Basic Information

Insect: Euplagia quadripunctaria
Gene Symbol: Zfa
Assembly: GCA_963859945.1
Location: OY982584.1:3794515-3813783[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0025 0.25 12.8 1.6 1 23 262 284 262 284 0.99

2 11 0.018 1.8 10.1 0.5 1 23 291 313 291 313 0.98

3 11 2.6 2.6e+02 3.3 2.0 1 10 317 326 317 340 0.73

4 11 9.5e-05 0.0095 17.3 2.4 1 20 347 366 347 368 0.96

5 11 0.0026 0.26 12.8 0.1 2 23 377 399 376 399 0.95

6 11 3.8e-05 0.0038 18.5 0.9 2 23 413 434 411 434 0.94

7 11 0.00015 0.015 16.7 0.3 1 22 440 461 440 465 0.94

8 11 5.9e-05 0.0059 17.9 2.5 2 23 474 496 473 496 0.96

9 11 2e-05 0.002 19.4 0.4 1 23 502 525 502 525 0.97

10 11 4.3e-06 0.00043 21.5 0.3 1 23 534 556 534 556 0.98

11 11 0.019 1.9 10.1 0.3 1 19 562 580 562 585 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0025	0.25	12.8	1.6	1	23	262	284	262	284	0.99
2	11	0.018	1.8	10.1	0.5	1	23	291	313	291	313	0.98
3	11	2.6	2.6e+02	3.3	2.0	1	10	317	326	317	340	0.73
4	11	9.5e-05	0.0095	17.3	2.4	1	20	347	366	347	368	0.96
5	11	0.0026	0.26	12.8	0.1	2	23	377	399	376	399	0.95
6	11	3.8e-05	0.0038	18.5	0.9	2	23	413	434	411	434	0.94
7	11	0.00015	0.015	16.7	0.3	1	22	440	461	440	465	0.94
8	11	5.9e-05	0.0059	17.9	2.5	2	23	474	496	473	496	0.96
9	11	2e-05	0.002	19.4	0.4	1	23	502	525	502	525	0.97
10	11	4.3e-06	0.00043	21.5	0.3	1	23	534	556	534	556	0.98
11	11	0.019	1.9	10.1	0.3	1	19	562	580	562	585	0.89

Sequence Information

Coding Sequence: ATGAGTGACTGCACTACATTTAATAATGAGGACAAGGAGGCCAAGCCTGATAGTCCAAAGGAGTATTGTTTTGGATGTCTGTGTGATAACAATGAAAGACAAATACACAACCACACATTTGTTTGTGGTCCTCTTAAGGAACTATTTCAGATGCAGAGTATGTGCCTGTGTTATTTATGCAAACGGATTGCCCAACACACAGAATTGTTCATACAGAATGTACAAAGCAATCAGATTTTATTGGagaacttttctaatgcaACAATGGATGAAACATTAACATCAGTAAGATTACAAACACAACCTCTAGTCAGTCTAAAACATGTCTCACATAATGTTATAGAACTGATAGAGAATGAAAGTAATAGTTTTGAGGAGTCCTTCTCTGTAGTGACCAATATAAAAGAGAAAGTAGATGTTAAAGTCAAGATTGAGATGAAAGAAGAGACCGAGTTGTTAGATAATATAGAAGCTGAGTTCATAAATCAAGATGATGAATTCCCTGAGATGTATCTCAAAGAAGAGGACGAATTTCCTCTGAACACATTGCTTAAAGAAGAAATAGAGATTGGAAATTTTGACaacttagatcttttaaatgtAAGCtcaacaaaaaagaagaaagtgaAGAAAAAGGACATTAACAGAGAAGGTGGAAAAAAGTCTAGAAAAGTAATACAAGTTACAGAAATACCTGAAGTAAAAATGATATACATAACAAGGAAACAGTGTATGGAGGAGCGGGCTAGGGTGTCAAAAGACCAGAAGTATTTAGCCTGCGTGTACAAATGCACTGACTGCATCAAAGGCTTTACTTTCAAAGGCAGCTATGACACACACATGGAGAAACATAATCAAagCAATGGTGATTACGAGTGTGACGTTTGCAAACAGAGAATGGATACAGATGATAAACTAGTCAGCCATATGAGATATCATTTAATtcgATACAAATGCCCAGTATGCGGCCTAACACGGAACTGCCGAAAGACAATCAAGGATCACTACTCCGCATATCACCTTGGAGGCGATTACCAGTACAAGTGTCCACAGTGTGTGAAGACATTCAAGCGCCAGTTGTCACTCCGCAAGCACGTGCTGTGCGTGCACGCGCGCCGCGAGCGCGTGCAGTGCGCGTACTGTGCGCGCACGTACGTCGACAAGGCCGTGCTCAAGTCACATATGATGCTAAAACATTCCAAAGAGGTGTCAGCAGTAGAAGTTTGTAAGAGATGTGTGTGTGCTGAATGTGGGATGGGGTTCAAAACTCCTTCTCAACTCCGCAACCACAGTATCAAGCACTCCGACACACGTGAATATTACTGCGTGGAGTGCGACAAGAGCTTTAAATCAGAAAGTATATTGAAAACTCATTTGAAGACTGCCGCCATCCACGTCAACTATAAAGAATTACCccTATCCTGTTTACACTGTGAAAAACGTTTTTCGAATCGCCGAGATGTCGAACGGCACATGAATCGGATCCATCTAAATGTCAAACCCTACAGATGTGATAGATGTGATAAgGCTTACGTGAACTCCTGGGGACTAAAGGACCACCAGCGCTACATTCACGAAGGGTACAAAAGGCCACTGCAGTTTCCGTGCCCTATGTGTGACAAAGTTTttgatCGTAATCAGATCCTCAAAAGCCACATACGTACGCACACAGGAGAGCGTCCGTACCAATGTAGCAAATGTCCGGCGCAGTTCAGTCAGGCCAGCATCCTTCGAACACACGATCGACTCGTCCATCTCAAACTGACCAGGGACGGTAGACCGAAGAGTGGTGGTGTAAAATAG
Protein Sequence: MSDCTTFNNEDKEAKPDSPKEYCFGCLCDNNERQIHNHTFVCGPLKELFQMQSMCLCYLCKRIAQHTELFIQNVQSNQILLENFSNATMDETLTSVRLQTQPLVSLKHVSHNVIELIENESNSFEESFSVVTNIKEKVDVKVKIEMKEETELLDNIEAEFINQDDEFPEMYLKEEDEFPLNTLLKEEIEIGNFDNLDLLNVSSTKKKKVKKKDINREGGKKSRKVIQVTEIPEVKMIYITRKQCMEERARVSKDQKYLACVYKCTDCIKGFTFKGSYDTHMEKHNQSNGDYECDVCKQRMDTDDKLVSHMRYHLIRYKCPVCGLTRNCRKTIKDHYSAYHLGGDYQYKCPQCVKTFKRQLSLRKHVLCVHARRERVQCAYCARTYVDKAVLKSHMMLKHSKEVSAVEVCKRCVCAECGMGFKTPSQLRNHSIKHSDTREYYCVECDKSFKSESILKTHLKTAAIHVNYKELPLSCLHCEKRFSNRRDVERHMNRIHLNVKPYRCDRCDKAYVNSWGLKDHQRYIHEGYKRPLQFPCPMCDKVFDRNQILKSHIRTHTGERPYQCSKCPAQFSQASILRTHDRLVHLKLTRDGRPKSGGVK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00441809;
90% Identity: -
80% Identity: -