Basic Information

Insect: Eupithecia vulgata
Gene Symbol: ZNF521
Assembly: GCA_946478135.1
Location: CAMLCK010000125.1:1414409-1427836[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 28 0.18 13 7.1 2.0 1 23 238 261 238 261 0.96

2 28 0.22 17 6.8 0.1 3 23 286 307 284 307 0.95

3 28 0.00025 0.019 16.1 1.6 2 23 330 351 329 351 0.96

4 28 0.1 7.8 7.8 1.7 1 23 355 377 355 377 0.85

5 28 0.0017 0.13 13.5 1.2 1 23 381 404 381 404 0.97

6 28 0.027 2.1 9.7 1.5 1 23 410 433 410 433 0.96

7 28 0.013 0.98 10.7 0.2 1 13 440 452 440 455 0.87

8 28 0.075 5.6 8.3 3.1 1 23 504 526 504 526 0.92

9 28 0.0087 0.65 11.2 3.1 1 23 594 616 594 616 0.97

10 28 0.58 44 5.5 0.3 1 10 620 629 620 642 0.76

11 28 0.024 1.8 9.8 2.1 2 23 647 669 646 669 0.96

12 28 0.17 13 7.2 1.0 2 23 674 696 673 696 0.95

13 28 0.076 5.7 8.3 3.1 1 23 747 769 747 769 0.96

14 28 6.4 4.8e+02 2.2 0.0 3 23 799 820 797 820 0.90

15 28 0.065 4.8 8.5 0.7 2 23 841 863 840 863 0.94

16 28 0.0019 0.14 13.3 3.2 3 23 870 891 869 891 0.97

17 28 0.01 0.76 11.0 1.0 1 23 896 919 896 919 0.94

18 28 0.22 16 6.8 0.1 2 23 922 944 921 944 0.93

19 28 0.036 2.7 9.3 0.7 2 22 951 971 950 971 0.93

20 28 0.0032 0.24 12.6 0.4 1 23 1028 1051 1028 1051 0.95

21 28 1 77 4.7 0.1 3 23 1080 1101 1078 1101 0.92

22 28 0.079 5.9 8.2 0.2 3 23 1125 1147 1123 1147 0.95

23 28 0.00095 0.071 14.3 0.4 3 20 1154 1171 1152 1175 0.90

24 28 0.59 44 5.5 0.2 1 23 1180 1203 1180 1203 0.95

25 28 0.00089 0.067 14.3 0.3 2 23 1209 1231 1208 1231 0.93

26 28 0.00071 0.053 14.7 4.5 1 23 1235 1258 1235 1258 0.97

27 28 0.00059 0.044 14.9 0.6 2 23 1265 1286 1264 1286 0.96

28 28 0.0094 0.7 11.1 2.3 1 23 1292 1314 1292 1314 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	28	0.18	13	7.1	2.0	1	23	238	261	238	261	0.96
2	28	0.22	17	6.8	0.1	3	23	286	307	284	307	0.95
3	28	0.00025	0.019	16.1	1.6	2	23	330	351	329	351	0.96
4	28	0.1	7.8	7.8	1.7	1	23	355	377	355	377	0.85
5	28	0.0017	0.13	13.5	1.2	1	23	381	404	381	404	0.97
6	28	0.027	2.1	9.7	1.5	1	23	410	433	410	433	0.96
7	28	0.013	0.98	10.7	0.2	1	13	440	452	440	455	0.87
8	28	0.075	5.6	8.3	3.1	1	23	504	526	504	526	0.92
9	28	0.0087	0.65	11.2	3.1	1	23	594	616	594	616	0.97
10	28	0.58	44	5.5	0.3	1	10	620	629	620	642	0.76
11	28	0.024	1.8	9.8	2.1	2	23	647	669	646	669	0.96
12	28	0.17	13	7.2	1.0	2	23	674	696	673	696	0.95
13	28	0.076	5.7	8.3	3.1	1	23	747	769	747	769	0.96
14	28	6.4	4.8e+02	2.2	0.0	3	23	799	820	797	820	0.90
15	28	0.065	4.8	8.5	0.7	2	23	841	863	840	863	0.94
16	28	0.0019	0.14	13.3	3.2	3	23	870	891	869	891	0.97
17	28	0.01	0.76	11.0	1.0	1	23	896	919	896	919	0.94
18	28	0.22	16	6.8	0.1	2	23	922	944	921	944	0.93
19	28	0.036	2.7	9.3	0.7	2	22	951	971	950	971	0.93
20	28	0.0032	0.24	12.6	0.4	1	23	1028	1051	1028	1051	0.95
21	28	1	77	4.7	0.1	3	23	1080	1101	1078	1101	0.92
22	28	0.079	5.9	8.2	0.2	3	23	1125	1147	1123	1147	0.95
23	28	0.00095	0.071	14.3	0.4	3	20	1154	1171	1152	1175	0.90
24	28	0.59	44	5.5	0.2	1	23	1180	1203	1180	1203	0.95
25	28	0.00089	0.067	14.3	0.3	2	23	1209	1231	1208	1231	0.93
26	28	0.00071	0.053	14.7	4.5	1	23	1235	1258	1235	1258	0.97
27	28	0.00059	0.044	14.9	0.6	2	23	1265	1286	1264	1286	0.96
28	28	0.0094	0.7	11.1	2.3	1	23	1292	1314	1292	1314	0.97

