Basic Information

Insect: Eupithecia vulgata
Gene Symbol: ZNF296
Assembly: GCA_946478135.1
Location: CAMLCK010000209.1:22841-24607[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.15 11 7.3 3.3 2 23 181 202 180 202 0.97

2 12 1.8e-05 0.0013 19.7 3.1 1 23 208 230 208 230 0.97

3 12 0.00092 0.069 14.3 0.1 3 23 263 283 262 283 0.98

4 12 1.5e-05 0.0011 19.9 2.0 1 23 289 312 289 312 0.97

5 12 3e-07 2.3e-05 25.3 3.4 1 23 320 342 320 342 0.99

6 12 5.9e-06 0.00044 21.2 0.3 1 23 348 370 348 370 0.98

7 12 9.2e-07 6.9e-05 23.7 0.3 1 23 376 398 376 398 0.97

8 12 0.00084 0.063 14.4 0.7 1 23 404 426 404 426 0.95

9 12 6.5e-07 4.9e-05 24.2 0.2 1 23 432 455 432 455 0.97

10 12 0.011 0.82 10.9 2.7 1 21 485 505 485 508 0.90

11 12 0.052 3.9 8.8 0.4 1 23 514 539 514 539 0.92

12 12 0.0094 0.7 11.1 2.4 1 23 545 568 545 568 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.15	11	7.3	3.3	2	23	181	202	180	202	0.97
2	12	1.8e-05	0.0013	19.7	3.1	1	23	208	230	208	230	0.97
3	12	0.00092	0.069	14.3	0.1	3	23	263	283	262	283	0.98
4	12	1.5e-05	0.0011	19.9	2.0	1	23	289	312	289	312	0.97
5	12	3e-07	2.3e-05	25.3	3.4	1	23	320	342	320	342	0.99
6	12	5.9e-06	0.00044	21.2	0.3	1	23	348	370	348	370	0.98
7	12	9.2e-07	6.9e-05	23.7	0.3	1	23	376	398	376	398	0.97
8	12	0.00084	0.063	14.4	0.7	1	23	404	426	404	426	0.95
9	12	6.5e-07	4.9e-05	24.2	0.2	1	23	432	455	432	455	0.97
10	12	0.011	0.82	10.9	2.7	1	21	485	505	485	508	0.90
11	12	0.052	3.9	8.8	0.4	1	23	514	539	514	539	0.92
12	12	0.0094	0.7	11.1	2.4	1	23	545	568	545	568	0.97

