELTQEQKMMRFLEQHQQQQQQQQVQQQSQQAASEREEERETPGPHACPYCNFSCTGETRLHAHVTSVHSDSARQFICPLCQDGFKERSALERHVMQIHSVNSEGLQRLLLLVDQSHWLNGGSQSQRDESRQGEDEREISSPRSEGSADGEMERCSTCNRTFRNVDELCQHQNETGHLELKQTPQGPGYVCWKKGCNRYFDAAHALQNHFREAHARNSIANMSVSEKHVYKYRCNQCSLAFKTVEKLQLHSQYHVIRDATKCVLCGRSFRSVLALQKHVDTSHSELSEEELSAFKRSLASNPLLQTGQGTALDAATAELLRKEALRTPEDDMADLEDRDSSATVADESGHNDAENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLTYPMEKYLDPNRPFKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNPPVSPGAGSAPSNLTLTPKSTSSEEDDRKRYKCNICKVAYTQGSTLDIHMRSVLHQTRAGKLQELAAAGHVDLTRPLVEQPDRNDPAKILQDVLSPKNTSPSSTSSGGPRSSPPARPGSPRSPRAGSAACERCHASFPTGELLDAHRATSCPFGDARAHSPLGEAETAALDEMVAKGNPPKRNSQMYKQLLETFGFDLVMQYNENQRRKMQEEREMVRVPSPPPPPPEEKPPDGETKSTCQHCNKEFSSVFVLKTHCEEVHKDKVPLEFLEQFAEQFKSEYERKSGAPNSPRAASPAPQGDRSPSPRGDNNGNFNENGSAPGDAQAGALLAAQVQEMQAALNMIQLQQQLGQLHPMVAQMLSLGLPLGLNVGALAAMNLQPPLVPLMLPPPPFDTMPFAHDAQLKQQQLLQQQQQANAAAGQKRARTRITDEQLKILRAHFDINNSPSDEAIAKMAQQSGLATKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVTTLDSSASSDEGKPPPEKKAKIEENSIIMQQEVKSEPHDEPTIEEKYHSYDDRHQEDKSFIFPHAPSQSPAPISQINDHHQNKSRPQTPTHMSLNSLIQSQLDSIPATSIPQPPHPSMLPPKLNPNFTSPNSAPPNVLPLTPNRSLSPGRGPADFGLSGGNSNGSNSSGSSGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLGLSPRVIVVWFQNARQKARKVYENQPAADPPASATDDANRFQRTPGLNYQCKKCQLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQVAATLSSEDSNSSNVEHHTPHVPVSPAPPRTPTPAAPNYPASPAPPTPITPVTPLSHTAPREEKDGNFQCDKCNLVFPRFDLWREHQLVHIMNPNLFPTYPPDSPFGILQQHAQLQQLNASLGGDEARHPLVAALNQQVVKRKFDEFEEIDTGEQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINVDALPDEELSTESTPSFGSQQSDRQQNFSQAGAPMLPPIFPPFHSDMEKFIKQYSEESMKRYVSELQAHAAAQQNGGGNSESSENRPEHGKPEIPLDLSKPVDLSRPGSDADERSDTASETMEFYEEDEPTSPLPGQQSVRQPGKRYRTQMSSLQVKIMKSLFSDYKTPTMAECEALGREIGLPKRVVQVWFQNARAKEKKARLAAGLVEVSDAPPPEECRVCDFKYSHKYSVQDHVFTRSHIAAVRARLETGTSAGEDSALALMQMAARLEGGIGGDLHNAFLRPQLAGNGECTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00706766;
90% Identity: iTF_00706766;
80% Identity: iTF_00706766;