Esub018376.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Eupithecia subumbrata
Gene Symbol
-
Assembly
GCA_949316285.1
Location
OX438643.1:21717274-21731613[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00041 0.035 15.5 3.4 1 23 236 258 236 258 0.98
2 11 8e-05 0.0068 17.7 6.8 1 23 264 286 264 286 0.97
3 11 0.002 0.17 13.3 7.0 1 23 292 314 292 314 0.99
4 11 0.00077 0.066 14.6 1.5 1 23 320 342 320 342 0.97
5 11 1.3e-05 0.0011 20.2 1.0 1 23 348 370 348 370 0.96
6 11 7.7e-06 0.00065 20.9 0.0 1 23 376 398 376 398 0.98
7 11 8.4e-05 0.0072 17.6 0.4 1 23 403 425 403 425 0.96
8 11 0.0062 0.53 11.8 2.1 3 21 433 451 432 455 0.88
9 11 4.1e-05 0.0035 18.6 0.4 1 23 577 599 577 599 0.97
10 11 0.00012 0.01 17.2 2.0 1 23 667 689 667 689 0.96
11 11 4.4e-05 0.0038 18.5 4.3 1 23 699 721 699 721 0.97

Sequence Information

Coding Sequence
ATGTGTATGCCAACACCTAACAATGTGTCTGGGTTTGGTGGCTATTCCTGGTTTAGCAGTTCAAATGACCTTACAAAGGGTGAGGTTGATACTCCAAGCACCCTCAGCTATACACTTGGGAGCAATGTCTCACCAGAAACCACCTTGACTGTAATGTCCCACAAAACACCGCAAGTCCAAGATAAAATTGGCACTGTATCCGTAGCGGTCTCAAATACAGGAGCGCAAGTCACCAGAGTGGTGACCACGGGCACACCTGTCACTGCCAGGCGGGCTATGTTTGTGCTGAATGACTCTCTACCTATGAACAGAGTAACACCACAGAATCAGACTGCGACTATACATGCTGCAAACCTAGCATCAAAGTCCTTCATGTCTCCTATCGGTCCCATACAACTAACAACGGAAGAATGTAATGAGATCCTCATGAAAAGAGCTCTGCAAGCCCAAGGCATTGCCACACCCGTCATAGACGCCTCTCAACTCAACCACACACTACTGAATGGCAGCTTGAAGAGTCTTGCAGAGAATACTCAACAACAGGAGACCATACAGACTACAACAGTGCAGCATCACCTATTACATACTAAGCAGGAACCTGGAACAACTAATAATTCACCAAAAGCGGTATATTCACAGACAGAGCTGCTTTCAACCAACACGGTGATGACGGCGCAGGCGCCGGCCGCCGTCAAAGAACGGCCGTATTCTTGCGACGAGTGCGGGAAGAGCTTTCTGCTGAAGCATCATCTAACTACCCACGCGAGAGTCCATACTGGTGAAAGGCCACATGTTTGCGGACACTGCGGCAAAGCCTTCGCTCGCAAGCACTGCCTCAACACACACATGCTTCTGCATTCCTCCGATCGTCCGTACAAGTGCCACGAGTGTAAGATGGCGTTTACACTGAAGCATCATCTTGTGACGCATTCGAGGGTACACAGCCGGGACCGTCCATACATATGCCAGGAGTGCGGGCGAGGGTTCCCTCTCAACCGACACCTCGTCACGCATCGGAAGTTCCACGCGGGGGAGAGGCCTTATATCTGTAACGATTGCGGCGAGAGCTTTGCACAAAAGGAGCACCTGGTAATGCACAGTCGTTTCCACGGTTCCCTCTCTCCATTCGTGTGCCCCGACTGCGGGGCTGCCTTCGCCAGGAAGTTCCAGCTCGTGAACCACGGTCGGGTCCACGGGAGGGTGCCGCACGCGTGTCCTGTTTGCGGTAAAGAGTTCCTGCAGAAACGGACATTGGTCGCACATATGaaAATACACACAGGAGATGGCGTCGTCGCCTGCCTAGAATGCGGCGAGGCCTTTAAGTCTAAAACCGATCTGACACAACACTGCAAAACCACGCGACATTGCTCCTACGGCACTCCCACTACCATACAAATAGAAGTGCCGCAGCAACAGAATCAGCAACAACAGCAACAGCAGCAACAACAACAGCAGCAGCAGCAACAACAGCAGCAGcagcaacaacaacaacaacagcaGCAGCAACAACAGCAGCAACAAACAACAGTGATAAAGTCAGATGATTTCAATATCAAACCGCAAATTGTACAGGTATATTGCAAGCCGCAAGTGCAACAGCAACTGCAACAGATTTCGCAACAGCAACAGCAGCAACAAACGACGGTAATAAAGTCTGATGATTTCAAACCGCAGATTGTCCAGattGGTGCTGATGGCCAGATACTAACTGATAAAGCGACACCAGCGTATGCCTGTCCCGAGTGCGGATCGTGTTTTAATACAAAGGAGGCTCTTTCCCTACATGTACGCCTACACGCGGGCGACCGGACGTGCGTTACTGATCTATGCGCGCTCACAGCGGCGCTGCAGCCCGGCGGACTGGTCGCCGCCGCAGCTGCACACAACGCCAACAATGCACAACATCAACACGTCCAAATCATATCGTCAAGTCCAAGTAACGCAGTTCACACGCAAGTAATAGCGACGAATCATCACGCAGCGCCTCGACCGAAACTGCATTTCTGCAGCGAATGCGGGAAAGGATTTGCGGCGAAACATGGATTACTAGCACATCAAAGGAGGCATCCCGACGGCAGCTGTACGCTTCGAACGCACGTTTGCGACCAGTGCGGAAAGGCATTCTTCCAGAAGAATCACTTGATGCTGCATCAGCGGCAGCATATGGATTTGTCTAGGAATAACTCCCAACAACAACAGCAGcagcaacaacaacaacaacaacagcagcagcagcagcagcagcaacAACAACAGCAAGCGCAGCAACAAGCGGCCCAACAAGCAGCGCAGCAAGTCGTCCAACAAGTTCAACAACAAGTCCAACAAGTCCAGGTCCAACACCAACACCAACAGACCACGATGGAGATGGAGCAGGATCACCAACAACAGACGCATATTCAAGTGGTAAACCGTTCAGGCCAAGTGATcggcaatcaaataatagtggGCGGGCTAGGGCGGCGGCTAGTCACGCCCCACGTCATCGCGATGTCGCGCGATACCAAACACCTCACGCATAAACATCACACACAGAGACAGCATACTACCACCGGCGACGTCAAAGACCTCGGCCTAGTCCTATCAGCAGGCCGAGGGCAAGGCCTCATCAAGTACGAAATCTCAATCCCTCCTTCAAACTCGAACGTACAAGTGCAACAACTCGACTGA
Protein Sequence
MCMPTPNNVSGFGGYSWFSSSNDLTKGEVDTPSTLSYTLGSNVSPETTLTVMSHKTPQVQDKIGTVSVAVSNTGAQVTRVVTTGTPVTARRAMFVLNDSLPMNRVTPQNQTATIHAANLASKSFMSPIGPIQLTTEECNEILMKRALQAQGIATPVIDASQLNHTLLNGSLKSLAENTQQQETIQTTTVQHHLLHTKQEPGTTNNSPKAVYSQTELLSTNTVMTAQAPAAVKERPYSCDECGKSFLLKHHLTTHARVHTGERPHVCGHCGKAFARKHCLNTHMLLHSSDRPYKCHECKMAFTLKHHLVTHSRVHSRDRPYICQECGRGFPLNRHLVTHRKFHAGERPYICNDCGESFAQKEHLVMHSRFHGSLSPFVCPDCGAAFARKFQLVNHGRVHGRVPHACPVCGKEFLQKRTLVAHMKIHTGDGVVACLECGEAFKSKTDLTQHCKTTRHCSYGTPTTIQIEVPQQQNQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTVIKSDDFNIKPQIVQVYCKPQVQQQLQQISQQQQQQQTTVIKSDDFKPQIVQIGADGQILTDKATPAYACPECGSCFNTKEALSLHVRLHAGDRTCVTDLCALTAALQPGGLVAAAAAHNANNAQHQHVQIISSSPSNAVHTQVIATNHHAAPRPKLHFCSECGKGFAAKHGLLAHQRRHPDGSCTLRTHVCDQCGKAFFQKNHLMLHQRQHMDLSRNNSQQQQQQQQQQQQQQQQQQQQQQQQAQQQAAQQAAQQVVQQVQQQVQQVQVQHQHQQTTMEMEQDHQQQTHIQVVNRSGQVIGNQIIVGGLGRRLVTPHVIAMSRDTKHLTHKHHTQRQHTTTGDVKDLGLVLSAGRGQGLIKYEISIPPSNSNVQVQQLD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00697601;
90% Identity
iTF_00706277;
80% Identity
-