Sequence Information

Coding Sequence: ATGGATTACGACGTAGCTGTGAAGGAGAGCCCCGGCCTCTGCCGGTGTTGTCTCTCGGAGGGCTGCTACAAGGATCTCGGCTCTGAATATTCGTGGATGAATGACACCGAAGTATACGCTGATATGCTGCTAGACTGCTTTGATATTGGCATCACTCAACACACCGATGGCCCCAACGGGCCCAAGCGCCTCATCTGTGAGGTATGCATCACCCGTCTCCGAGACGCCTGCAACTTCAAGAAGCAAGTTGTGGACTCCGAGAAGAAGTTCATAGACATGCTCGGACGAGGGGAGTTCAGGGTGATGGAGAGGCAGTCAGTAATGCTGCCGATCTACACCAGTGCAGTTCCAATGAAAGCGGAGGCGATGGAGGAGGTTAATCTGAACGATGACTTCGAAGACACTAACGTCGAGTACTTGGAGGATGTTGACTTTATTGAGGAAGATGATACAGTAAAAGCGGAGAGCCCAGAACCTACTCCATCATCCTCAACATCAGCCTCAAAGCGAGGCAGGCCTCGTAAAGCAGAAGTCGAGCCTCCAGAAAAGAAACCCAAACTCAAGAATAAGGCCAAGATCGCTAAAGGTGGAAACGCCCCCGCGGTCCCCAGCCACGCATCGAAAATACATCGTAACAGACTTCTTAAATCCAACACTGTCAATATACTAGAACACTCCACCGTTCTTCCTTTTAAATACCAGGGAAAATCGTACTTTTGCTTTTACTGCAACTCTCAAATCAGCACGTttcaaaaccttaaaaaacacGTAGAGACCGAACACCAAAAAACtccaaaaaaatctgttttcatCAAGAAAGGAGCTATCGTTAAAATTGATGTAGCATCTATAAACTGCAAGCTATGCAATGCGAAGCTAGAAAACCTGGAAGAGCTAGTCTCACATCTGAAAATAGCGCACAATAAACAGTTCTATGACGAGTTAGGCTACGGCGTTATGCCCTACAAACACTACCCCGCCAACTGCCAATGCGCTATTTGCGGCGAAACCTTCGACTACTATATAAAACTAAATCAACATATGAACAAACATTTCGGTAAACACGTCTGCGAAATTTGCGGAAAGAGTTTCTTGAACACGATCCGTTTAAAGACTCACTCCTTCTCACACGGAGCTAGTTACCCTTGCAGTTATTGTTCTGAAGCTTTCCGCACTTATTCGAAAAGAAAGAATCATTACGCAACAGCGCATAATCTTTCTAAAGAACATAAATGTCTTTATTGCTCGGAAACCTTTCCAAACTACGGTGCGAGGACCCTGCATTTAAGATACGTTCATAATATTGACACTCCGAACTATGATTGTCCGATTTGTGGTAAATCTTTTCGGTTGAACAGTGGCAATACTGGCTATCCCGTGCCCGAGCTGCCAGAAAAAGTCCGTAAGTCAAAACTGACTTCCACGAAACTCAACCGTATGAGAAATCATAACACGATAACCATCCTACAAAACAGTACAGCTATTCCTTTCAAATGGCATCGACAATTTTACCTCTGTTTCTACTGCCACAAACCTTTTTCCACCTTCAACGAGGTAAAAGAACACACAACCGATCATAATTCTGTAAACATTAAAGCCGCTGTCACGTTCTGCGCGAACGATAAAGCCAAAATCGATATAACCTCCTTTAAATGCAAAATTTGTGATCAAGATCTTTTAAACATAACCTCTTGCATGGACCACTTAAAGCAAACACACGGGAAAACCTTCGAAGACTCTGACATAGGTGTTATTCCTTACAAACACGAGATAAACTCTTTCGACTGTGGTATTTGCAATCAGAAATTCCACTACTTTGTAAAATTGAATCAGCACATGAATTCTCATTATGGGAATCACATTTGCGAGACTTGTGGGAAATCCTTTCTCAGCGCAGCGAGACGCAGACTGCATTCTCTCATCCATGCTAGCGATGTCCAATGCGAGCATTGCCCTGAGAAATTTAGATCTTTGTCTATGAAGAATTATCACGTAAATAAGACTCACCAATCTAACGTGAAATGTAGCTTTTGTTCTGAACAATTCGCTAGCTACAAGCAAAGAAAGGTGCATTTAAAGCTCGTTCATAATATAGGGTCGCTGCACGCTTGCCCGGTCTGCAGCCATGTAAAACCGCGAAAATACAAGGGTACGGGATCTTCTTCGATGCGCCGAAGGAAAAACCTCCAAATTATATTCAACAATACATCAATTATACCATTTAAATGGCGAGGGAAATATCTTTGCTTCTATTGCAGCAAGCATCTGCCGGAATACGATGATCTACGCAAACATACAAAATCTCACGGCGATTGCTCTATCCTAGATCATTCGCTGAAAGTTTTGAAAGGCGGAACAAACATGGAAATCAAAATTGACGTGTCAGATATAATTTGTGAATATTGCGGTGTAAAACAGCCTTCTGTTGATAATGTAATAGATCATTTGAAAATTATGCATGATATACATTATGATAGCGAGGTGGATATGGCTACAGAGGCGTACAGACTTGCTGATCTCAGCTGCTTGTCTTGCGaacaaaaatttacttacttCGGTTACTTGGTCTCGCATATGAACAACCAACACCCGAAAAACTGCATCCTCTGTGATAAATGCAACCAAAAATTCAATAAGAAGCGAGATCTCTTCTCGCATATGAAAAACTATCATAGAGAAGGTGGATATCAATGCGAGGTCTGTCCTCAAACGTTCAACTCTCTAAATATCCTGAGAAAACATAGAACGAACAGGCATTTCACTAGATGCAATATCTGCCAGCTGAGGTTACCTTCAGCGGCGTTGATACAAAAACATATGGACCTTGAGCATCCAGATGACGGCTCCTTGCAATGTGATAATTGCGCTAAAGAATTCCACACGAAAACAGGTCTTAGAATGCACGCGAGAAAATGCAAAATAGATTTCAAATACACTGTCAAAAAGGAAGATCTTACAATGGATCTTGATCAGAACTACGAAAATCCGCCAAAAAGACCGAGCGTCAAGCAAATCCGCGAAAATATAGTTATTGTCATCAATATGTCCACGGCAATCCCTTTCAACTTCTACCAGAACAAATTTAATTGCTTCTATTGCTCCAAAGACTTCCCGGATTCGGATTCTATGAGAGAACACACAATAATCGAACATCCAGTGTGTAACATCACAGAGAAATGTATCAAAAAATGCAGAGAGACCGTCACATGCGTTAAAATTGACATATCCACATTAGCCTGCAAACTCTGCTTCGAATCTATATCCGATTTAGATAAACTTCTCGACCATTTGATCCTGAAACACAACGCAAATTATGATAAAACGATAACAACATGCCTACAACCGTACAGACTTGTAAAAGACCACATGGCTTGCCCCAACTGTCCGACAGAAGTCTTCCGCTTCTTCGGAACCCTTCTAAAACATATGAACAAAGAACACACTAATAATCATATCATATGCGTTTATTGCGGTGAGACTTTTCGACGGGATCAAAACCTCCGCGTTCATATATGGAGACACCACCGCGATGGTAGATTCAAATGCGGTATCTGCGATGCCGACTGCGGTATACCATCACGACTTTACATGCATATGGCAAAAGAACATGGTGTTAAAGCATCAAAATGTCCTAAATGCCCCGAAAGTTTTGAGACGCAATACCTTCGCCAAAAGCATCTTATCGAAGTTCATAATTCCGGGCACAAATGCACTTTCTGCGGGAAGCTTTTCACCAGGGAGTCTTTCATGAGAGATCATATAAGACGCACGCATTTAAAGGAAAAGAATGTTGAGTGTAATATATGTAGTATgaagttttttaataatattctatTGAGGAGGCACATGGTTAAACATAGTGGAGAAAAGAATTTCCATTGTGATGTGTGCGGGGAGAGGTTCTTCTGGAGGAAGAGTCTTAGGACGCATATGGCACGGCATAATAAACAAATCCAGCCGGTTATGTAG
Protein Sequence: MDYDVAVKESPGLCRCCLSEGCYKDLGSEYSWMNDTEVYADMLLDCFDIGITQHTDGPNGPKRLICEVCITRLRDACNFKKQVVDSEKKFIDMLGRGEFRVMERQSVMLPIYTSAVPMKAEAMEEVNLNDDFEDTNVEYLEDVDFIEEDDTVKAESPEPTPSSSTSASKRGRPRKAEVEPPEKKPKLKNKAKIAKGGNAPAVPSHASKIHRNRLLKSNTVNILEHSTVLPFKYQGKSYFCFYCNSQISTFQNLKKHVETEHQKTPKKSVFIKKGAIVKIDVASINCKLCNAKLENLEELVSHLKIAHNKQFYDELGYGVMPYKHYPANCQCAICGETFDYYIKLNQHMNKHFGKHVCEICGKSFLNTIRLKTHSFSHGASYPCSYCSEAFRTYSKRKNHYATAHNLSKEHKCLYCSETFPNYGARTLHLRYVHNIDTPNYDCPICGKSFRLNSGNTGYPVPELPEKVRKSKLTSTKLNRMRNHNTITILQNSTAIPFKWHRQFYLCFYCHKPFSTFNEVKEHTTDHNSVNIKAAVTFCANDKAKIDITSFKCKICDQDLLNITSCMDHLKQTHGKTFEDSDIGVIPYKHEINSFDCGICNQKFHYFVKLNQHMNSHYGNHICETCGKSFLSAARRRLHSLIHASDVQCEHCPEKFRSLSMKNYHVNKTHQSNVKCSFCSEQFASYKQRKVHLKLVHNIGSLHACPVCSHVKPRKYKGTGSSSMRRRKNLQIIFNNTSIIPFKWRGKYLCFYCSKHLPEYDDLRKHTKSHGDCSILDHSLKVLKGGTNMEIKIDVSDIICEYCGVKQPSVDNVIDHLKIMHDIHYDSEVDMATEAYRLADLSCLSCEQKFTYFGYLVSHMNNQHPKNCILCDKCNQKFNKKRDLFSHMKNYHREGGYQCEVCPQTFNSLNILRKHRTNRHFTRCNICQLRLPSAALIQKHMDLEHPDDGSLQCDNCAKEFHTKTGLRMHARKCKIDFKYTVKKEDLTMDLDQNYENPPKRPSVKQIRENIVIVINMSTAIPFNFYQNKFNCFYCSKDFPDSDSMREHTIIEHPVCNITEKCIKKCRETVTCVKIDISTLACKLCFESISDLDKLLDHLILKHNANYDKTITTCLQPYRLVKDHMACPNCPTEVFRFFGTLLKHMNKEHTNNHIICVYCGETFRRDQNLRVHIWRHHRDGRFKCGICDADCGIPSRLYMHMAKEHGVKASKCPKCPESFETQYLRQKHLIEVHNSGHKCTFCGKLFTRESFMRDHIRRTHLKEKNVECNICSMKFFNNILLRRHMVKHSGEKNFHCDVCGERFFWRKSLRTHMARHNKQIQPVM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00701297;
90% Identity: iTF_00699467;
80% Identity: -