Sequence Information

Coding Sequence: ATGGAGTCCAAAATATGTCGCGTATGCCTCGACAGAACGGCCACAATATCTCTGTTCGACACAGTGGATGATGTCCAGTACCGGGACAAGGTGAAGAAGTGTGTGGGAGTGAGTATCGAGGAGGGCGATGGGTTGCCCGACGCCATCTGCGACAGTTGCGCCGTCGAGCTCGCCGCCAGCTATGAGTTCGCGCTCAAATGTGAGGCCTCGGACCGCGCGCTGCGCTGTCTCGACCTCCTGCACTCCTCCGGTCTCAAGGACGAATACATCAAAGCTGAGGTCAAGCTAGAAGAACCGATATATCAGACCCCTATTGATATTATACAAGAATTAACAAATCAAAATCTTGATGACATGAACAGTtatgataattatgattattttgaaagcttATCCGATAATAAAGACAACTTGGATGAAGCTCTTATGAACCTAAAGAATGATATACCTAAGAAAAAGAGGATATTGCAAGAAAAGTACAAGAAACCTCTACCAAACCATCTACGTAAGATTAAACACAGAGTTTACTCTGGCCCTATTCAGTGCATGACCTGTGGAAGAGTACTTAAGTGTCATTCTGCTTACGAGCTGCACATGCGCAGGCACACCAAAGAGAAACCATTCATTTGTGATCTCTGCTACAAAAGCTTCAGATCCAAGAGTAGTATGAAGAGACACATCTACAAGCATTATGGAGTTGATGAAAATGAACTCCGAAAACAAAAACCACTGCCTGATTGGGATGGAAGGAAGAAAGGGAATAAGGCCTGCACAACCCCCGTTCTGTGCGTTGTTTGTGGCCTTAAACTGAAGTCAGCCTCTGCCTTTGAAATCCACATGAGGAAACACACGGGAGATAAACCCTTCTCATGCACAGAATGCAGCAAAAGCTACTCTCTCAAAGGTTCTCTCAGAAGACATCAAGAAACATTTCACACTAAATTAAaaccattaaaatatgtttgCGAACACTGCGGAAAGAATTTCAGTCacaaaagtaatataataattcatCTACGAACACACACAGGAGAGAAGCCTTATGCGTGCCCGTATTGTGAGGAGAAGTTCGCTCAGATATCGTCGCTGATCCGTCACAAGCGCTCCCACACCGGGGAGCGGCCATTCAAGTGTGAGACTTGCGGGAAGGGCTTTTCAGACCGCAGTCTGGTACGCCGGCACATGGCGGCTCACAGCGACGCACGCAACTTCGTCTGCCACATATGCAGCAAGGGACTGAAGACGAGACAAGCTCTGAAAGTCCATGTGGACCTTCACAACAGTTCCGGCAAGTACGCCTGCGCGGACTGCGGCGTCACATTCACGGTGAAGGGCAACCTCACCTCGCACATGCGCCGCCAGCACTCGGCGCGCTCCGGGCTCTGCGCGCTCTGCGACAAGACTGTCCCCGACCTGGCGGCCCATGTGCGCTGGCACAGCGGGGAGAAACCACACGTCTGTAAGATCTGTAACCAGGGGTTCATGTCGAAGCGTGGATTGTCGCACCACATCGGGTTCAAGCACCGCGATTCCACTAAGTTCAAGTGCACGACGGGGCAATGCGACCGCGCATTCCCTACGATTTCGATGCTTGAGTTCCACGTGCTAAAGACCCACCTCGATCGTACGCCCTACATCTGCTCGCATTGTGCGCGGGGTTTCCTGCGGCCCTGCGACCTCTCCCGACATCTGCGCGTCAGCCACATGGACAATACGCAGATCAAGTCGCAGTTCATCAAAACTGTGCAGATTTCTGACCCGGCCTAA
Protein Sequence: MESKICRVCLDRTATISLFDTVDDVQYRDKVKKCVGVSIEEGDGLPDAICDSCAVELAASYEFALKCEASDRALRCLDLLHSSGLKDEYIKAEVKLEEPIYQTPIDIIQELTNQNLDDMNSYDNYDYFESLSDNKDNLDEALMNLKNDIPKKKRILQEKYKKPLPNHLRKIKHRVYSGPIQCMTCGRVLKCHSAYELHMRRHTKEKPFICDLCYKSFRSKSSMKRHIYKHYGVDENELRKQKPLPDWDGRKKGNKACTTPVLCVVCGLKLKSASAFEIHMRKHTGDKPFSCTECSKSYSLKGSLRRHQETFHTKLKPLKYVCEHCGKNFSHKSNIIIHLRTHTGEKPYACPYCEEKFAQISSLIRHKRSHTGERPFKCETCGKGFSDRSLVRRHMAAHSDARNFVCHICSKGLKTRQALKVHVDLHNSSGKYACADCGVTFTVKGNLTSHMRRQHSARSGLCALCDKTVPDLAAHVRWHSGEKPHVCKICNQGFMSKRGLSHHIGFKHRDSTKFKCTTGQCDRAFPTISMLEFHVLKTHLDRTPYICSHCARGFLRPCDLSRHLRVSHMDNTQIKSQFIKTVQISDPA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00703252;
90% Identity: iTF_00701311;
80% Identity: -