Basic Information

Insect: Eupithecia vulgata
Gene Symbol: ZEB2_1
Assembly: GCA_946478135.1
Location: CAMLCK010000012.1:885835-897418[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.003 0.23 12.7 2.7 1 23 20 43 20 43 0.98

2 9 3.2 2.4e+02 3.2 5.0 1 23 50 72 50 72 0.84

3 9 0.001 0.078 14.1 0.6 1 23 103 126 103 126 0.95

4 9 2.8e-05 0.0021 19.1 0.3 2 23 131 153 130 153 0.96

5 9 1.1 80 4.7 0.5 3 21 187 205 186 210 0.90

6 9 5e-06 0.00037 21.4 1.2 1 23 218 241 218 241 0.96

7 9 0.0055 0.41 11.9 4.5 1 23 248 271 248 271 0.97

8 9 1e-06 7.7e-05 23.6 1.0 3 23 282 302 281 302 0.98

9 9 1.5e-05 0.0011 19.9 0.4 1 23 308 331 308 331 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.003	0.23	12.7	2.7	1	23	20	43	20	43	0.98
2	9	3.2	2.4e+02	3.2	5.0	1	23	50	72	50	72	0.84
3	9	0.001	0.078	14.1	0.6	1	23	103	126	103	126	0.95
4	9	2.8e-05	0.0021	19.1	0.3	2	23	131	153	130	153	0.96
5	9	1.1	80	4.7	0.5	3	21	187	205	186	210	0.90
6	9	5e-06	0.00037	21.4	1.2	1	23	218	241	218	241	0.96
7	9	0.0055	0.41	11.9	4.5	1	23	248	271	248	271	0.97
8	9	1e-06	7.7e-05	23.6	1.0	3	23	282	302	281	302	0.98
9	9	1.5e-05	0.0011	19.9	0.4	1	23	308	331	308	331	0.96

Sequence Information

Coding Sequence: ATGTTGGAGAGAAGACAGAAGGAGAAAGAGAATAAGGTTTACAAAGTTCAGTGCAAGTTTAGATGTGAACATTGCTTACTTGGGTTTATTGATGAGGCGTGTTTTGAGAAGCATATGGAGACGAGGCATACAGAGATAGGAGGTAATTTCGAATGCCACATATGCAAGCTGAGATTCATGAAATTCAACAACCATAAAGAACACACCGCCAACCACTACAAGAAGTACGTGTGTTCGTGCGACTTCTCCGGCCACAGTCTGTCGGAGATGGCGGAGCACGACGCTAAAGAGCACGGCTTGAAGAGGTTCCATTGCGGAGTCTGCAGGGAGGCTTTCTCTTCCCGCGGCGGCCTCAAGTATCACCGCGCGGTGTCGCACGTCAGTCCAGTGAAATGCGACATCTGTAATAAGATATTCAAGGCGCAGAAGTACCTCACTGTACACATCGAGAAGGTGCACAGCACCAAACCAATAGAAGCGTGTGTGGTGTGCGGCGAGCGACGGCGACAGATGGCAGTGCATATGCTCAAACATCAGCCCAAGCCGGAAGCGGCGTACTGCGCGGAGTGTGACCTTCACTTCGCCTCGATCCCGGTCTACAAAAACCACCTCAAGTACTCCTCCAAGCATCGCCCACCCGAGTCGCTCAAGTTTCCCTGTCCACACTGTGAATACAAGTTTGTGAACTCCACTTCTCTTAACAAACACCTGATTGTGCGGCATTTTAAGGAGCAACGGCCTTTTAAATGCGATAAATGTGATAAGCGATTCGAGGCGTTATGCCGACTCCGCACACACACGAGGTATGAGCACGACGGTGTAGAGAAGCCGAAAAACAAGATCTGTCATATATGCGGCCGCGGGTTCAGAactaagTTCATGCTGGCCAACCACATCCGCGTTCACACGGGAGAGAAGCCCTTCCGCTGTGGATTGTGCTCCGCCGCCTTCAGCCAGAAGAGCTCGCTCACTACGCACACACGAGGCGTGCACTTGAAGATCAAACCACGGCCTAACCGATAG
Protein Sequence: MLERRQKEKENKVYKVQCKFRCEHCLLGFIDEACFEKHMETRHTEIGGNFECHICKLRFMKFNNHKEHTANHYKKYVCSCDFSGHSLSEMAEHDAKEHGLKRFHCGVCREAFSSRGGLKYHRAVSHVSPVKCDICNKIFKAQKYLTVHIEKVHSTKPIEACVVCGERRRQMAVHMLKHQPKPEAAYCAECDLHFASIPVYKNHLKYSSKHRPPESLKFPCPHCEYKFVNSTSLNKHLIVRHFKEQRPFKCDKCDKRFEALCRLRTHTRYEHDGVEKPKNKICHICGRGFRTKFMLANHIRVHTGEKPFRCGLCSAAFSQKSSLTTHTRGVHLKIKPRPNR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00321906;
90% Identity: iTF_00702364;
80% Identity: -