Basic Information

Gene Symbol
-
Assembly
GCA_963931895.1
Location
OZ007536.1:12498908-12500865[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 1.5e-05 0.0011 19.9 4.8 1 23 162 184 162 184 0.98
2 13 0.00015 0.011 16.8 0.2 1 23 190 213 190 213 0.96
3 13 5.4e-06 0.00039 21.3 2.4 2 23 219 241 219 241 0.96
4 13 1.7e-05 0.0012 19.8 3.1 2 23 247 268 246 268 0.97
5 13 3.1e-05 0.0022 18.9 0.1 1 23 274 296 274 296 0.98
6 13 2.3e-06 0.00016 22.5 1.9 1 23 302 324 302 324 0.96
7 13 8.3e-05 0.0059 17.6 2.5 1 23 330 352 330 352 0.94
8 13 0.0012 0.089 13.9 0.5 1 23 358 380 358 380 0.97
9 13 1.3e-05 0.0009 20.1 1.2 1 23 386 408 386 408 0.98
10 13 1.8e-06 0.00013 22.8 0.3 1 23 414 436 414 436 0.97
11 13 6.7e-06 0.00047 21.0 1.6 1 23 442 464 442 464 0.98
12 13 0.00025 0.018 16.1 4.4 1 23 470 492 470 492 0.98
13 13 7.4e-06 0.00053 20.9 0.7 1 23 498 520 498 520 0.98

Sequence Information

Coding Sequence
ATGTGTCCTGGTGCAATAATAGCGAAgCTTACCTCTGATGATAACAGATCTGCTAAAGTGTGCTACATATGTAATGCGCATTTGGAGAAATTTGTGAAGTTCTTTAATATATGCCAGAAATCAGAAAAAATATGCAGAGATCTATTCCAGAACAACATTGAGGTGACACCGGAGAACTTAGATAAGCATAACTTGAGATGGATATATAACTTATCAATATCACCACCGACATTGGTGTCCAATGAACTAGATGTCTCCATCAAGCTGGAAGAAGTTTCAATTGATCGAGCGATGTTGCCAATGGGGGAACTTAAAATCAAAAGTGAATGCAACGCACCGGACAAGGAATATGAAACTTGTGTTGAACAGTGTGTATCCACAAGTTCACCAGGTGGACATAATGAAACAACAGACACTAAAACCAAAACAAGAATTAGaacaaaaagtaaaaagctAGAAAGTAGTCACAATGTAGAAAAGTCATATAAATGTGATATTTGTAGCAAGTCTTATAAGAATAATTTCACTTTCAAAAGACACAGGAGACTTCATACTGGAGAAGAACCATATGCGTGCCAGATATGTACGGAAACATACAGTCAAATGGATTTATTAAATCTTCACATGCTCTCAAATCATTTAGCTGAAATGCCCACCTGTGATATATGCACCAAAAGGTTTTCTACAAAAACTCTTCTTAACAGGCATATCAAGCAAACCCACGAACAAAGCTCATTAACATGCAAAGTCtgttacaaaacatttaatatgaAACAACATTTAAATGCCCACATGAAGATACACATTGGATACAAGCCATTTGTTTGCAGTGCTtgtggtaaaacctttatagaAAGTGGTCAGTTAAAAGTCCACTCAAGAATACATTCTGGTAAAAAACCATTTGCCTGTGAGTTGTGCAACAAGTCATTTCGACAATTAAGTGAATTGCAAAGTCATATGCATCTCCATACTGGAGAAAAGCCATACATCTGCAAGGTTTGCAACAAGTCCTTCCGTCACCGCTACACACTGGCACTGCACTCTTTGCTCCACGCTGGTGAGAAGCCCTACACATGTCCTATATGTAAGAGCGTCTTTGATCTAAAGCCTCTTCTACACAAACATATAGCAAATCACACAGACAACTCCTCATATGTGTGCAAAATATGCAGCAAAGTATTTGTTCACAGTATTCTTTTGAAGCAACATGAGAAAATCCACTGGAATACAAAACGTTTTATGTGCGACATGTGCGGCTGGTCATTCTATACGAACTCGGCTTTAGTGAATCACATGACAAATCACACTGGAGAGAAGCCATTTACATGTGATGTATGTGAGAAATCTTTTCCTCATAAGAGAACTTTAGTGGCTCACAAACGGATACACACGGGTGAGAAGCCATACTCGTGTGACGTTTGCAACAAGAAATTTACTTTCACCCACGGCCTGAAcagacattttaaaatacacacTGGTGACAAACCATTTAGCTGCAGCATATGCAACATGTCTTTTATTGGAAATGATAAATTGAAAAGACATTTGAAAGTGCACAGTAAAGAAGAACCTTAG
Protein Sequence
MCPGAIIAKLTSDDNRSAKVCYICNAHLEKFVKFFNICQKSEKICRDLFQNNIEVTPENLDKHNLRWIYNLSISPPTLVSNELDVSIKLEEVSIDRAMLPMGELKIKSECNAPDKEYETCVEQCVSTSSPGGHNETTDTKTKTRIRTKSKKLESSHNVEKSYKCDICSKSYKNNFTFKRHRRLHTGEEPYACQICTETYSQMDLLNLHMLSNHLAEMPTCDICTKRFSTKTLLNRHIKQTHEQSSLTCKVCYKTFNMKQHLNAHMKIHIGYKPFVCSACGKTFIESGQLKVHSRIHSGKKPFACELCNKSFRQLSELQSHMHLHTGEKPYICKVCNKSFRHRYTLALHSLLHAGEKPYTCPICKSVFDLKPLLHKHIANHTDNSSYVCKICSKVFVHSILLKQHEKIHWNTKRFMCDMCGWSFYTNSALVNHMTNHTGEKPFTCDVCEKSFPHKRTLVAHKRIHTGEKPYSCDVCNKKFTFTHGLNRHFKIHTGDKPFSCSICNMSFIGNDKLKRHLKVHSKEEP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-